IRIS
SCALVINI, Laura
 Distribuzione geografica
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Continente #
NA - Nord America 2.042
AS - Asia 1.925
EU - Europa 1.695
SA - Sud America 243
AF - Africa 126
Continente sconosciuto - Info sul continente non disponibili 2
OC - Oceania 2
Totale 6.035
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Nazione #
US - Stati Uniti d'America 1.982
SG - Singapore 722
IT - Italia 694
CN - Cina 446
VN - Vietnam 371
BR - Brasile 188
IE - Irlanda 181
SE - Svezia 167
DE - Germania 146
HK - Hong Kong 139
FR - Francia 85
ZA - Sudafrica 81
FI - Finlandia 77
AT - Austria 73
NL - Olanda 67
RU - Federazione Russa 46
IN - India 43
GB - Regno Unito 41
CA - Canada 35
BD - Bangladesh 30
TR - Turchia 29
ES - Italia 22
ID - Indonesia 21
AR - Argentina 19
CI - Costa d'Avorio 19
CZ - Repubblica Ceca 17
JP - Giappone 17
MX - Messico 17
PL - Polonia 17
BE - Belgio 16
KR - Corea 16
IQ - Iraq 15
TH - Thailandia 15
MA - Marocco 10
PH - Filippine 9
KE - Kenya 8
CO - Colombia 7
JO - Giordania 7
MY - Malesia 7
PK - Pakistan 7
UA - Ucraina 7
VE - Venezuela 7
CL - Cile 6
HR - Croazia 6
LT - Lituania 6
PY - Paraguay 6
EC - Ecuador 5
SA - Arabia Saudita 5
UZ - Uzbekistan 5
HU - Ungheria 4
RO - Romania 4
AE - Emirati Arabi Uniti 3
SI - Slovenia 3
TN - Tunisia 3
TW - Taiwan 3
AL - Albania 2
AU - Australia 2
AZ - Azerbaigian 2
CR - Costa Rica 2
CY - Cipro 2
DK - Danimarca 2
ET - Etiopia 2
GR - Grecia 2
HN - Honduras 2
IL - Israele 2
KG - Kirghizistan 2
MD - Moldavia 2
NO - Norvegia 2
PE - Perù 2
RS - Serbia 2
A1 - Anonimo 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
EG - Egitto 1
EU - Europa 1
GF - Guiana Francese 1
GT - Guatemala 1
GY - Guiana 1
IR - Iran 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
LY - Libia 1
NP - Nepal 1
PS - Palestinian Territory 1
QA - Qatar 1
SY - Repubblica araba siriana 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
Totale 6.035
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Città #
Singapore 393
Ashburn 301
Chandler 200
Parma 198
Dublin 176
San Jose 175
Dallas 168
Santa Clara 142
Hong Kong 133
Ho Chi Minh City 114
Beijing 91
Ann Arbor 90
Johannesburg 78
Hanoi 72
Boardman 67
Vienna 63
Los Angeles 57
Shanghai 55
New York 52
Munich 49
Bologna 43
Milan 38
Hefei 36
Lauterbourg 36
Dearborn 32
Modena 28
Princeton 27
Council Bluffs 26
Frankfurt am Main 25
Wilmington 24
Columbus 21
Helsinki 21
Nanjing 20
Abidjan 19
Izmir 18
Seattle 18
São Paulo 18
Turku 18
Jakarta 17
Buffalo 16
Dong Ket 16
Haiphong 16
Bremen 15
Seoul 15
Tokyo 15
Brescia 14
Chicago 14
London 14
Montreal 14
Moscow 14
Nuremberg 14
Da Nang 13
Stockholm 13
Warsaw 13
Amsterdam 12
Atlanta 12
Brussels 12
Fremont 12
Guangzhou 12
Reggio Emilia 12
The Dalles 12
Prata Di Pordenone 11
Düsseldorf 10
Houston 10
Naples 10
Toronto 10
Brno 9
Nanchang 9
Rio de Janeiro 9
Ardea 8
Dhaka 8
Jinan 8
Phoenix 8
Rome 8
Shenyang 8
Verona 8
Weihai 8
Bangkok 7
Brasília 7
Brooklyn 7
Concesio 7
Denver 7
Des Moines 7
Mexico City 7
Orem 7
Paris 7
Piacenza 7
Amman 6
Ankara 6
Baghdad 6
Bengaluru 6
Lubbock 6
Nairobi 6
Biên Hòa 5
Bến Tre 5
Canneto sull'Oglio 5
Changsha 5
Chongqing 5
Delhi 5
Fairfield 5
Totale 3.742
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Nome #
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines 268
Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach 240
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line 232
Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice 215
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties 214
A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine 204
Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats 198
N-Acylethanolamine Acid Amidase (NAAA): Structure, Function, and Inhibition 197
Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors 186
Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria 180
N-Acylethanolamine Acid Amidase (NAAA): Mechanism of Palmitoylethanolamide Hydrolysis Revealed by Mechanistic Simulations 174
Discovery of novel FGF trap small molecules endowed with anti-myeloma activity 167
Chapter 9: Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activity 167
JAK3 Inhibitors: Covalent and Noncovalent Interactions of a Cyanamide Group Investigated by Multiscale Free-Energy Simulations 153
Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids 153
Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity 149
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists 145
Design and SAR Analysis of Covalent Inhibitors Driven by Hybrid QM/MM Simulations 138
The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment 137
Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit 135
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 133
Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL 131
Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase 131
Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency 127
Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands 125
Unbinding Kinetics of Muscarinic M3 Receptor Antagonists Explained by Metadynamics Simulations 124
Repurposing of drugs targeting yap-tead functions 124
New classes of potent heparanase inhibitors from ligand-based virtual screening 124
Mechanistic Modeling of Lys745 Sulfonylation in EGFR C797S Reveals Chemical Determinants for Inhibitor Activity and Discriminates Reversible from Irreversible Agents 124
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth 120
In silico drug discovery of melatonin receptor ligands with therapeutic potential 113
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 111
Fighting tertiary mutations in EGFR-driven lung-cancers: Current advances and future perspectives in medicinal chemistry 108
Novel Benzazole Derivatives Endowed with Potent Antiheparanase Activity 107
Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence 101
Synthesis and characterization of new bivalent agents as melatonin- and histamine h3-ligands. 101
Spirotetrahydroisoquinoline-Based Histone Deacetylase Inhibitors as New Antifibrotic Agents: Biological Evaluation in Human Fibroblasts from Bronchoalveolar Lavages of Idiopathic Pulmonary Fibrosis Patients 99
New Coumarin derivatives as cholinergic and cannabinoid system modulators 97
Monoglyceride lipase: Structure and inhibitors 92
Novel Symmetrical Benzazolyl Derivatives Endowed with Potent Anti-Heparanase Activity 81
Phenotype Screening of an Azole-bisindole Chemical Library Identifies URB1483 as a New Antileishmanial Agent Devoid of Toxicity on Human Cells 53
Dual targeting of EphAs and KDR axis hampers VEGF-induced angiogenesis and glioma stem cell replication 47
Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics 46
Reversing TGF-β1-induced fibrotic phenotype in human lung fibroblasts using a PROTAC tool derived from an indoline-based HDAC6 inhibitor 35
The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors 28
Totale 6.134
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Categoria #
all - tutte 20.126
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.126
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202176 0 0 0 0 0 0 0 0 0 17 10 49
2021/2022240 11 15 12 35 37 4 20 19 22 7 9 49
2022/2023877 72 87 64 73 78 107 8 44 232 23 64 25
2023/2024420 33 22 24 18 33 77 27 53 21 21 37 54
2024/20251.319 39 56 81 88 141 140 76 98 155 115 125 205
2025/20262.726 225 267 389 294 353 161 290 116 379 252 0 0
Totale 6.134