| Nome |
# |
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PEGylation Promotes Hemoglobin Tetramer Dissociation, file e177fbc4-199d-50b0-e053-d805fe0adaee
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112
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Pyridoxal 5’-phosphate enzymes as targets for terapeutic agents, file e177fbc4-1245-50b0-e053-d805fe0adaee
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104
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Muscle and meat: New horizons and applications for proteomics on a farm to fork perspective, file e177fbc4-3cbe-50b0-e053-d805fe0adaee
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71
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Muscle to meat” molecular events and technological transformations: the proteomics insight, file e177fbc4-2e13-50b0-e053-d805fe0adaee
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57
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Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy, file e177fbc7-5c2a-50b0-e053-d805fe0adaee
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34
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Exploring and exploiting allostery: Models, evolution, and drug targeting, file e177fbc4-2997-50b0-e053-d805fe0adaee
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33
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Chemogenomics of Pyridoxal 5’-phosphate Dependent Enzymes, file e177fbc4-3a38-50b0-e053-d805fe0adaee
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27
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Microspectrophotometry for structural enzymology, file e177fbc4-09b6-50b0-e053-d805fe0adaee
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25
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Hemocyanin from E. californicum encapsulated in silica gels: oxygen binding and conformational states, file e177fbc4-1473-50b0-e053-d805fe0adaee
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25
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Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling, file e177fbc4-3f83-50b0-e053-d805fe0adaee
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24
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Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration, file e177fbc4-17a4-50b0-e053-d805fe0adaee
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21
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Unfolding of pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence, file e177fbc4-11f3-50b0-e053-d805fe0adaee
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19
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A Key Silencing Histone Mark on Chromatin Is Lost When Colorectal Adenocarcinoma Cells Are Depleted of Methionine by Methionine γ-Lyase, file e177fbc7-8136-50b0-e053-d805fe0adaee
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19
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Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms, file e177fbc7-06a6-50b0-e053-d805fe0adaee
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17
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STRUCTURES OF GABA AMINOTRANSFERASE, A PYRIDOXAL 5'-PHOSPHATE AND [2FE-2S] CLUSTER CONTAINING ENZYME, COMPLEXED WITH THE ANTIEPILEPSY DRUG VIGABATRIN AND WITH GAMMA-ETHYNYLGABA, file e177fbc4-091c-50b0-e053-d805fe0adaee
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16
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A two-step process controls the formation of the bienzyme cysteine synthase complex, file e177fbc4-1f34-50b0-e053-d805fe0adaee
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16
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X-ray crystallography marries spectroscopy to unveil structure and function of biological macromolecules, file e177fbc4-292e-50b0-e053-d805fe0adaee
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16
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Unintended consequences? Water molecules at biological and crystallographic protein–protein interfaces, file e177fbc4-3cc2-50b0-e053-d805fe0adaee
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16
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Design of O-acetylserine sulfhydrylase inhibitors by mimicking Nature., file e177fbc4-1f37-50b0-e053-d805fe0adaee
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15
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Rational design of a user-friendly aptamer/peptide-based device for the detection of staphylococcus aureus, file e177fbc7-7abb-50b0-e053-d805fe0adaee
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15
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Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95, file 73e9504f-aa71-43ca-93ce-19c3de451f44
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13
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Tryptophan synthase: a mine for enzymologists, file e177fbc4-1b0c-50b0-e053-d805fe0adaee
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13
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Sulfur mobilization in cyanobacteria: The catalytic mechanism of L-cystine C-S lyase (C-DES) from Synechocystis, file e177fbc4-11f2-50b0-e053-d805fe0adaee
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12
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Development of a novel, hemolysis-resistant reagent for assessment of α-amylase in biological fluids, file e177fbc4-3cc0-50b0-e053-d805fe0adaee
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12
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Engineering tyrosine electron transfer pathways decreases oxidative toxicity in hemoglobin: implications for blood substitute design, file e177fbc5-340c-50b0-e053-d805fe0adaee
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12
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ATP binding to human serine racemase is cooperative and modulated by glycine, file e177fbc4-3cc4-50b0-e053-d805fe0adaee
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11
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Stability of Maleimide-PEG and Mono-Sulfone-PEG Conjugation to a Novel Engineered Cysteine in the Human Hemoglobin Alpha Subunit, file e177fbc7-652a-50b0-e053-d805fe0adaee
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10
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More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function, file e177fbc6-b307-50b0-e053-d805fe0adaee
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9
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A competitive o‐acetylserine sulfhydrylase inhibitor modulates the formation of cysteine synthase complex, file e177fbc7-49eb-50b0-e053-d805fe0adaee
