IRIS
SCALVINI, Laura
 Distribuzione geografica
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Continente #
EU - Europa 1.050
NA - Nord America 861
AS - Asia 431
AF - Africa 18
Continente sconosciuto - Info sul continente non disponibili 2
Totale 2.362
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Nazione #
US - Stati Uniti d'America 852
IT - Italia 444
CN - Cina 187
IE - Irlanda 179
SG - Singapore 176
SE - Svezia 155
AT - Austria 62
DE - Germania 53
FI - Finlandia 53
FR - Francia 30
TR - Turchia 23
CI - Costa d'Avorio 18
IN - India 18
GB - Regno Unito 16
VN - Vietnam 16
CZ - Repubblica Ceca 13
BE - Belgio 12
ES - Italia 10
CA - Canada 9
NL - Olanda 7
HK - Hong Kong 6
UA - Ucraina 4
HR - Croazia 3
RO - Romania 3
JP - Giappone 2
LT - Lituania 2
TH - Thailandia 2
A1 - Anonimo 1
EU - Europa 1
HU - Ungheria 1
LU - Lussemburgo 1
NO - Norvegia 1
PK - Pakistan 1
RU - Federazione Russa 1
Totale 2.362
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Città #
Chandler 200
Dublin 174
Singapore 149
Parma 125
Ann Arbor 90
Ashburn 69
Vienna 59
Boardman 56
Shanghai 50
New York 33
Dearborn 32
Beijing 30
Princeton 27
Wilmington 24
Bologna 21
Nanjing 19
Abidjan 18
Izmir 18
Dong Ket 16
Seattle 16
Bremen 15
Helsinki 15
Brescia 14
Milan 14
Modena 14
Los Angeles 13
Fremont 12
Guangzhou 11
Prata Di Pordenone 11
Santa Clara 11
Brno 9
Brussels 9
Nanchang 9
Ardea 8
Jinan 8
London 8
Weihai 8
Des Moines 7
Piacenza 7
Rome 7
Shenyang 7
Düsseldorf 6
Frankfurt am Main 6
Canneto sull'Oglio 5
Fairfield 5
Hebei 5
Hong Kong 5
Montegaldella 5
Munich 5
Norwalk 5
Ottawa 5
Paris 5
Pune 5
Verona 5
Ankara 4
Delhi 4
Kunming 4
Ludhiana 4
Naples 4
San Mateo 4
Amsterdam 3
Atlanta 3
Belluno 3
Braunschweig 3
Cesano Maderno 3
Changsha 3
Dueville 3
Ferrara 3
Fuzhou 3
Genoa 3
Jiaxing 3
Leuven 3
Padova 3
Solignano 3
Tianjin 3
Zagreb 3
Alessandria 2
Assago 2
Bangkok 2
Bergamo 2
Bilbao 2
Borås 2
Caprino Veronese 2
Casalgrande 2
Casalnuovo di Napoli 2
Castiglione Olona 2
Council Bluffs 2
Dallas 2
Ferrara di Monte Baldo 2
Fidenza 2
Grafing 2
Hangzhou 2
Houston 2
Lanzhou 2
Lübeck 2
Madrid 2
Marseille 2
Ospitaletto 2
Oulu 2
Palermo 2
Totale 1.630
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Nome #
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines 145
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties 130
Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats 108
Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice 107
Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria 94
The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment 93
N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition 91
Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors 90
Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach 87
Chapter 9: Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activity 82
A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine 78
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists 77
N-Acylethanolamine Acid Amidase (NAAA): Mechanism of Palmitoylethanolamide Hydrolysis Revealed by Mechanistic Simulations 76
Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids 75
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands 70
Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit 69
Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL 60
Design and SAR Analysis of Covalent Inhibitors Driven by Hybrid QM/MM Simulations 60
Mechanistic Modeling of Lys745 Sulfonylation in EGFR C797S Reveals Chemical Determinants for Inhibitor Activity and Discriminates Reversible from Irreversible Agents 58
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 57
Monoglyceride lipase: Structure and inhibitors 55
Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase 55
Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency 53
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity 53
Synthesis and characterization of new bivalent agents as melatonin- and histamine h3-ligands. 50
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 50
Repurposing of drugs targeting yap-tead functions 49
New classes of potent heparanase inhibitors from ligand-based virtual screening 49
Fighting tertiary mutations in EGFR-driven lung-cancers: Current advances and future perspectives in medicinal chemistry 49
New Coumarin derivatives as cholinergic and cannabinoid system modulators 38
Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity 34
Unbinding Kinetics of Muscarinic M3 Receptor Antagonists Explained by Metadynamics Simulations 33
Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity 30
In silico drug discovery of melatonin receptor ligands with therapeutic potential 28
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 28
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line 27
Discovery of novel FGF trap small molecules endowed with anti-myeloma activity 24
Phenotype Screening of an Azole-bisindole Chemical Library Identifies URB1483 as a New Antileishmanial Agent Devoid of Toxicity on Human Cells 15
Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence 12
Totale 2.439
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Categoria #
all - tutte 10.865
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 10.865
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020118 0 0 0 0 13 28 13 4 9 42 7 2
2020/2021278 1 0 32 10 26 41 30 22 40 17 10 49
2021/2022240 11 15 12 35 37 4 20 19 22 7 9 49
2022/2023877 72 87 64 73 78 107 8 44 232 23 64 25
2023/2024420 33 22 24 18 33 77 27 53 21 21 37 54
2024/2025350 39 56 81 88 86 0 0 0 0 0 0 0
Totale 2.439