BRUNO, Stefano
 Distribuzione geografica
Continente #
NA - Nord America 4.323
EU - Europa 3.761
AS - Asia 2.475
SA - Sud America 408
AF - Africa 66
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 2
Totale 11.040
Nazione #
US - Stati Uniti d'America 4.231
CN - Cina 966
SG - Singapore 793
IT - Italia 763
IE - Irlanda 598
SE - Svezia 547
FI - Finlandia 543
DE - Germania 446
HK - Hong Kong 371
BR - Brasile 358
UA - Ucraina 224
NL - Olanda 172
TR - Turchia 147
AT - Austria 112
GB - Regno Unito 88
RU - Federazione Russa 72
CA - Canada 63
IN - India 61
FR - Francia 53
CI - Costa d'Avorio 32
CZ - Repubblica Ceca 27
BE - Belgio 22
AR - Argentina 21
ID - Indonesia 20
VN - Vietnam 20
MX - Messico 19
RO - Romania 18
BD - Bangladesh 15
PL - Polonia 13
ES - Italia 10
IQ - Iraq 9
LT - Lituania 9
PK - Pakistan 9
EC - Ecuador 8
EG - Egitto 8
ZA - Sudafrica 8
PT - Portogallo 7
UZ - Uzbekistan 7
IL - Israele 6
JP - Giappone 6
KR - Corea 6
LU - Lussemburgo 6
VE - Venezuela 6
AE - Emirati Arabi Uniti 5
KE - Kenya 5
MA - Marocco 5
CH - Svizzera 4
CO - Colombia 4
HR - Croazia 4
SA - Arabia Saudita 4
TN - Tunisia 4
AZ - Azerbaigian 3
BG - Bulgaria 3
BY - Bielorussia 3
GE - Georgia 3
IR - Iran 3
JO - Giordania 3
KG - Kirghizistan 3
LB - Libano 3
NP - Nepal 3
NZ - Nuova Zelanda 3
PE - Perù 3
PY - Paraguay 3
RS - Serbia 3
TW - Taiwan 3
AU - Australia 2
CL - Cile 2
DK - Danimarca 2
EE - Estonia 2
EU - Europa 2
HN - Honduras 2
JM - Giamaica 2
KZ - Kazakistan 2
MD - Moldavia 2
PA - Panama 2
SN - Senegal 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
UY - Uruguay 2
AL - Albania 1
AO - Angola 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
GR - Grecia 1
GY - Guiana 1
HU - Ungheria 1
IS - Islanda 1
KW - Kuwait 1
MC - Monaco 1
MK - Macedonia 1
NG - Nigeria 1
NO - Norvegia 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 11.040
Città #
Chandler 609
Dublin 594
Singapore 496
Santa Clara 494
Ashburn 436
Hong Kong 371
Parma 281
Jacksonville 273
Dearborn 255
Ann Arbor 219
Munich 198
Boardman 175
Beijing 173
Nanjing 154
New York 128
Izmir 122
Princeton 115
Helsinki 97
Shanghai 95
Vienna 95
Wilmington 70
San Mateo 65
Bremen 63
Hefei 58
Columbus 57
Shenyang 55
Moscow 50
Los Angeles 49
Toronto 43
Milan 42
Chicago 39
Nanchang 39
Piacenza 37
Kunming 36
Jinan 35
The Dalles 35
Guangzhou 34
Hebei 33
Abidjan 32
Des Moines 32
Turku 30
Bangalore 27
Council Bluffs 24
Marseille 24
Tianjin 22
Changsha 21
Jiaxing 20
Seattle 20
Woodbridge 20
Bologna 19
London 19
São Paulo 18
Brussels 17
Dallas 17
Brescia 16
Brno 16
Houston 16
Jakarta 16
Modena 16
Falls Church 15
Nuremberg 15
Haikou 14
Norwalk 13
Fidenza 12
Fremont 12
Hangzhou 12
Grafing 11
Rome 11
Belo Horizonte 10
Frankfurt am Main 10
Rio de Janeiro 10
Taiyuan 10
Fairfield 9
Kocaeli 9
Zhengzhou 9
Edinburgh 8
Hanoi 8
Pune 8
Amsterdam 7
Brooklyn 7
Istanbul 7
Lanzhou 7
Leawood 7
Ottawa 7
Rockville 7
Tashkent 7
Warsaw 7
Baghdad 6
Brasília 6
Fiorano Modenese 6
Fuzhou 6
La Plata 6
Ningbo 6
Porto Alegre 6
Río Cuarto 6
Southend 6
Taizhou 6
Torino 6
Viano 6
Asti 5
Totale 7.008
Nome #
Ligand migration in non symbiotic hemoglobin AHb1 from Arabidopsis thaliana 209
Targeting the Eph/ephrin system as anti-inflammatory strategy in IBD 185
Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin 143
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase 138
Functional Characterization of Heme Proteins Encapsulated in Wet Nanoporous Silica Gels 137
Mycobacterial and human ferrous nitrobindins: Spectroscopic and reactivity properties 136
From hemoglobin allostery to hemoglobin-based oxygen carriers 136
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP 135
Augmentation therapy with alpha 1-antitrypsin: present and future of production, formulation, and delivery 131
The Energy Landscape of Human Serine Racemase 121
High and low oxygen affinity conformations of T state hemoglobin 120
Nebulizers effectiveness on pulmonary delivery of alpha-1 antitrypsin 115
Correlation of protein functional properties in the crystal and in solution: the case study of T state hemoglobin 115
Enhanced geminate ligand rebinding upon photo-dissociation of silica gels-embedded myoglobin-CO 115
Structural and functional properties of Antarctic fish cytoglobins-1: cold-reactivity in multi-ligand reactions 113
CO rebinding kinetics to high and low affinity T state hemoglobin encapsulated in silica gels 112
Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes 112
Characterization of ligand migration mechanisms inside haemoglobins from the analysis of geminate rebinding kinetics 112
Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana 111
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels 111
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme 111
Time-resolved methods in biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis 109
Biochemical platform for the identification of adverse effects triggered by free hemoglobin in guinea pigs 107
Biocatalysis in a confined environment. Lessons from enzymes immobilized in wet, nanoporous silica gels 104
Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7 104
CO rebinding kinetics and molecular dynamics simulations highlight dynamic regulation of internal cavities in human cytoglobin 104
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions 102
A photosensitizing fusion protein with targeting capabilities 101
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes 100
More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function 100
Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme 99
Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes. 99
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 99
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. 99
ATP binding to human serine racemase is cooperative and modulated by glycine 99
Unusually fast bis-histidyl coordination in a plant hemoglobin 97
