BRUNO, Stefano
 Distribuzione geografica
Continente #
NA - Nord America 2.975
EU - Europa 2.840
AS - Asia 1.054
SA - Sud America 12
OC - Oceania 3
AF - Africa 2
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.888
Nazione #
US - Stati Uniti d'America 2.930
CN - Cina 800
IE - Irlanda 592
IT - Italia 548
SE - Svezia 541
FI - Finlandia 458
UA - Ucraina 221
DE - Germania 218
TR - Turchia 133
AT - Austria 89
GB - Regno Unito 56
IN - India 49
SG - Singapore 48
CA - Canada 41
BE - Belgio 19
FR - Francia 18
RO - Romania 15
NL - Olanda 14
AR - Argentina 11
CZ - Repubblica Ceca 8
PL - Polonia 8
LU - Lussemburgo 6
MX - Messico 4
VN - Vietnam 4
BY - Bielorussia 3
ES - Italia 3
HR - Croazia 3
IL - Israele 3
IR - Iran 3
PK - Pakistan 3
RU - Federazione Russa 3
TW - Taiwan 3
CH - Svizzera 2
DK - Danimarca 2
EU - Europa 2
JP - Giappone 2
KR - Corea 2
LT - Lituania 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
RS - Serbia 2
TH - Thailandia 2
AU - Australia 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BR - Brasile 1
EE - Estonia 1
EG - Egitto 1
GR - Grecia 1
IS - Islanda 1
KZ - Kazakistan 1
MC - Monaco 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
ZA - Sudafrica 1
Totale 6.888
Città #
Chandler 604
Dublin 588
Jacksonville 273
Dearborn 255
Ashburn 221
Ann Arbor 219
Parma 198
Nanjing 154
Beijing 151
New York 122
Izmir 121
Princeton 115
Vienna 87
Wilmington 70
San Mateo 65
Bremen 62
Shanghai 59
Shenyang 55
Helsinki 45
Nanchang 39
Piacenza 37
Kunming 36
Jinan 35
Hebei 33
Des Moines 32
Toronto 32
Los Angeles 31
Boardman 30
Guangzhou 28
Bangalore 27
Hefei 23
Milan 23
Changsha 21
Tianjin 21
Jiaxing 20
Seattle 20
Woodbridge 20
Falls Church 15
Houston 15
Brussels 14
Haikou 14
Modena 14
Bologna 13
Norwalk 13
Fremont 12
Grafing 11
Hangzhou 11
Brescia 10
Rome 10
Taiyuan 10
Kocaeli 9
Zhengzhou 9
Edinburgh 8
Fairfield 8
Pune 8
Leawood 7
Rockville 7
Lanzhou 6
London 6
Ningbo 6
Río Cuarto 6
Southend 6
Torino 6
Viano 6
Asti 5
Auburn Hills 5
Bala-Cynwyd 5
Focsani 5
Heidelberg 5
La Plata 5
Luxembourg 5
Redwood City 5
Taizhou 5
Chicago 4
Dong Ket 4
Florence 4
Fuzhou 4
Krakow 4
Mansfield 4
Oranienburg 4
Reggio Emilia 4
Baotou 3
Boretto 3
Borås 3
Catania 3
Chengdu 3
Frankfurt am Main 3
Genoa 3
Louvain 3
Lyon 3
Madrid 3
Massa 3
Mestre 3
Miami 3
Multan 3
Mumbai 3
Ottawa 3
Palermo 3
Reggio Nell'emilia 3
Rieti 3
Totale 4.366
Nome #
Targeting the Eph/ephrin system as anti-inflammatory strategy in IBD 151
Biophysical characterisation of neuroglobin of the icefish, a natural knockout for hemoglobin and myoglobin. Comparison with human neuroglobin 105
Functional Characterization of Heme Proteins Encapsulated in Wet Nanoporous Silica Gels 103
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP 100
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase 97
The Energy Landscape of Human Serine Racemase 92
Enhanced geminate ligand rebinding upon photo-dissociation of silica gels-embedded myoglobin-CO 91
Time-resolved methods in biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis 89
Electrophoretic analysis of PEGylated hemoglobin-based blood substitutes 89
Augmentation therapy with alpha 1-antitrypsin: present and future of production, formulation, and delivery 85
Correlation of protein functional properties in the crystal and in solution: the case study of T state hemoglobin 84
Mycobacterial and human ferrous nitrobindins: Spectroscopic and reactivity properties 84
Characterization of ligand migration mechanisms inside haemoglobins from the analysis of geminate rebinding kinetics 83
From hemoglobin allostery to hemoglobin-based oxygen carriers 82
CO rebinding kinetics to high and low affinity T state hemoglobin encapsulated in silica gels 81
Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7 81
Structural basis for the oxidation of thiosulfate by a sulfur cycle enzyme 80
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes 80
Structural and functional properties of Antarctic fish cytoglobins-1: cold-reactivity in multi-ligand reactions 80
