IRIS
SCALVINI, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 2.241
AS - Asia 1.996
EU - Europa 1.765
SA - Sud America 243
AF - Africa 126
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.376
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Nazione #
US - Stati Uniti d'America 2.167
IT - Italia 754
SG - Singapore 728
CN - Cina 450
VN - Vietnam 371
BR - Brasile 188
IE - Irlanda 181
SE - Svezia 167
DE - Germania 147
HK - Hong Kong 140
BD - Bangladesh 88
FI - Finlandia 85
FR - Francia 85
ZA - Sudafrica 81
AT - Austria 73
NL - Olanda 67
RU - Federazione Russa 46
CA - Canada 45
IN - India 43
GB - Regno Unito 42
TR - Turchia 29
ES - Italia 22
ID - Indonesia 21
AR - Argentina 19
CI - Costa d'Avorio 19
MX - Messico 18
CZ - Repubblica Ceca 17
JP - Giappone 17
PL - Polonia 17
BE - Belgio 16
KR - Corea 16
TH - Thailandia 16
IQ - Iraq 15
MA - Marocco 10
PH - Filippine 9
KE - Kenya 8
CO - Colombia 7
JO - Giordania 7
MY - Malesia 7
PK - Pakistan 7
UA - Ucraina 7
VE - Venezuela 7
CL - Cile 6
HR - Croazia 6
LT - Lituania 6
PY - Paraguay 6
EC - Ecuador 5
SA - Arabia Saudita 5
UZ - Uzbekistan 5
HU - Ungheria 4
RO - Romania 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
SI - Slovenia 3
TN - Tunisia 3
TW - Taiwan 3
AL - Albania 2
AZ - Azerbaigian 2
CR - Costa Rica 2
CY - Cipro 2
DK - Danimarca 2
ET - Etiopia 2
GR - Grecia 2
HN - Honduras 2
IL - Israele 2
KG - Kirghizistan 2
MD - Moldavia 2
NO - Norvegia 2
PE - Perù 2
RS - Serbia 2
TT - Trinidad e Tobago 2
A1 - Anonimo 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
EG - Egitto 1
EU - Europa 1
GF - Guiana Francese 1
GT - Guatemala 1
GY - Guiana 1
IR - Iran 1
JM - Giamaica 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LC - Santa Lucia 1
LU - Lussemburgo 1
LY - Libia 1
NP - Nepal 1
PS - Palestinian Territory 1
QA - Qatar 1
SY - Repubblica araba siriana 1
UY - Uruguay 1
Totale 6.376
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Città #
Singapore 395
Ashburn 315
San Jose 232
Chandler 200
Parma 199
Dublin 176
Dallas 172
Santa Clara 151
Hong Kong 134
Ho Chi Minh City 114
Beijing 93
Ann Arbor 90
Johannesburg 78
Boardman 76
Hanoi 72
Los Angeles 66
New York 64
Vienna 63
Shanghai 55
Bologna 49
Munich 49
Milan 45
Hefei 36
Lauterbourg 36
Council Bluffs 34
Dearborn 32
Helsinki 28
Modena 28
Princeton 27
Frankfurt am Main 25
Wilmington 24
Columbus 22
Nanjing 20
Abidjan 19
Buffalo 19
Izmir 18
Seattle 18
São Paulo 18
Turku 18
Jakarta 17
Montreal 17
Dong Ket 16
Haiphong 16
Bremen 15
Brescia 15
Chicago 15
London 15
Seoul 15
Tokyo 15
Toronto 15
Moscow 14
Nuremberg 14
Da Nang 13
Stockholm 13
Warsaw 13
Amsterdam 12
Atlanta 12
Brussels 12
Fremont 12
Guangzhou 12
Reggio Emilia 12
Rome 12
The Dalles 12
Houston 11
Naples 11
Prata Di Pordenone 11
Düsseldorf 10
Hillsboro 10
Brno 9
Nanchang 9
Orem 9
Phoenix 9
Rio de Janeiro 9
Ardea 8
Brooklyn 8
Dhaka 8
Jinan 8
Mexico City 8
Shenyang 8
Verona 8
Weihai 8
Bangkok 7
Brasília 7
Concesio 7
Denver 7
Des Moines 7
Paris 7
Piacenza 7
Amman 6
Ankara 6
Baghdad 6
Bengaluru 6
Fairfield 6
Lubbock 6
Nairobi 6
Palermo 6
Biên Hòa 5
Bến Tre 5
Canneto sull'Oglio 5
Changsha 5
Totale 3.923
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Nome #
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines 277
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line 251
Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach 251
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties 217
Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice 217
A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine 208
N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition 207
Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats 201
Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors 191
Discovery of novel FGF trap small molecules endowed with anti-myeloma activity 181
Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria 181
N-Acylethanolamine Acid Amidase (NAAA): Mechanism of Palmitoylethanolamide Hydrolysis Revealed by Mechanistic Simulations 176
Chapter 9: Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activity 170
JAK3 Inhibitors: Covalent and Noncovalent Interactions of a Cyanamide Group Investigated by Multiscale Free-Energy Simulations 162
Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids 161
Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity 151
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists 147
Design and SAR Analysis of Covalent Inhibitors Driven by Hybrid QM/MM Simulations 141
The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment 137
Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit 136
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 136
Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL 133
Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase 133
Spirotetrahydroisoquinoline-Based Histone Deacetylase Inhibitors as New Antifibrotic Agents: Biological Evaluation in Human Fibroblasts from Bronchoalveolar Lavages of Idiopathic Pulmonary Fibrosis Patients 132
Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency 132
In silico drug discovery of melatonin receptor ligands with therapeutic potential 131
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands 130
Unbinding Kinetics of Muscarinic M3 Receptor Antagonists Explained by Metadynamics Simulations 128
New classes of potent heparanase inhibitors from ligand-based virtual screening 127
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity 126
Repurposing of drugs targeting yap-tead functions 126
Mechanistic Modeling of Lys745 Sulfonylation in EGFR C797S Reveals Chemical Determinants for Inhibitor Activity and Discriminates Reversible from Irreversible Agents 125
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 122
Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence 119
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 114
Fighting tertiary mutations in EGFR-driven lung-cancers: Current advances and future perspectives in medicinal chemistry 113
Synthesis and characterization of new bivalent agents as melatonin- and histamine h3-ligands. 105
New Coumarin derivatives as cholinergic and cannabinoid system modulators 97
Monoglyceride lipase: Structure and inhibitors 92
Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity 87
The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors 66
Dual targeting of EphAs and KDR axis hampers VEGF-induced angiogenesis and glioma stem cell replication 60
Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics 55
Phenotype Screening of an Azole-bisindole Chemical Library Identifies URB1483 as a New Antileishmanial Agent Devoid of Toxicity on Human Cells 54
Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor 47
N-Acylaminoethyltetrahydroquinolines: A new class of melatonin receptor ligands with in vivo activity on glioblastoma 13
New Vanillyl-capped HDAC inhibitors exhibit anti-tumor efficacy in neuroblastoma and glioblastoma cells 11
Application of Molecular Modelling studies to the search of novel approaches for neuroprotection and stem cells applications 1
Totale 6.478
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Categoria #
all - tutte 21.562
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.562
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202149 0 0 0 0 0 0 0 0 0 0 0 49
2021/2022240 11 15 12 35 37 4 20 19 22 7 9 49
2022/2023877 72 87 64 73 78 107 8 44 232 23 64 25
2023/2024420 33 22 24 18 33 77 27 53 21 21 37 54
2024/20251.319 39 56 81 88 141 140 76 98 155 115 125 205
2025/20263.070 225 267 389 294 353 161 290 116 379 284 189 123
Totale 6.478