IRIS
BONELLI, Mara
 Distribuzione geografica
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Continente #
EU - Europa 2682
NA - Nord America 2320
AS - Asia 846
OC - Oceania 1
Totale 5849
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Nazione #
US - Stati Uniti d'America 2293
CN - Cina 693
IE - Irlanda 636
FI - Finlandia 503
SE - Svezia 466
IT - Italia 398
DE - Germania 262
UA - Ucraina 257
TR - Turchia 110
BE - Belgio 42
AT - Austria 39
GB - Regno Unito 33
CA - Canada 27
IN - India 21
FR - Francia 19
IR - Iran 8
VN - Vietnam 8
CZ - Repubblica Ceca 5
JP - Giappone 5
NL - Olanda 5
RO - Romania 4
HU - Ungheria 3
PL - Polonia 3
RU - Federazione Russa 3
CH - Svizzera 2
LU - Lussemburgo 1
NZ - Nuova Zelanda 1
SG - Singapore 1
SI - Slovenia 1
Totale 5849
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Città #
Dublin 636
Chandler 496
Ann Arbor 368
Jacksonville 291
Dearborn 192
Beijing 166
Nanjing 128
Parma 123
Izmir 110
Bremen 98
Princeton 98
San Mateo 86
Wilmington 60
Woodbridge 47
Hefei 42
Nanchang 42
Shenyang 42
Kunming 38
Hebei 36
Vienna 36
Brussels 35
Helsinki 34
Jinan 33
Des Moines 31
Toronto 25
Tianjin 23
Redmond 22
Jiaxing 21
Modena 21
Houston 18
Norwalk 18
Boardman 17
Changsha 16
Los Angeles 15
Guangzhou 14
Leawood 14
Milan 14
Fremont 12
Wayne 12
Hangzhou 10
Ardabil 8
Augusta 8
Dong Ket 8
Fuzhou 8
Grafing 8
Taiyuan 8
Leuven 7
Seattle 7
Auburn Hills 6
Chengdu 6
Follonica 6
Monmouth Junction 6
Ningbo 6
Zhengzhou 6
Borås 5
Lanzhou 5
Mumbai 5
Redwood City 5
Ashburn 4
Düsseldorf 4
Fairfield 4
Huizen 4
Mestre 4
Rockville 4
Rome 4
Soliera 4
Xian 4
Bergamo 3
Como 3
Gainesville 3
Haikou 3
Kraków 3
Múggia 3
Prata Di Pordenone 3
Reggio Nell'emilia 3
Rubiera 3
Shaoxing 3
Taizhou 3
Trento 3
Wenzhou 3
Bari 2
Brescia 2
Carpenedolo 2
Casalgrande 2
Caserta 2
Chongqing 2
Falls Church 2
Frankfurt am Main 2
Geislingen an der Steige 2
Hanover 2
Iseo 2
Montegaldella 2
Mountain View 2
Napoli 2
Neviano degli Arduini 2
New Delhi 2
Pavia 2
Pesaro 2
Philadelphia 2
Phoenix 2
Totale 3773
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Nome #
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 183
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC 118
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 105
Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity 93
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations. 90
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance 89
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 88
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis 87
Characterization of gefitinib uptake in NSCLC cell lines 87
Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung 85
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method 83
Osmotic regulation of ATA2 mRNA expression and amino acid transport system A activity 83
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines 79
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 78
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 76
Anti-proliferative effect of combining Letrozole with Sorafenib in MCF-7/Arom-1 breast cancer cells 74
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification 74
Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells 73
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines 73
Meccanismo d’azione di UPR 1024: un nuovo farmaco con attività antiproliferativa in cellule di carcinoma polmonare umano 72
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines 71
Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations 71
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 71
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 70
Anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM-1 breast cancer cells 70
Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity 69
Induzione di sistemi di trasporto in condizioni di stress ipertonico 69
New treatment opportunities in phosphatase and tensin homolo(PTen)-deficient tumors: Focus on PTen/focal adhesion kinase pathway 69
Hypertonic stress and amino acid deprivation both increase expression of mRNA for amino acid transport system A 69
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. (Cavazzoni and Bonelli co-first authors) 69
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation 68
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer 67
Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines 67
Attenuated expression of 70kDa heat shock protein in WI-38 human fibroblasts during aging in vitro 66
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress 66
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis 66
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 65
Induzione di osmotolleranza in cellule endoteliali derivate da arteria polmonare 64
Attenuata induzione del gene SNAT-2 in fibroblasti umani senescenti esposti a stress iperosmolare 63
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines 63
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 63
Anti-proliferative and pro-apoptotic effects of Sorafenib in breast cancer cells in vitro. 62
The effect of heat shock on amino acid transport and cell volume in 3T3 cells 61
Synergistic activity of letrozole and sorafenib on MCF7/AROM-1 breast cancer cells 60