High and low oxygen affinity conformations of T state hemoglobin 79
CO rebinding kinetics and molecular dynamics simulations highlight dynamic regulation of internal cavities in human cytoglobin 77
Biochemical platform for the identification of adverse effects triggered by free hemoglobin in guinea pigs 76
More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function 75
Unusually fast bis-histidyl coordination in a plant hemoglobin 75
Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes. 74
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels 74
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions 74
The Reactivity with CO of AHb1 and AHb2 from Arabidopsis thaliana is Controlled by the Distal HisE7 and Internal Hydrophobic Cavities 73
Histidine E7 Dynamics Modulates Ligand Exchange between Distal Pocket and Solvent in AHb1 from Arabidopsis thaliana 73
Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana 72
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme 72
Functional and spectroscopic characterization of half liganded Fe-Zn hybrid hemoglobin: evidence for conformational plasticity within the t state 70
Mutational effects at the subunit interfaces of human hemoglobin: evidence for a unique sensitivity of the T quaternary state to changes in the hinge region of the alpha1-beta2 interface 68
PEGylation Promotes Hemoglobin Tetramer Dissociation 68
Protein encapsulation, conformations, and nanobiotools 68
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. 68
Oxygen Binding by a(Fe2+)2b(Ni2+)2 Hemoglobin Crystals 66
Mycobacterial and Human Nitrobindins: Structure and Function 66
Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state 66
Oxygen Delivery by Allosteric Effectors of Hemoglobin, Blood Substitutes, and Plasma Expanders 64
Structural Plasticity and Functional Implications of Internal Cavities in Distal Mutants of Type 1 Non-Symbiotic Hemoglobin AHb1 from Arabidopsis thaliana 61
Human serine racemase is allosterically modulated by NADH and reduced nicotinamide derivatives 61
A photosensitizing fusion protein with targeting capabilities 61
High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model 60
Human serine racemase is nitrosylated at multiple sites 60
Oxygen binding to Arabidopsis thaliana AHb2 nonsymbiotic hemoglobin: evidence for a role in oxygen transport. 59
Immobilization of proteins in Ormosil gels: Functional properties and applications 59
Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration 59
Pegylation promotes hemoglobin tetramer dissociation 59
Characterization of the Heme Pocket Structure and Ligand Binding Kinetics of Non-symbiotic Hemoglobins from the Model Legume Lotus japonicus 59
Ligand migration through the internal hydrophobic cavities in human neuroglobin 58
The Greenland shark Somniosus microcephalus—Hemoglobins and ligand-binding properties 58
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule 58
ATP binding to human serine racemase is cooperative and modulated by glycine 58
Nebulizers effectiveness on pulmonary delivery of alpha-1 antitrypsin 57
STRUCTURES OF GABA AMINOTRANSFERASE, A PYRIDOXAL 5'-PHOSPHATE AND [2FE-2S] CLUSTER CONTAINING ENZYME, COMPLEXED WITH THE ANTIEPILEPSY DRUG VIGABATRIN AND WITH GAMMA-ETHYNYLGABA 57
Biocatalysis in a confined environment. Lessons from enzymes immobilized in wet, nanoporous silica gels 57
Ligand binding to human serine racemase: a spectroscopic and functional study 57
Protein carbonylation detection methods: A comparison 57
X-ray crystallography, mass spectrometry and single crystal microspectrophotometry: A multidisciplinary characterization of catechol 1,2 dioxygenase 57
Discovery of covalent inhibitors of glyceraldehyde-3-phosphate dehydrogenase, a target for the treatment of malaria 56
Ligand reactivity and allosteric regulation of hemoglobin-based oxygen carriers 55
ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus 55
Functional characterisation of the haemoglobins of the migratory notothenioid fish Dissostichus eleginoides 55
