IRIS
BONELLI, Mara
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 2.777
EU - Europa 2.739
AS - Asia 1.013
OC - Oceania 2
SA - Sud America 1
Totale 6.532
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 2.748
CN - Cina 794
IE - Irlanda 553
IT - Italia 514
FI - Finlandia 505
SE - Svezia 466
DE - Germania 263
UA - Ucraina 257
TR - Turchia 110
BE - Belgio 49
IN - India 49
GB - Regno Unito 43
CA - Canada 29
AT - Austria 28
SG - Singapore 27
FR - Francia 23
NL - Olanda 13
HK - Hong Kong 10
IR - Iran 8
VN - Vietnam 8
CZ - Repubblica Ceca 5
JP - Giappone 5
RO - Romania 4
CH - Svizzera 3
HU - Ungheria 3
PL - Polonia 3
RU - Federazione Russa 3
LU - Lussemburgo 2
NZ - Nuova Zelanda 2
HR - Croazia 1
KR - Corea 1
PE - Perù 1
PK - Pakistan 1
SI - Slovenia 1
Totale 6.532
Salva come PNG Salva come JPEG
Città #
Dublin 553
Chandler 496
Ann Arbor 368
Jacksonville 291
Dearborn 192
Beijing 170
Parma 146
Ashburn 138
Nanjing 128
Izmir 110
Bremen 98
Princeton 98
San Mateo 86
Shanghai 69
New York 64
Wilmington 60
Boardman 47
Woodbridge 47
Hefei 42
Nanchang 42
Shenyang 42
Kunming 38
Hebei 36
Helsinki 35
Jinan 33
Brussels 31
Des Moines 31
Milan 29
Pune 28
Vienna 28
Los Angeles 27
Toronto 25
Tianjin 23
Modena 22
Redmond 22
Jiaxing 21
Seattle 20
Houston 18
Norwalk 18
Changsha 16
Guangzhou 14
Leawood 14
Fremont 12
Wayne 12
Hangzhou 10
Hong Kong 10
Rome 10
Amsterdam 8
Ardabil 8
Augusta 8
Dong Ket 8
Fuzhou 8
Grafing 8
Taiyuan 8
Binche 7
Leuven 7
Auburn Hills 6
Chengdu 6
Follonica 6
Monmouth Junction 6
Ningbo 6
Reggio Emilia 6
Salsomaggiore Terme 6
Zhengzhou 6
Borås 5
Lanzhou 5
Mumbai 5
Redwood City 5
Bologna 4
Düsseldorf 4
Fairfield 4
Huizen 4
Mestre 4
Mons 4
Neviano degli Arduini 4
Phoenix 4
Rockville 4
Soliera 4
Xian 4
Albano Laziale 3
Bari 3
Bergamo 3
Brescia 3
Como 3
Cuneo 3
Florence 3
Frankfurt am Main 3
Gainesville 3
Genoa 3
Haikou 3
Kraków 3
London 3
Múggia 3
Prata Di Pordenone 3
Reggio Nell'emilia 3
Rubiera 3
Savignano sul Rubicone 3
Shaoxing 3
Singapore 3
Taizhou 3
Totale 4.115
Salva come PNG Salva come JPEG
Nome #
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 194
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC 120
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 115
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance 99
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 99
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 99
Characterization of gefitinib uptake in NSCLC cell lines 97
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis 95
Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity 93
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations. 92
Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung 91
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method 88
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 87
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 87
Osmotic regulation of ATA2 mRNA expression and amino acid transport system A activity 87
Anti-proliferative effect of combining Letrozole with Sorafenib in MCF-7/Arom-1 breast cancer cells 84
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification 83
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines 82
Attenuated expression of 70kDa heat shock protein in WI-38 human fibroblasts during aging in vitro 80
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines 80
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines 80
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 80
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation 79
Anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM-1 breast cancer cells 79
Meccanismo d’azione di UPR 1024: un nuovo farmaco con attività antiproliferativa in cellule di carcinoma polmonare umano 78
Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines 78
Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells 76
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer 76
New treatment opportunities in phosphatase and tensin homolo(PTen)-deficient tumors: Focus on PTen/focal adhesion kinase pathway 75
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. (Cavazzoni and Bonelli co-first authors) 75
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress 73
The effect of heat shock on amino acid transport and cell volume in 3T3 cells 72
Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations 72
Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity 71
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 71
Induzione di sistemi di trasporto in condizioni di stress ipertonico 70
Attenuata induzione del gene SNAT-2 in fibroblasti umani senescenti esposti a stress iperosmolare 69
Hypertonic stress and amino acid deprivation both increase expression of mRNA for amino acid transport system A 69
Synergistic activity of letrozole and sorafenib on MCF7/AROM-1 breast cancer cells 69
Anti-proliferative and pro-apoptotic effects of Sorafenib in breast cancer cells in vitro. 69
Alterazioni della degradazione proteasoma-dipendente nel corso dell'invecchiamento ed effetti delle restrizioni caloriche 68
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines 68
5-benzylidene-hydantoin UPR 1024 acts as EGFR inhibitor and induces DNA damage in A549 NSCLC cell line 68
