IRIS
PERACCHI, Alessio
 Distribuzione geografica
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Continente #
NA - Nord America 3.926
AS - Asia 3.110
EU - Europa 2.310
SA - Sud America 461
AF - Africa 226
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 10.039
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Nazione #
US - Stati Uniti d'America 3.800
SG - Singapore 1.030
CN - Cina 892
IT - Italia 494
VN - Vietnam 480
IE - Irlanda 364
BR - Brasile 346
SE - Svezia 274
HK - Hong Kong 253
FI - Finlandia 239
DE - Germania 218
UA - Ucraina 202
BD - Bangladesh 155
ZA - Sudafrica 109
FR - Francia 106
NL - Olanda 98
CA - Canada 87
CI - Costa d'Avorio 77
GB - Regno Unito 73
IN - India 59
RU - Federazione Russa 59
TR - Turchia 45
AR - Argentina 41
BE - Belgio 39
PL - Polonia 36
AT - Austria 30
ES - Italia 30
KR - Corea 25
IQ - Iraq 24
ID - Indonesia 23
EC - Ecuador 20
MX - Messico 20
PK - Pakistan 17
CO - Colombia 13
JP - Giappone 13
TH - Thailandia 12
UZ - Uzbekistan 12
CL - Cile 11
MA - Marocco 11
PH - Filippine 11
VE - Venezuela 11
LU - Lussemburgo 10
AE - Emirati Arabi Uniti 8
CZ - Repubblica Ceca 8
LT - Lituania 7
MY - Malesia 7
PY - Paraguay 7
IL - Israele 6
CH - Svizzera 5
DZ - Algeria 5
ET - Etiopia 5
HN - Honduras 5
IR - Iran 5
KE - Kenya 5
NP - Nepal 5
RO - Romania 5
SA - Arabia Saudita 5
UY - Uruguay 5
AZ - Azerbaigian 4
BO - Bolivia 4
HU - Ungheria 4
JM - Giamaica 4
TW - Taiwan 4
EG - Egitto 3
JO - Giordania 3
KZ - Kazakistan 3
PE - Perù 3
SN - Senegal 3
AU - Australia 2
CM - Camerun 2
CR - Costa Rica 2
KG - Kirghizistan 2
KW - Kuwait 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PA - Panama 2
PS - Palestinian Territory 2
TN - Tunisia 2
TT - Trinidad e Tobago 2
AM - Armenia 1
BG - Bulgaria 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
EE - Estonia 1
EU - Europa 1
GT - Guatemala 1
HR - Croazia 1
LV - Lettonia 1
LY - Libia 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
NO - Norvegia 1
OM - Oman 1
PT - Portogallo 1
RS - Serbia 1
SI - Slovenia 1
TC - Turks e Caicos 1
TG - Togo 1
TJ - Tagikistan 1
Totale 10.039
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Città #
Singapore 528
Ashburn 430
Dallas 419
Dublin 362
San Jose 346
Santa Clara 305
Chandler 295
Hong Kong 235
Beijing 209
Jacksonville 200
Ho Chi Minh City 150
Dearborn 148
Parma 130
Boardman 109
Hanoi 105
Johannesburg 100
Ann Arbor 96
Los Angeles 86
Nanjing 80
Abidjan 77
Shanghai 74
Lauterbourg 71
Princeton 65
New York 64
Hefei 53
San Mateo 52
Wilmington 52
Munich 49
Council Bluffs 46
Buffalo 41
Toronto 41
Columbus 37
Shenyang 37
Helsinki 33
Bremen 31
São Paulo 31
The Dalles 30
Izmir 29
Milan 28
Warsaw 26
Moscow 25
Kunming 24
Haiphong 22
Seattle 22
Phoenix 21
Seoul 21
Rome 20
Vienna 20
Jinan 19
Bologna 18
Da Nang 18
Falls Church 17
Louvain 17
Nanchang 17
Orem 17
Woodbridge 17
Brussels 16
Des Moines 16
Houston 15
Jakarta 15
Montreal 15
Turku 15
Changsha 14
Frankfurt am Main 14
Hebei 14
Tianjin 14
Biên Hòa 13
Guangzhou 13
Modena 13
Rho 13
Baghdad 12
Nuremberg 12
Tashkent 12
Belo Horizonte 11
Boston 11
Denver 11
Fremont 11
Leawood 11
Amsterdam 10
Augusta 10
Chicago 10
London 10
Tokyo 10
Brescia 9
Chennai 9
Grafing 9
Rio de Janeiro 9
Chengdu 8
Guayaquil 8
Luxembourg 8
Norwalk 8
Poplar 8
Reggio Emilia 8
Zhengzhou 8
Atlanta 7
Brooklyn 7
Cambridge 7
Curitiba 7
Haikou 7
Hải Dương 7
Totale 6.090
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Nome #
One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse 234
Genomic context analysis enables the discovery of an unusual NAD-dependent racemase in phosphonate catabolism 231
A phosphoserine phosphatase variant present in the brain of Alzheimer's disease patients favors nuclear mistargeting 228
Birth of a pathway for sulfur metabolism in early amniote evolution 219
Off to a slow start: Analyzing lag phases and accelerating rates in steady-state enzyme kinetics 195
L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase 194