Nitric Oxide Sensing by a Blue Fluorescent Protein 95
A Photoactive Supramolecular Complex Targeting PD-L1 Reveals a Weak Correlation between Photoactivation Efficiency and Receptor Expression Levels in Non-Small-Cell Lung Cancer Tumor Models 95
Allosteric effectors of hemoglobin: past, present and future. 94
Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives 94
The Reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is Controlled by the Distal HisE7 and Internal Hydrophobic Cavities 93
Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana 93
Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus 93
PEGylation Promotes Hemoglobin Tetramer Dissociation 92
Human serine racemase is nitrosylated at multiple sites 92
Functional and spectroscopic characterization of half liganded Fe-Zn hybrid hemoglobin: evidence for conformational plasticity within the t state 91
Mycobacterial and Human Nitrobindins: Structure and Function 91
Oxygen Binding by a(Fe2+)2b(Ni2+)2 Hemoglobin Crystals 90
Protein encapsulation, conformations, and nanobiotools 90
Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state 89
Genetically Encoded Biosensors for the Fluorescence Detection of O2 and Reactive O2 Species 88
High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model 88
Oxygen Delivery by Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders 87
Protein carbonylation detection methods: A comparison 86
Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration 86
Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7 85
Mutational effects at the subunit interfaces of human hemoglobin: evidence for a unique sensitivity of the T quaternary state to changes in the hinge region of the alpha1-beta2 interface 84
ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus 84
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule 84
Immobilization of proteins in Ormosil gels: Functional properties and applications 83
The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties 83
STRUCTURES OF GABA AMINOTRANSFERASE, A PYRIDOXAL 5'-PHOSPHATE AND [2FE-2S] CLUSTER CONTAINING ENZYME, COMPLEXED WITH THE ANTIEPILEPSY DRUG VIGABATRIN AND WITH GAMMA-ETHYNYLGABA 82
Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides 82
Engineered chimeras reveal the structural basis of hexacoordination in globins: A case study of neuroglobin and myoglobin 82
Pegylation promotes hemoglobin tetramer dissociation 82
Cold-Adaptation Signatures in the Ligand Rebinding Kinetics to the Truncated Hemoglobin of the Antarctic Bacterium Pseudoalteromonas haloplanktis TAC125 81
Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form 81
L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase 80
Mass spectrometry-based proteomic strategy for ecchymotic skin examination in forensic pathology 80
Ligand binding to human serine racemase: a spectroscopic and functional study 80
Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models 79
Structural Plasticity and Functional Implications of Internal Cavities in Distal Mutants of Type 1 Non-Symbiotic Hemoglobin AHb1 from Arabidopsis thaliana 79
Zinc-substituted myoglobin is a naturally occurring photoantimicrobial agent with potential applications in food decontamination 79
The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase 77
Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants 77
Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport. 77
Ligand migration through the internal hydrophobic cavities in human neuroglobin 76
Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers 76
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis. 76
Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins 76
Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria 76
X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: A multidisciplinary characterization of catechol 1,2 dioxygenase 75
Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor 74
Trapping hemoglobin in rigid matrices: fine tuning of oxygen binding properties by modulation of encapsulation protocols 74
Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin. 74
Ligand migration and hexacoordination in type 1 non symbiotic rice hemoglobin 73
Following Ligand Migration Pathways from Picoseconds to Milliseconds in Type IITruncated Hemoglobin from Thermobifida fusca 73
Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro 73
Heterogeneous Kinetics of the Carbon Monoxide Association and Dissociation Reaction to Nitrophorin 4 and 7 Coincide with Structural Heterogeneity of the Gate-Loop 73
Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins 72
Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases 69
Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95 68
The human phosphorylated pathway: a multienzyme metabolic assembly for l-serine biosynthesis 67
Functional properties of human cystathionine beta-synthase crystals. 67
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 67
Oxygen and Nitric Oxide Rebinding Kinetics in Nonsymbiotic Hemoglobin AHb1 from Arabidopsis thaliana 67
Kinetic and dynamical properties of truncated hemoglobins of the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 66
Oxygen binding by single red blood celles from the red-eared turtle Trachemys scripta 66
Recombinant Alpha-1 Antitrypsin as Dry Powder for Pulmonary Administration: A Formulative Proof of Concept 65
Biochemistry of hemoglobin 65
Totale 9.377
Categoria #
all - tutte 45.207
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.207


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021741 12 73 47 16 122 26 81 26 190 28 79 41
2021/2022609 20 17 9 48 36 32 59 67 29 53 44 195
2022/20232.509 230 231 185 199 242 296 32 152 743 40 119 40
2023/20241.086 62 75 40 61 89 289 72 98 34 65 66 135
2024/20253.570 103 159 257 203 398 475 260 198 356 314 283 564
2025/2026406 406 0 0 0 0 0 0 0 0 0 0 0
Totale 11.368