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9
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Exploring the pyridoxal 5'-phosphate-dependent enzymes, file e177fbc4-1148-50b0-e053-d805fe0adaee
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8
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Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes, file e177fbc4-1469-50b0-e053-d805fe0adaee
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7
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Unfolding of Green Fluorescent Protein mut2 in Wet Nanoporous Silica Gels, file e177fbc4-0b4f-50b0-e053-d805fe0adaee
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5
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Evidence of discrete substates and unfolding pathways in Green Fluorescent Protein, file e177fbc4-12c0-50b0-e053-d805fe0adaee
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5
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Role of tertiary structures on the Root effect in fish hemoglobins, file e177fbc4-38e5-50b0-e053-d805fe0adaee
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5
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Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models, file e177fbc4-ed27-50b0-e053-d805fe0adaee
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5
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Human serine racemase is nitrosylated at multiple sites, file e177fbc6-094b-50b0-e053-d805fe0adaee
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5
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The Reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is Controlled by the Distal HisE7 and Internal Hydrophobic Cavities, file e177fbc4-133c-50b0-e053-d805fe0adaee
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4
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Evolution of allosteric models for hemoglobin, file e177fbc4-1497-50b0-e053-d805fe0adaee
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4
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Ligand migration through the internal hydrophobic cavities in human neuroglobin, file e177fbc4-1807-50b0-e053-d805fe0adaee
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4
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Enviromental effects on the oscillatory unfolding kinetics of GFP, file e177fbc4-2112-50b0-e053-d805fe0adaee
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4
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Role of tertiary structures on the Root effect in fish hemoglobins, file e177fbc4-38e1-50b0-e053-d805fe0adaee
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4
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Isozyme-specific ligands for O-acetylserine sulfhydrylase, a novel antibiotic target, file e177fbc4-3cc7-50b0-e053-d805fe0adaee
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4
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Immobilization of proteins in silica gel: Biochemical and biophysical properties, file e177fbc4-a20a-50b0-e053-d805fe0adaee
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4
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Rational Design, Synthesis and Preliminary Structure-Activity Relationships of α-Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella Typhimurium O-Acetylserine Sulfhydrylase, file e177fbc4-f89b-50b0-e053-d805fe0adaee
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4
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Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR, file e177fbc6-454a-50b0-e053-d805fe0adaee
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4
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SP-B and SP-C analogues within CHF5633 synthetic surfactant probed by fluorescence labeling, file e177fbc8-081e-50b0-e053-d805fe0adaee
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4
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Spectroscopic and functional characterization of T state hemoglobin conformations encapsulated in silica gels, file e177fbc4-0a31-50b0-e053-d805fe0adaee
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3
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Role of pyridoxal 5’-phosphate in the structural stabilization of O-acetylserine sulfhydrylase, file e177fbc4-11f5-50b0-e053-d805fe0adaee
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3
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Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes., file e177fbc4-97be-50b0-e053-d805fe0adaee
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3
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Moonlighting O-acetylserine sulfhydrylase: New functions for an old protein, file e177fbc4-9858-50b0-e053-d805fe0adaee
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3
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Experimental basis for a new allosteric model for multisubunit proteins, file e177fbc4-ed25-50b0-e053-d805fe0adaee
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3
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Structural insight into the interaction of O-acetylserine sulfhydrylase with competitive, peptidic inhibitors by Saturation Transfer Difference-NMR, file e177fbc4-f27a-50b0-e053-d805fe0adaee
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3
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Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport., file e177fbc5-387f-50b0-e053-d805fe0adaee
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3
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Ligand migration and hexacoordination in type 1 non symbiotic rice hemoglobin, file e177fbc5-3881-50b0-e053-d805fe0adaee
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3
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Geminate rebinding in R state hemoglobin: kinetic and computational evidence for multiple hydrophobic pockets, file e177fbc4-0ae5-50b0-e053-d805fe0adaee
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2
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Exploring the pyridoxal 5'-phosphate-dependent enzymes, file e177fbc4-1147-50b0-e053-d805fe0adaee
|
2
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Ligand migration in non symbiotic hemoglobin AHb1 from Arabidopsis thaliana, file e177fbc4-16a2-50b0-e053-d805fe0adaee
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2
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Design of O-acetylserine sulfhydrylase inhibitors by mimicking Nature., file e177fbc4-1f36-50b0-e053-d805fe0adaee
|
2
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New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels., file e177fbc4-2383-50b0-e053-d805fe0adaee
