IRIS
BONELLI, Mara
 Distribuzione geografica
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Continente #
NA - Nord America 4.767
EU - Europa 3.634
AS - Asia 3.509
SA - Sud America 596
AF - Africa 201
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 1
Totale 12.714
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Nazione #
US - Stati Uniti d'America 4.676
SG - Singapore 1.364
CN - Cina 1.259
IT - Italia 802
IE - Irlanda 542
FI - Finlandia 539
BR - Brasile 487
SE - Svezia 476
DE - Germania 387
UA - Ucraina 266
HK - Hong Kong 260
VN - Vietnam 222
NL - Olanda 134
TR - Turchia 120
ZA - Sudafrica 120
GB - Regno Unito 112
RU - Federazione Russa 101
IN - India 93
FR - Francia 69
CA - Canada 62
BE - Belgio 58
AT - Austria 46
AR - Argentina 43
CI - Costa d'Avorio 40
PL - Polonia 26
BD - Bangladesh 25
ID - Indonesia 23
ES - Italia 21
KR - Corea 21
EC - Ecuador 20
IQ - Iraq 19
MX - Messico 18
JP - Giappone 16
CO - Colombia 14
PK - Pakistan 14
MA - Marocco 13
CZ - Repubblica Ceca 12
IR - Iran 9
LT - Lituania 9
PY - Paraguay 9
UZ - Uzbekistan 9
VE - Venezuela 9
KE - Kenya 8
JO - Giordania 6
KG - Kirghizistan 6
PS - Palestinian Territory 6
TN - Tunisia 6
AL - Albania 5
AZ - Azerbaigian 5
EG - Egitto 5
RO - Romania 5
HU - Ungheria 4
LU - Lussemburgo 4
NP - Nepal 4
NZ - Nuova Zelanda 4
PE - Perù 4
UY - Uruguay 4
AE - Emirati Arabi Uniti 3
CH - Svizzera 3
CL - Cile 3
LB - Libano 3
MD - Moldavia 3
PA - Panama 3
SN - Senegal 3
SY - Repubblica araba siriana 3
AM - Armenia 2
AU - Australia 2
BG - Bulgaria 2
BO - Bolivia 2
BW - Botswana 2
CY - Cipro 2
GE - Georgia 2
HN - Honduras 2
KZ - Kazakistan 2
QA - Qatar 2
SA - Arabia Saudita 2
AD - Andorra 1
AO - Angola 1
BB - Barbados 1
BH - Bahrain 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
HR - Croazia 1
IL - Israele 1
JM - Giamaica 1
KW - Kuwait 1
LK - Sri Lanka 1
LV - Lettonia 1
MY - Malesia 1
NO - Norvegia 1
OM - Oman 1
PT - Portogallo 1
RS - Serbia 1
SI - Slovenia 1
Totale 12.711
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Città #
Singapore 674
Dallas 569
Dublin 542
Chandler 480
Ashburn 447
Ann Arbor 368
Beijing 326
Santa Clara 314
Jacksonville 291
Hong Kong 260
Parma 222
Dearborn 192
Boardman 158
Nanjing 129
Johannesburg 113
Izmir 110
New York 102
Princeton 98
Shanghai 98
Bremen 97
Hefei 97
Los Angeles 95
Munich 87
San Mateo 86
Milan 79
Ho Chi Minh City 75
Wilmington 60
Chicago 51
São Paulo 50
Helsinki 48
Woodbridge 47
Moscow 46
Nanchang 43
Shenyang 42
Abidjan 40
Brussels 40
Hanoi 40
Kunming 38
Vienna 38
Hebei 36
Toronto 35
Jinan 34
Buffalo 33
Des Moines 31
Columbus 28
Pune 28
Tianjin 27
Modena 26
Marseille 25
Seattle 25
Bologna 24
Houston 23
Jiaxing 22
Redmond 22
The Dalles 22
Warsaw 22
Changsha 21
Turku 21
Council Bluffs 20
Jakarta 20
Seoul 20
London 19
Guangzhou 18
Norwalk 18
Nuremberg 17
Rio de Janeiro 17
Stockholm 17
Denver 16
Frankfurt am Main 16
Rome 16
Manchester 15
Phoenix 15
Leawood 14
Amsterdam 13
Haiphong 13
Reggio Emilia 13
Tokyo 13
Belo Horizonte 12
Brasília 12
Brescia 12
Fremont 12
Montreal 12
Wayne 12
Bari 11
Brooklyn 11
Chennai 10
Hangzhou 10
Poplar 10
Augusta 9
Baghdad 9
Campinas 9
Florence 9
San Francisco 9
Taiyuan 9
Verona 9
Zhengzhou 9
Ardabil 8
Boston 8
Dhaka 8
Dong Ket 8
Totale 7.735
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Nome #
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 308
Targeting metabolic adaptive responses induced by glucose starvation inhibits cell proliferation and enhances cell death in osimertinib-resistant non-small cell lung cancer (NSCLC) cell lines 218
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 205
PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC) 203
Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models 201
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 183
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 179
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 177
Third generation EGFR inhibitor osimertinib combined with pemetrexed or cisplatin exerts long-lasting anti-tumor effect in EGFR-mutated pre-clinical models of NSCLC 169
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 163
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 162
Targeting PI3K somatic mutations reduces invasion and EMT in squamous cell carcinoma of the lung 162
