IRIS
BONELLI, Mara
 Distribuzione geografica
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Continente #
NA - Nord America 5.710
AS - Asia 4.692
EU - Europa 3.880
SA - Sud America 661
AF - Africa 257
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 1
Totale 15.212
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Nazione #
US - Stati Uniti d'America 5.594
SG - Singapore 1.587
CN - Cina 1.390
IT - Italia 891
VN - Vietnam 767
IE - Irlanda 545
FI - Finlandia 539
BR - Brasile 518
SE - Svezia 481
DE - Germania 398
HK - Hong Kong 329
UA - Ucraina 266
FR - Francia 181
ZA - Sudafrica 157
NL - Olanda 138
TR - Turchia 129
GB - Regno Unito 120
IN - India 118
RU - Federazione Russa 102
CA - Canada 71
BD - Bangladesh 68
BE - Belgio 58
AR - Argentina 56
AT - Austria 46
CI - Costa d'Avorio 40
IQ - Iraq 34
KR - Corea 34
JP - Giappone 30
PL - Polonia 30
ID - Indonesia 29
MX - Messico 27
EC - Ecuador 24
CO - Colombia 23
ES - Italia 23
PK - Pakistan 21
PH - Filippine 19
MA - Marocco 17
TH - Thailandia 14
CZ - Repubblica Ceca 13
SA - Arabia Saudita 13
VE - Venezuela 11
IR - Iran 10
JO - Giordania 10
KE - Kenya 10
LT - Lituania 10
UZ - Uzbekistan 10
EG - Egitto 9
PY - Paraguay 9
MY - Malesia 8
AU - Australia 7
AL - Albania 6
AZ - Azerbaigian 6
KG - Kirghizistan 6
OM - Oman 6
PS - Palestinian Territory 6
RO - Romania 6
TN - Tunisia 6
TW - Taiwan 6
CL - Cile 5
GE - Georgia 5
HU - Ungheria 5
NP - Nepal 5
PE - Perù 5
SY - Repubblica araba siriana 5
UY - Uruguay 5
BO - Bolivia 4
DZ - Algeria 4
JM - Giamaica 4
LB - Libano 4
LU - Lussemburgo 4
MD - Moldavia 4
NZ - Nuova Zelanda 4
PA - Panama 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
ET - Etiopia 3
KZ - Kazakistan 3
QA - Qatar 3
SN - Senegal 3
AM - Armenia 2
BB - Barbados 2
BG - Bulgaria 2
BW - Botswana 2
CY - Cipro 2
GA - Gabon 2
HN - Honduras 2
IL - Israele 2
LA - Repubblica Popolare Democratica del Laos 2
PT - Portogallo 2
AD - Andorra 1
AO - Angola 1
BH - Bahrain 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
HR - Croazia 1
KH - Cambogia 1
KW - Kuwait 1
Totale 15.198
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Città #
Singapore 802
Dallas 573
Ashburn 558
Dublin 544
San Jose 504
Chandler 480
Ann Arbor 368
Beijing 330
Santa Clara 317
Hong Kong 310
Jacksonville 291
Parma 249
Ho Chi Minh City 238
Dearborn 192
Boardman 168
Hanoi 155
Johannesburg 149
Nanjing 130
Los Angeles 129
New York 114
Izmir 110
Lauterbourg 102
Shanghai 102
Princeton 98
Bremen 97
Hefei 97
Munich 87
San Mateo 86
Milan 83
Chicago 62
Wilmington 60
São Paulo 55
Council Bluffs 51
Helsinki 48
Woodbridge 47
Moscow 46
Nanchang 43
Shenyang 42
Abidjan 40
Brussels 40
Buffalo 38
Haiphong 38
Kunming 38
Toronto 38
Vienna 38
Hebei 36
Jinan 35
Bologna 32
Des Moines 32
Modena 30
Columbus 28
Pune 28
Da Nang 27
The Dalles 27
Tianjin 27
Marseille 26
Frankfurt am Main 25
Houston 25
Seattle 25
Warsaw 24
Changsha 22
Jiaxing 22
Redmond 22
Seoul 22
Stockholm 22
Tokyo 22
Denver 21
Jakarta 21
London 21
Turku 21
Guangzhou 19
Norwalk 18
Rome 18
Nuremberg 17
Rio de Janeiro 17
Manchester 16
Phoenix 16
Leawood 14
Montreal 14
Orem 14
Amsterdam 13
Baghdad 13
Bari 13
Brooklyn 13
Dhaka 13
New Delhi 13
Reggio Emilia 13
Atlanta 12
Belo Horizonte 12
Brasília 12
Brescia 12
Chennai 12
Fremont 12
Wayne 12
Biên Hòa 11
Hangzhou 11
Hải Dương 11
Boston 10
Poplar 10
San Francisco 10
Totale 9.231
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Nome #
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 350
Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines 262
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 246
PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC) 243
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models 241
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 213
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 210
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 200
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 196
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC 195
CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells 191
Characterization of gefitinib uptake in NSCLC cell lines 190
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 189
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance 185
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 185
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method 184
Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung 184
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis 182
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments 182
Anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM-1 breast cancer cells 181
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress 179
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation 178
Anti-proliferative effect of combining Letrozole with Sorafenib in MCF-7/Arom-1 breast cancer cells 177
5-benzylidene-hydantoin UPR 1024 acts as EGFR inhibitor and induces DNA damage in A549 NSCLC cell line 177
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification 177
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines 176
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations. 174
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer 174
Corrigendum: CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells (Frontiers in Oncology, (2022), 12, (942341), 10.3389/fonc.2022.942341) 170
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines 169
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 169
Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines 168
Attenuated expression of 70kDa heat shock protein in WI-38 human fibroblasts during aging in vitro 166
Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations 163
CDK4/6 INHIBITORS AS A NEW THERAPEUTIC APPROACH IN MESOTHELIOMA MODELS 160
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines 160
Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity 160
Attenuata induzione del gene SNAT-2 in fibroblasti umani senescenti esposti a stress iperosmolare 158
