IRIS
BONELLI, Mara
 Distribuzione geografica
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Continente #
NA - Nord America 6.390
AS - Asia 4.822
EU - Europa 4.068
SA - Sud America 705
AF - Africa 262
Continente sconosciuto - Info sul continente non disponibili 185
OC - Oceania 11
Totale 16.443
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Nazione #
US - Stati Uniti d'America 6.247
SG - Singapore 1.595
CN - Cina 1.401
IT - Italia 1.068
VN - Vietnam 770
IE - Irlanda 545
FI - Finlandia 539
BR - Brasile 532
SE - Svezia 481
DE - Germania 398
HK - Hong Kong 331
UA - Ucraina 266
FR - Francia 181
ZA - Sudafrica 157
BD - Bangladesh 150
NL - Olanda 139
TR - Turchia 129
GB - Regno Unito 125
IN - India 120
RU - Federazione Russa 102
CA - Canada 80
AR - Argentina 60
BE - Belgio 58
AT - Austria 46
CI - Costa d'Avorio 41
KR - Corea 35
IQ - Iraq 34
MX - Messico 34
CO - Colombia 33
EC - Ecuador 32
ID - Indonesia 32
PL - Polonia 31
JP - Giappone 30
PH - Filippine 25
ES - Italia 24
PK - Pakistan 23
MA - Marocco 17
SA - Arabia Saudita 17
VE - Venezuela 16
TH - Thailandia 15
CZ - Repubblica Ceca 13
KE - Kenya 12
MY - Malesia 12
IR - Iran 10
JM - Giamaica 10
JO - Giordania 10
LT - Lituania 10
UZ - Uzbekistan 10
EG - Egitto 9
PY - Paraguay 9
AU - Australia 7
RO - Romania 7
AL - Albania 6
AZ - Azerbaigian 6
CL - Cile 6
KG - Kirghizistan 6
MD - Moldavia 6
OM - Oman 6
PS - Palestinian Territory 6
TN - Tunisia 6
TW - Taiwan 6
UY - Uruguay 6
BO - Bolivia 5
GE - Georgia 5
HN - Honduras 5
HU - Ungheria 5
NP - Nepal 5
PE - Perù 5
SY - Repubblica araba siriana 5
DZ - Algeria 4
LB - Libano 4
LU - Lussemburgo 4
NZ - Nuova Zelanda 4
PA - Panama 4
QA - Qatar 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
ET - Etiopia 3
KZ - Kazakistan 3
SN - Senegal 3
AM - Armenia 2
BB - Barbados 2
BG - Bulgaria 2
BW - Botswana 2
CY - Cipro 2
GA - Gabon 2
GT - Guatemala 2
IL - Israele 2
LA - Repubblica Popolare Democratica del Laos 2
PT - Portogallo 2
AD - Andorra 1
AO - Angola 1
BH - Bahrain 1
CG - Congo 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
GR - Grecia 1
GY - Guiana 1
HR - Croazia 1
KH - Cambogia 1
Totale 16.242
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Città #
Singapore 807
San Jose 616
Ashburn 595
Dallas 575
Dublin 544
Chandler 480
Santa Clara 392
Ann Arbor 368
Beijing 335
Hong Kong 311
Jacksonville 293
Parma 263
Council Bluffs 240
Ho Chi Minh City 238
Dearborn 192
Boardman 172
Hanoi 156
Johannesburg 149
Los Angeles 135
Nanjing 130
New York 127
Izmir 110
Shanghai 103
Lauterbourg 102
Milan 101
Princeton 98
Bremen 97
Hefei 97
Munich 87
San Mateo 86
Chicago 75
Wilmington 60
São Paulo 55
Helsinki 48
Bologna 47
Woodbridge 47
Buffalo 46
Moscow 46
Modena 44
Nanchang 43
Shenyang 42
Abidjan 41
Toronto 41
Brussels 40
Haiphong 38
Kunming 38
Vienna 38
Hebei 36
Jinan 35
Des Moines 32
Rome 32
Houston 30
Columbus 28
Da Nang 28
Pune 28
Seattle 27
The Dalles 27
Tianjin 27
Marseille 26
Frankfurt am Main 25
Warsaw 25
Phoenix 24
Seoul 23
Changsha 22
Jiaxing 22
Redmond 22
Stockholm 22
Tokyo 22
Denver 21
Jakarta 21
London 21
Turku 21
Guangzhou 19
Norwalk 18
Reggio Emilia 18
Rio de Janeiro 18
Levanto 17
Manchester 17
Nuremberg 17
Orem 16
Bari 14
Brooklyn 14
Leawood 14
Montreal 14
Amsterdam 13
Baghdad 13
Belo Horizonte 13
Brescia 13
Dhaka 13
New Delhi 13
Atlanta 12
Bogotá 12
Boston 12
Brasília 12
Chennai 12
Fremont 12
Wayne 12
Biên Hòa 11
Hangzhou 11
Hải Dương 11
Totale 9.826
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Nome #
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 358
Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines 287
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 260
PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC) 258
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models 253
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 227
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 222
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 219
CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells 216
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 216
Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung 212
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 208
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC 202
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments 202
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance 200
Characterization of gefitinib uptake in NSCLC cell lines 197
Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines 196
Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity 194
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress 193
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 189
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis 188
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method 187
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation 187
Anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM-1 breast cancer cells 187
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification 185
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines 183
5-benzylidene-hydantoin UPR 1024 acts as EGFR inhibitor and induces DNA damage in A549 NSCLC cell line 183
Anti-proliferative effect of combining Letrozole with Sorafenib in MCF-7/Arom-1 breast cancer cells 182
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer 181
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines 179
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations. 178
Corrigendum: CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells (Frontiers in Oncology, (2022), 12, (942341), 10.3389/fonc.2022.942341) 178
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 177
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines 172
Attenuated expression of 70kDa heat shock protein in WI-38 human fibroblasts during aging in vitro 171
CDK4/6 INHIBITORS AS A NEW THERAPEUTIC APPROACH IN MESOTHELIOMA MODELS 170
Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations 166
