IRIS
BRUNO, Stefano
 Distribuzione geografica
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Continente #
NA - Nord America 5.525
AS - Asia 4.340
EU - Europa 3.940
SA - Sud America 732
AF - Africa 248
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 14.793
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Nazione #
US - Stati Uniti d'America 5.384
SG - Singapore 1.782
CN - Cina 1.398
IT - Italia 794
IE - Irlanda 599
BR - Brasile 588
SE - Svezia 561
FI - Finlandia 543
DE - Germania 452
HK - Hong Kong 391
VN - Vietnam 253
UA - Ucraina 233
NL - Olanda 174
ZA - Sudafrica 161
TR - Turchia 158
GB - Regno Unito 122
AT - Austria 114
RU - Federazione Russa 91
CA - Canada 85
IN - India 85
AR - Argentina 66
FR - Francia 62
BD - Bangladesh 39
JP - Giappone 39
KR - Corea 37
MX - Messico 37
ID - Indonesia 35
CI - Costa d'Avorio 32
PL - Polonia 31
CZ - Repubblica Ceca 27
IQ - Iraq 26
EC - Ecuador 25
ES - Italia 23
BE - Belgio 22
RO - Romania 20
PK - Pakistan 17
LT - Lituania 16
CO - Colombia 12
EG - Egitto 12
MA - Marocco 10
UZ - Uzbekistan 10
VE - Venezuela 10
CH - Svizzera 9
CL - Cile 9
PY - Paraguay 9
AE - Emirati Arabi Uniti 8
KE - Kenya 8
PT - Portogallo 8
TN - Tunisia 8
IL - Israele 7
JO - Giordania 7
NP - Nepal 7
BY - Bielorussia 6
HN - Honduras 6
LU - Lussemburgo 6
CR - Costa Rica 5
HR - Croazia 5
LB - Libano 5
PE - Perù 5
UY - Uruguay 5
SA - Arabia Saudita 4
AZ - Azerbaigian 3
BG - Bulgaria 3
DZ - Algeria 3
ET - Etiopia 3
GE - Georgia 3
IR - Iran 3
KG - Kirghizistan 3
KZ - Kazakistan 3
MY - Malesia 3
NZ - Nuova Zelanda 3
RS - Serbia 3
SN - Senegal 3
TW - Taiwan 3
AL - Albania 2
AU - Australia 2
DK - Danimarca 2
EE - Estonia 2
EU - Europa 2
GA - Gabon 2
JM - Giamaica 2
MD - Moldavia 2
PA - Panama 2
PH - Filippine 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
AO - Angola 1
BF - Burkina Faso 1
BO - Bolivia 1
CG - Congo 1
DM - Dominica 1
DO - Repubblica Dominicana 1
GR - Grecia 1
GY - Guiana 1
HU - Ungheria 1
IS - Islanda 1
KH - Cambogia 1
KW - Kuwait 1
LK - Sri Lanka 1
Totale 14.781
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Città #
Singapore 869
Ashburn 719
Chandler 609
Dublin 595
Santa Clara 518
Dallas 426
Hong Kong 391
Beijing 338
Parma 294
Jacksonville 275
Dearborn 255
Ann Arbor 219
Munich 200
Boardman 178
New York 159
Nanjing 156
Johannesburg 147
Izmir 122
Princeton 115
Los Angeles 114
Hefei 103
Shanghai 99
Helsinki 97
Vienna 95
Ho Chi Minh City 87
Wilmington 70
San Mateo 65
Bremen 63
Columbus 57
Hanoi 56
Shenyang 56
Moscow 52
São Paulo 50
Toronto 48
Buffalo 47
Chicago 45
The Dalles 44
Milan 43
Guangzhou 41
Nanchang 39
Jinan 38
Piacenza 37
Kunming 36
Tokyo 36
Seoul 35
Hebei 33
Abidjan 32
Des Moines 32
Turku 30
Bangalore 27
London 27
Tianjin 27
Changsha 24
Council Bluffs 24
Jakarta 24
Marseille 24
Warsaw 24
Seattle 23
Bologna 22
Houston 20
Jiaxing 20
Woodbridge 20
Brussels 17
Haiphong 17
Brescia 16
Brno 16
Brooklyn 16
Modena 16
Nuremberg 16
Rio de Janeiro 16
Belo Horizonte 15
Falls Church 15
Orem 15
Haikou 14
Hangzhou 14
Montreal 14
Stockholm 14
Denver 13
Norwalk 13
Baghdad 12
Boston 12
Fidenza 12
Fremont 12
Phoenix 12
San Francisco 12
Ankara 11
Frankfurt am Main 11
Grafing 11
Mumbai 11
Rome 11
Atlanta 10
Mexico City 10
Poplar 10
Taiyuan 10
Tashkent 10
Brasília 9
Chennai 9
Fairfield 9
Kocaeli 9
Lanzhou 9
Totale 9.050
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Nome #
Targeting the Eph/ephrin system as anti-inflammatory strategy in IBD 228
Ligand migration in non symbiotic hemoglobin AHb1 from Arabidopsis thaliana 222
Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin 202
A phosphoserine phosphatase variant present in the brain of Alzheimer's disease patients favors nuclear mistargeting 180
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP 180
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase 175
Functional Characterization of Heme Proteins Encapsulated in Wet Nanoporous Silica Gels 174
High and low oxygen affinity conformations of T state hemoglobin 166
From hemoglobin allostery to hemoglobin-based oxygen carriers 166
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme 164
