IRIS
PERACCHI, Alessio
 Distribuzione geografica
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Continente #
NA - Nord America 3.198
AS - Asia 2.231
EU - Europa 2.097
SA - Sud America 407
AF - Africa 186
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.124
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Nazione #
US - Stati Uniti d'America 3.102
SG - Singapore 870
CN - Cina 795
IT - Italia 413
IE - Irlanda 363
BR - Brasile 325
SE - Svezia 274
FI - Finlandia 237
DE - Germania 210
HK - Hong Kong 205
UA - Ucraina 200
VN - Vietnam 143
NL - Olanda 94
ZA - Sudafrica 87
CI - Costa d'Avorio 75
CA - Canada 71
GB - Regno Unito 64
RU - Federazione Russa 57
IN - India 42
BE - Belgio 39
TR - Turchia 39
AR - Argentina 32
PL - Polonia 32
AT - Austria 27
FR - Francia 26
BD - Bangladesh 21
KR - Corea 21
ES - Italia 20
ID - Indonesia 18
EC - Ecuador 15
MX - Messico 13
IQ - Iraq 11
JP - Giappone 10
LU - Lussemburgo 10
CO - Colombia 8
PK - Pakistan 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
CL - Cile 7
CZ - Repubblica Ceca 7
MA - Marocco 7
VE - Venezuela 7
LT - Lituania 6
PY - Paraguay 6
DZ - Algeria 5
IL - Israele 5
IR - Iran 5
KE - Kenya 5
RO - Romania 5
AZ - Azerbaigian 4
HU - Ungheria 4
SA - Arabia Saudita 4
CH - Svizzera 3
HN - Honduras 3
NP - Nepal 3
UY - Uruguay 3
BO - Bolivia 2
EG - Egitto 2
ET - Etiopia 2
JM - Giamaica 2
KZ - Kazakistan 2
MY - Malesia 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PA - Panama 2
PE - Perù 2
TT - Trinidad e Tobago 2
AU - Australia 1
CM - Camerun 1
CR - Costa Rica 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EE - Estonia 1
EU - Europa 1
HR - Croazia 1
JO - Giordania 1
KG - Kirghizistan 1
KW - Kuwait 1
LV - Lettonia 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NO - Norvegia 1
PH - Filippine 1
PS - Palestinian Territory 1
SI - Slovenia 1
TH - Thailandia 1
TJ - Tagikistan 1
TW - Taiwan 1
Totale 8.124
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Città #
Singapore 443
Dallas 410
Dublin 361
Ashburn 341
Chandler 295
Santa Clara 293
Beijing 205
Jacksonville 200
Hong Kong 199
Dearborn 148
Parma 130
Ann Arbor 96
Boardman 95
Nanjing 80
Johannesburg 78
Abidjan 75
Shanghai 74
Los Angeles 67
Princeton 65
Ho Chi Minh City 57
Hefei 53
San Mateo 52
Wilmington 52
Munich 49
New York 43
Hanoi 37
Shenyang 37
Toronto 37
Council Bluffs 32
Bremen 31
Columbus 31
Helsinki 31
Izmir 29
São Paulo 29
Moscow 25
Kunming 24
Buffalo 22
Milan 22
Warsaw 22
Seattle 21
Seoul 21
The Dalles 21
Jinan 19
Vienna 18
Falls Church 17
Louvain 17
Nanchang 17
Woodbridge 17
Brussels 16
Phoenix 16
Jakarta 15
Turku 15
Changsha 14
Hebei 14
Bologna 13
Guangzhou 13
Houston 13
Modena 13
Rho 13
Tianjin 13
Montreal 12
Nuremberg 12
Belo Horizonte 11
Boston 11
Des Moines 11
Fremont 11
Leawood 11
Augusta 10
Rome 10
Tokyo 10
Grafing 9
London 9
Orem 9
Rio de Janeiro 9
Brescia 8
Chengdu 8
Denver 8
Frankfurt am Main 8
Luxembourg 8
Norwalk 8
Tashkent 8
Zhengzhou 8
Amsterdam 7
Brooklyn 7
Cambridge 7
Chennai 7
Chicago 7
Haikou 7
Jiaxing 7
Krakow 7
Mumbai 7
Pittsburgh 7
Shenzhen 7
Taiyuan 7
Atlanta 6
Curitiba 6
Guayaquil 6
Haiphong 6
Padova 6
Poplar 6
Totale 5.035
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Nome #
One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse 198
Birth of a pathway for sulfur metabolism in early amniote evolution 184
A phosphoserine phosphatase variant present in the brain of Alzheimer's disease patients favors nuclear mistargeting 180
Genomic context analysis enables the discovery of an unusual NAD-dependent racemase in phosphonate catabolism 176
Off to a slow start: Analyzing lag phases and accelerating rates in steady-state enzyme kinetics 168
METODO E RELATIVO KIT PER LA DETERMINAZIONE DELLA CONCENTRAZIONE DI FOSFOETANOLAMMINA IN UNA SOLUZIONE ACQUOSA 164
