IRIS
MOZZARELLI, Andrea
 Distribuzione geografica
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Continente #
NA - Nord America 13.754
AS - Asia 11.453
EU - Europa 8.541
SA - Sud America 1.695
AF - Africa 554
OC - Oceania 16
Continente sconosciuto - Info sul continente non disponibili 14
Totale 36.027
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Nazione #
US - Stati Uniti d'America 13.377
SG - Singapore 4.146
CN - Cina 3.441
VN - Vietnam 1.720
IE - Irlanda 1.409
BR - Brasile 1.351
SE - Svezia 1.304
FI - Finlandia 1.262
IT - Italia 1.105
DE - Germania 1.025
HK - Hong Kong 885
UA - Ucraina 836
FR - Francia 388
ZA - Sudafrica 356
NL - Olanda 354
TR - Turchia 291
GB - Regno Unito 262
CA - Canada 242
IN - India 156
AR - Argentina 129
RU - Federazione Russa 129
AT - Austria 122
BD - Bangladesh 115
KR - Corea 101
IQ - Iraq 90
JP - Giappone 83
MX - Messico 78
ID - Indonesia 71
BE - Belgio 63
EC - Ecuador 62
CI - Costa d'Avorio 57
PL - Polonia 52
ES - Italia 50
PH - Filippine 49
PK - Pakistan 49
CZ - Repubblica Ceca 45
IR - Iran 39
MA - Marocco 36
VE - Venezuela 33
CO - Colombia 32
LT - Lituania 31
TH - Thailandia 27
UZ - Uzbekistan 27
KE - Kenya 26
SA - Arabia Saudita 25
PE - Perù 22
PY - Paraguay 22
CL - Cile 17
TN - Tunisia 17
EG - Egitto 16
MY - Malesia 16
RO - Romania 16
TW - Taiwan 16
UY - Uruguay 16
AE - Emirati Arabi Uniti 15
DZ - Algeria 13
IL - Israele 13
JO - Giordania 13
CR - Costa Rica 12
EU - Europa 12
RS - Serbia 11
AU - Australia 10
BO - Bolivia 9
HN - Honduras 9
NP - Nepal 9
ET - Etiopia 8
PT - Portogallo 8
AZ - Azerbaigian 7
DO - Repubblica Dominicana 7
JM - Giamaica 7
KG - Kirghizistan 7
MD - Moldavia 7
LU - Lussemburgo 6
NG - Nigeria 6
AM - Armenia 5
BG - Bulgaria 5
BY - Bielorussia 5
CH - Svizzera 5
EE - Estonia 5
KZ - Kazakistan 5
PA - Panama 5
PS - Palestinian Territory 5
AL - Albania 4
DK - Danimarca 4
GE - Georgia 4
HR - Croazia 4
HU - Ungheria 4
LB - Libano 4
NZ - Nuova Zelanda 4
OM - Oman 4
TT - Trinidad e Tobago 4
BN - Brunei Darussalam 3
GA - Gabon 3
GR - Grecia 3
GT - Guatemala 3
LV - Lettonia 3
MK - Macedonia 3
MT - Malta 3
QA - Qatar 3
SI - Slovenia 3
Totale 35.981
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Città #
Singapore 2.053
Ashburn 1.701
Chandler 1.415
Dublin 1.406
San Jose 1.125
Santa Clara 1.052
Jacksonville 907
Hong Kong 854
Beijing 851
Dearborn 628
Dallas 597
Ho Chi Minh City 483
Parma 446
Hanoi 428
Ann Arbor 417
Boardman 378
Nanjing 376
Johannesburg 336
Munich 281
Princeton 278
Los Angeles 263
Shanghai 257
New York 256
Lauterbourg 254
Izmir 221
San Mateo 213
Wilmington 201
Bremen 169
Helsinki 159
Shenyang 142
Toronto 141
Hefei 132
Buffalo 125
São Paulo 115
Jinan 109
Nanchang 101
Kunming 100
The Dalles 100
Vienna 95
Columbus 94
Council Bluffs 91
Hebei 91
Da Nang 81
Guangzhou 75
Seoul 75
Haiphong 72
Seattle 72
Moscow 70
Woodbridge 67
Tokyo 66
Turku 63
Tianjin 62
Changsha 60
Abidjan 57
Chicago 57
Brussels 53
Jiaxing 52
Des Moines 51
Houston 51
Marseille 49
Frankfurt am Main 48
Grafing 48
Milan 46
Brooklyn 43
Baghdad 40
London 40
Atlanta 39
Rio de Janeiro 37
Jakarta 36
Orem 36
Nuremberg 35
Warsaw 35
Leawood 33
Biên Hòa 32
Brno 32
Brasília 31
Hải Dương 31
Hangzhou 30
Montreal 30
Norwalk 30
Chennai 29
Falls Church 29
Phoenix 29
Belo Horizonte 28
Haikou 27
Auburn Hills 25
San Francisco 25
Tashkent 25
Nairobi 24
Stockholm 23
Bologna 22
Pune 22
Taiyuan 22
Boston 21
Curitiba 21
Guayaquil 21
Ottawa 21
Augusta 20
Rome 20
Zhengzhou 20
Totale 21.780
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Nome #
METODO PER LA DETERMINAZIONE DELL'ATTIVITA' DI ALFA-AMILASI 284
Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants 263
Ligand migration in non symbiotic hemoglobin AHb1 from Arabidopsis thaliana 233
Combination of SAXS and protein painting discloses the three-dimensional organization of the bacterial cysteine synthase complex, a potential target for enhancers of antibiotic action 226
High and low oxygen affinity conformations of T state hemoglobin 214
Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant 214
Tryptophan synthase: a mine for enzymologists 213
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP 211
ADIFAB fluorescence data used for the quantification of free fatty acids in media at different pH 207
Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution 205
Kinetics of acid-induced spectral changes in GFPmut2 chromophore 202
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase 197
Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms 193
Nuovi composti antimicrobici 193
Functional Characterization of Heme Proteins Encapsulated in Wet Nanoporous Silica Gels 190
A competitive o‐acetylserine sulfhydrylase inhibitor modulates the formation of cysteine synthase complex 190
Dynamics of Green Fluorescent Protein Mutant2 in Solution, on Spin-coated Glasses and Encapsulated in Wet Silica Gels 184
Allosteric communication of tryptophan synthase: functional and regulatory properties of the betaSer178Pro mutant 183
From hemoglobin allostery to hemoglobin-based oxygen carriers 183
Design and synthesis of trans-2-substituted-cyclopropane-1-carboxylic acids as the first non-natural small molecule inhibitors of O-acetylserine sulfhydrylase 176
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels 175
Phospholipid components of the synthetic pulmonary surfactant CHF5633 probed by fluorescence spectroscopy 175
Biocatalysis in a confined environment. Lessons from enzymes immobilized in wet, nanoporous silica gels 174
Identification of the Geometric Requirements for the Allosteric Communication between Alpha and Beta Subunits of Tryptophan Synthase 172
Geminate rebinding in R state hemoglobin: kinetic and computational evidence for multiple hydrophobic pockets 172
Rational Design, Synthesis and Preliminary Structure-Activity Relationships of α-Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella Typhimurium O-Acetylserine Sulfhydrylase 171
CO rebinding kinetics and molecular dynamics simulations highlight dynamic regulation of internal cavities in human cytoglobin 170
Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor 170
Conjugation to gold nanoparticles of methionine gamma-lyase, a cancer-starving enzyme. Physicochemical characterization of the nanocomplex for prospective nanomedicine applications 168
The Energy Landscape of Human Serine Racemase 167
SP-B and SP-C analogues within CHF5633 synthetic surfactant probed by fluorescence labeling 167
Allosteric communication between alpha and beta subunits of tryptophan synthase: modelling the open-closed transition of the alpha subunit 166
Evidence for Two Geminate Rebinding States Following Laser Photolysis of R State Hemoglobin Encapsulated in Wet Silica Gels 166
Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants 165
Allosteric regulation of tryptophan synthase: a pKa change at the beta-active site induced by alpha-subunit ligands 165
Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy 165
Structural insight into the interaction of O-acetylserine sulfhydrylase with competitive, peptidic inhibitors by Saturation Transfer Difference-NMR 165
L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase 164
Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana 163
Characterization of ligand migration mechanisms inside haemoglobins from the analysis of geminate rebinding kinetics 162
Chemistry and biochemistry of oxygen therapeutics: from transfusion to artificial blood 161
CO rebinding kinetics to high and low affinity T state hemoglobin encapsulated in silica gels 160
Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy 160
A two-step process controls the formation of the bienzyme cysteine synthase complex 159
Biochemical platform for the identification of adverse effects triggered by free hemoglobin in guinea pigs 159
From meat to food: the proteomics assessment 159
Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR 159
Determination of microscopic rate constants for CO binding and migration in myoglobin encapsulated in silica gels 158
Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality 158
Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95 156
Enhanced geminate ligand rebinding upon photo-dissociation of silica gels-embedded myoglobin-CO 156
ATP binding to human serine racemase is cooperative and modulated by glycine 156
Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes 155
A Key Silencing Histone Mark on Chromatin Is Lost When Colorectal Adenocarcinoma Cells Are Depleted of Methionine by Methionine γ-Lyase 155
Time-resolved methods in biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis 154
Post-Translational Modifications of Histone Variants in the Absence and Presence of a Methionine-Depleting Enzyme in Normal and Cancer Cells 153
Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase 153