Engineered chimeras reveal the structural basis of hexacoordination in globins: A case study of neuroglobin and myoglobin 55
Ligand migration and hexacoordination in type 1 non symbiotic rice hemoglobin 53
Allosteric effectors of hemoglobin: past, present and future. 53
Ligand-induced tertiary relaxations during the T-to-R quaternary transition in hemoglobin. 53
Ligand Uptake Modulation by Internal Water Molecules and Hydrophobic Cavities in Hemoglobins 53
Mass spectrometry-based proteomic strategy for ecchymotic skin examination in forensic pathology 52
Functional properties of human cystathionine beta-synthase crystals. 52
Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7 52
Ligand migration in non symbiotic hemoglobin AHb1 from Arabidopsis thaliana 52
Oxygen binding by single red blood celles from the red-eared turtle Trachemys scripta 51
Heterogeneous Kinetics of the Carbon Monoxide Association and Dissociation Reaction to Nitrophorin 4 and 7 Coincide with Structural Heterogeneity of the Gate-Loop 51
Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models 50
Trapping hemoglobin in rigid matrices: fine tuning of oxygen binding properties by modulation of encapsulation protocols 50
Following Ligand Migration Pathways from Picoseconds to Milliseconds in Type IITruncated Hemoglobin from Thermobifida fusca 50
Targeting Cystalysin, a Virulence Factor of Treponema denticola-Supported Periodontitis. 49
Cold-Adaptation Signatures in the Ligand Rebinding Kinetics to the Truncated Hemoglobin of the Antarctic Bacterium Pseudoalteromonas haloplanktis TAC125 49
Zinc-substituted myoglobin is a naturally occurring photoantimicrobial agent with potential applications in food decontamination 49
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity 48
Protein function in the crystalline state probed by polarized absorption microspectrophotometry 48
Modulation of expression and polymerization of hemoglobin Polytaur, a potential blood substitute 47
Tertiary and quaternary effects in the allosteric regulation of animal hemoglobins 47
Regulation of human serine racemase activity and dynamics by halides, ATP and malonate 47
Oxygen and Nitric Oxide Rebinding Kinetics in Nonsymbiotic Hemoglobin AHb1 from Arabidopsis thaliana 45
ENZIMI CATECOLO 1,2 DIOSSIGENASI INCAPSULATI IN GEL DI SILICE E/O DI ORMOSILI, PROCEDIMENTO DI INCAPSULAMENTO DIDETTI ENZIMI IN GEL DI SILICE E/O DI ORMOSILI, ED USO DI DETTI ENZIMI INCAPSULATI PER IL BIORISANAMENTO DI MATERIALICONTAMINATI CON CATECOLI E LORO DERIVATI 45
Nitric Oxide Sensing by a Blue Fluorescent Protein 44
Site-directed mutations of human hemoglobin at residue 35beta: a residue at the intersection of the alpha1beta1, alpha1beta2 and alpha1alpha2 interfaces 44
Oxygen delivery via allosteric effectors of haemoglobin and blood substitutes 44
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism 44
The SoxYZ Complex Carries Sulfur Cycle Intermediates on a Peptide Swinging Arm. 44
Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form 44
Pegylaytion destabilizes the haemoglobin tetramer 43
Structural Bases for the Regulation of CO Binding in the Archaeal Protoglobin from Methanosarcina acetivorans 43
Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases 42
‘Cool’ adaptations to cold environments: globins in Notothenioidei (Actynopterygii, Perciformes) 42
Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro 42
Polymerized and polyethylene glycol-conjugated hemoglobins: A globin-based calibration curve for dynamic light scattering analysis. 42
Totale 6.347
Categoria #
all - tutte 24.634
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.634


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019171 0 0 0 0 0 0 0 0 0 0 163 8
2019/20201.331 228 205 76 20 102 196 170 33 135 73 27 66
2020/2021741 12 73 47 16 122 26 81 26 190 28 79 41
2021/2022609 20 17 9 48 36 32 59 67 29 53 44 195
2022/20232.492 230 231 185 199 234 295 30 151 738 40 119 40
2023/2024882 62 72 40 61 87 284 72 98 33 64 9 0
Totale 7.171