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme 164
Domain organization of phytochelatin synthase: functional properties of truncated enzyme species identified by limited proteolysis 154
Catalysis and electron transfer in protein crystals: the binary and ternary complexes of methylamine dehydrogenase with electron acceptors 151
A threonine synthase homolog from a mammalian genome 148
DNA catalysis: potential, limitations, open questions 143
Allosteric regulation of tryptophan synthase: a pKa change at the beta-active site induced by alpha-subunit ligands 142
Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme 138
Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism 138
Effect of pH and monovalent cations on the formation of quinonoid intermediates of the tryptophan synthase alpha2beta2 complex in solution and in the crystal 137
A continuous kinetic assay for RNA-cleaving deoxyribozymes, exploiting ethidium bromide as an extrinsic fluorescent probe 132
Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants 128
L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase 127
An aminotransferase branch point connects purine catabolism to amino acid recycling 126
ATP binding to human serine racemase is cooperative and modulated by glycine 125
Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase 125
Allosteric regulation of tryptophan synthase: effects of pH, temperature and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate L-serine intermediates 124
Characterization of tryptophan and coenzyme luminescence in tryptophan synthase from Salmonella typhimurium 120
Prospects for antiviral ribozymes and deoxyribozymes 119
A subfamily of PLP-dependent enzymes specialized in handling terminal amines 118
Completing the folate biosynthesis pathway in Plasmodium falciparum: p-aminobenzoate is produced by a highly divergent promiscuous aminodeoxychorismate lyase 117
A mutational analysis of the 8-17 deoxyribozyme core 115
A genomic overview of pyridoxal-phosphate-dependent enzymes 113
The advantages of being locked: assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes 112
Kinetic characterization of the human O-phosphoethanolamine phospho-lyase reveals unconventional features of this specialized pyridoxal phosphate-dependent lyase 108
Discovery of a New, Recurrent Enzyme in Bacterial Phosphonate Degradation: (R)‑1-Hydroxy-2-aminoethylphosphonate Ammonia-lyase 108
Human cytosolic transaminases: side activities and patterns of discrimination towards physiologically available alternative substrates 107
Biological catalysis: Lessons from the comparison of RNA and protein enzymes 107
A core folding model for catalysis by the hammerhead ribozyme accounts for its extraordinary sensitivity to abasic Mutations 105
Time-resolved fluorescence of pyridoxal 5'-phosphate-containing enzymes: tryptophan synthase and O-acetylserine sulfhydrylase 105
Dissecting the hybridization of oligonucleotides to structured complementary sequences 103
Time course of chemical and structural events in protein crystals measured by microspectrophotometry 102
Time resolved fluorescence of tryptophan synthase 102
The B6 database: a tool for the description and classification of vitamin B6-dependent enzymatic activities and of the corresponding protein families. 102
Conformational changes and subunit communication in tryptophan synthase: effect of substrates and substrate analogs 101
Functional Properties of Immobilized Pyridoxal 5'-Phosphate-Dependent Enzymes Probed by Absorption Microspectrophotometry 101
Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism 100
Strict reaction and substrate specificity of AGXT2L1, the human O-phosphoethanolamine phospho-lyase 100