ATP binding to human serine racemase is cooperative and modulated by glycine 194
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme 191
A threonine synthase homolog from a mammalian genome 186
METODO E RELATIVO KIT PER LA DETERMINAZIONE DELLA CONCENTRAZIONE DI FOSFOETANOLAMMINA IN UNA SOLUZIONE ACQUOSA 184
Domain organization of phytochelatin synthase: functional properties of truncated enzyme species identified by limited proteolysis 182
Catalysis and electron transfer in protein crystals: the binary and ternary complexes of methylamine dehydrogenase with electron acceptors 182
Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants 169
Allosteric regulation of tryptophan synthase: a pKa change at the beta-active site induced by alpha-subunit ligands 165
An aminotransferase branch point connects purine catabolism to amino acid recycling 161
DNA catalysis: potential, limitations, open questions 160
Recombinant production of eight human cytosolic aminotransferases and assessment of their potential involvement in glyoxylate metabolism 159
The advantages of being locked: assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes 158
A continuous kinetic assay for RNA-cleaving deoxyribozymes, exploiting ethidium bromide as an extrinsic fluorescent probe 156
Kinetic and thermodynamic characterization of the RNA-cleaving 8-17 deoxyribozyme 154
Allosteric regulation of tryptophan synthase: effects of pH, temperature and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate L-serine intermediates 153
Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase 148
Effect of pH and monovalent cations on the formation of quinonoid intermediates of the tryptophan synthase alpha2beta2 complex in solution and in the crystal 147
Discovery of a New, Recurrent Enzyme in Bacterial Phosphonate Degradation: (R)‑1-Hydroxy-2-aminoethylphosphonate Ammonia-lyase 146
A mutational analysis of the 8-17 deoxyribozyme core 142
Characterization of tryptophan and coenzyme luminescence in tryptophan synthase from Salmonella typhimurium 142
A genomic overview of pyridoxal-phosphate-dependent enzymes 142
Completing the folate biosynthesis pathway in Plasmodium falciparum: p-aminobenzoate is produced by a highly divergent promiscuous aminodeoxychorismate lyase 136
Biological catalysis: Lessons from the comparison of RNA and protein enzymes 136
Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism 135
A subfamily of PLP-dependent enzymes specialized in handling terminal amines 135
Human cytosolic transaminases: side activities and patterns of discrimination towards physiologically available alternative substrates 132
Prospects for antiviral ribozymes and deoxyribozymes 132
Kinetic characterization of the human O-phosphoethanolamine phospho-lyase reveals unconventional features of this specialized pyridoxal phosphate-dependent lyase 126
A core folding model for catalysis by the hammerhead ribozyme accounts for its extraordinary sensitivity to abasic Mutations 125
Time-resolved fluorescence of pyridoxal 5'-phosphate-containing enzymes: tryptophan synthase and O-acetylserine sulfhydrylase 125
Dissecting the hybridization of oligonucleotides to structured complementary sequences 124
Conformational changes and subunit communication in tryptophan synthase: effect of substrates and substrate analogs 123
The Microbial Degradation of Natural and Anthropogenic Phosphonates 121
Functional Properties of Immobilized Pyridoxal 5'-Phosphate-Dependent Enzymes Probed by Absorption Microspectrophotometry 121
Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization 121
Time resolved fluorescence of tryptophan synthase 119
Strict reaction and substrate specificity of AGXT2L1, the human O-phosphoethanolamine phospho-lyase 118
Local conformational changes in the 8–17 deoxyribozyme core induced by activating and inactivating divalent metal ions 117
The human phosphorylated pathway: a multienzyme metabolic assembly for l-serine biosynthesis 115
