Some years ago we demonstrated the cytokinin-like activity of the synthetic N-phenyl-N0-benzothiazol- 6-ylurea (PBU) and a relevant adventitious rooting adjuvant activity of symmetric urea derivatives devoid of any cytokinin- or auxin-like activity per se. Here we report the synthesis and the biological activity evaluation of nine symmetric or asymmetric ureas/thioureas, structurally related to PBU. None of them show cytokinin-like activity, while we demonstrate for the first time that PBU interacts with Arabidopsis cytokinin receptor CRE1/AHK4 in a heterologous bioassay system. Among the PBU derivatives, all the symmetric ureas/thioureas show an adventitious rooting adjuvant activity in various bioassays, confirming that this activity is strictly dependent on their chemical structure.

Structure-activity relationships of N-phenyl-N’-benzothiazol-6-ylurea synthetic derivatives: cytokinin-like activity and adventitious rooting enhancement / Rolli, Enrico; Incerti, Matteo; Brunoni, Federica; Vicini, Paola; Ricci, Ada. - In: PHYTOCHEMISTRY. - ISSN 0031-9422. - 74:(2012), pp. 159-165. [10.1016/j.phytochem.2011.10.012]

Structure-activity relationships of N-phenyl-N’-benzothiazol-6-ylurea synthetic derivatives: cytokinin-like activity and adventitious rooting enhancement

ROLLI, Enrico;INCERTI, Matteo;BRUNONI, Federica;VICINI, Paola;RICCI, Ada
2012

Abstract

Some years ago we demonstrated the cytokinin-like activity of the synthetic N-phenyl-N0-benzothiazol- 6-ylurea (PBU) and a relevant adventitious rooting adjuvant activity of symmetric urea derivatives devoid of any cytokinin- or auxin-like activity per se. Here we report the synthesis and the biological activity evaluation of nine symmetric or asymmetric ureas/thioureas, structurally related to PBU. None of them show cytokinin-like activity, while we demonstrate for the first time that PBU interacts with Arabidopsis cytokinin receptor CRE1/AHK4 in a heterologous bioassay system. Among the PBU derivatives, all the symmetric ureas/thioureas show an adventitious rooting adjuvant activity in various bioassays, confirming that this activity is strictly dependent on their chemical structure.
Structure-activity relationships of N-phenyl-N’-benzothiazol-6-ylurea synthetic derivatives: cytokinin-like activity and adventitious rooting enhancement / Rolli, Enrico; Incerti, Matteo; Brunoni, Federica; Vicini, Paola; Ricci, Ada. - In: PHYTOCHEMISTRY. - ISSN 0031-9422. - 74:(2012), pp. 159-165. [10.1016/j.phytochem.2011.10.012]
File in questo prodotto:
File Dimensione Formato  
PHYTO10203.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 773.39 kB
Formato Adobe PDF
773.39 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Abstract PHYTO 10203.doc

non disponibili

Tipologia: Abstract
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 23.5 kB
Formato Microsoft Word
23.5 kB Microsoft Word   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2375716
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 9
  • ???jsp.display-item.citation.isi??? 6
social impact