Augmentation therapy with alpha 1-antitrypsin: present and future of production, formulation, and delivery 161
Mycobacterial and human ferrous nitrobindins: Spectroscopic and reactivity properties 156
Nebulizers effectiveness on pulmonary delivery of alpha-1 antitrypsin 152
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels 150
A Photoactive Supramolecular Complex Targeting PD-L1 Reveals a Weak Correlation between Photoactivation Efficiency and Receptor Expression Levels in Non-Small-Cell Lung Cancer Tumor Models 147
The Energy Landscape of Human Serine Racemase 147
CO rebinding kinetics and molecular dynamics simulations highlight dynamic regulation of internal cavities in human cytoglobin 146
Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus 143
CO rebinding kinetics to high and low affinity T state hemoglobin encapsulated in silica gels 142
Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes 140
Biochemical platform for the identification of adverse effects triggered by free hemoglobin in guinea pigs 140
Biocatalysis in a confined environment. Lessons from enzymes immobilized in wet, nanoporous silica gels 140
Structural and functional properties of Antarctic fish cytoglobins-1: cold-reactivity in multi-ligand reactions 140
Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana 139
Characterization of ligand migration mechanisms inside haemoglobins from the analysis of geminate rebinding kinetics 139
Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor 136
Correlation of protein functional properties in the crystal and in solution: the case study of T state hemoglobin 136
Enhanced geminate ligand rebinding upon photo-dissociation of silica gels-embedded myoglobin-CO 136
Time-resolved methods in biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis 136
A photosensitizing fusion protein with targeting capabilities 135
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes 130
Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7 129
Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants 128
Human serine racemase is nitrosylated at multiple sites 128
L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase 127
Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95 126
Genetically Encoded Biosensors for the Fluorescence Detection of O2 and Reactive O2 Species 125
Kinetic and dynamical properties of truncated hemoglobins of the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 125
More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function 125
ATP binding to human serine racemase is cooperative and modulated by glycine 125
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions 124
Allosteric effectors of hemoglobin: past, present and future. 123
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. 123
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 122
Nitric Oxide Sensing by a Blue Fluorescent Protein 119
Cold-Adaptation Signatures in the Ligand Rebinding Kinetics to the Truncated Hemoglobin of the Antarctic Bacterium Pseudoalteromonas haloplanktis TAC125 119
Mass spectrometry-based proteomic strategy for ecchymotic skin examination in forensic pathology 118
The Reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is Controlled by the Distal HisE7 and Internal Hydrophobic Cavities 118
Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes. 118
ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus 118
Unusually fast bis-histidyl coordination in a plant hemoglobin 118
Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana 117
High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model 115
Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives 115
PEGylation Promotes Hemoglobin Tetramer Dissociation 112
Functional and spectroscopic characterization of half liganded Fe-Zn hybrid hemoglobin: evidence for conformational plasticity within the t state 110
Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7 109
Protein carbonylation detection methods: A comparison 109
Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme 108
Mycobacterial and Human Nitrobindins: Structure and Function 108
Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form 108
