IRIS
SCALVINI, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 2.543
AS - Asia 2.037
EU - Europa 1.862
SA - Sud America 259
AF - Africa 128
Continente sconosciuto - Info sul continente non disponibili 106
OC - Oceania 3
Totale 6.938
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Nazione #
US - Stati Uniti d'America 2.455
IT - Italia 837
SG - Singapore 729
CN - Cina 453
VN - Vietnam 373
BR - Brasile 195
IE - Irlanda 182
SE - Svezia 169
DE - Germania 148
HK - Hong Kong 143
BD - Bangladesh 106
FR - Francia 86
FI - Finlandia 85
ZA - Sudafrica 81
AT - Austria 73
NL - Olanda 67
CA - Canada 52
IN - India 47
RU - Federazione Russa 46
GB - Regno Unito 44
TR - Turchia 32
ES - Italia 28
ID - Indonesia 21
AR - Argentina 20
CI - Costa d'Avorio 19
MX - Messico 18
CZ - Repubblica Ceca 17
JP - Giappone 17
PL - Polonia 17
BE - Belgio 16
KR - Corea 16
TH - Thailandia 16
IQ - Iraq 15
VE - Venezuela 11
MA - Marocco 10
PH - Filippine 10
CO - Colombia 9
JO - Giordania 8
KE - Kenya 8
UA - Ucraina 8
CL - Cile 7
MY - Malesia 7
PK - Pakistan 7
EC - Ecuador 6
HR - Croazia 6
LT - Lituania 6
PY - Paraguay 6
SA - Arabia Saudita 5
UZ - Uzbekistan 5
AE - Emirati Arabi Uniti 4
CR - Costa Rica 4
HU - Ungheria 4
RO - Romania 4
AU - Australia 3
HN - Honduras 3
SI - Slovenia 3
TN - Tunisia 3
TW - Taiwan 3
AL - Albania 2
AZ - Azerbaigian 2
BB - Barbados 2
BH - Bahrain 2
CY - Cipro 2
DK - Danimarca 2
ET - Etiopia 2
GR - Grecia 2
IL - Israele 2
JM - Giamaica 2
KG - Kirghizistan 2
LB - Libano 2
MD - Moldavia 2
NO - Norvegia 2
PE - Perù 2
RS - Serbia 2
TT - Trinidad e Tobago 2
A1 - Anonimo 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BY - Bielorussia 1
CG - Congo 1
DO - Repubblica Dominicana 1
EG - Egitto 1
EU - Europa 1
GF - Guiana Francese 1
GT - Guatemala 1
GY - Guiana 1
IR - Iran 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
LU - Lussemburgo 1
LY - Libia 1
NP - Nepal 1
OM - Oman 1
PR - Porto Rico 1
PS - Palestinian Territory 1
QA - Qatar 1
SC - Seychelles 1
SV - El Salvador 1
Totale 6.832
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Città #
Singapore 395
Ashburn 327
San Jose 315
Parma 214
Chandler 200
Santa Clara 195
Dublin 176
Dallas 172
Hong Kong 137
Ho Chi Minh City 116
Council Bluffs 96
Beijing 94
Ann Arbor 90
Johannesburg 78
Boardman 76
Hanoi 72
Los Angeles 69
New York 67
Vienna 63
Milan 61
Shanghai 56
Bologna 55
Munich 49
Hefei 36
Lauterbourg 36
Dearborn 32
Modena 29
Helsinki 28
Princeton 27
Frankfurt am Main 25
Wilmington 24
Rome 23
Columbus 22
Buffalo 21
Nanjing 20
Abidjan 19
Chicago 19
Montreal 19
Izmir 18
Seattle 18
São Paulo 18
Turku 18
Jakarta 17
Dong Ket 16
Haiphong 16
London 16
Bremen 15
Brescia 15
Seoul 15
Tokyo 15
Toronto 15
Moscow 14
Nuremberg 14
Da Nang 13
Reggio Emilia 13
Stockholm 13
The Dalles 13
Warsaw 13
Amsterdam 12
Atlanta 12
Brussels 12
Fremont 12
Guangzhou 12
Phoenix 12
Hillsboro 11
Houston 11
Naples 11
Prata Di Pordenone 11
Bengaluru 10
Düsseldorf 10
Madrid 10
Orem 10
Brno 9
Brooklyn 9
Nanchang 9
Rio de Janeiro 9
Ardea 8
Brasília 8
Dhaka 8
Jinan 8
Mexico City 8
Paris 8
Shenyang 8
Verona 8
Weihai 8
Amman 7
Bangkok 7
Concesio 7
Denver 7
Des Moines 7
Piacenza 7
Ankara 6
Baghdad 6
Fairfield 6
Lubbock 6
Nairobi 6
Ottawa 6
Palermo 6
Turin 6
Biên Hòa 5
Totale 4.217
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Nome #
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines 284
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line 266
Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach 261
Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice 223
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties 222
Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats 221
N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition 215
A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine 213
Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors 195