Multiple effects of CDK4/6 inhibition in cancer: From cell cycle arrest to immunomodulation 60
Alterazioni della degradazione proteasoma-dipendente nel corso dell'invecchiamento ed effetti delle restrizioni caloriche 59
5-benzylidene-hydantoin UPR 1024 acts as EGFR inhibitor and induces DNA damage in A549 NSCLC cell line 59
L'inibizione dell'attività proteasomica ripristina la capacità dei fibroblasti umani senescenti di rispondere allo shock termico 57
Effect of proteasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 56
Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines 56
Increased level of inducible HSP70 in cells exposed to electromagnetic fields. 56
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 55
Alterazioni della degradazione proteasoma-dipendente nel corso dell’invecchiamento ed effetti delle restrizioni caloriche 55
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones 55
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 55
Risposta adattativa di cellule endoteliali a stress iperosmolare 54
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti. 53
Anti-proliferative and pro-apoptotic effects of soarfenib in MCF-7/AROM-1 breast cancer cells. 52
Effect of letrozole and sorafenib on cell proliferation and apoptosis of MCF-7/AROM-1 breast cancer cell line 52
Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts 52
Overcoming resistance of EGFR tyrosine kinase inhibitors by new cytostatic and proapoptotic drugs in non small cell lung cancer cell lines 51
Synergic anti-proliferative effect of gefitinib and RAD001 in non small cell lung cancer cell lines 50
Erlotinib potentiates Cetuximab-dependent call citotoxicity in EGFR wild type NSCLC cell lines 50
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 50
Synergistic activity of letrozole and sorafenib on breast cancer cells 49
Effects of FGFR1 inhibition on survival, proliferation, and energy metabolism in Non Small Cell Lung Cancer (NSCLC) cell lines 49
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines 49
Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro 48
Evaluation of gefitinib maintenance in an EGFR-mutant NSCLC cell line with acquired resistance 48
Effetto dell’inibizione proteasomica sull’espressione del gene HSP70 in cellule senescenti. 46
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 46
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines 46
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer 45
Espressione Inducibile del gene FHIT in cellule di carcinoma polmonare 45
Induzione differenziale da ipertonicità delle attività di trasporto dei sistemi A e BGT-1 in cellule endoteliali 44
Targeting oncogenic PI3K/Akt/mTOR pathway in squamous cell lung carcinoma 44
L’inibizione proteasomica ripristina in cellule senescenti l’espressione di HSP70 43
Shiga toxin 1 and ricin inhibit thr repair of H2O2-induced DNA single strand breks in cultured mammalian cells 43
Proteasome inhibition restores accumulation of HSP72 and HuR proteins in human fibroblasts aged in vitro 42
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti 41
Effect of protesasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 41
Attenuata induzione del gene snat2 in fibroblasti umani senescenti sottoposti a stress iperosmolare 41
Hyperosmotic stress response 41
Erlotinib potentiates Cetuximab-dependent cell citotoxicity in EGFR wild-type NSCLC cell lines 41
Hyperosmotic stress response 40
Evaluation of gefitinib maintenance in an EGFR-mutant NSCL cell line with acquired resistance 40
Increased level of 70-kDa Heat Shock Protein in human cells exposed to electromagnetic fields. 39
Low-level caloric restriction rescues proteasome activity and hsc70 level in liver of aged rats 39
Proteasome inhibition during heat shock restores synthesis and accumulation of HSP72 protein in human fibroblasts aged in vitro. 38
Effects of sorafenib on energy metabolism in breast cancer cells: role of AMPK-mTORC1 signaling 38
Immunotherapeutic approaches in malignant pleural mesothelioma 38
Pure anti-tumor effect of zoledronic acid in naive bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy" 37
New therapeutic strategies for malignant pleural mesothelioma 37
Targeting FGFR1 pathway in squamous cell lung cancer 36
Synergic anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM breast cancer cells 36
Sensibilità di cellule di carcinoma polmonare umano al trattamento con farmaci anti-EGFR. 35
Meccanismi cellulari e molecolari coinvolti nella risposta di adattamento di cellule endoteliali all’ ipertonicità 35
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 34
Espressione di HuR correla con l'induzione di HSP70 nell'invecchiamento cellulare in vitro 33
null 31
Totale 5954
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Categoria #
all - tutte 10811
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 10811
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/201823 0000 00 00 6935
2018/2019316 41115 2950 297 2791377
2019/20201425 2092397719 95152 20155 1191125394
2020/2021752 13776237 8814 7431 1332416237
2021/2022560 30192747 1910 8661 313837155
2022/20232089 222205136141 236233 35121 760000
Totale 6002