The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase 107
Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state 107
Oxygen Delivery by Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders 107
Oxygen Binding by a(Fe2+)2b(Ni2+)2 Hemoglobin Crystals 105
Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides 104
Zinc-substituted myoglobin is a naturally occurring photoantimicrobial agent with potential applications in food decontamination 104
Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport. 103
Protein encapsulation, conformations, and nanobiotools 103
Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro 103
Engineered chimeras reveal the structural basis of hexacoordination in globins: A case study of neuroglobin and myoglobin 103
Mutational effects at the subunit interfaces of human hemoglobin: evidence for a unique sensitivity of the T quaternary state to changes in the hinge region of the alpha1-beta2 interface 102
Recombinant Alpha-1 Antitrypsin as Dry Powder for Pulmonary Administration: A Formulative Proof of Concept 101
The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties 101
STRUCTURES OF GABA AMINOTRANSFERASE, A PYRIDOXAL 5'-PHOSPHATE AND [2FE-2S] CLUSTER CONTAINING ENZYME, COMPLEXED WITH THE ANTIEPILEPSY DRUG VIGABATRIN AND WITH GAMMA-ETHYNYLGABA 100
Structural Plasticity and Functional Implications of Internal Cavities in Distal Mutants of Type 1 Non-Symbiotic Hemoglobin AHb1 from Arabidopsis thaliana 99
Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria 99
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule 98
X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: A multidisciplinary characterization of catechol 1,2 dioxygenase 98
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis. 97
Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases 97
Ligand binding to human serine racemase: a spectroscopic and functional study 96
Pegylation promotes hemoglobin tetramer dissociation 96
The human phosphorylated pathway: a multienzyme metabolic assembly for l-serine biosynthesis 95
Immobilization of proteins in Ormosil gels: Functional properties and applications 95
Following Ligand Migration Pathways from Picoseconds to Milliseconds in Type IITruncated Hemoglobin from Thermobifida fusca 95
Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration 95
Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers 93
Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins 93
Heterogeneous Kinetics of the Carbon Monoxide Association and Dissociation Reaction to Nitrophorin 4 and 7 Coincide with Structural Heterogeneity of the Gate-Loop 93
Ligand migration through the internal hydrophobic cavities in human neuroglobin 92
Biochemistry of hemoglobin 92
Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin. 92
Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins 92
Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models 90
Trapping hemoglobin in rigid matrices: fine tuning of oxygen binding properties by modulation of encapsulation protocols 90
ENZIMI CATECOLO 1,2 DIOSSIGENASI INCAPSULATI IN GEL DI SILICE E/O DI ORMOSILI, PROCEDIMENTO DI INCAPSULAMENTO DIDETTI ENZIMI IN GEL DI SILICE E/O DI ORMOSILI, ED USO DI DETTI ENZIMI INCAPSULATI PER IL BIORISANAMENTO DI MATERIALICONTAMINATI CON CATECOLI E LORO DERIVATI 89
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 88
Oxygen and Nitric Oxide Rebinding Kinetics in Nonsymbiotic Hemoglobin AHb1 from Arabidopsis thaliana 88
Human serine racemase, a key enzyme in neurophysiology and neuropathologies 87
Totale 12.206
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Categoria #
all - tutte 55.287
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.287
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021471 0 0 0 0 0 26 81 26 190 28 79 41
2021/2022609 20 17 9 48 36 32 59 67 29 53 44 195
2022/20232.509 230 231 185 199 242 296 32 152 743 40 119 40
2023/20241.086 62 75 40 61 89 289 72 98 34 65 66 135
2024/20253.570 103 159 257 203 398 475 260 198 356 314 283 564
2025/20264.164 774 702 980 663 973 72 0 0 0 0 0 0
Totale 15.126