Time course of chemical and structural events in protein crystals measured by microspectrophotometry 115
The B6 database: a tool for the description and classification of vitamin B6-dependent enzymatic activities and of the corresponding protein families. 113
Insights into DNA catalysis from structural and functional studies of the 8-17 DNAzyme 112
Effects of monovalent cations on functional properties of the tryptophan synthase alpha2beta2 complex in solution and in the crystal 111
Ligand binding to human serine racemase: a spectroscopic and functional study 110
Pyridoxal 5’-Phosphate-Dependent Enzymes: Catalysis, Conformation and Genomics 109
Exploring and exploiting allostery: Models, evolution, and drug targeting 109
Using Steady-State Kinetics to Quantitate Substrate Selectivity and Specificity: A Case Study with Two Human Transaminases 109
Efficient and selective cleavage of RNA oligonucleotides by calix[4]arene-based synthetic metallonucleases 107
The limits of enzyme specificity and the evolution of metabolism 107
Serine racemase: a key player in neuron activity and in neuropathologies 104
How (and why) to revive a dead enzyme: the power of chemical rescue 102
Microspectrophotometric studies on single crystals of the tryptophan synthase alpha2beta2 complex demonstrate formation of enzyme-substrate intermediates 102
Use of intrinsic binding energy for catalysis by an RNA enzyme 100
Human serine racemase, a key enzyme in neurophysiology and neuropathologies 100
The putative Escherichia coli dehydrogenase YjhC metabolises two dehydrated forms of N-acetylneuraminate produced by some sialidases 99
Origins of the temperature dependence of hammerhead ribozyme catalysis 97
Enzyme catalysis: removing chemically "essential" residues by site-directed mutagenesis 97
Preferential activation of the 8-17 deoxyribozyme by Ca2+ ions. Evidence for the identity of 8-17 with the catalytic domain of the Mg5 deoxyribozyme 96
Regulation of human serine racemase activity and dynamics by halides, ATP and malonate 94
Monovalent cations affect dynamic and functional properties of the tryptophan synthase alpha2beta2 complex 89
Structural characterization of human O-phosphoethanolamine phospho-lyase 88
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation 88
Identification of the hammerhead ribozyme metal ion binding site responsible for rescue of the deleterious effect of a cleavage site phosphorothioate 86
Human serine racemase, a key enzyme in neurophysiology and neuropathologies 84
Structure-function relationships in the hammerhead ribozyme probed by base rescue 83
Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione 83
The metalloprotein YhcH is an anomerase providing N-acetylneuraminate aldolase with the open form of its substrate 83
Enzymes that make and enzymes that fix mistakes: Nit1 is a ‘repair’ amidase that hydrolyzes deaminated glutathione 81
Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases 76
Single crystal polarized absorption microspectrophotometry of aromatic L-aminoacid decarboxylase 76
The Substrate Versatility of Δ1-Pyrroline-5-carboxylate Reductase (ProC) from Escherichia coli 61
Regulation and dynamics of human serine racemase 48
Identification of the function of the metabolite repair enzyme Nit1: the story of a collaboration with Arthur Cooper 47
null 28
The Pyridoxal-5′-Phosphate-Dependent Enzymes of Mycobacterium tuberculosis 11
Totale 10.188
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Categoria #
all - tutte 34.795
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 34.795
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202114 0 0 0 0 0 0 0 0 0 0 0 14
2021/2022365 7 10 7 47 28 17 30 57 20 24 32 86
2022/20231.256 145 128 64 101 123 136 6 71 413 7 45 17
2023/2024510 27 56 9 24 40 97 50 41 21 29 48 68
2024/20251.888 102 105 143 83 188 255 81 102 169 186 149 325
2025/20264.349 332 594 514 421 535 202 455 187 475 304 183 147
Totale 10.188