Effects of monovalent cations on functional properties of the tryptophan synthase alpha2beta2 complex in solution and in the crystal 97
Ligand binding to human serine racemase: a spectroscopic and functional study 96
Local conformational changes in the 8–17 deoxyribozyme core induced by activating and inactivating divalent metal ions 96
The human phosphorylated pathway: a multienzyme metabolic assembly for l-serine biosynthesis 95
Microspectrophotometric studies on single crystals of the tryptophan synthase alpha2beta2 complex demonstrate formation of enzyme-substrate intermediates 92
The limits of enzyme specificity and the evolution of metabolism 91
How (and why) to revive a dead enzyme: the power of chemical rescue 89
Insights into DNA catalysis from structural and functional studies of the 8-17 DNAzyme 89
Using Steady-State Kinetics to Quantitate Substrate Selectivity and Specificity: A Case Study with Two Human Transaminases 89
Use of intrinsic binding energy for catalysis by an RNA enzyme 88
Pyridoxal 5’-Phosphate-Dependent Enzymes: Catalysis, Conformation and Genomics 88
Serine racemase: a key player in neuron activity and in neuropathologies 88
Exploring and exploiting allostery: Models, evolution, and drug targeting 87
Human serine racemase, a key enzyme in neurophysiology and neuropathologies 87
The Microbial Degradation of Natural and Anthropogenic Phosphonates 86
Enzyme catalysis: removing chemically "essential" residues by site-directed mutagenesis 85
Regulation of human serine racemase activity and dynamics by halides, ATP and malonate 81
Monovalent cations affect dynamic and functional properties of the tryptophan synthase alpha2beta2 complex 80
Efficient and selective cleavage of RNA oligonucleotides by calix[4]arene-based synthetic metallonucleases 78
Preferential activation of the 8-17 deoxyribozyme by Ca2+ ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme 78
Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization 77
Origins of the temperature dependence of hammerhead ribozyme catalysis 75
Structure-function relationships in the hammerhead ribozyme probed by base rescue 74
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation 74
Identification of the hammerhead ribozyme metal ion binding site responsible for rescue of the deleterious effect of a cleavage site phosphorothioate 72
The putative Escherichia coli dehydrogenase YjhC metabolises two dehydrated forms of N-acetylneuraminate produced by some sialidases 70
Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione 70
Structural characterization of human O-phosphoethanolamine phospho-lyase 69
Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases 67
Enzymes that make and enzymes that fix mistakes: Nit1 is a ‘repair’ amidase that hydrolyzes deaminated glutathione 66
The metalloprotein YhcH is an anomerase providing N-acetylneuraminate aldolase with the open form of its substrate 65
Single crystal polarized absorption microspectrophotometry of aromatic L-aminoacid decarboxylase 64
Human serine racemase, a key enzyme in neurophysiology and neuropathologies 63
Regulation and dynamics of human serine racemase 35
null 28
Totale 8.266
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Categoria #
all - tutte 29.498
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.498
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021327 0 0 0 0 0 5 50 12 119 25 102 14
2021/2022365 7 10 7 47 28 17 30 57 20 24 32 86
2022/20231.256 145 128 64 101 123 136 6 71 413 7 45 17
2023/2024510 27 56 9 24 40 97 50 41 21 29 48 68
2024/20251.888 102 105 143 83 188 255 81 102 169 186 149 325
2025/20262.427 332 594 514 421 535 31 0 0 0 0 0 0
Totale 8.266