Characterization of gefitinib uptake in NSCLC cell lines 161
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance 161
Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis 157
Combination of Gefitinib and Pemetrexed Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation 155
Epidermal growth factor receptor tyrosine kinase inhibitors: current status and future perspectives in the development of novel irreversible inhibitors for the treatment of mutant non-small cell lung cancer 154
Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method 153
Inhibition of PI3K Pathway Reduces Invasiveness and Epithelial-to-Mesenchymal Transition in Squamous Lung Cancer Cell Lines Harboring PIK3CA Gene Alterations. 150
Creatine as a compatible osmolyte in muscle cells exposed to hypertonic stress 147
Effect of specific PI3K/mTOR inhibitors in squamous lung cancer cells carrying PI3K alterations 147
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification 146
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 146
Anti-proliferative effect of combining Letrozole with Sorafenib in MCF-7/Arom-1 breast cancer cells 145
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines 144
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines 143
Anti-proliferative effect of letrozole and sorafenib in MCF-7/AROM-1 breast cancer cells 143
Immunomodulatory effects of antiangiogenic tyrosine kinase inhibitors in renal cell carcinoma models: Impact on following anti-PD-1 treatments 142
Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity 139
Effect of ABCG2/BCRP Expression on Efflux and Uptake of Gefitinib in NSCLC Cell Lines 139
Attenuated expression of 70kDa heat shock protein in WI-38 human fibroblasts during aging in vitro 138
Meccanismo d’azione di UPR 1024: un nuovo farmaco con attività antiproliferativa in cellule di carcinoma polmonare umano 137
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 135
5-benzylidene-hydantoin UPR 1024 acts as EGFR inhibitor and induces DNA damage in A549 NSCLC cell line 135
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 135
Attenuata induzione del gene SNAT-2 in fibroblasti umani senescenti esposti a stress iperosmolare 134
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines 134
CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells 133
Corrigendum: CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells (Frontiers in Oncology, (2022), 12, (942341), 10.3389/fonc.2022.942341) 131
Effects of FGFR1 inhibition on survival, proliferation, and energy metabolism in Non Small Cell Lung Cancer (NSCLC) cell lines 129
CDK4/6 INHIBITORS AS A NEW THERAPEUTIC APPROACH IN MESOTHELIOMA MODELS 128
Osmotic regulation of ATA2 mRNA expression and amino acid transport system A activity 128
Anti-proliferative and pro-apoptotic effects of Sorafenib in breast cancer cells in vitro. 126
Alterazioni della degradazione proteasoma-dipendente nel corso dell’invecchiamento ed effetti delle restrizioni caloriche 125
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. (Cavazzoni and Bonelli co-first authors) 124
New treatment opportunities in phosphatase and tensin homolo(PTen)-deficient tumors: Focus on PTen/focal adhesion kinase pathway 121
Alterazioni della degradazione proteasoma-dipendente nel corso dell'invecchiamento ed effetti delle restrizioni caloriche 120
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines 119
Roles of compatible osmolytes and heat shock protein 70 in the induction of tolerance to stresses in porcine endothelial cells 118
Anti-proliferative and pro-apoptotic effects of soarfenib in MCF-7/AROM-1 breast cancer cells. 117
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 116
Synergistic activity of letrozole and sorafenib on MCF7/AROM-1 breast cancer cells 112
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 112
Attenuata induzione del gene snat2 in fibroblasti umani senescenti sottoposti a stress iperosmolare 111
Simultaneous Combination of the CDK4/6 Inhibitor Palbociclib With Regorafenib Induces Enhanced Anti-tumor Effects in Hepatocarcinoma Cell Lines 111
Hypertonic stress and amino acid deprivation both increase expression of mRNA for amino acid transport system A 110
Multiple effects of CDK4/6 inhibition in cancer: From cell cycle arrest to immunomodulation 110
