IRIS
INCERTI, Matteo
 Distribuzione geografica
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Continente #
EU - Europa 3.328
NA - Nord America 2.758
AS - Asia 1.248
AF - Africa 39
OC - Oceania 2
SA - Sud America 2
Totale 7.377
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Nazione #
US - Stati Uniti d'America 2.713
CN - Cina 990
IT - Italia 751
IE - Irlanda 640
FI - Finlandia 565
SE - Svezia 558
UA - Ucraina 300
DE - Germania 292
SG - Singapore 112
TR - Turchia 94
FR - Francia 52
GB - Regno Unito 47
CA - Canada 45
AT - Austria 42
CI - Costa d'Avorio 36
BE - Belgio 31
IN - India 31
CZ - Repubblica Ceca 18
HU - Ungheria 8
GR - Grecia 7
HK - Hong Kong 5
JP - Giappone 5
NL - Olanda 5
KR - Corea 4
AU - Australia 2
IR - Iran 2
LT - Lituania 2
NG - Nigeria 2
RO - Romania 2
VN - Vietnam 2
AL - Albania 1
AR - Argentina 1
BG - Bulgaria 1
CH - Svizzera 1
CO - Colombia 1
ES - Italia 1
HR - Croazia 1
IQ - Iraq 1
MY - Malesia 1
NO - Norvegia 1
PK - Pakistan 1
RS - Serbia 1
RU - Federazione Russa 1
TN - Tunisia 1
Totale 7.377
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Città #
Dublin 639
Chandler 551
Jacksonville 346
Parma 276
Beijing 265
Ann Arbor 251
Dearborn 185
Ashburn 162
Nanjing 153
Princeton 108
Shanghai 107
Izmir 88
Wilmington 83
San Mateo 79
New York 71
Bremen 66
Singapore 62
Boardman 50
Shenyang 49
Kunming 43
Toronto 41
Vienna 41
Hefei 40
Grafing 39
Helsinki 37
Abidjan 36
Hebei 36
Nanchang 36
Chicago 35
Jinan 35
Des Moines 28
Guangzhou 27
Brussels 25
Bologna 24
Woodbridge 22
Jiaxing 21
Seattle 20
Los Angeles 19
Pune 19
Tianjin 19
Rome 18
Changsha 16
Milan 15
Fremont 14
Houston 14
Modena 14
Hangzhou 13
Brno 12
Norwalk 12
Zhengzhou 12
Brescia 10
Düsseldorf 10
Fuzhou 8
Taizhou 8
Athens 7
Haikou 7
Taiyuan 7
Auburn Hills 6
Borås 6
Ningbo 6
Palermo 6
Pesaro 6
Solaro 6
Ankara 5
Carpi 5
Castello Molina di Fiemme 5
Chengdu 5
Hyderabad 5
Prata Di Pordenone 5
Redwood City 5
Altidona 4
Lanzhou 4
Leuven 4
London 4
Montecchio Emilia 4
Paris 4
Piacenza 4
Reggio Emilia 4
Reggio Nell'emilia 4
Sant'ilario D'enza 4
Tulsa 4
Vigevano 4
Wenzhou 4
Xian 4
Albignasego 3
Bisceglie 3
Caorso 3
Carrara 3
Compiano 3
Finale Emilia 3
Fiorenzuola d'Arda 3
Magdeburg 3
Montabone 3
Munich 3
Ottawa 3
Pavia 3
Piemonte 3
Poggio Renatico 3
Tokyo 3
Augusta 2
Totale 4.605
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Nome #
Hydroxyphenyl thiosemicarbazones as inhibitors of mushroom tyrosinase and antibrowning agents. 168
Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice 150
UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations. 132
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties 123
Effetto di derivati dell'urea sulla radicazione avventizia in vitro di microtalee micropropagate di corbezzolo 122
inibitori eph-ephrin biodisponibili oralmente 119
A New ABCB1 Inhibitor Enhances the Anticancer Effect of Doxorubicin in Both In Vitro and In Vivo Models of NSCLC 114
Pharmacological evaluation of new bioavailable small molecules targeting Eph/ephrin interaction 112
Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity. 105
Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation 104
Effect of Cl-Substitution on Rooting- or Cytokinin-like Activity of Diphenylurea Derivatives 101
Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction 98
Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph–Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavailability in Mice 98
Adventitious rooting adjuvant activity of 1,3-di(benzo[d]oxazol-5-yl) urea and 1,3-di(benzo[d]oxazol-6-yl)urea: new insights and perspectives 94
Structure–Activity Relationships and Mechanism of Action of Eph–ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor 92
New MDR1 inhibitors for overcoming multidrug resistance 90
A one-pot PPh3-promoted synthesis of new functionalized heterocycles derived from 2-aminobenzo[d]isothiazol-3-one 89
2-Benzo[d]isothiazolylimino-5-arylidene-4-thiazolidinones: Synthesis and antimicrobial activity 89
Probucol treatment is associated with an ABCA1-independent mechanism of cholesterol efflux to lipid poor apolipoproteins from foam cell macrophages 89
A new efficient route to 7-aryl-6-fluoro-8-nitroquinolones as potent antibacterial agents 88
Design and structure-activity relationship of amino acid derivatives of lithocholic acid as novel EphA2 antagonists 86
