IRIS
INCERTI, Matteo
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 4.620
EU - Europa 3.996
AS - Asia 3.838
SA - Sud America 671
AF - Africa 210
OC - Oceania 2
Totale 13.337
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 4.491
SG - Singapore 1.504
CN - Cina 1.408
IT - Italia 874
IE - Irlanda 641
FI - Finlandia 609
SE - Svezia 567
BR - Brasile 551
DE - Germania 413
HK - Hong Kong 314
UA - Ucraina 308
VN - Vietnam 242
NL - Olanda 133
ZA - Sudafrica 133
TR - Turchia 105
GB - Regno Unito 95
CA - Canada 83
FR - Francia 77
RU - Federazione Russa 74
IN - India 72
AR - Argentina 61
AT - Austria 50
BE - Belgio 37
CI - Costa d'Avorio 37
MX - Messico 30
JP - Giappone 29
BD - Bangladesh 26
ID - Indonesia 26
CZ - Repubblica Ceca 22
EC - Ecuador 20
GR - Grecia 20
IQ - Iraq 20
KR - Corea 20
ES - Italia 15
HU - Ungheria 13
LT - Lituania 13
MA - Marocco 13
PL - Polonia 12
VE - Venezuela 11
PK - Pakistan 9
EG - Egitto 8
CL - Cile 7
TN - Tunisia 7
UZ - Uzbekistan 7
CO - Colombia 6
KE - Kenya 6
PY - Paraguay 6
SA - Arabia Saudita 6
IL - Israele 5
IR - Iran 5
JM - Giamaica 5
AL - Albania 4
JO - Giordania 4
LB - Libano 4
NP - Nepal 4
UY - Uruguay 4
AZ - Azerbaigian 3
CH - Svizzera 3
KG - Kirghizistan 3
MY - Malesia 3
NO - Norvegia 3
PA - Panama 3
PE - Perù 3
RO - Romania 3
SN - Senegal 3
AE - Emirati Arabi Uniti 2
AM - Armenia 2
AU - Australia 2
BH - Bahrain 2
BO - Bolivia 2
DK - Danimarca 2
KH - Cambogia 2
KZ - Kazakistan 2
NG - Nigeria 2
OM - Oman 2
PH - Filippine 2
SV - El Salvador 2
TH - Thailandia 2
AD - Andorra 1
BB - Barbados 1
BG - Bulgaria 1
BY - Bielorussia 1
CY - Cipro 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
EE - Estonia 1
GT - Guatemala 1
HN - Honduras 1
HR - Croazia 1
LK - Sri Lanka 1
LV - Lettonia 1
NI - Nicaragua 1
RS - Serbia 1
SI - Slovenia 1
TW - Taiwan 1
VG - Isole Vergini Britanniche 1
Totale 13.337
Salva come PNG Salva come JPEG
Città #
Singapore 713
Dublin 640
Chandler 551
Ashburn 485
Beijing 424
Santa Clara 386
Jacksonville 347
Parma 318
Hong Kong 305
Dallas 282
Ann Arbor 251
Dearborn 185
Boardman 167
Nanjing 155
Johannesburg 126
Shanghai 112
Princeton 108
New York 106
Los Angeles 96
Izmir 88
Munich 87
Wilmington 83
San Mateo 79
Ho Chi Minh City 78
Hefei 70
Bremen 66
Hanoi 60
Helsinki 55
São Paulo 55
Toronto 55
Shenyang 50
Vienna 48
Chicago 44
Kunming 44
Grafing 39
Abidjan 37
Moscow 37
Hebei 36
Nanchang 36
Buffalo 35
Jinan 35
Columbus 33
Guangzhou 33
Brussels 31
Bologna 30
Des Moines 28
Tianjin 28
Turku 26
Tokyo 25
Milan 24
Rome 24
Seattle 24
Houston 23
Council Bluffs 22
Woodbridge 22
Jiaxing 21
Pune 20
Rio de Janeiro 20
The Dalles 20
Changsha 19
Jakarta 18
Modena 18
London 16
Seoul 16
Brasília 15
Frankfurt am Main 15
Belo Horizonte 14
Brooklyn 14
Fremont 14
San Francisco 14
Brescia 13
Denver 13
Haiphong 13
Hangzhou 13
Montreal 13
Nuremberg 13
Brno 12
Norwalk 12
Zhengzhou 12
Athens 11
Chennai 11
Mexico City 11
Poplar 11
Ankara 10
Curitiba 10
Düsseldorf 10
Phoenix 10
Boston 9
Fuzhou 9
Ninh Bình 9
Salvador 9
Warsaw 9
Atlanta 8
Hyderabad 8
Kavala 8
Ottawa 8
Stockholm 8
Taizhou 8
Amsterdam 7
Bắc Ninh 7
Totale 7.906
Salva come PNG Salva come JPEG
Nome #
Hydroxyphenyl thiosemicarbazones as inhibitors of mushroom tyrosinase and antibrowning agents. 239
A New ABCB1 Inhibitor Enhances the Anticancer Effect of Doxorubicin in Both In Vitro and In Vivo Models of NSCLC 225
Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice 208
A potentiometric and spectrofluorimetric approach to unravel inhibitory effects of semi- and thiosemicarbazones on mushroom tyrosinase activity 202
Effetto di derivati dell'urea sulla radicazione avventizia in vitro di microtalee micropropagate di corbezzolo 196
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties 188
Pharmacological evaluation of new bioavailable small molecules targeting Eph/ephrin interaction 180
UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations. 177
Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity. 170
Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses 170
A new efficient route to 7-aryl-6-fluoro-8-nitroquinolones as potent antibacterial agents 164
Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction 164
Effect of Cl-Substitution on Rooting- or Cytokinin-like Activity of Diphenylurea Derivatives 161
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. 159
Adventitious rooting adjuvant activity of 1,3-di(benzo[d]oxazol-5-yl) urea and 1,3-di(benzo[d]oxazol-6-yl)urea: new insights and perspectives 158
Probucol treatment is associated with an ABCA1-independent mechanism of cholesterol efflux to lipid poor apolipoproteins from foam cell macrophages 157
Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph–Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavailability in Mice 154
inibitori eph-ephrin biodisponibili oralmente 152
4-Chloro-N-(4-chlorophenylsulfonyl)-N-(3-oxo-2,3-dihydro-1,2-benzisothiazol-2-yl)benzenesulfonamide 151
Structure–Activity Relationships and Mechanism of Action of Eph–ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor 150
Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation 148
Discovery and development of Eph-ephrin antagonists endowed with antiangiogenic properties 148
A one-pot PPh3-promoted synthesis of new functionalized heterocycles derived from 2-aminobenzo[d]isothiazol-3-one 145
Design and structure-activity relationship of amino acid derivatives of lithocholic acid as novel EphA2 antagonists 143
Probing the effects of MR120 in preclinical chronic colitis: A first-in-class anti-IBD agent targeting the CCL20/CCR6 axis 142
A ONE-POT ENTRY TO A NOVEL 3-H-BENZO[D]PYRAZOLO[1,5-B]ISOTHIAZOLE RING SYSTEM. 139
2-Benzo[d]isothiazolylimino-5-arylidene-4-thiazolidinones: Synthesis and antimicrobial activity 139
Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis 137
Discovery and development of small molecules targeting Eph-ephrin system in glioblastoma: an academic history 135
2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. 134
Eph/ephrin targeting with a small molecule improves glucose tolerance in healthy and insulin-resistant mice 132
2-Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as protective agents against cartilage destruction 132
Multiple approaches for the discovery and development of small molecules targeting Eph-ephrin protein-protein interaction 131
4-Methyl-N-(3-oxo-2,3-dihydro-1,2-benzisothiazol-2-yl)benzenesulfonamide 130
2-Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as protective agents against cartilage destruction. 129
Design and structure-activity relationships of amino acid derivatives of lithocholic acid as novel EphA2 receptor antagonists. 129
270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors 129
New MDR1 inhibitors for overcoming multidrug resistance 129
Δ5-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system 127
Amidinobenzisothiazole derivatives with antidegenerative activity on cartilage 126
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists 126
Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis 125
Evaluation of the anti-tumor activity of small molecules targeting eph/ephrins in apcmin j mice 124
Aminoderivatives of benzothiazole/benzisothiazole heterocycles as intermediates in the synthesis of novel therapeutic agents 121
Structure activity relationship of new EphA2 ligands 120
Synthesis and NMR spectral assignments of novel 1,4-benzothiazepine-5-one derivatives 119
Structure-activity relationships of N-phenyl-N’-benzothiazol-6-ylurea synthetic derivatives: cytokinin-like activity and adventitious rooting enhancement 119
Discovery and development of low molecular weight Eph-ephrin protein-protein inhbi-tors endowed with antiangiogenic activity 119
2-BENZO[d]ISOTHIAZOLYLIMINO-5-ARYLIDENE-4-THIAZOLIDINONES: SYNTHESIS AND ANTIMICROBIAL ACTIVITY 118
Dual-Acting Drugs: an in vitro Study of Nonimidazole Histamine H(3) Receptor Antagonists Combining Anticholinesterase Activity 117
Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction. 117
4-thiazolidinone derivatives as MMP inhibitors in tissue damage: Synthesis, biological evaluation and docking studies 116
Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return 116
Metadynamics for perspective drug design: Computationally driven synthesis of new protein-protein interaction inhibitors targeting the EphA2 receptor 115
A one-pot PPh3-promoted synthesis of new functionalized heterocycles derived from 2-aminobenzo[d]isothiazol-3-one 113
Target Hopping as a Useful Tool for the Identification of Novel EphA2 Protein–Protein Antagonists 113
Attività antiproliferativa di N-(1,2-benzisothiaziol-3-il)benzaamidine su cellule di carcinoma colon-rettale umano 113
Diheteroarylurea derivatives as adventitious rooting adjuvants in mung bean shoots and M26 apple rootstock. 112
Are we using the right pharmacological tools to target EphA4? 108
Effects of a dietary intervention with Mediterranean vs lacto-ovo vegetarian diets on HDL function: results from the CARDIVEG study 107
Synthesis and antimicrobial properties of benzothiazole benzenesulfonamides 107
Synthesis and antimicrobial properties of 2-(benzylidene -amino)-benzo[d]isothiazol-3-ones 106
