IRIS
BONELLI, Mara
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 5.878
AS - Asia 4.778
EU - Europa 3.997
SA - Sud America 674
AF - Africa 257
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 1
Totale 15.596
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.754
SG - Singapore 1.588
CN - Cina 1.394
IT - Italia 1.005
VN - Vietnam 767
IE - Irlanda 545
FI - Finlandia 539
BR - Brasile 525
SE - Svezia 481
DE - Germania 398
HK - Hong Kong 330
UA - Ucraina 266
FR - Francia 181
ZA - Sudafrica 157
BD - Bangladesh 146
NL - Olanda 139
TR - Turchia 129
GB - Regno Unito 120
IN - India 120
RU - Federazione Russa 102
CA - Canada 75
AR - Argentina 58
BE - Belgio 58
AT - Austria 46
CI - Costa d'Avorio 40
IQ - Iraq 34
KR - Corea 34
PL - Polonia 31
JP - Giappone 30
ID - Indonesia 29
MX - Messico 29
EC - Ecuador 26
CO - Colombia 23
ES - Italia 23
PK - Pakistan 21
PH - Filippine 19
MA - Marocco 17
TH - Thailandia 14
CZ - Repubblica Ceca 13
SA - Arabia Saudita 13
VE - Venezuela 11
IR - Iran 10
JO - Giordania 10
KE - Kenya 10
LT - Lituania 10
UZ - Uzbekistan 10
EG - Egitto 9
PY - Paraguay 9
MY - Malesia 8
AU - Australia 7
RO - Romania 7
AL - Albania 6
AZ - Azerbaigian 6
CL - Cile 6
KG - Kirghizistan 6
OM - Oman 6
PS - Palestinian Territory 6
TN - Tunisia 6
TW - Taiwan 6
UY - Uruguay 6
GE - Georgia 5
HU - Ungheria 5
JM - Giamaica 5
NP - Nepal 5
PE - Perù 5
SY - Repubblica araba siriana 5
BO - Bolivia 4
DZ - Algeria 4
LB - Libano 4
LU - Lussemburgo 4
MD - Moldavia 4
NZ - Nuova Zelanda 4
PA - Panama 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
ET - Etiopia 3
HN - Honduras 3
KZ - Kazakistan 3
QA - Qatar 3
SN - Senegal 3
AM - Armenia 2
BB - Barbados 2
BG - Bulgaria 2
BW - Botswana 2
CY - Cipro 2
GA - Gabon 2
IL - Israele 2
LA - Repubblica Popolare Democratica del Laos 2
PT - Portogallo 2
AD - Andorra 1
AO - Angola 1
BH - Bahrain 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
HR - Croazia 1
KH - Cambogia 1
KW - Kuwait 1
Totale 15.582
Salva come PNG Salva come JPEG
Città #
Singapore 802
Ashburn 576
Dallas 575
Dublin 544
San Jose 518
Chandler 480
Ann Arbor 368
Beijing 332
Santa Clara 323
Hong Kong 311
Jacksonville 292
Parma 256
Ho Chi Minh City 238
Dearborn 192
Boardman 172
Hanoi 155
Johannesburg 149
Los Angeles 132
Nanjing 130
New York 124
Izmir 110
Lauterbourg 102
Shanghai 102
Princeton 98
Bremen 97
Hefei 97
Milan 92
Munich 87
San Mateo 86
Council Bluffs 81
Chicago 63
Wilmington 60
São Paulo 55
Helsinki 48
Woodbridge 47
Moscow 46
Bologna 43
Nanchang 43
Shenyang 42
Buffalo 41
Abidjan 40
Brussels 40
Toronto 39
Haiphong 38
Kunming 38
Vienna 38
Hebei 36
Modena 36
Jinan 35
Des Moines 32
Columbus 28
Houston 28
Pune 28
Da Nang 27
Seattle 27
The Dalles 27
Tianjin 27
Marseille 26
Frankfurt am Main 25
Warsaw 25
Changsha 22
Jiaxing 22
Redmond 22
Rome 22
Seoul 22
Stockholm 22
Tokyo 22
Denver 21
Jakarta 21
London 21
Turku 21
Guangzhou 19
Norwalk 18
Reggio Emilia 18
Levanto 17
Manchester 17
Nuremberg 17
Phoenix 17
Rio de Janeiro 17
Orem 16
Bari 14
Brooklyn 14
Leawood 14
Montreal 14
Amsterdam 13
Baghdad 13
Brescia 13
Dhaka 13
New Delhi 13
Atlanta 12
Belo Horizonte 12
Brasília 12
Chennai 12
Fremont 12
Wayne 12
Biên Hòa 11
Hangzhou 11
Hải Dương 11
San Francisco 11
Boston 10
Totale 9.390
Salva come PNG Salva come JPEG
Nome #
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 350
Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines 268
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 251
PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC) 251
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models 246
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 220
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 215
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 211
CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells 207
Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung 203
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 202
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC 198
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 197
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments 195
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance 194
Characterization of gefitinib uptake in NSCLC cell lines 190
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress 185
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 185
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method 185
Anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM-1 breast cancer cells 183
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis 182
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation 180
5-benzylidene-hydantoin UPR 1024 acts as EGFR inhibitor and induces DNA damage in A549 NSCLC cell line 179
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines 178
Anti-proliferative effect of combining Letrozole with Sorafenib in MCF-7/Arom-1 breast cancer cells 178
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification 178
Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines 176
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations. 175
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer 174
Corrigendum: CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells (Frontiers in Oncology, (2022), 12, (942341), 10.3389/fonc.2022.942341) 173
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines 171
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 171
Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity 170
Attenuated expression of 70kDa heat shock protein in WI-38 human fibroblasts during aging in vitro 166
Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations 163
CDK4/6 INHIBITORS AS A NEW THERAPEUTIC APPROACH IN MESOTHELIOMA MODELS 161
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines 161
Meccanismo d’azione di UPR 1024: un nuovo farmaco con attività antiproliferativa in cellule di carcinoma polmonare umano 159