Induzione di osmotolleranza in cellule endoteliali derivate da arteria polmonare 67
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 67
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 66
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis 65
Multiple effects of CDK4/6 inhibition in cancer: From cell cycle arrest to immunomodulation 65
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 63
Alterazioni della degradazione proteasoma-dipendente nel corso dell’invecchiamento ed effetti delle restrizioni caloriche 62
Anti-proliferative and pro-apoptotic effects of soarfenib in MCF-7/AROM-1 breast cancer cells. 61
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 59
Effect of proteasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 58
Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines 58
L'inibizione dell'attività proteasomica ripristina la capacità dei fibroblasti umani senescenti di rispondere allo shock termico 58
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 58
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones 57
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 56
Increased level of inducible HSP70 in cells exposed to electromagnetic fields. 56
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti. 55
Effects of FGFR1 inhibition on survival, proliferation, and energy metabolism in Non Small Cell Lung Cancer (NSCLC) cell lines 55
Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts 54
Risposta adattativa di cellule endoteliali a stress iperosmolare 53
Overcoming resistance of EGFR tyrosine kinase inhibitors by new cytostatic and proapoptotic drugs in non small cell lung cancer cell lines 53
CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells 52
Attenuata induzione del gene snat2 in fibroblasti umani senescenti sottoposti a stress iperosmolare 52
Erlotinib potentiates Cetuximab-dependent call citotoxicity in EGFR wild type NSCLC cell lines 51
Effetto dell’inibizione proteasomica sull’espressione del gene HSP70 in cellule senescenti. 50
Effect of letrozole and sorafenib on cell proliferation and apoptosis of MCF-7/AROM-1 breast cancer cell line 50
Synergistic activity of letrozole and sorafenib on breast cancer cells 50
Targeting oncogenic PI3K/Akt/mTOR pathway in squamous cell lung carcinoma 50
Synergic anti-proliferative effect of gefitinib and RAD001 in non small cell lung cancer cell lines 50
Evaluation of gefitinib maintenance in an EGFR-mutant NSCLC cell line with acquired resistance 49
CDK4/6 INHIBITORS AS A NEW THERAPEUTIC APPROACH IN MESOTHELIOMA MODELS 48
Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro 48
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer 48
Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK-mTORC1 signaling 48
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines 48
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti 47
Espressione Inducibile del gene FHIT in cellule di carcinoma polmonare 47
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines 47
L’inibizione proteasomica ripristina in cellule senescenti l’espressione di HSP70 46
Effect of protesasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 46
Induzione differenziale da ipertonicità delle attività di trasporto dei sistemi A e BGT-1 in cellule endoteliali 45
Low-level caloric restriction rescues proteasome activity and hsc70 level in liver of aged rats 44
Hyperosmotic stress response 44
Shiga toxin 1 and ricin inhibit thr repair of H2O2-induced DNA single strand breks in cultured mammalian cells 44
Proteasome inhibition restores accumulation of HSP72 and HuR proteins in human fibroblasts aged in vitro 44
Hyperosmotic stress response 44
Erlotinib potentiates Cetuximab-dependent cell citotoxicity in EGFR wild-type NSCLC cell lines 44
Immunotherapeutic approaches in malignant pleural mesothelioma 43
Increased level of 70-kDa Heat Shock Protein in human cells exposed to electromagnetic fields. 42
Pure anti-tumor effect of zoledronic acid in naive bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy" 40
Targeting FGFR1 pathway in squamous cell lung cancer 39
Synergic anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM breast cancer cells 39
Evaluation of gefitinib maintenance in an EGFR-mutant NSCL cell line with acquired resistance 39
Proteasome inhibition during heat shock restores synthesis and accumulation of HSP72 protein in human fibroblasts aged in vitro. 38
New therapeutic strategies for malignant pleural mesothelioma 38
Sensibilità di cellule di carcinoma polmonare umano al trattamento con farmaci anti-EGFR. 37
Meccanismi cellulari e molecolari coinvolti nella risposta di adattamento di cellule endoteliali all’ ipertonicità 37
Totale 6.511
Salva come PNG Salva come JPEG
Categoria #
all - tutte 21.143
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.143
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019144 0 0 0 0 0 0 0 0 0 0 137 7
2019/20201.425 209 239 77 19 95 152 201 55 119 112 53 94
2020/2021752 13 77 62 37 88 14 74 31 133 24 162 37
2021/2022560 30 19 27 47 19 10 86 61 31 38 37 155
2022/20232.100 222 205 136 141 236 233 17 115 671 7 91 26
2023/2024683 38 64 31 39 67 187 65 70 36 51 35 0
Totale 6.696