IRIS
BRUNO, Stefano
 Distribuzione geografica
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Continente #
NA - Nord America 6.485
AS - Asia 5.572
EU - Europa 4.198
SA - Sud America 831
AF - Africa 309
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 2
Totale 17.406
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Nazione #
US - Stati Uniti d'America 6.323
SG - Singapore 2.105
CN - Cina 1.496
IT - Italia 831
VN - Vietnam 807
BR - Brasile 645
IE - Irlanda 602
SE - Svezia 564
FI - Finlandia 545
DE - Germania 474
HK - Hong Kong 439
UA - Ucraina 241
FR - Francia 197
ZA - Sudafrica 190
NL - Olanda 178
TR - Turchia 170
GB - Regno Unito 133
AT - Austria 114
IN - India 109
RU - Federazione Russa 98
CA - Canada 93
AR - Argentina 75
BD - Bangladesh 64
JP - Giappone 51
IQ - Iraq 45
KR - Corea 45
MX - Messico 44
ID - Indonesia 43
CI - Costa d'Avorio 34
PL - Polonia 34
PK - Pakistan 33
EC - Ecuador 31
ES - Italia 31
CZ - Repubblica Ceca 28
BE - Belgio 22
PH - Filippine 22
CO - Colombia 21
RO - Romania 20
TH - Thailandia 18
LT - Lituania 17
EG - Egitto 16
TN - Tunisia 15
UZ - Uzbekistan 15
VE - Venezuela 15
JO - Giordania 14
MA - Marocco 14
CL - Cile 13
KE - Kenya 12
MY - Malesia 12
TW - Taiwan 12
PT - Portogallo 11
CH - Svizzera 10
PY - Paraguay 10
SA - Arabia Saudita 10
AE - Emirati Arabi Uniti 9
IL - Israele 9
NP - Nepal 9
UY - Uruguay 8
CR - Costa Rica 7
LB - Libano 7
BY - Bielorussia 6
DZ - Algeria 6
ET - Etiopia 6
HN - Honduras 6
LU - Lussemburgo 6
PE - Perù 6
AU - Australia 5
BO - Bolivia 5
HR - Croazia 5
SN - Senegal 5
BG - Bulgaria 4
IR - Iran 4
KZ - Kazakistan 4
MD - Moldavia 4
AL - Albania 3
AZ - Azerbaigian 3
DK - Danimarca 3
GE - Georgia 3
JM - Giamaica 3
KG - Kirghizistan 3
NG - Nigeria 3
NZ - Nuova Zelanda 3
RS - Serbia 3
DO - Repubblica Dominicana 2
EE - Estonia 2
EU - Europa 2
GA - Gabon 2
GR - Grecia 2
PA - Panama 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
TT - Trinidad e Tobago 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
CG - Congo 1
DM - Dominica 1
Totale 17.385
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Città #
Singapore 1.062
Ashburn 837
Chandler 609
Dublin 598
San Jose 591
Santa Clara 524
Dallas 429
Hong Kong 422
Beijing 342
Parma 294
Jacksonville 275
Dearborn 255
Ho Chi Minh City 225
Ann Arbor 219
Munich 200
Hanoi 197
Boardman 192
Johannesburg 174
New York 164
Nanjing 156
Los Angeles 126
Izmir 122
Lauterbourg 122
Princeton 115
Hefei 103
Shanghai 101
Helsinki 99
Vienna 95
Wilmington 70
San Mateo 65
Bremen 63
Buffalo 62
Columbus 57
São Paulo 57
Shenyang 56
Milan 54
Moscow 53
Toronto 52
Chicago 50
The Dalles 50
Tokyo 42
Council Bluffs 41
Guangzhou 41
Nanchang 39
Jinan 38
Da Nang 37
Piacenza 37
Kunming 36
Seoul 35
Abidjan 34
Des Moines 33
Hebei 33
Turku 30
Tianjin 29
Haiphong 28
London 28
Bangalore 27
Bologna 27
Warsaw 27
Jakarta 26
Marseille 25
Changsha 24
Orem 24
Frankfurt am Main 23
Seattle 23
Baghdad 20
Houston 20
Jiaxing 20
Woodbridge 20
Nuremberg 19
Brussels 17
Rio de Janeiro 17
Stockholm 17
Belo Horizonte 16
Brescia 16
Brno 16
Brooklyn 16
Modena 16
Atlanta 15
Falls Church 15
Tashkent 15
Biên Hòa 14
Haikou 14
Hangzhou 14
Montreal 14
Rome 14
Denver 13
Mumbai 13
Norwalk 13
Amman 12
Boston 12
Fidenza 12
Fremont 12
Mexico City 12
Phoenix 12
San Francisco 12
Ankara 11
Can Tho 11
Grafing 11
Istanbul 11
Totale 10.636
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Nome #
Targeting the Eph/ephrin system as anti-inflammatory strategy in IBD 250
Ligand migration in non symbiotic hemoglobin AHb1 from Arabidopsis thaliana 233
Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin 232
A phosphoserine phosphatase variant present in the brain of Alzheimer's disease patients favors nuclear mistargeting 217
High and low oxygen affinity conformations of T state hemoglobin 214
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP 211
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase 197
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme 191
Functional Characterization of Heme Proteins Encapsulated in Wet Nanoporous Silica Gels 190
Augmentation therapy with alpha 1-antitrypsin: present and future of production, formulation, and delivery 188
From hemoglobin allostery to hemoglobin-based oxygen carriers 183
A Photoactive Supramolecular Complex Targeting PD-L1 Reveals a Weak Correlation between Photoactivation Efficiency and Receptor Expression Levels in Non-Small-Cell Lung Cancer Tumor Models 181
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels 175
Biocatalysis in a confined environment. Lessons from enzymes immobilized in wet, nanoporous silica gels 174
Mycobacterial and human ferrous nitrobindins: Spectroscopic and reactivity properties 172
Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor 170
Nebulizers effectiveness on pulmonary delivery of alpha-1 antitrypsin 170
CO rebinding kinetics and molecular dynamics simulations highlight dynamic regulation of internal cavities in human cytoglobin 170
The Energy Landscape of Human Serine Racemase 167
A photosensitizing fusion protein with targeting capabilities 166
Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants 165
L-serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase 164
Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana 163
Characterization of ligand migration mechanisms inside haemoglobins from the analysis of geminate rebinding kinetics 162
Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus 162
Structural and functional properties of Antarctic fish cytoglobins-1: cold-reactivity in multi-ligand reactions 162
Kinetic and dynamical properties of truncated hemoglobins of the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 160
CO rebinding kinetics to high and low affinity T state hemoglobin encapsulated in silica gels 160
Biochemical platform for the identification of adverse effects triggered by free hemoglobin in guinea pigs 159
Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95 156
Enhanced geminate ligand rebinding upon photo-dissociation of silica gels-embedded myoglobin-CO 156
ATP binding to human serine racemase is cooperative and modulated by glycine 156
Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes 155
Time-resolved methods in biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis 154
Genetically Encoded Biosensors for the Fluorescence Detection of O2 and Reactive O2 Species 152
Correlation of protein functional properties in the crystal and in solution: the case study of T state hemoglobin 150
Allosteric effectors of hemoglobin: past, present and future. 148
Human serine racemase is nitrosylated at multiple sites 148
Nitric Oxide Sensing by a Blue Fluorescent Protein 146
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes 146
More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function 146
Mass spectrometry-based proteomic strategy for ecchymotic skin examination in forensic pathology 144
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. 143
Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7 142
Cold-Adaptation Signatures in the Ligand Rebinding Kinetics to the Truncated Hemoglobin of the Antarctic Bacterium Pseudoalteromonas haloplanktis TAC125 141
ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus 138
Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana 138
The Reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is Controlled by the Distal HisE7 and Internal Hydrophobic Cavities 136
Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes. 135
High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model 134
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 133
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions 133
Unusually fast bis-histidyl coordination in a plant hemoglobin 131
PEGylation Promotes Hemoglobin Tetramer Dissociation 128
Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form 127
Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7 126
Mycobacterial and Human Nitrobindins: Structure and Function 126
Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives 126
Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state 125
Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides 124
Oxygen Binding by a(Fe2+)2b(Ni2+)2 Hemoglobin Crystals 123
Protein encapsulation, conformations, and nanobiotools 123
Protein carbonylation detection methods: A comparison 123
Functional and spectroscopic characterization of half liganded Fe-Zn hybrid hemoglobin: evidence for conformational plasticity within the t state 122
Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme 121
Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria 120
The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase 119
Oxygen Delivery by Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders 119
Structural Plasticity and Functional Implications of Internal Cavities in Distal Mutants of Type 1 Non-Symbiotic Hemoglobin AHb1 from Arabidopsis thaliana 119
Recombinant Alpha-1 Antitrypsin as Dry Powder for Pulmonary Administration: A Formulative Proof of Concept 117
The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties 117
Zinc-substituted myoglobin is a naturally occurring photoantimicrobial agent with potential applications in food decontamination 117
Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro 116
STRUCTURES OF GABA AMINOTRANSFERASE, A PYRIDOXAL 5'-PHOSPHATE AND [2FE-2S] CLUSTER CONTAINING ENZYME, COMPLEXED WITH THE ANTIEPILEPSY DRUG VIGABATRIN AND WITH GAMMA-ETHYNYLGABA 114
Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport. 114
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule 114
The human phosphorylated pathway: a multienzyme metabolic assembly for l-serine biosynthesis 113
X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: A multidisciplinary characterization of catechol 1,2 dioxygenase 113
Mutational effects at the subunit interfaces of human hemoglobin: evidence for a unique sensitivity of the T quaternary state to changes in the hinge region of the alpha1-beta2 interface 112
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis. 112
Biochemistry of hemoglobin 112
Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases 111
Engineered chimeras reveal the structural basis of hexacoordination in globins: A case study of neuroglobin and myoglobin 111
New Insights into the Enhancement of Adventitious Root Formation Using N,N′-Bis(2,3-methylenedioxyphenyl)urea 110
Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration 110
Pegylation promotes hemoglobin tetramer dissociation 110
Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin. 110
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death 109
Heterogeneous Kinetics of the Carbon Monoxide Association and Dissociation Reaction to Nitrophorin 4 and 7 Coincide with Structural Heterogeneity of the Gate-Loop 109
Ligand binding to human serine racemase: a spectroscopic and functional study 108
Immobilization of proteins in Ormosil gels: Functional properties and applications 108
Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers 107
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells 106
Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins 106
Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins 106
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 105
Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization 105
Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models 103
Trapping hemoglobin in rigid matrices: fine tuning of oxygen binding properties by modulation of encapsulation protocols 103
Structural and Functional Characterization of the Globin-Coupled Sensors of Azotobacter vinelandii and Bordetella pertussis 103
Totale 14.151
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Categoria #
all - tutte 60.579
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.579
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021148 0 0 0 0 0 0 0 0 0 28 79 41
2021/2022609 20 17 9 48 36 32 59 67 29 53 44 195
2022/20232.509 230 231 185 199 242 296 32 152 743 40 119 40
2023/20241.086 62 75 40 61 89 289 72 98 34 65 66 135
2024/20253.570 103 159 257 203 398 475 260 198 356 314 283 564
2025/20266.779 774 702 980 663 973 344 870 230 780 463 0 0
Totale 17.741