IRIS
BONELLI, Mara
 Distribuzione geografica
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Continente #
NA - Nord America 4.875
EU - Europa 3.655
AS - Asia 3.622
SA - Sud America 601
AF - Africa 201
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 1
Totale 12.961
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Nazione #
US - Stati Uniti d'America 4.781
SG - Singapore 1.455
CN - Cina 1.269
IT - Italia 817
IE - Irlanda 542
FI - Finlandia 539
BR - Brasile 491
SE - Svezia 478
DE - Germania 387
UA - Ucraina 266
HK - Hong Kong 262
VN - Vietnam 223
NL - Olanda 135
TR - Turchia 121
ZA - Sudafrica 120
GB - Regno Unito 114
RU - Federazione Russa 101
IN - India 96
FR - Francia 69
CA - Canada 63
BE - Belgio 58
AT - Austria 46
AR - Argentina 43
CI - Costa d'Avorio 40
PL - Polonia 27
BD - Bangladesh 25
ID - Indonesia 24
ES - Italia 21
KR - Corea 21
EC - Ecuador 20
MX - Messico 20
IQ - Iraq 19
JP - Giappone 17
CO - Colombia 14
PK - Pakistan 14
MA - Marocco 13
CZ - Repubblica Ceca 12
IR - Iran 10
LT - Lituania 9
PY - Paraguay 9
UZ - Uzbekistan 9
VE - Venezuela 9
KE - Kenya 8
AZ - Azerbaigian 6
JO - Giordania 6
KG - Kirghizistan 6
PS - Palestinian Territory 6
TN - Tunisia 6
AL - Albania 5
EG - Egitto 5
RO - Romania 5
UY - Uruguay 5
HU - Ungheria 4
LU - Lussemburgo 4
NP - Nepal 4
NZ - Nuova Zelanda 4
PE - Perù 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
CL - Cile 3
LB - Libano 3
MD - Moldavia 3
PA - Panama 3
SN - Senegal 3
SY - Repubblica araba siriana 3
AM - Armenia 2
AU - Australia 2
BG - Bulgaria 2
BO - Bolivia 2
BW - Botswana 2
CY - Cipro 2
GE - Georgia 2
HN - Honduras 2
KZ - Kazakistan 2
MY - Malesia 2
QA - Qatar 2
SA - Arabia Saudita 2
AD - Andorra 1
AO - Angola 1
BB - Barbados 1
BH - Bahrain 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
HR - Croazia 1
IL - Israele 1
JM - Giamaica 1
KW - Kuwait 1
LK - Sri Lanka 1
LV - Lettonia 1
NO - Norvegia 1
OM - Oman 1
PT - Portogallo 1
RS - Serbia 1
SI - Slovenia 1
Totale 12.958
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Città #
Singapore 751
Dallas 569
Dublin 542
Ashburn 513
Chandler 480
Ann Arbor 368
Beijing 327
Santa Clara 314
Jacksonville 291
Hong Kong 262
Parma 232
Dearborn 192
Boardman 168
Nanjing 129
Johannesburg 113
Izmir 110
New York 102
Los Angeles 99
Shanghai 99
Princeton 98
Bremen 97
Hefei 97
Munich 87
San Mateo 86
Milan 79
Ho Chi Minh City 76
Wilmington 60
Chicago 51
São Paulo 51
Helsinki 48
Woodbridge 47
Moscow 46
Nanchang 43
Shenyang 42
Abidjan 40
Brussels 40
Hanoi 40
Kunming 38
Vienna 38
Hebei 36
Toronto 35
Jinan 34
Buffalo 33
Des Moines 31
Columbus 28
Pune 28
Tianjin 27
Modena 26
Marseille 25
Seattle 25
Bologna 24
Houston 24
Warsaw 23
Jiaxing 22
Redmond 22
The Dalles 22
Changsha 21
Turku 21
Council Bluffs 20
Jakarta 20
London 20
Seoul 20
Denver 19
Stockholm 19
Guangzhou 18
Norwalk 18
Nuremberg 17
Rio de Janeiro 17
Frankfurt am Main 16
Manchester 16
Rome 16
Phoenix 15
Leawood 14
Tokyo 14
Amsterdam 13
Bari 13
Haiphong 13
Montreal 13
Reggio Emilia 13
San Jose 13
Belo Horizonte 12
Brasília 12
Brescia 12
Fremont 12
Wayne 12
Brooklyn 11
Chennai 11
Hangzhou 10
Poplar 10
Augusta 9
Baghdad 9
Campinas 9
Florence 9
San Francisco 9
Taiyuan 9
Verona 9
Zhengzhou 9
Ardabil 8
Boston 8
Dhaka 8
Totale 7.927
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Nome #
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 314
Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines 222
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 208
PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC) 206
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models 204
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 186
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 181
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 180
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC 170
Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung 166
Characterization of gefitinib uptake in NSCLC cell lines 165
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 165
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 165
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance 163
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis 160
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer 158
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation 157
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method 156
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations. 154
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress 151
Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations 150
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 150
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines 149
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification 149
Anti-proliferative effect of combining Letrozole with Sorafenib in MCF-7/Arom-1 breast cancer cells 148
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines 147
Anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM-1 breast cancer cells 147
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments 147
Attenuated expression of 70kDa heat shock protein in WI-38 human fibroblasts during aging in vitro 142
Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines 142
Meccanismo d’azione di UPR 1024: un nuovo farmaco con attività antiproliferativa in cellule di carcinoma polmonare umano 141
Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity 141
CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells 140
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 139
Attenuata induzione del gene SNAT-2 in fibroblasti umani senescenti esposti a stress iperosmolare 137
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 137
5-benzylidene-hydantoin UPR 1024 acts as EGFR inhibitor and induces DNA damage in A549 NSCLC cell line 137
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines 136
