IRIS
BRUNO, Stefano
 Distribuzione geografica
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Continente #
NA - Nord America 7.234
AS - Asia 5.836
EU - Europa 4.379
SA - Sud America 836
Continente sconosciuto - Info sul continente non disponibili 344
AF - Africa 314
OC - Oceania 9
Totale 18.952
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Nazione #
US - Stati Uniti d'America 7.029
SG - Singapore 2.121
CN - Cina 1.516
IT - Italia 998
VN - Vietnam 807
BR - Brasile 647
IE - Irlanda 603
SE - Svezia 566
FI - Finlandia 545
DE - Germania 474
HK - Hong Kong 445
BD - Bangladesh 278
UA - Ucraina 241
FR - Francia 198
ZA - Sudafrica 191
NL - Olanda 178
TR - Turchia 170
GB - Regno Unito 136
AT - Austria 114
CA - Canada 114
IN - India 113
RU - Federazione Russa 98
AR - Argentina 77
JP - Giappone 51
MX - Messico 48
KR - Corea 46
IQ - Iraq 45
ID - Indonesia 43
PL - Polonia 35
CI - Costa d'Avorio 34
PK - Pakistan 33
EC - Ecuador 32
ES - Italia 32
CZ - Repubblica Ceca 28
BE - Belgio 23
PH - Filippine 22
CO - Colombia 21
RO - Romania 20
TH - Thailandia 18
LT - Lituania 17
EG - Egitto 16
TN - Tunisia 15
UZ - Uzbekistan 15
VE - Venezuela 15
JO - Giordania 14
MA - Marocco 14
MY - Malesia 14
CL - Cile 13
CH - Svizzera 12
CR - Costa Rica 12
KE - Kenya 12
TW - Taiwan 12
HN - Honduras 11
PT - Portogallo 11
AE - Emirati Arabi Uniti 10
PY - Paraguay 10
SA - Arabia Saudita 10
IL - Israele 9
NP - Nepal 9
UY - Uruguay 8
LB - Libano 7
BY - Bielorussia 6
DZ - Algeria 6
ET - Etiopia 6
LU - Lussemburgo 6
PE - Perù 6
AU - Australia 5
BO - Bolivia 5
HR - Croazia 5
MD - Moldavia 5
SN - Senegal 5
BG - Bulgaria 4
IR - Iran 4
JM - Giamaica 4
KZ - Kazakistan 4
RS - Serbia 4
TT - Trinidad e Tobago 4
AL - Albania 3
AZ - Azerbaigian 3
DK - Danimarca 3
GE - Georgia 3
KG - Kirghizistan 3
NG - Nigeria 3
NZ - Nuova Zelanda 3
SC - Seychelles 3
DO - Repubblica Dominicana 2
EE - Estonia 2
EU - Europa 2
GA - Gabon 2
GR - Grecia 2
GT - Guatemala 2
PA - Panama 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
Totale 18.583
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Città #
Singapore 1.068
Ashburn 876
San Jose 734
Chandler 609
Dublin 599
Santa Clara 550
Dallas 442
Hong Kong 428
Beijing 352
Parma 301
Jacksonville 276
Council Bluffs 275
Dearborn 257
Ho Chi Minh City 225
Ann Arbor 219
Boardman 206
Munich 200
Hanoi 197
New York 196
Johannesburg 175
Nanjing 156
Los Angeles 145
Izmir 122
Lauterbourg 122
Princeton 115
Hefei 103
Shanghai 102
Helsinki 99
Vienna 95
Buffalo 82
Milan 75
Wilmington 70
San Mateo 65
Bremen 63
Columbus 59
Toronto 58
São Paulo 57
Shenyang 56
Chicago 53
Moscow 53
The Dalles 50
Tokyo 42
Guangzhou 41
Nanchang 39
Jinan 38
Piacenza 38
Da Nang 37
Kunming 36
Seoul 36
Abidjan 34
Bologna 34
Des Moines 33
Hebei 33
Rome 32
Turku 30
London 29
Tianjin 29
Haiphong 28
Bangalore 27
Warsaw 27
Jakarta 26
Changsha 25
Marseille 25
Orem 25
Seattle 24
Frankfurt am Main 23
Houston 21
Baghdad 20
Jiaxing 20
Woodbridge 20
Nuremberg 19
Brooklyn 18
Brussels 18
Brescia 17
Montreal 17
Rio de Janeiro 17
Stockholm 17
Belo Horizonte 16
Brno 16
Modena 16
Phoenix 16
Atlanta 15
Falls Church 15
Mexico City 15
Tashkent 15
Biên Hòa 14
Denver 14
Fidenza 14
Haikou 14
Hangzhou 14
Mumbai 14
Fremont 13
Norwalk 13
Amman 12
Boston 12
San Francisco 12
Ankara 11
Can Tho 11
Grafing 11
Guayaquil 11
Totale 11.294
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Nome #
High and low oxygen affinity conformations of T state hemoglobin 265
Targeting the Eph/ephrin system as anti-inflammatory strategy in IBD 254
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP 246
Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin 241
A phosphoserine phosphatase variant present in the brain of Alzheimer's disease patients favors nuclear mistargeting 237
Ligand migration in non symbiotic hemoglobin AHb1 from Arabidopsis thaliana 236
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase 208
L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase 199
From hemoglobin allostery to hemoglobin-based oxygen carriers 198
ATP binding to human serine racemase is cooperative and modulated by glycine 196
Functional Characterization of Heme Proteins Encapsulated in Wet Nanoporous Silica Gels 194
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme 193
Augmentation therapy with alpha 1-antitrypsin: present and future of production, formulation, and delivery 193
Nebulizers effectiveness on pulmonary delivery of alpha-1 antitrypsin 190
A Photoactive Supramolecular Complex Targeting PD-L1 Reveals a Weak Correlation between Photoactivation Efficiency and Receptor Expression Levels in Non-Small-Cell Lung Cancer Tumor Models 188
CO rebinding kinetics and molecular dynamics simulations highlight dynamic regulation of internal cavities in human cytoglobin 185
Mycobacterial and human ferrous nitrobindins: Spectroscopic and reactivity properties 182
Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor 181
Biocatalysis in a confined environment. Lessons from enzymes immobilized in wet, nanoporous silica gels 178
A photosensitizing fusion protein with targeting capabilities 177
Genetically Encoded Biosensors for the Fluorescence Detection of O2 and Reactive O2 Species 176
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels 176
Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants 173
The Energy Landscape of Human Serine Racemase 170
Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus 170
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 169
Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95 168
Kinetic and dynamical properties of truncated hemoglobins of the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 167
Structural and functional properties of Antarctic fish cytoglobins-1: cold-reactivity in multi-ligand reactions 166
Nitric Oxide Sensing by a Blue Fluorescent Protein 165
Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana 165
Biochemical platform for the identification of adverse effects triggered by free hemoglobin in guinea pigs 164
Characterization of ligand migration mechanisms inside haemoglobins from the analysis of geminate rebinding kinetics 164