Discovery and development of small molecules targeting Eph-ephrin system in glioblastoma: an academic history 83
4-Chloro-N-(4-chlorophenylsulfonyl)-N-(3-oxo-2,3-dihydro-1,2-benzisothiazol-2-yl)benzenesulfonamide 82
Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses 80
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. 79
Multiple approaches for the discovery and development of small molecules targeting Eph-ephrin protein-protein interaction 77
Amidinobenzisothiazole derivatives with antidegenerative activity on cartilage 74
Eph/ephrin targeting with a small molecule improves glucose tolerance in healthy and insulin-resistant mice 74
Metadynamics for perspective drug design: Computationally driven synthesis of new protein-protein interaction inhibitors targeting the EphA2 receptor 74
Diheteroarylurea derivatives as adventitious rooting adjuvants in mung bean shoots and M26 apple rootstock. 73
Discovery and development of Eph-ephrin antagonists endowed with antiangiogenic properties 73
Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis 73
Complete 1H and 13C NMR spectral assignment of benzo[d]isothiazole derivatives and of an isoindole isoster 72
Design and structure-activity relationships of amino acid derivatives of lithocholic acid as novel EphA2 receptor antagonists. 71
Synthesis and NMR spectral assignments of novel 1,4-benzothiazepine-5-one derivatives 70
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists 70
Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction. 70
Dual-Acting Drugs: an in vitro Study of Nonimidazole Histamine H(3) Receptor Antagonists Combining Anticholinesterase Activity 68
Synthesis and antimicrobial properties of 2-(benzylidene -amino)-benzo[d]isothiazol-3-ones 67
A ONE-POT ENTRY TO A NOVEL 3-H-BENZO[D]PYRAZOLO[1,5-B]ISOTHIAZOLE RING SYSTEM. 67
Target Hopping as a Useful Tool for the Identification of Novel EphA2 Protein–Protein Antagonists 67
270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors 66
Discovery and development of low molecular weight Eph-ephrin protein-protein inhbi-tors endowed with antiangiogenic activity 66
Aminoderivatives of benzothiazole/benzisothiazole heterocycles as intermediates in the synthesis of novel therapeutic agents 65
Anti-HIV evaluation of benzo[d]isothiazole hydrazones. 65
Structure activity relationship of new EphA2 ligands 65
2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. 65
Evaluation of the anti-tumor activity of small molecules targeting eph/ephrins in apcmin j mice 65
Thiazolyl and isothiazolyl azomethine derivatives with antiinflammatory and antioxidant activities. Synthesis, biological evaluation and structure activity relationships study 64
4-Methyl-N-(3-oxo-2,3-dihydro-1,2-benzisothiazol-2-yl)benzenesulfonamide 64
Attività antiproliferativa di N-(1,2-benzisothiaziol-3-il)benzaamidine su cellule di carcinoma colon-rettale umano 64
Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis 64
Design synthesis and antibacterial activity studies of new thiadiazoloquinolone compounds 63
Δ5-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system 63
2-Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as protective agents against cartilage destruction 63
Structure-activity relationships of N-phenyl-N’-benzothiazol-6-ylurea synthetic derivatives: cytokinin-like activity and adventitious rooting enhancement 62
2-Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as protective agents against cartilage destruction. 62
On the Use of 2,5-Dimethyl-Pyrrol-1-yl-Benzoic Acid Derivatives as EPH-Ephrin Antagonists. 62
Benzisothiazolylimino-5-benzylidene-4-thiazolidinones as potential biologically active agents 62
A one-pot PPh3-promoted synthesis of new functionalized heterocycles derived from 2-aminobenzo[d]isothiazol-3-one 61
Lithocholic acid competitively inhibits EphA2-ephrinA1 binding: pharmacological and structural considerations. 61
Lithocholic acid competitively inhibitis EphA2-ephrinA1 binding: pharmacological and structural considerations. 61
Synthesis and pharmacological properties of benzisothiazole/benzimidazole derivatives with acidic groups 61
Probing the effects of MR120 in preclinical chronic colitis: A first-in-class anti-IBD agent targeting the CCL20/CCR6 axis 60