Complete 1H and 13C NMR spectral assignment of benzo[d]isothiazole derivatives and of an isoindole isoster 106
Lithocholic acid competitively inhibits EphA2-ephrinA1 binding: pharmacological and structural considerations. 106
Lithocholic acid competitively inhibitis EphA2-ephrinA1 binding: pharmacological and structural considerations. 106
Synthesis and antiproliferative activity of novel benzo[d]isothiazole compounds bearing a 2,4-dinitrophenyl group. 105
QSAR analysis of 4-thiazolidinone derivatives with antimicrobial activity. 104
Weakly cytokinin-active diphenylurea derivatives influence adventitious rooting in M26 Malus pumila microcuttings 104
Anti-HIV evaluation of benzo[d]isothiazole hydrazones. 102
New ALKBH2 and ALKBH5 inhibitors for treating glioblastoma 101
Antidegenerative activity of heteroarylimino-4-thiazolidinones on human chondrocyte cultures stimulated by IL-1ß 101
Synthesis and pharmacological properties of benzisothiazole/benzimidazole derivatives with acidic groups 101
Synthesis and biological evaluation of benzo[d]isothiazole, benzothiazole and thiazole Schiff bases 100
Design synthesis and antibacterial activity studies of new thiadiazoloquinolone compounds 99
Computer-Aided Design of Novel Antagonists of the EphA2 Receptor 99
Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor. 98
Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation. 98
Heterocycles [h]-fused to 4-oxoquinoline-3-carboxylic acid. Part XI: Synthesis and antibacterial activity of 4-fluoro-6-oxoimidazo[4,5-h]quinoline-7-carboxylic acids 97
Thiazolyl and isothiazolyl azomethine derivatives with antiinflammatory and antioxidant activities. Synthesis, biological evaluation and structure activity relationships study 96
Multi-target-directed ligands: new histamine H3 receptor antagonists with anticholinesterase activity 96
Lipophilicity estimation of new benzisothiazolone derivatives with anti HIV-1 activity for a rational study of structure-activity relationship 95
Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as potential biologically active agents 95
Target-hopping: a useful approach to identify novel Eph receptor antagonists 94
Synthesis of benzisoxazole and benzisothiazole derivatives with potential antitumor activity 93
On the Use of 2,5-Dimethyl-Pyrrol-1-yl-Benzoic Acid Derivatives as EPH-Ephrin Antagonists. 92
Synthesis and effect of new N-(1,2-benzo[d]isothiazol-3-yl) benzamidines on IL-1- induced alteration in cartilage metabolism 91
Stereospecific effects of benzo(d)isothiazolyloxypropanolamine derivatives at beta-adrenoceptors: synthesis, chiral resolution, and biological activity in vitro 91
Benzisothiazolyliminothiazolidin-4-ones with chondroprotective properties: searching for potent and selective inhibitors of MMP-13. 91
Nucleoside Derivatives of 2,6-Diaminopurine Antivirals: Base-Modified Nucleosides with Broad-Spectrum Antimicrobial Properties 90
Synthesis and evaluation as antimicrobial agents of novel heteroaryl sulfonamides 89
Synthesis of novel 5-arylidene-thiazol-4-ones 2-heteroarylamino substituted as potential antimicrobials 89
Synthesis and biological activity of hydrazones of benzo[d]isothiazole hydrazides 89
Investigation of the reaction between 3-benzisothiazolones, an isoindole isoster and activated acetylenes: synthesis of novel heterocyclic backbones for building bioactive molecules 86
Lomitapide modifies high-density lipoprotein function in homozygous familial hypercholesterolaemia 82
Benzo[d]isothiazol-3-yl-benzamidines: a class of protective agents on culture of human cartilage and chondrocytes stimulated by IL-1ß. 81
Synthesis and Anticancer Activity of new amidinobenzisothiazoles 81
Molecular modeling of binding between amidinobenzisothiazoles, with antidegenerative activity on cartilage, and matrix metalloproteinase-3 80
In vitro and in vivo efficacy of an orally bioavailable antagonist of Eph-ephrin system in tumor angiogenesis and growth 77
Evaluation of the antiproliferative activity of benzofused nitrogen and sulfur/oxygen containig heterocycles derivatives 75
Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents 75
Totale 12.335
Salva come PNG Salva come JPEG
Categoria #
all - tutte 46.951
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.951
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021450 0 0 0 0 0 29 95 24 127 44 100 31
2021/2022674 24 15 20 70 24 55 70 87 37 55 25 192
2022/20232.326 245 261 126 169 217 240 44 145 763 20 62 34
2023/2024858 56 64 40 23 60 191 95 65 20 36 68 140
2024/20252.731 92 166 189 150 305 298 138 127 295 235 241 495
2025/20263.325 545 576 683 629 836 56 0 0 0 0 0 0
Totale 13.514