CO rebinding kinetics to high and low affinity T state hemoglobin encapsulated in silica gels 163
Enhanced geminate ligand rebinding upon photo-dissociation of silica gels-embedded myoglobin-CO 159
The Reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is Controlled by the Distal HisE7 and Internal Hydrophobic Cavities 159
Time-resolved methods in biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis 159
Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes 157
Mass spectrometry-based proteomic strategy for ecchymotic skin examination in forensic pathology 155
Human serine racemase is nitrosylated at multiple sites 155
Cold-Adaptation Signatures in the Ligand Rebinding Kinetics to the Truncated Hemoglobin of the Antarctic Bacterium Pseudoalteromonas haloplanktis TAC125 154
Correlation of protein functional properties in the crystal and in solution: the case study of T state hemoglobin 152
Allosteric effectors of hemoglobin: past, present and future. 152
More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function 152
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes 151
ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus 151
Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7 150
High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model 149
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. 146
Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides 144
Mycobacterial and Human Nitrobindins: Structure and Function 144
Unusually fast bis-histidyl coordination in a plant hemoglobin 142
Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana 141
Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes. 140
Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives 139
PEGylation Promotes Hemoglobin Tetramer Dissociation 135
Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7 135
STRUCTURES OF GABA AMINOTRANSFERASE, A PYRIDOXAL 5'-PHOSPHATE AND [2FE-2S] CLUSTER CONTAINING ENZYME, COMPLEXED WITH THE ANTIEPILEPSY DRUG VIGABATRIN AND WITH GAMMA-ETHYNYLGABA 134
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions 134
Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form 131
New Insights into the Enhancement of Adventitious Root Formation Using N,N′-Bis(2,3-methylenedioxyphenyl)urea 130
Protein encapsulation, conformations, and nanobiotools 129
Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state 129
Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme 128
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule 128
Structural Plasticity and Functional Implications of Internal Cavities in Distal Mutants of Type 1 Non-Symbiotic Hemoglobin AHb1 from Arabidopsis thaliana 128
Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria 127
The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties 126
Oxygen Binding by a(Fe2+)2b(Ni2+)2 Hemoglobin Crystals 125
Protein carbonylation detection methods: A comparison 125
Functional and spectroscopic characterization of half liganded Fe-Zn hybrid hemoglobin: evidence for conformational plasticity within the t state 124
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis. 124
Oxygen Delivery by Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders 124
Heterogeneous Kinetics of the Carbon Monoxide Association and Dissociation Reaction to Nitrophorin 4 and 7 Coincide with Structural Heterogeneity of the Gate-Loop 124
Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization 124
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death 122
Recombinant Alpha-1 Antitrypsin as Dry Powder for Pulmonary Administration: A Formulative Proof of Concept 122
Zinc-substituted myoglobin is a naturally occurring photoantimicrobial agent with potential applications in food decontamination 122
The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase 120
Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro 117
Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration 117
The human phosphorylated pathway: a multienzyme metabolic assembly for l-serine biosynthesis 116
Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport. 116
Mutational effects at the subunit interfaces of human hemoglobin: evidence for a unique sensitivity of the T quaternary state to changes in the hinge region of the alpha1-beta2 interface 115
X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: A multidisciplinary characterization of catechol 1,2 dioxygenase 115
Biochemistry of hemoglobin 114
Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin. 114
Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases 113
Engineered chimeras reveal the structural basis of hexacoordination in globins: A case study of neuroglobin and myoglobin 113
Pegylation promotes hemoglobin tetramer dissociation 113
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 112
Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers 111
Ligand binding to human serine racemase: a spectroscopic and functional study 111
Immobilization of proteins in Ormosil gels: Functional properties and applications 110
Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins 109
Ligand migration through the internal hydrophobic cavities in human neuroglobin 108
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 108
Structural and Functional Characterization of the Globin-Coupled Sensors of Azotobacter vinelandii and Bordetella pertussis 108
Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins 107
Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models 107
Totale 15.052
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Categoria #
all - tutte 67.705
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.705
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022589 0 17 9 48 36 32 59 67 29 53 44 195
2022/20232.509 230 231 185 199 242 296 32 152 743 40 119 40
2023/20241.086 62 75 40 61 89 289 72 98 34 65 66 135
2024/20253.570 103 159 257 203 398 475 260 198 356 314 283 564
2025/20267.538 774 702 980 663 973 344 870 230 780 571 424 227
2026/2027452 172 280 0 0 0 0 0 0 0 0 0 0
Totale 18.952