Induzione di sistemi di trasporto in condizioni di stress ipertonico 109
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 109
Effects of osmolarity, ions and compatible osmolytes on cell-free protein synthesis 105
Stabilization of hsp70 mRNA on prolonged cell exposure to hypertonicity 103
The effect of heat shock on amino acid transport and cell volume in 3T3 cells 103
Induzione di osmotolleranza in cellule endoteliali derivate da arteria polmonare 102
Targeting oncogenic PI3K/Akt/mTOR pathway in squamous cell lung carcinoma 102
Damage to nuclear DNA induced by Shiga toxin 1 and ricin in human endothelial cells 102
Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts 99
Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones 99
Immunotherapeutic approaches in malignant pleural mesothelioma 97
L’inibizione proteasomica ripristina in cellule senescenti l’espressione di HSP70 92
Espressione Inducibile del gene FHIT in cellule di carcinoma polmonare 92
Hyperosmotic stress response 92
Effect of proteasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 91
Trastuzumab emtansine delays and overcomes resistance to the third-generation EGFR-TKI osimertinib in NSCLC EGFR mutated cell lines 91
Overcoming resistance of EGFR tyrosine kinase inhibitors by new cytostatic and proapoptotic drugs in non small cell lung cancer cell lines 90
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti. 88
Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines 88
Effect of letrozole and sorafenib on cell proliferation and apoptosis of MCF-7/AROM-1 breast cancer cell line 87
Synergistic activity of letrozole and sorafenib on breast cancer cells 86
Increased level of inducible HSP70 in cells exposed to electromagnetic fields. 86
Synergic anti-proliferative effect of gefitinib and RAD001 in non small cell lung cancer cell lines 86
Risposta adattativa di cellule endoteliali a stress iperosmolare 85
Inhibition of Human Malignant Pleural Mesothelioma Growth by Mesenchymal Stromal Cells 84
L'inibizione dell'attività proteasomica ripristina la capacità dei fibroblasti umani senescenti di rispondere allo shock termico 84
Effetto dell’inibizione proteasomica sull’espressione del gene HSP70 in cellule senescenti. 83
Targeting FGFR1 pathway in squamous cell lung cancer 83
Erlotinib potentiates Cetuximab-dependent call citotoxicity in EGFR wild type NSCLC cell lines 83
Effect of protesasome inhibition on HSP70 gene expression in human fibroblasts aging in vitro 82
Targeting PI3K/AKT/mTOR pathway in non small cell lung cancer 82
Shiga toxin 1 and ricin inhibit thr repair of H2O2-induced DNA single strand breks in cultured mammalian cells 82
Pure anti-tumor effect of zoledronic acid in naive bone-only metastatic and locally advanced breast cancer: proof from the "biological window therapy" 81
Hyperosmotic stress response 81
Increased level of 70-kDa Heat Shock Protein in human cells exposed to electromagnetic fields. 80
Induzione differenziale da ipertonicità delle attività di trasporto dei sistemi A e BGT-1 in cellule endoteliali 80
Evaluation of gefitinib maintenance in an EGFR-mutant NSCLC cell line with acquired resistance 80
L’inibizione dei proteasomi ripristina l’espressione del gene HSP70 in fibroblasti umani senescenti 79
Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro 77
Proteasome inhibition restores accumulation of HSP72 and HuR proteins in human fibroblasts aged in vitro 77
Evaluation of gefitinib maintenance in an EGFR-mutant NSCL cell line with acquired resistance 73
New therapeutic strategies for malignant pleural mesothelioma 73
Proteasome inhibition during heat shock restores synthesis and accumulation of HSP72 protein in human fibroblasts aged in vitro. 72
Totale 12.151
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Categoria #
all - tutte 44.611
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.611
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021475 0 0 0 0 0 14 74 31 133 24 162 37
2021/2022560 30 19 27 47 19 10 86 61 31 38 37 155
2022/20232.062 222 200 133 130 235 229 17 114 658 7 91 26
2023/2024880 38 62 30 39 66 186 64 66 36 51 95 147
2024/20252.729 93 146 173 185 239 284 173 138 340 236 257 465
2025/20263.308 491 560 786 579 851 41 0 0 0 0 0 0
Totale 12.892