Discovery of novel FGF trap small molecules endowed with anti-myeloma activity 191
Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria 184
N-Acylethanolamine Acid Amidase (NAAA): Mechanism of Palmitoylethanolamide Hydrolysis Revealed by Mechanistic Simulations 181
Chapter 9: Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activity 178
JAK3 Inhibitors: Covalent and Noncovalent Interactions of a Cyanamide Group Investigated by Multiscale Free-Energy Simulations 172
Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids 170
Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity 159
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands 159
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists 151
Design and SAR Analysis of Covalent Inhibitors Driven by Hybrid QM/MM Simulations 144
Spirotetrahydroisoquinoline-Based Histone Deacetylase Inhibitors as New Antifibrotic Agents: Biological Evaluation in Human Fibroblasts from Bronchoalveolar Lavages of Idiopathic Pulmonary Fibrosis Patients 142
Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency 140
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 140
Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit 139
The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment 139
Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase 139
Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL 137
Unbinding Kinetics of Muscarinic M3 Receptor Antagonists Explained by Metadynamics Simulations 136
In silico drug discovery of melatonin receptor ligands with therapeutic potential 135
Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence 132
Repurposing of drugs targeting yap-tead functions 132
New classes of potent heparanase inhibitors from ligand-based virtual screening 130
Mechanistic Modeling of Lys745 Sulfonylation in EGFR C797S Reveals Chemical Determinants for Inhibitor Activity and Discriminates Reversible from Irreversible Agents 130
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity 127
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 126
Fighting tertiary mutations in EGFR-driven lung-cancers: Current advances and future perspectives in medicinal chemistry 120
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 117
The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors 113
Synthesis and characterization of new bivalent agents as melatonin- and histamine h3-ligands. 107
New Coumarin derivatives as cholinergic and cannabinoid system modulators 101
Monoglyceride lipase: Structure and inhibitors 97
Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity 90
Dual targeting of EphAs and KDR axis hampers VEGF-induced angiogenesis and glioma stem cell replication 81
Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor 73
Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics 66
Phenotype Screening of an Azole-bisindole Chemical Library Identifies URB1483 as a New Antileishmanial Agent Devoid of Toxicity on Human Cells 59
Targeting the YAP:TEAD domain through fluorescence-anisotropy displacement assay 34
N-Acylaminoethyltetrahydroquinolines: A new class of melatonin receptor ligands with in vivo activity on glioblastoma 28
New Vanillyl-capped HDAC inhibitors exhibit anti-tumor efficacy in neuroblastoma and glioblastoma cells 20
Application of Molecular Modelling studies to the search of novel approaches for neuroprotection and stem cells applications 19
Totale 6.938
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Categoria #
all - tutte 23.778
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 23.778
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022214 0 0 12 35 37 4 20 19 22 7 9 49
2022/2023877 72 87 64 73 78 107 8 44 232 23 64 25
2023/2024420 33 22 24 18 33 77 27 53 21 21 37 54
2024/20251.319 39 56 81 88 141 140 76 98 155 115 125 205
2025/20263.112 225 267 389 294 353 161 290 116 379 284 189 165
2026/2027418 123 190 105 0 0 0 0 0 0 0 0 0
Totale 6.938