SCALVINI, Laura
SCALVINI, Laura
Dipartimento di Scienze degli Alimenti e del Farmaco
A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine
2021-01-01 Ferlenghi, F; Scalvini, L; Vacondio, F; Castelli, R; Bozza, N; Marseglia, G; Rivara, S; Lodola, A; La Monica, S; Minari, R; Petronini, Pg; Alfieri, R; Tiseo, M; Mor, M.
Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats
2015-01-01 Vacondio, Federica; Bassi, Michele; Silva, Claudia; Castelli, Riccardo; Carmi, Caterina; Scalvini, Laura; Lodola, Alessio; Vivo, Valentina; Flammini, Lisa; Barocelli, Elisabetta; Mor, Marco; Rivara, Silvia
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines
2020-01-01 Castelli, Riccardo; Scalvini, Laura; Vacondio, Federica; Lodola, Alessio; Anselmi, Mattia; Vezzosi, Stefano; Carmi, Caterina; Bassi, Michele; Ferlenghi, Francesca; Rivara, Silvia; Moller Ingvar, R.; Rand Kasper, D.; Daglian, Jennifer; Wei, Don; Dotsey Emmanuel, Y.; Ahmed, Faizy; Jung, Kwang-Mook; Stella, Nephi; Singh, Simar; Mor, Marco; Piomelli, Daniele.
Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence
2024-01-01 Bedini, A.; Elisi, G. M.; Fanini, F.; Retini, M.; Scalvini, L.; Pasquini, S.; Contri, C.; Varani, K.; Spadoni, G.; Mor, M.; Vincenzi, F.; Rivara, S.
Chapter 9: Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activity
2021-01-01 Scalvini, L.; Rivara, S.; Jung, K. -M.; Mor, M.; Piomelli, D.
Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria
2020-01-01 Elisi, GIAN MARCO; Bedini, Annalida; Scalvini, Laura; Carmi, Caterina; Bartolucci, Silvia; Lucini, Valeria; Scaglione, Francesco; Mor, Marco; Rivara, Silvia; Spadoni, Gilberto
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists
2015-01-01 Callegari, Donatella; Pala, Daniele; Scalvini, Laura; Tognolini, Massimiliano; Incerti, Matteo; Rivara, Silvia; Mor, Marco; Lodola, Alessio
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth
2018-01-01 Saxena, P; Severi, L; Santucci, M; Taddia, ; Ferrari, S; Luciani, R; Marverti, G; Marraccini, C; Tondi, D; Mor, M; Scalvini, L; Vitiello, S; Losi, L; Fonda, S; Pacifico, S; Guerrini, R; D'Arca, D; Ponterini, G; Costi, Mp
Design and SAR Analysis of Covalent Inhibitors Driven by Hybrid QM/MM Simulations
2020-01-01 Lodola, A.; Callegari, D.; Scalvini, L.; Rivara, S.; Mor, M.
Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase
2021-01-01 Ghidini, A.; Scalvini, L.; Palese, F.; Lodola, A.; Mor, M.; Piomelli, D.
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line
2024-01-01 Guidetti, Lorenzo; Castelli, Riccardo; Zappia, Alfonso; Ferrari, Francesca Romana; Giorgio, Carmine; Barocelli, Elisabetta; Pagliaro, Luca; Vento, Federica; Roti, Giovanni; Scalvini, Laura; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano
Discovery of novel FGF trap small molecules endowed with anti-myeloma activity
2024-01-01 Taranto, Sara; Castelli, Riccardo; Marseglia, Giuseppe; Scalvini, Laura; Vacondio, Federica; Gianoncelli, Alessandra; Ribaudo, Giovanni; Faletti, Jessica; Gazzaroli, Giorgia; Rocca, Edoardo; Ronca, Roberto; Rusnati, Marco; Sacco, Antonio; Roccaro, Aldo Maria; Presta, Marco; Mor, Marco; Giacomini, Arianna; Rivara, Silvia
Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice
2020-01-01 Ferlenghi, F.; Castelli, R.; Scalvini, L.; Giorgio, C.; Corrado, M.; Tognolini, M.; Mor, M.; Lodola, A.; Vacondio, F.