Synthesis and biological evaluation of benzo[d]isothiazole, benzothiazole and thiazole Schiff bases 60
Lithocholic Acid Is an Eph-ephrin Ligand Interfering with Eph-kinase Activation. 60
Heterocycles [h]-fused to 4-oxoquinoline-3-carboxylic acid. Part XI: Synthesis and antibacterial activity of 4-fluoro-6-oxoimidazo[4,5-h]quinoline-7-carboxylic acids 60
Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return 60
Multi-target-directed ligands: new histamine H3 receptor antagonists with anticholinesterase activity 60
A potentiometric and spectrofluorimetric approach to unravel inhibitory effects of semi- and thiosemicarbazones on mushroom tyrosinase activity 58
Antidegenerative activity of heteroarylimino-4-thiazolidinones on human chondrocyte cultures stimulated by IL-1ß 58
Weakly cytokinin-active diphenylurea derivatives influence adventitious rooting in M26 Malus pumila microcuttings 58
Synthesis and antimicrobial properties of benzothiazole benzenesulfonamides 57
2-BENZO[d]ISOTHIAZOLYLIMINO-5-ARYLIDENE-4-THIAZOLIDINONES: SYNTHESIS AND ANTIMICROBIAL ACTIVITY 57
QSAR analysis of 4-thiazolidinone derivatives with antimicrobial activity. 56
Synthesis and antiproliferative activity of novel benzo[d]isothiazole compounds bearing a 2,4-dinitrophenyl group. 56
Are we using the right pharmacological tools to target EphA4? 55
Stereospecific effects of benzo(d)isothiazolyloxypropanolamine derivatives at beta-adrenoceptors: synthesis, chiral resolution, and biological activity in vitro 55
Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor. 54
4-thiazolidinone derivatives as MMP inhibitors in tissue damage: Synthesis, biological evaluation and docking studies 54
Investigation of the reaction between 3-benzisothiazolones, an isoindole isoster and activated acetylenes: synthesis of novel heterocyclic backbones for building bioactive molecules 52
In vitro and in vivo efficacy of an orally bioavailable antagonist of Eph-ephrin system in tumor angiogenesis and growth 52
Synthesis of benzisoxazole and benzisothiazole derivatives with potential antitumor activity 51
Synthesis and biological activity of hydrazones of benzo[d]isothiazole hydrazides 51
Target-hopping: a useful approach to identify novel Eph receptor antagonists 50
Computer-Aided Design of Novel Antagonists of the EphA2 Receptor 50
Benzisothiazolyliminothiazolidin-4-ones with chondroprotective properties: searching for potent and selective inhibitors of MMP-13. 49
Benzo[d]isothiazol-3-yl-benzamidines: a class of protective agents on culture of human cartilage and chondrocytes stimulated by IL-1ß. 48
Lipophilicity estimation of new benzisothiazolone derivatives with anti HIV-1 activity for a rational study of structure-activity relationship 48
Synthesis and evaluation as antimicrobial agents of novel heteroaryl sulfonamides 47
Molecular modeling of binding between amidinobenzisothiazoles, with antidegenerative activity on cartilage, and matrix metalloproteinase-3 47
Synthesis of novel 5-arylidene-thiazol-4-ones 2-heteroarylamino substituted as potential antimicrobials 45
Synthesis and antimicrobial activity of benzylidene derivatives of 2-(benzo[d]thiazol-2-ylimino)thiazolidin-4-one 45
Evaluation of the antiproliferative activity of benzofused nitrogen and sulfur/oxygen containig heterocycles derivatives 45
Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents 45
Targeting Eph/ephrin system in cancer therapy 43
Synthesis and antimicrobial activity of novel 2-thiazolylimino-5-arylidene-4-thiazolidinones 42
Hybrid molecules between benzenesulfonamides and active antimicrobial benzo[d]isothiazol-3-ones. 42
Benzo[d]isothiazol-3-yl-benzamidines : a new class of protective agents on culture of human chondrocytes stimulated by IL-1B 42
Synthesis and Anticancer Activity of new amidinobenzisothiazoles 41
Totale 7.034
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Categoria #
all - tutte 24.897
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.897
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.512 233 274 87 25 112 154 179 42 160 134 32 80
2020/2021784 20 78 76 56 104 29 95 24 127 44 100 31
2021/2022674 24 15 20 70 24 55 70 87 37 55 25 192
2022/20232.326 245 261 126 169 217 240 44 145 763 20 62 34
2023/2024858 56 64 40 23 60 191 95 65 20 36 68 140
2024/202582 82 0 0 0 0 0 0 0 0 0 0 0
Totale 7.540