BONELLI, Mara
 Distribuzione geografica
Continente #
NA - Nord America 3.085
EU - Europa 2.947
AS - Asia 1.472
AF - Africa 39
SA - Sud America 9
OC - Oceania 3
Totale 7.555
Nazione #
US - Stati Uniti d'America 3.050
CN - Cina 838
IT - Italia 630
IE - Irlanda 554
FI - Finlandia 514
SE - Svezia 466
SG - Singapore 432
DE - Germania 281
UA - Ucraina 257
TR - Turchia 110
GB - Regno Unito 62
IN - India 56
BE - Belgio 53
FR - Francia 49
CI - Costa d'Avorio 38
CA - Canada 35
AT - Austria 31
NL - Olanda 14
CZ - Repubblica Ceca 10
HK - Hong Kong 10
IR - Iran 8
VN - Vietnam 8
JP - Giappone 5
AR - Argentina 4
PL - Polonia 4
RO - Romania 4
BR - Brasile 3
CH - Svizzera 3
HU - Ungheria 3
LT - Lituania 3
NZ - Nuova Zelanda 3
RU - Federazione Russa 3
ES - Italia 2
LU - Lussemburgo 2
PK - Pakistan 2
AE - Emirati Arabi Uniti 1
EC - Ecuador 1
EG - Egitto 1
HR - Croazia 1
JO - Giordania 1
KR - Corea 1
PE - Perù 1
SI - Slovenia 1
Totale 7.555
Città #
Dublin 554
Chandler 496
Ann Arbor 368
Singapore 335
Jacksonville 291
Dearborn 192
Beijing 173
Parma 173
Boardman 160
Ashburn 147
Nanjing 128
Izmir 110
Bremen 98
Princeton 98
Shanghai 98
San Mateo 86
Milan 64
New York 64
Santa Clara 63
Wilmington 60
Woodbridge 47
Helsinki 44
Hefei 42
Nanchang 42
Shenyang 42
Chicago 39
Abidjan 38
Kunming 38
Hebei 36
Brussels 35
Jinan 33
Des Moines 31
Vienna 30
Los Angeles 28
Pune 28
Toronto 26
Marseille 25
Modena 24
Tianjin 23
Redmond 22
Jiaxing 21
Seattle 20
Dallas 18
Houston 18
Norwalk 18
Changsha 17
Guangzhou 15
Leawood 14
Fremont 12
Munich 12
Wayne 12
London 11
Rome 11
Hangzhou 10
Hong Kong 10
Verona 9
Amsterdam 8
Ardabil 8
Augusta 8
Dong Ket 8
Fuzhou 8
Grafing 8
Taiyuan 8
Binche 7
Frankfurt am Main 7
Leuven 7
Auburn Hills 6
Chengdu 6
Florence 6
Follonica 6
Manchester 6
Monmouth Junction 6
Montreal 6
Ningbo 6
Reggio Emilia 6
Salsomaggiore Terme 6
Zhengzhou 6
Bologna 5
Borås 5
Brno 5
Fidenza 5
Genoa 5
Lanzhou 5
Mumbai 5
Redwood City 5
Casalgrande 4
Düsseldorf 4
Fairfield 4
Huizen 4
Kolkata 4
Mestre 4
Mons 4
Neviano degli Arduini 4
Phoenix 4
Rockville 4
Soliera 4
Xian 4
Albano Laziale 3
Bari 3
Bergamo 3
Totale 4.899
Nome #
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 208
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC 128
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 126
Characterization of gefitinib uptake in NSCLC cell lines 114
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 114
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 109
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 108
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance 105
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis 104
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations. 101
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method 99
Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung 99
Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity 98
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 95
Anti-proliferative effect of combining Letrozole with Sorafenib in MCF-7/Arom-1 breast cancer cells 95
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification 94
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 93
Osmotic regulation of ATA2 mRNA expression and amino acid transport system A activity 93
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines 92
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation 90
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines 89
Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines 89
Attenuated expression of 70kDa heat shock protein in WI-38 human fibroblasts during aging in vitro 88
Anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM-1 breast cancer cells 88
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines 86
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress 85
Meccanismo d’azione di UPR 1024: un nuovo farmaco con attività antiproliferativa in cellule di carcinoma polmonare umano 85
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer 85
Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines 83
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. (Cavazzoni and Bonelli co-first authors) 83
Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells 82
New treatment opportunities in phosphatase and tensin homolo(PTen)-deficient tumors: Focus on PTen/focal adhesion kinase pathway 81
Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations 80
Anti-proliferative and pro-apoptotic effects of Sorafenib in breast cancer cells in vitro. 80
5-benzylidene-hydantoin UPR 1024 acts as EGFR inhibitor and induces DNA damage in A549 NSCLC cell line 79
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 79
Attenuata induzione del gene SNAT-2 in fibroblasti umani senescenti esposti a stress iperosmolare 78
Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity 77
Hypertonic stress and amino acid deprivation both increase expression of mRNA for amino acid transport system A 77
The effect of heat shock on amino acid transport and cell volume in 3T3 cells 76
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines 76
Synergistic activity of letrozole and sorafenib on MCF7/AROM-1 breast cancer cells 76