Effects of FGFR1 inhibition on survival, proliferation, and energy metabolism in Non Small Cell Lung Cancer (NSCLC) cell lines 158
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 158
Meccanismo d’azione di UPR 1024: un nuovo farmaco con attività antiproliferativa in cellule di carcinoma polmonare umano 157
Anti-proliferative and pro-apoptotic effects of Sorafenib in breast cancer cells in vitro. 157
Anti-proliferative and pro-apoptotic effects of soarfenib in MCF-7/AROM-1 breast cancer cells. 148
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines 146
Osmotic regulation of ATA2 mRNA expression and amino acid transport system A activity 146
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. (Cavazzoni and Bonelli co-first authors) 146
Alterazioni della degradazione proteasoma-dipendente nel corso dell'invecchiamento ed effetti delle restrizioni caloriche 145
Alterazioni della degradazione proteasoma-dipendente nel corso dell’invecchiamento ed effetti delle restrizioni caloriche 145
New treatment opportunities in phosphatase and tensin homolo(PTen)-deficient tumors: Focus on PTen/focal adhesion kinase pathway 139
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 136
Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells 132
Attenuata induzione del gene snat2 in fibroblasti umani senescenti sottoposti a stress iperosmolare 132
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 132
Synergistic activity of letrozole and sorafenib on breast cancer cells 131
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 131
Hypertonic stress and amino acid deprivation both increase expression of mRNA for amino acid transport system A 128
Synergistic activity of letrozole and sorafenib on MCF7/AROM-1 breast cancer cells 128
Multiple effects of CDK4/6 inhibition in cancer: From cell cycle arrest to immunomodulation 127
Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines 125
The effect of heat shock on amino acid transport and cell volume in 3T3 cells 123
Induzione di sistemi di trasporto in condizioni di stress ipertonico 122
Correction to: Pemetrexed Enhances Membrane PD-L1 Expression and Potentiates T Cell-Mediated Cytotoxicity by Anti-PD-L1 Antibody Therapy in Non-Small-Cell Lung Cancer (Cancers, (2020), 12, 3, (666), 10.3390/cancers12030666) 120
Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity 120
Targeting oncogenic PI3K/Akt/mTOR pathway in squamous cell lung carcinoma 120
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 117
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones 117
Induzione di osmotolleranza in cellule endoteliali derivate da arteria polmonare 116
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis 116
Immunotherapeutic approaches in malignant pleural mesothelioma 115
Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts 113
Correction to: The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells (Journal of Experimental & Clinical Cancer Research, (2018), 37, 1, (72), 10.1186/s13046-018-0741-3) 111
L’inibizione proteasomica ripristina in cellule senescenti l’espressione di HSP70 110
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines 110
Hyperosmotic stress response 108
Effect of proteasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 106
Espressione Inducibile del gene FHIT in cellule di carcinoma polmonare 104
Inhibition of Human Malignant Pleural Mesothelioma Growth by Mesenchymal Stromal Cells 104
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines 104
Increased level of 70-kDa Heat Shock Protein in human cells exposed to electromagnetic fields. 103
Overcoming resistance of EGFR tyrosine kinase inhibitors by new cytostatic and proapoptotic drugs in non small cell lung cancer cell lines 103
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti. 101
Risposta adattativa di cellule endoteliali a stress iperosmolare 100
Synergic anti-proliferative effect of gefitinib and RAD001 in non small cell lung cancer cell lines 100
Effect of letrozole and sorafenib on cell proliferation and apoptosis of MCF-7/AROM-1 breast cancer cell line 99
Targeting FGFR1 pathway in squamous cell lung cancer 97
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer 96
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti 95
Increased level of inducible HSP70 in cells exposed to electromagnetic fields. 95
Effect of protesasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 94
Erlotinib potentiates Cetuximab-dependent call citotoxicity in EGFR wild type NSCLC cell lines 93
Induzione differenziale da ipertonicità delle attività di trasporto dei sistemi A e BGT-1 in cellule endoteliali 92
Hyperosmotic stress response 92
L'inibizione dell'attività proteasomica ripristina la capacità dei fibroblasti umani senescenti di rispondere allo shock termico 92
Shiga toxin 1 and ricin inhibit thr repair of H2O2-induced DNA single strand breks in cultured mammalian cells 91
Proteasome inhibition restores accumulation of HSP72 and HuR proteins in human fibroblasts aged in vitro 91
Effetto dell’inibizione proteasomica sull’espressione del gene HSP70 in cellule senescenti. 90
Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro 90
Evaluation of gefitinib maintenance in an EGFR-mutant NSCLC cell line with acquired resistance 90
Intrinsic Resistance to Osimertinib in EGFR Mutated NSCLC Cell Lines Induced by Alteration in Cell-Cycle Regulators 89
Pure anti-tumor effect of zoledronic acid in naive bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy" 89
Totale 14.449
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Categoria #
all - tutte 50.122
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.122
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021199 0 0 0 0 0 0 0 0 0 0 162 37
2021/2022560 30 19 27 47 19 10 86 61 31 38 37 155
2022/20232.062 222 200 133 130 235 229 17 114 658 7 91 26
2023/2024880 38 62 30 39 66 186 64 66 36 51 95 147
2024/20252.729 93 146 173 185 239 284 173 138 340 236 257 465
2025/20265.806 491 560 786 579 851 314 667 194 820 403 141 0
Totale 15.390