IRIS
SCALVINI, Laura
 Distribuzione geografica
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Continente #
EU - Europa 975
NA - Nord America 773
AS - Asia 274
AF - Africa 18
Continente sconosciuto - Info sul continente non disponibili 2
Totale 2.042
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Nazione #
US - Stati Uniti d'America 770
IT - Italia 393
IE - Irlanda 178
CN - Cina 176
SE - Svezia 155
AT - Austria 62
FI - Finlandia 50
DE - Germania 44
SG - Singapore 36
FR - Francia 28
TR - Turchia 23
CI - Costa d'Avorio 18
VN - Vietnam 16
CZ - Repubblica Ceca 13
IN - India 13
BE - Belgio 12
GB - Regno Unito 12
ES - Italia 9
NL - Olanda 6
HK - Hong Kong 5
UA - Ucraina 4
CA - Canada 3
HR - Croazia 3
RO - Romania 3
JP - Giappone 2
TH - Thailandia 2
A1 - Anonimo 1
EU - Europa 1
LU - Lussemburgo 1
NO - Norvegia 1
PK - Pakistan 1
RU - Federazione Russa 1
Totale 2.042
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Città #
Chandler 200
Dublin 173
Parma 112
Ann Arbor 90
Ashburn 67
Vienna 59
Shanghai 47
Dearborn 32
New York 32
Beijing 30
Princeton 27
Wilmington 24
Bologna 21
Singapore 20
Nanjing 19
Abidjan 18
Izmir 18
Boardman 17
Dong Ket 16
Seattle 16
Bremen 15
Helsinki 14
Fremont 12
Los Angeles 12
Milan 12
Guangzhou 11
Prata Di Pordenone 11
Brno 9
Brussels 9
Modena 9
Nanchang 9
Ardea 8
Brescia 8
Jinan 8
Weihai 8
Des Moines 7
London 7
Piacenza 7
Shenyang 7
Düsseldorf 6
Rome 6
Canneto sull'Oglio 5
Fairfield 5
Hebei 5
Montegaldella 5
Norwalk 5
Paris 5
Pune 5
Verona 5
Ankara 4
Delhi 4
Hong Kong 4
Kunming 4
Naples 4
San Mateo 4
Atlanta 3
Belluno 3
Braunschweig 3
Cesano Maderno 3
Changsha 3
Dueville 3
Ferrara 3
Fuzhou 3
Genoa 3
Jiaxing 3
Leuven 3
Padova 3
Solignano 3
Tianjin 3
Zagreb 3
Alessandria 2
Amsterdam 2
Bangkok 2
Bilbao 2
Borås 2
Caprino Veronese 2
Casalnuovo di Napoli 2
Castiglione Olona 2
Council Bluffs 2
Ferrara di Monte Baldo 2
Fidenza 2
Frankfurt am Main 2
Grafing 2
Houston 2
Lanzhou 2
Lübeck 2
Madrid 2
Ospitaletto 2
Palermo 2
Pomigliano d'Arco 2
Quattro Castella 2
Redwood City 2
Reggio Emilia 2
Rende 2
Rocca Grimalda 2
Rockville 2
Romainville 2
Stockholm 2
Suzzara 2
Taranto 2
Totale 1.402
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Nome #
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines 132
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties 123
Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats 98
Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice 98
Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria 85
N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition 85
The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment 85
Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors 83
Chapter 9: Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activity 75
A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine 72
Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach 70
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists 70
Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids 68
N-Acylethanolamine Acid Amidase (NAAA): Mechanism of Palmitoylethanolamide Hydrolysis Revealed by Mechanistic Simulations 67
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands 66
Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit 60
Mechanistic Modeling of Lys745 Sulfonylation in EGFR C797S Reveals Chemical Determinants for Inhibitor Activity and Discriminates Reversible from Irreversible Agents 54
Design and SAR Analysis of Covalent Inhibitors Driven by Hybrid QM/MM Simulations 52
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 52
Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL 51
Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency 50
Monoglyceride lipase: Structure and inhibitors 49
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity 48
Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase 48
Synthesis and characterization of new bivalent agents as melatonin- and histamine h3-ligands. 45
Fighting tertiary mutations in EGFR-driven lung-cancers: Current advances and future perspectives in medicinal chemistry 45
Repurposing of drugs targeting yap-tead functions 44
New classes of potent heparanase inhibitors from ligand-based virtual screening 43
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 39
New Coumarin derivatives as cholinergic and cannabinoid system modulators 33
Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity 27
Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity 22
In silico drug discovery of melatonin receptor ligands with therapeutic potential 22
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 22
Unbinding Kinetics of Muscarinic M3 Receptor Antagonists Explained by Metadynamics Simulations 18
Phenotype Screening of an Azole-bisindole Chemical Library Identifies URB1483 as a New Antileishmanial Agent Devoid of Toxicity on Human Cells 12
Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence 4
Totale 2.117
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Categoria #
all - tutte 8.725
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 8.725
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020155 28 7 0 2 13 28 13 4 9 42 7 2
2020/2021278 1 0 32 10 26 41 30 22 40 17 10 49
2021/2022240 11 15 12 35 37 4 20 19 22 7 9 49
2022/2023877 72 87 64 73 78 107 8 44 232 23 64 25
2023/2024420 33 22 24 18 33 77 27 53 21 21 37 54
2024/202528 28 0 0 0 0 0 0 0 0 0 0 0
Totale 2.117