CDK4/6 INHIBITORS AS A NEW THERAPEUTIC APPROACH IN MESOTHELIOMA MODELS 75
Alterazioni della degradazione proteasoma-dipendente nel corso dell'invecchiamento ed effetti delle restrizioni caloriche 75
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 75
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 75
Induzione di osmotolleranza in cellule endoteliali derivate da arteria polmonare 74
Induzione di sistemi di trasporto in condizioni di stress ipertonico 74
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 72
Multiple effects of CDK4/6 inhibition in cancer: From cell cycle arrest to immunomodulation 71
CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells 70
Alterazioni della degradazione proteasoma-dipendente nel corso dell’invecchiamento ed effetti delle restrizioni caloriche 70
Anti-proliferative and pro-apoptotic effects of soarfenib in MCF-7/AROM-1 breast cancer cells. 69
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis 69
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 69
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones 67
Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines 66
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 66
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models 65
PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC) 65
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 64
Effect of proteasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 63
Effects of FGFR1 inhibition on survival, proliferation, and energy metabolism in Non Small Cell Lung Cancer (NSCLC) cell lines 63
L'inibizione dell'attività proteasomica ripristina la capacità dei fibroblasti umani senescenti di rispondere allo shock termico 63
Overcoming resistance of EGFR tyrosine kinase inhibitors by new cytostatic and proapoptotic drugs in non small cell lung cancer cell lines 62
Increased level of inducible HSP70 in cells exposed to electromagnetic fields. 61
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti. 60
Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts 60
Effect of letrozole and sorafenib on cell proliferation and apoptosis of MCF-7/AROM-1 breast cancer cell line 58
Attenuata induzione del gene snat2 in fibroblasti umani senescenti sottoposti a stress iperosmolare 58
Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK-mTORC1 signaling 58
Erlotinib potentiates Cetuximab-dependent call citotoxicity in EGFR wild type NSCLC cell lines 58
Risposta adattativa di cellule endoteliali a stress iperosmolare 57
Synergic anti-proliferative effect of gefitinib and RAD001 in non small cell lung cancer cell lines 57
Targeting oncogenic PI3K/Akt/mTOR pathway in squamous cell lung carcinoma 56
L’inibizione proteasomica ripristina in cellule senescenti l’espressione di HSP70 55
Synergistic activity of letrozole and sorafenib on breast cancer cells 55
Effetto dell’inibizione proteasomica sull’espressione del gene HSP70 in cellule senescenti. 54
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines 54
Evaluation of gefitinib maintenance in an EGFR-mutant NSCLC cell line with acquired resistance 53
Espressione Inducibile del gene FHIT in cellule di carcinoma polmonare 53
Immunotherapeutic approaches in malignant pleural mesothelioma 53
Hyperosmotic stress response 53
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines 53
Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro 52
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti 51
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer 51
Low-level caloric restriction rescues proteasome activity and hsc70 level in liver of aged rats 51
Effect of protesasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 50
Increased level of 70-kDa Heat Shock Protein in human cells exposed to electromagnetic fields. 49
Induzione differenziale da ipertonicità delle attività di trasporto dei sistemi A e BGT-1 in cellule endoteliali 49
Shiga toxin 1 and ricin inhibit thr repair of H2O2-induced DNA single strand breks in cultured mammalian cells 49
Proteasome inhibition restores accumulation of HSP72 and HuR proteins in human fibroblasts aged in vitro 49
Erlotinib potentiates Cetuximab-dependent cell citotoxicity in EGFR wild-type NSCLC cell lines 49
Hyperosmotic stress response 48
New therapeutic strategies for malignant pleural mesothelioma 47
Pure anti-tumor effect of zoledronic acid in naive bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy" 46
Targeting FGFR1 pathway in squamous cell lung cancer 45
Synergic anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM breast cancer cells 45
Evaluation of gefitinib maintenance in an EGFR-mutant NSCL cell line with acquired resistance 45
Totale 7.391
Categoria #
all - tutte 28.830
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.830


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020881 0 0 0 0 95 152 201 55 119 112 53 94
2020/2021752 13 77 62 37 88 14 74 31 133 24 162 37
2021/2022560 30 19 27 47 19 10 86 61 31 38 37 155
2022/20232.100 222 205 136 141 236 233 17 115 671 7 91 26
2023/2024892 38 64 31 39 67 187 65 70 36 51 95 149
2024/2025817 93 148 175 186 215 0 0 0 0 0 0 0
Totale 7.722