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 166
Meccanismo d’azione di UPR 1024: un nuovo farmaco con attività antiproliferativa in cellule di carcinoma polmonare umano 163
Attenuata induzione del gene SNAT-2 in fibroblasti umani senescenti esposti a stress iperosmolare 163
Effects of FGFR1 inhibition on survival, proliferation, and energy metabolism in Non Small Cell Lung Cancer (NSCLC) cell lines 162
Anti-proliferative and pro-apoptotic effects of Sorafenib in breast cancer cells in vitro. 161
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines 156
Synergistic activity of letrozole and sorafenib on breast cancer cells 153
Anti-proliferative and pro-apoptotic effects of soarfenib in MCF-7/AROM-1 breast cancer cells. 152
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. (Cavazzoni and Bonelli co-first authors) 152
Alterazioni della degradazione proteasoma-dipendente nel corso dell’invecchiamento ed effetti delle restrizioni caloriche 151
Osmotic regulation of ATA2 mRNA expression and amino acid transport system A activity 150
Alterazioni della degradazione proteasoma-dipendente nel corso dell'invecchiamento ed effetti delle restrizioni caloriche 149
Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells 148
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 144
New treatment opportunities in phosphatase and tensin homolo(PTen)-deficient tumors: Focus on PTen/focal adhesion kinase pathway 143
Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines 141
Immunotherapeutic approaches in malignant pleural mesothelioma 141
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 139
Correction to: Pemetrexed Enhances Membrane PD-L1 Expression and Potentiates T Cell-Mediated Cytotoxicity by Anti-PD-L1 Antibody Therapy in Non-Small-Cell Lung Cancer (Cancers, (2020), 12, 3, (666), 10.3390/cancers12030666) 137
Attenuata induzione del gene snat2 in fibroblasti umani senescenti sottoposti a stress iperosmolare 136
Multiple effects of CDK4/6 inhibition in cancer: From cell cycle arrest to immunomodulation 136
Induzione di sistemi di trasporto in condizioni di stress ipertonico 134
Hypertonic stress and amino acid deprivation both increase expression of mRNA for amino acid transport system A 134
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 134
Synergistic activity of letrozole and sorafenib on MCF7/AROM-1 breast cancer cells 133
The effect of heat shock on amino acid transport and cell volume in 3T3 cells 132
null 126
Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity 126
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones 124
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 123
Targeting oncogenic PI3K/Akt/mTOR pathway in squamous cell lung carcinoma 122
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis 120
Induzione di osmotolleranza in cellule endoteliali derivate da arteria polmonare 119
Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts 118
L’inibizione proteasomica ripristina in cellule senescenti l’espressione di HSP70 115
Hyperosmotic stress response 115
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines 115
Pure anti-tumor effect of zoledronic acid in naive bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy" 114
Effect of proteasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 111
Inhibition of Human Malignant Pleural Mesothelioma Growth by Mesenchymal Stromal Cells 111
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines 108
Increased level of 70-kDa Heat Shock Protein in human cells exposed to electromagnetic fields. 107
Overcoming resistance of EGFR tyrosine kinase inhibitors by new cytostatic and proapoptotic drugs in non small cell lung cancer cell lines 105
Espressione Inducibile del gene FHIT in cellule di carcinoma polmonare 105
Synergic anti-proliferative effect of gefitinib and RAD001 in non small cell lung cancer cell lines 105
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti. 104
Targeting FGFR1 pathway in squamous cell lung cancer 103
Increased level of inducible HSP70 in cells exposed to electromagnetic fields. 103
Intrinsic Resistance to Osimertinib in EGFR Mutated NSCLC Cell Lines Induced by Alteration in Cell-Cycle Regulators 102
Risposta adattativa di cellule endoteliali a stress iperosmolare 102
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer 102
Effect of letrozole and sorafenib on cell proliferation and apoptosis of MCF-7/AROM-1 breast cancer cell line 100
Effect of protesasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 99
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti 98
Evaluation of gefitinib maintenance in an EGFR-mutant NSCLC cell line with acquired resistance 98
Shiga toxin 1 and ricin inhibit thr repair of H2O2-induced DNA single strand breks in cultured mammalian cells 98
Proteasome inhibition restores accumulation of HSP72 and HuR proteins in human fibroblasts aged in vitro 97
Induzione differenziale da ipertonicità delle attività di trasporto dei sistemi A e BGT-1 in cellule endoteliali 96
Erlotinib potentiates Cetuximab-dependent call citotoxicity in EGFR wild type NSCLC cell lines 95
L'inibizione dell'attività proteasomica ripristina la capacità dei fibroblasti umani senescenti di rispondere allo shock termico 94
Hyperosmotic stress response 93
Effetto dell’inibizione proteasomica sull’espressione del gene HSP70 in cellule senescenti. 92
Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro 92
Totale 15.330
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Categoria #
all - tutte 55.672
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.672
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022511 0 0 27 47 19 10 86 61 31 38 37 155
2022/20232.062 222 200 133 130 235 229 17 114 658 7 91 26
2023/2024880 38 62 30 39 66 186 64 66 36 51 95 147
2024/20252.729 93 146 173 185 239 284 173 138 340 236 257 465
2025/20266.068 491 560 786 579 851 314 667 194 820 403 229 174
2026/2027791 229 337 225 0 0 0 0 0 0 0 0 0
Totale 16.443