|
2
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null, file e177fbc4-23f9-50b0-e053-d805fe0adaee
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2
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Oxygen and Nitric Oxide Rebinding Kinetics in Nonsymbiotic Hemoglobin AHb1 from Arabidopsis thaliana, file e177fbc4-26d6-50b0-e053-d805fe0adaee
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2
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Expanding the chemical space of human serine racemase inhibitors, file e177fbc4-9857-50b0-e053-d805fe0adaee
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2
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Time-resolved methods in biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis, file e177fbc5-3883-50b0-e053-d805fe0adaee
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2
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Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana, file e177fbc5-424b-50b0-e053-d805fe0adaee
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2
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High and low oxygen affinity conformations of T state hemoglobin, file e177fbc5-44a3-50b0-e053-d805fe0adaee
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2
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Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels, file e177fbc5-44a6-50b0-e053-d805fe0adaee
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2
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Characterization of ligand migration mechanisms inside haemoglobins from the analysis of geminate rebinding kinetics, file e177fbc5-534a-50b0-e053-d805fe0adaee
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2
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Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP, file e177fbc6-3b7b-50b0-e053-d805fe0adaee
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2
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Engineering methionine γ-lyase from Citrobacter freundii for anticancer activity, file e177fbc6-46b7-50b0-e053-d805fe0adaee
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2
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Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants, file 215da461-14a8-4fbc-a89e-02c4ff6c808e
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1
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L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase, file 723ba317-6beb-4461-8dd5-17ac0d0b3850
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1
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Conjugation to gold nanoparticles of methionine gamma-lyase, a cancer-starving enzyme. Physicochemical characterization of the nanocomplex for prospective nanomedicine applications, file 84c4c3d1-3aef-4485-8d2a-030f9195fc3f
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1
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Microspectrophotometry for structural enzymology, file e177fbc4-0a33-50b0-e053-d805fe0adaee
|
1
|
|
Unfolding of Green Fluorescent Protein mut2 in Wet Nanoporous Silica Gels, file e177fbc4-0b4e-50b0-e053-d805fe0adaee
|
1
|
|
Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: Evidence from fluorescence spectroscopy, file e177fbc4-0b50-50b0-e053-d805fe0adaee
|
1
|
|
Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: Evidence from fluorescence spectroscopy, file e177fbc4-0b51-50b0-e053-d805fe0adaee
|
1
|
|
Evidence of discrete substates and unfolding pathways in Green Fluorescent Protein, file e177fbc4-12bf-50b0-e053-d805fe0adaee
|
1
|
|
Evolution of allosteric models for hemoglobin, file e177fbc4-1496-50b0-e053-d805fe0adaee
|
1
|
|
Robust classification of "Relevant" water molecules in putative protein binding sites, file e177fbc4-1b4d-50b0-e053-d805fe0adaee
|
1
|
|
ATP binding to human serine racemase is cooperative and modulated by glycine, file e177fbc4-3cc3-50b0-e053-d805fe0adaee
|
1
|
|
Regulation of human serine racemase activity and dynamics by halides, ATP and malonate, file e177fbc4-99e4-50b0-e053-d805fe0adaee
|
1
|
|
Molecular insights into dimerization inhibition of c-Maf transcription factor, file e177fbc4-a15b-50b0-e053-d805fe0adaee
|
1
|
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Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target, file e177fbc4-a2b1-50b0-e053-d805fe0adaee
|
1
|
|
The multifaceted pyridoxal 5’-phosphate-dependent O-acetylserine sulfhydrylase, file e177fbc4-ed24-50b0-e053-d805fe0adaee
|
1
|
|
Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy, file e177fbc4-ed5e-50b0-e053-d805fe0adaee
|
1
|
|
Protein crystal microspectrophotometry, file e177fbc4-f273-50b0-e053-d805fe0adaee
|
1
|
|
Insight of Saffron Proteome by Gel-Electrophoresis, file e177fbc4-f35a-50b0-e053-d805fe0adaee
|
1
|
|
Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes, file e177fbc5-2cef-50b0-e053-d805fe0adaee
|
1
|
|
Structural Plasticity and Functional Implications of Internal Cavities in Distal Mutants of Type 1 Non-Symbiotic Hemoglobin AHb1 from Arabidopsis thaliana, file e177fbc5-477a-50b0-e053-d805fe0adaee
|
1
|
|
Determination of microscopic rate constants for CO binding and migration in myoglobin encapsulated in silica gels, file e177fbc5-4c70-50b0-e053-d805fe0adaee
|
1
|
|
Evidence for Two Geminate Rebinding States Following Laser Photolysis of R State Hemoglobin Encapsulated in Wet Silica Gels, file e177fbc5-4e69-50b0-e053-d805fe0adaee
|
1
|
|
Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana, file e177fbc5-4e72-50b0-e053-d805fe0adaee
|
1
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|
Enhanced geminate ligand rebinding upon photo-dissociation of silica gels-embedded myoglobin-CO, file e177fbc5-4f17-50b0-e053-d805fe0adaee
|
1
|
|
Functional Characterization of Heme Proteins Encapsulated in Wet Nanoporous Silica Gels, file e177fbc5-5083-50b0-e053-d805fe0adaee
|
1
|
|
Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin., file e177fbc5-52c0-50b0-e053-d805fe0adaee
|
1
|
|
CO rebinding kinetics and molecular dynamics simulations highlight dynamic regulation of internal cavities in human cytoglobin, file e177fbc5-5361-50b0-e053-d805fe0adaee
|
1
|
|
Modulation of Escherichia coli serine acetyltransferase catalytic activity in the cysteine synthase complex, file e177fbc5-7584-50b0-e053-d805fe0adaee
|
1
|
|
Serine racemase: a key player in neuron activity and in neuropathologies, file e177fbc5-7ad5-50b0-e053-d805fe0adaee
|
1
|
|
Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase, file e177fbc5-e2e3-50b0-e053-d805fe0adaee
|
1
|
|
Surface-exposed Tryptophan Residues Are Essential for O-Acetylserine Sulfhydrylase Structure, Function and Stability, file e177fbc5-e42d-50b0-e053-d805fe0adaee
|
1
|
| Totale |
948 |