Attenuata induzione del gene SNAT-2 in fibroblasti umani senescenti esposti a stress iperosmolare 159
Effects of FGFR1 inhibition on survival, proliferation, and energy metabolism in Non Small Cell Lung Cancer (NSCLC) cell lines 158
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 158
Anti-proliferative and pro-apoptotic effects of Sorafenib in breast cancer cells in vitro. 157
Anti-proliferative and pro-apoptotic effects of soarfenib in MCF-7/AROM-1 breast cancer cells. 149
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines 149
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. (Cavazzoni and Bonelli co-first authors) 148
Synergistic activity of letrozole and sorafenib on breast cancer cells 147
Osmotic regulation of ATA2 mRNA expression and amino acid transport system A activity 147
Alterazioni della degradazione proteasoma-dipendente nel corso dell'invecchiamento ed effetti delle restrizioni caloriche 146
Alterazioni della degradazione proteasoma-dipendente nel corso dell’invecchiamento ed effetti delle restrizioni caloriche 145
New treatment opportunities in phosphatase and tensin homolo(PTen)-deficient tumors: Focus on PTen/focal adhesion kinase pathway 140
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 140
Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells 139
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 136
Immunotherapeutic approaches in malignant pleural mesothelioma 136
Attenuata induzione del gene snat2 in fibroblasti umani senescenti sottoposti a stress iperosmolare 133
Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines 133
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 132
Hypertonic stress and amino acid deprivation both increase expression of mRNA for amino acid transport system A 131
Synergistic activity of letrozole and sorafenib on MCF7/AROM-1 breast cancer cells 130
Correction to: Pemetrexed Enhances Membrane PD-L1 Expression and Potentiates T Cell-Mediated Cytotoxicity by Anti-PD-L1 Antibody Therapy in Non-Small-Cell Lung Cancer (Cancers, (2020), 12, 3, (666), 10.3390/cancers12030666) 129
Multiple effects of CDK4/6 inhibition in cancer: From cell cycle arrest to immunomodulation 129
null 126
The effect of heat shock on amino acid transport and cell volume in 3T3 cells 124
Induzione di sistemi di trasporto in condizioni di stress ipertonico 122
Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity 121
Targeting oncogenic PI3K/Akt/mTOR pathway in squamous cell lung carcinoma 120
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones 119
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 118
Induzione di osmotolleranza in cellule endoteliali derivate da arteria polmonare 117
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis 117
Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts 114
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines 112
L’inibizione proteasomica ripristina in cellule senescenti l’espressione di HSP70 111
Pure anti-tumor effect of zoledronic acid in naive bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy" 111
Hyperosmotic stress response 109
Effect of proteasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 106
Inhibition of Human Malignant Pleural Mesothelioma Growth by Mesenchymal Stromal Cells 105
Overcoming resistance of EGFR tyrosine kinase inhibitors by new cytostatic and proapoptotic drugs in non small cell lung cancer cell lines 104
Espressione Inducibile del gene FHIT in cellule di carcinoma polmonare 104
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines 104
Increased level of 70-kDa Heat Shock Protein in human cells exposed to electromagnetic fields. 103
Synergic anti-proliferative effect of gefitinib and RAD001 in non small cell lung cancer cell lines 103
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti. 101
Risposta adattativa di cellule endoteliali a stress iperosmolare 100
Effect of letrozole and sorafenib on cell proliferation and apoptosis of MCF-7/AROM-1 breast cancer cell line 99
Targeting FGFR1 pathway in squamous cell lung cancer 98
Increased level of inducible HSP70 in cells exposed to electromagnetic fields. 98
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer 97
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti 95
Induzione differenziale da ipertonicità delle attività di trasporto dei sistemi A e BGT-1 in cellule endoteliali 94
Effect of protesasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 94
Intrinsic Resistance to Osimertinib in EGFR Mutated NSCLC Cell Lines Induced by Alteration in Cell-Cycle Regulators 93
Shiga toxin 1 and ricin inhibit thr repair of H2O2-induced DNA single strand breks in cultured mammalian cells 93
Proteasome inhibition restores accumulation of HSP72 and HuR proteins in human fibroblasts aged in vitro 93
Erlotinib potentiates Cetuximab-dependent call citotoxicity in EGFR wild type NSCLC cell lines 93
L'inibizione dell'attività proteasomica ripristina la capacità dei fibroblasti umani senescenti di rispondere allo shock termico 93
Evaluation of gefitinib maintenance in an EGFR-mutant NSCLC cell line with acquired resistance 92
Hyperosmotic stress response 92
Effetto dell’inibizione proteasomica sull’espressione del gene HSP70 in cellule senescenti. 91
Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro 90
Totale 14.778
Salva come PNG Salva come JPEG
Categoria #
all - tutte 52.781
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.781
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022560 30 19 27 47 19 10 86 61 31 38 37 155
2022/20232.062 222 200 133 130 235 229 17 114 658 7 91 26
2023/2024880 38 62 30 39 66 186 64 66 36 51 95 147
2024/20252.729 93 146 173 185 239 284 173 138 340 236 257 465
2025/20266.068 491 560 786 579 851 314 667 194 820 403 229 174
2026/2027128 128 0 0 0 0 0 0 0 0 0 0 0
Totale 15.780