CO rebinding kinetics to myoglobin- and R state hemoglobin-doped silica gels in the presence of glycerol 152
Surface-exposed Tryptophan Residues Are Essential for O-Acetylserine Sulfhydrylase Structure, Function and Stability 152
Correlation of protein functional properties in the crystal and in solution: the case study of T state hemoglobin 150
A computational method for the prediction of binding free energy between a protein receptor and its ligands 150
Conformational probes of O-acetylserine sulfhydrylase:fluorescence of tryptophans 50 and 161 150
48 hours after birth: what’s in the saliva of the baby? 150
Role of pyridoxal 5’-phosphate in the structural stabilization of O-acetylserine sulfhydrylase 150
Expanding the chemical space of human serine racemase inhibitors 150
Il contributo della microspettrofotometria allo studio della relazione fra struttura e funzione degli enzimi 149
Allosteric regulation of tryptophan synthase: effects of pH, temperature and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate L-serine intermediates 149
Design of O-acetylserine sulfhydrylase inhibitors by mimicking Nature. 148
Human serine racemase is nitrosylated at multiple sites 148
Time-resolved fluorescence of O-acetylserine sulfhydrylase 147
Effect of pH and monovalent cations on the formation of quinonoid intermediates of the tryptophan synthase alpha2beta2 complex in solution and in the crystal 146
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes 146
The molecular pathway for the allosteric regulation of tryptophan synthase 146
More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function 146
A fast empirical scoring method for docking and virtual screening 145
Allosteric effectors do not alter the oxygen affinity of hemoglobin crystals 144
Simple, intuitive calculations of free energy of binding for protein-ligand complexes: 1 Models without explicit constrained water 144
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. 143
Catalytic Activity of Aspartate Aminotransferase in the Crystal: Equilibrium and Kinetic Analysis 141
Characterization of tryptophan and coenzyme luminescence in tryptophan synthase from Salmonella typhimurium 141
Crystals of haemoglobin with the T quaternary structure bind oxygen noncooperatively with no Bohr effect 141
Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium 140
Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers 140
Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target 140
Computational titration analysis of a multiprotic HIV-1 protease-ligand complex 139
Crystal structure of the betaSer178Pro mutant of tryptophan synthase: a "knock-out" allosteric enzyme 139
Blocking cysteine biosynthesis in Salmonella typhimurium: the moonlighting enzyme CysK as a potential antibiotic target 139
Time-resolved fluorescence of O-acetylserine sulfhydrylase catalytic intermediates 139
Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design 139
Energy-based code for preferential amino acid-base recognition 138
Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana 138
Engineering methionine γ-lyase from Citrobacter freundii for anticancer activity 138
Is the protein profile of pig Longissimus dorsi affected by gender and diet? 137
The Reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is Controlled by the Distal HisE7 and Internal Hydrophobic Cavities 136
Allosteric Mechanism of Haemoglobin: Rupture of Salt-bridges Raises the Oxygen Affinity of T-structure 136
Enzyme Replacement Therapy for Genetic Disorders Associated with Enzyme Deficiency 136
Insight into GFPmut2 pH Dependence by Single Crystal Microspectrophotometry and X-ray Crystallography 136
Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes. 135
Chemogenomics of Pyridoxal 5’-phosphate Dependent Enzymes 135
High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model 135
Totale 16.337
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Categoria #
all - tutte 124.168
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 124.168
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021423 0 0 0 0 0 0 0 0 0 57 331 35
2021/20221.526 45 31 17 83 37 97 193 202 95 101 180 445
2022/20235.460 601 577 366 405 563 620 64 322 1.695 28 165 54
2023/20241.935 99 188 66 70 146 481 175 167 61 98 134 250
2024/20256.599 171 359 487 323 704 916 305 329 628 603 580 1.194
2025/202612.818 1.514 1.189 1.846 1.237 1.870 656 1.617 405 1.684 800 0 0
Totale 36.510