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents
2016-01-01 Montanari, Serena; Scalvini, Laura; Bartolini, Manuela; Belluti, Federica; Gobbi, Silvia; Andrisano, Vincenza; Ligresti, Alessia; Di Marzo, Vincenzo; Rivara, Silvia; Mor, Marco; Bisi, Alessandra; Rampa, Angela
Fighting tertiary mutations in EGFR-driven lung-cancers: Current advances and future perspectives in medicinal chemistry
2021-01-01 Scalvini, Laura; Castelli, Riccardo; La Monica, Silvia; Tiseo, Marcello; Alfieri, Roberta
Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors
2022-01-01 Elisi, GIAN MARCO; Scalvini, Laura; Lodola, Alessio; Mor, Marco; Rivara, Silvia
Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL
2016-01-01 Scalvini, Laura; Vacondio, Federica; Bassi, Michele; Pala, Daniele; Lodola, Alessio; Rivara, Silvia; Jung, Kwang Mook; Piomelli, Daniele; Mor, Marco
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library
2022-01-01 Lauriola, Angela; Uliassi, Elisa; Santucci, Matteo; Laura Bolognesi, Maria; Mor, Marco; Scalvini, Laura; Elisi, GIAN MARCO; Gozzi, Gaia; Tagliazucchi, Lorenzo; Marverti, Gaetano; Ferrari, Stefania; Losi, Lorena; D’Arca, Domenico; Paola Costi, Maria
Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit
2018-01-01 Spadoni, G; Bedini, A; Furiassi, L; Mari, M; Mor, M; Scalvini, L; Lodola, A; Ghidini, Andrea; Lucini, V; Dugnani, S; Scaglione, F; Piomelli, D; Jung, Km; Supuran, Ct; Lucarini, L; Durante, M; Sgambellone, S; Masini, E; Rivara, S.
In silico drug discovery of melatonin receptor ligands with therapeutic potential
2022-01-01 Elisi, G. M.; Scalvini, L.; Lodola, A.; Bedini, A.; Spadoni, G.; Rivara, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine | 1-gen-2021 | Ferlenghi, F; Scalvini, L; Vacondio, F; Castelli, R; Bozza, N; Marseglia, G; Rivara, S; Lodola, A; La Monica, S; Minari, R; Petronini, Pg; Alfieri, R; Tiseo, M; Mor, M. | |
| Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats | 1-gen-2015 | Vacondio, Federica; Bassi, Michele; Silva, Claudia; Castelli, Riccardo; Carmi, Caterina; Scalvini, Laura; Lodola, Alessio; Vivo, Valentina; Flammini, Lisa; Barocelli, Elisabetta; Mor, Marco; Rivara, Silvia | |
| Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines | 1-gen-2020 | Castelli, Riccardo; Scalvini, Laura; Vacondio, Federica; Lodola, Alessio; Anselmi, Mattia; Vezzosi, Stefano; Carmi, Caterina; Bassi, Michele; Ferlenghi, Francesca; Rivara, Silvia; Moller Ingvar, R.; Rand Kasper, D.; Daglian, Jennifer; Wei, Don; Dotsey Emmanuel, Y.; Ahmed, Faizy; Jung, Kwang-Mook; Stella, Nephi; Singh, Simar; Mor, Marco; Piomelli, Daniele. | |
| Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence | 1-gen-2024 | Bedini, A.; Elisi, G. M.; Fanini, F.; Retini, M.; Scalvini, L.; Pasquini, S.; Contri, C.; Varani, K.; Spadoni, G.; Mor, M.; Vincenzi, F.; Rivara, S. | |
| Chapter 9: Natural and Synthetic Agents That Target Intracellular Monoacylglycerol Lipase (MGL) Activity | 1-gen-2021 | Scalvini, L.; Rivara, S.; Jung, K. -M.; Mor, M.; Piomelli, D. | |
| Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria | 1-gen-2020 | Elisi, GIAN MARCO; Bedini, Annalida; Scalvini, Laura; Carmi, Caterina; Bartolucci, Silvia; Lucini, Valeria; Scaglione, Francesco; Mor, Marco; Rivara, Silvia; Spadoni, Gilberto | |
| Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists | 1-gen-2015 | Callegari, Donatella; Pala, Daniele; Scalvini, Laura; Tognolini, Massimiliano; Incerti, Matteo; Rivara, Silvia; Mor, Marco; Lodola, Alessio | |
| Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth | 1-gen-2018 | Saxena, P; Severi, L; Santucci, M; Taddia, ; Ferrari, S; Luciani, R; Marverti, G; Marraccini, C; Tondi, D; Mor, M; Scalvini, L; Vitiello, S; Losi, L; Fonda, S; Pacifico, S; Guerrini, R; D'Arca, D; Ponterini, G; Costi, Mp | |
| Design and SAR Analysis of Covalent Inhibitors Driven by Hybrid QM/MM Simulations | 1-gen-2020 | Lodola, A.; Callegari, D.; Scalvini, L.; Rivara, S.; Mor, M. | |
| Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase | 1-gen-2021 | Ghidini, A.; Scalvini, L.; Palese, F.; Lodola, A.; Mor, M.; Piomelli, D. | |
| Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line | 1-gen-2024 | Guidetti, Lorenzo; Castelli, Riccardo; Zappia, Alfonso; Ferrari, Francesca Romana; Giorgio, Carmine; Barocelli, Elisabetta; Pagliaro, Luca; Vento, Federica; Roti, Giovanni; Scalvini, Laura; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano | |
| Discovery of novel FGF trap small molecules endowed with anti-myeloma activity | 1-gen-2024 | Taranto, Sara; Castelli, Riccardo; Marseglia, Giuseppe; Scalvini, Laura; Vacondio, Federica; Gianoncelli, Alessandra; Ribaudo, Giovanni; Faletti, Jessica; Gazzaroli, Giorgia; Rocca, Edoardo; Ronca, Roberto; Rusnati, Marco; Sacco, Antonio; Roccaro, Aldo Maria; Presta, Marco; Mor, Marco; Giacomini, Arianna; Rivara, Silvia | |
| Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice | 1-gen-2020 | Ferlenghi, F.; Castelli, R.; Scalvini, L.; Giorgio, C.; Corrado, M.; Tognolini, M.; Mor, M.; Lodola, A.; Vacondio, F. | |
| Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents | 1-gen-2016 | Montanari, Serena; Scalvini, Laura; Bartolini, Manuela; Belluti, Federica; Gobbi, Silvia; Andrisano, Vincenza; Ligresti, Alessia; Di Marzo, Vincenzo; Rivara, Silvia; Mor, Marco; Bisi, Alessandra; Rampa, Angela | |
| Fighting tertiary mutations in EGFR-driven lung-cancers: Current advances and future perspectives in medicinal chemistry | 1-gen-2021 | Scalvini, Laura; Castelli, Riccardo; La Monica, Silvia; Tiseo, Marcello; Alfieri, Roberta | |
| Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors | 1-gen-2022 | Elisi, GIAN MARCO; Scalvini, Laura; Lodola, Alessio; Mor, Marco; Rivara, Silvia | |
| Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL | 1-gen-2016 | Scalvini, Laura; Vacondio, Federica; Bassi, Michele; Pala, Daniele; Lodola, Alessio; Rivara, Silvia; Jung, Kwang Mook; Piomelli, Daniele; Mor, Marco | |
| Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library | 1-gen-2022 | Lauriola, Angela; Uliassi, Elisa; Santucci, Matteo; Laura Bolognesi, Maria; Mor, Marco; Scalvini, Laura; Elisi, GIAN MARCO; Gozzi, Gaia; Tagliazucchi, Lorenzo; Marverti, Gaetano; Ferrari, Stefania; Losi, Lorena; D’Arca, Domenico; Paola Costi, Maria | |
| Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit | 1-gen-2018 | Spadoni, G; Bedini, A; Furiassi, L; Mari, M; Mor, M; Scalvini, L; Lodola, A; Ghidini, Andrea; Lucini, V; Dugnani, S; Scaglione, F; Piomelli, D; Jung, Km; Supuran, Ct; Lucarini, L; Durante, M; Sgambellone, S; Masini, E; Rivara, S. | |
| In silico drug discovery of melatonin receptor ligands with therapeutic potential | 1-gen-2022 | Elisi, G. M.; Scalvini, L.; Lodola, A.; Bedini, A.; Spadoni, G.; Rivara, S. |