Corrigendum: CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells (Frontiers in Oncology, (2022), 12, (942341), 10.3389/fonc.2022.942341) 135
Effects of FGFR1 inhibition on survival, proliferation, and energy metabolism in Non Small Cell Lung Cancer (NSCLC) cell lines 133
Osmotic regulation of ATA2 mRNA expression and amino acid transport system A activity 131
CDK4/6 INHIBITORS AS A NEW THERAPEUTIC APPROACH IN MESOTHELIOMA MODELS 130
Anti-proliferative and pro-apoptotic effects of Sorafenib in breast cancer cells in vitro. 130
Alterazioni della degradazione proteasoma-dipendente nel corso dell’invecchiamento ed effetti delle restrizioni caloriche 129
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. (Cavazzoni and Bonelli co-first authors) 127
Alterazioni della degradazione proteasoma-dipendente nel corso dell'invecchiamento ed effetti delle restrizioni caloriche 124
New treatment opportunities in phosphatase and tensin homolo(PTen)-deficient tumors: Focus on PTen/focal adhesion kinase pathway 124
Anti-proliferative and pro-apoptotic effects of soarfenib in MCF-7/AROM-1 breast cancer cells. 121
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines 121
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 119
Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells 118
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 115
Attenuata induzione del gene snat2 in fibroblasti umani senescenti sottoposti a stress iperosmolare 114
Synergistic activity of letrozole and sorafenib on MCF7/AROM-1 breast cancer cells 114
Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines 111
Hypertonic stress and amino acid deprivation both increase expression of mRNA for amino acid transport system A 111
Induzione di sistemi di trasporto in condizioni di stress ipertonico 110
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 110
Multiple effects of CDK4/6 inhibition in cancer: From cell cycle arrest to immunomodulation 110
Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity 106
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis 105
The effect of heat shock on amino acid transport and cell volume in 3T3 cells 104
Targeting oncogenic PI3K/Akt/mTOR pathway in squamous cell lung carcinoma 104
Induzione di osmotolleranza in cellule endoteliali derivate da arteria polmonare 103
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 102
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones 101
Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts 100
Immunotherapeutic approaches in malignant pleural mesothelioma 99
Hyperosmotic stress response 94
L’inibizione proteasomica ripristina in cellule senescenti l’espressione di HSP70 93
Espressione Inducibile del gene FHIT in cellule di carcinoma polmonare 93
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines 92
Effect of proteasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 91
Overcoming resistance of EGFR tyrosine kinase inhibitors by new cytostatic and proapoptotic drugs in non small cell lung cancer cell lines 90
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti. 89
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines 88
Effect of letrozole and sorafenib on cell proliferation and apoptosis of MCF-7/AROM-1 breast cancer cell line 87
Synergistic activity of letrozole and sorafenib on breast cancer cells 87
Synergic anti-proliferative effect of gefitinib and RAD001 in non small cell lung cancer cell lines 87
Risposta adattativa di cellule endoteliali a stress iperosmolare 86
Inhibition of Human Malignant Pleural Mesothelioma Growth by Mesenchymal Stromal Cells 86
Increased level of inducible HSP70 in cells exposed to electromagnetic fields. 86
Effetto dell’inibizione proteasomica sull’espressione del gene HSP70 in cellule senescenti. 84
Effect of protesasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 84
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer 84
Erlotinib potentiates Cetuximab-dependent call citotoxicity in EGFR wild type NSCLC cell lines 84
L'inibizione dell'attività proteasomica ripristina la capacità dei fibroblasti umani senescenti di rispondere allo shock termico 84
Pure anti-tumor effect of zoledronic acid in naive bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy" 83
Targeting FGFR1 pathway in squamous cell lung cancer 83
Shiga toxin 1 and ricin inhibit thr repair of H2O2-induced DNA single strand breks in cultured mammalian cells 83
Increased level of 70-kDa Heat Shock Protein in human cells exposed to electromagnetic fields. 82
Induzione differenziale da ipertonicità delle attività di trasporto dei sistemi A e BGT-1 in cellule endoteliali 82
Evaluation of gefitinib maintenance in an EGFR-mutant NSCLC cell line with acquired resistance 81
Hyperosmotic stress response 81
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti 80
Proteasome inhibition restores accumulation of HSP72 and HuR proteins in human fibroblasts aged in vitro 78
Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro 77
Evaluation of gefitinib maintenance in an EGFR-mutant NSCL cell line with acquired resistance 74
New therapeutic strategies for malignant pleural mesothelioma 73
Proteasome inhibition during heat shock restores synthesis and accumulation of HSP72 protein in human fibroblasts aged in vitro. 72
Totale 12.369
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Categoria #
all - tutte 45.779
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.779
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021475 0 0 0 0 0 14 74 31 133 24 162 37
2021/2022560 30 19 27 47 19 10 86 61 31 38 37 155
2022/20232.062 222 200 133 130 235 229 17 114 658 7 91 26
2023/2024880 38 62 30 39 66 186 64 66 36 51 95 147
2024/20252.729 93 146 173 185 239 284 173 138 340 236 257 465
2025/20263.555 491 560 786 579 851 288 0 0 0 0 0 0
Totale 13.139