IRIS
BERTONI, Simona
 Distribuzione geografica
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Continente #
EU - Europa 4.244
NA - Nord America 4.103
AS - Asia 1.515
Continente sconosciuto - Info sul continente non disponibili 17
AF - Africa 8
SA - Sud America 8
OC - Oceania 4
Totale 9.899
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Nazione #
US - Stati Uniti d'America 4.022
CN - Cina 1.200
FI - Finlandia 916
IE - Irlanda 798
SE - Svezia 765
IT - Italia 653
UA - Ucraina 447
DE - Germania 340
TR - Turchia 161
GB - Regno Unito 115
CA - Canada 79
SG - Singapore 76
BE - Belgio 57
IN - India 50
AT - Austria 29
NL - Olanda 27
FR - Francia 25
EU - Europa 17
CZ - Repubblica Ceca 16
RO - Romania 13
ES - Italia 12
JP - Giappone 5
PL - Polonia 5
BR - Brasile 4
HK - Hong Kong 4
HU - Ungheria 4
IR - Iran 4
RU - Federazione Russa 4
VN - Vietnam 4
HR - Croazia 3
KR - Corea 3
PH - Filippine 3
SC - Seychelles 3
AU - Australia 2
BG - Bulgaria 2
CH - Svizzera 2
CM - Camerun 2
DK - Danimarca 2
EC - Ecuador 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
PA - Panama 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
TH - Thailandia 2
CL - Cile 1
DZ - Algeria 1
EG - Egitto 1
LU - Lussemburgo 1
MC - Monaco 1
MY - Malesia 1
PK - Pakistan 1
RS - Serbia 1
TW - Taiwan 1
UY - Uruguay 1
ZA - Sudafrica 1
Totale 9.899
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Città #
Dublin 797
Chandler 790
Jacksonville 491
Ann Arbor 383
Dearborn 376
Beijing 262
Ashburn 226
Parma 218
Nanjing 183
Izmir 152
Princeton 138
New York 130
Wilmington 106
Shanghai 103
San Mateo 90
Boardman 80
Hebei 64
Nanchang 62
Toronto 60
Kunming 59
Helsinki 56
Bremen 55
Brussels 54
Jinan 54
Shenyang 49
Woodbridge 43
Guangzhou 41
Changsha 39
Hefei 39
Seattle 36
Des Moines 33
Los Angeles 32
Bangalore 27
Grafing 27
Vienna 27
Auburn Hills 24
Fremont 24
Norwalk 24
Bologna 23
Singapore 23
Tianjin 23
Jiaxing 21
Hangzhou 19
Groningen 18
Milan 17
Zhengzhou 16
Houston 13
Pune 13
West Jordan 13
Modena 12
Haikou 10
Redwood City 10
Brescia 9
Chicago 9
Düsseldorf 9
Ningbo 9
Reggio Emilia 9
Rome 9
Taiyuan 9
Carpi 8
Montegaldella 8
Mordano 8
Redmond 8
Taizhou 8
Falls Church 7
Kocaeli 7
Lanzhou 7
London 7
Madrid 7
Montréal 7
Mestre 6
Neviano degli Arduini 6
Prague 6
Solaro 6
Timisoara 6
Wenzhou 6
Brno 5
Edinburgh 5
Faenza 5
Frankfurt am Main 5
Fuzhou 5
Kraków 5
Naples 5
Rockville 5
Tulsa 5
Xian 5
Altidona 4
Aulla 4
Baotou 4
Chengdu 4
Florence 4
Hanoi 4
Lübeck 4
Mantova 4
Munich 4
Nuremberg 4
Ottawa 4
Palermo 4
Quzhou 4
Rimini 4
Totale 5.972
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Nome #
1,4-dioxane, a suitable scaffold for the development of novel M3 muscarinic receptor antagonists 172
1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5 amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6 carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10Hpyrimido[1,2-a [1,8]naphthyridine-6-carboxamide derivative 163
Targeting the Eph/ephrin system as anti-inflammatory strategy in IBD 152
Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice 142
Antiplatelet and antithrombotic activities of essential oil from wild Ocotea quixos (Lam.) Kosterm. (Lauraceae) calices from Amazonian Ecuador 117
Protective Effects of a Protease Inhibitor (Gabexate Mesilate) on Intestinal Ischemia/Reperfusion Injury in Rats 110
Dibasic biphenyl H(3) receptor antagonists: Steric tolerance for a lipophilic side chain. 104
Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity. 102
Effect of μ Opioid Receptor Activation On Intestinal Ischemia/Reperfusion Injury in Mice 99
Multi-Target CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach 99
Caratterizzazione farmacologica in vitro di nuovi agonisti muscarinici analoghi dell'Oxotremorina 98
Nuovi potenti agonisti muscarinici oxotremorina-M simili a struttura acetilenica: studio funzionale in vitro 98
Adaptive changes in rat ileum motility induced by mild mesenteric ischemia/reperfusion injury: role of endogenous mediators and reperfusion time 96
Impact of S1P mimetics on mesenteric ischemia/reperfusion injury 96
Novel Analgesic Agents Obtained by Molecular Hybridization of Orthosteric and Allosteric Ligands 94
The Role of HB-Donor Groups in the Heterocyclic Polar Fragment of H3-Antagonists. I. Synthesis and Biological Assays 92
Suppression of inflammatory events associated to intestinal ischemia-reperfusion by 5-HT1A blockade in mice 91
1,8-Naphthyridines VII. New substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides and their isosteric analogues, exhibiting notable anti-inflammatory and/or analgesic activities, but no acute gastrolesivity. 90
QSAR study of 2-aminobenzimidazole derivatives as H3 antagonists 88
Histamine H4 receptor antagonism and mesenteric ischemia/reperfusion injury in mice 87
Accommodation and peristalsis are functional responses to chronic obstruction in rat hypertrophic ileum 87
Influence of adenosine in the systemic and local injury caused by mesenteric ischemia-reperfusion in mice 87
Access to CNS of selected H3-antagonists: ex vivo binding study in rats 87
Gastrointestinal symptoms and local oxidative stress in a model of Parkinson's Disease in rats 87
Bifidobacterium bifidum PRL2010 alleviates intestinal ischemia/reperfusioni injury 86
Mesenteric ischemia-reperfusion: an overview of preclinical drug strategies 85
Analgesici-antipiretici benzopirano pirimidinici non acidici attivi per via orale privi di gastrolesività 85
Cognition enhancing effect in rats of a selected histamine H3 receptor antagonist with good brain penetration 83
Daily assumption of fermented milk containing Bifidobacterium breve 246 B® promotes prophylactic effects against intestinal inflammation in mice 83
Dual role of endogenous serotonin in 2,4,6-Trinitrobenzene Sulfonic Acid-induced colitis 82
Motor responses of rat hypertrophic intestine following chronic obstruction 82
1,8-Naphthyridines VIII. Novel 5-aminoimidazo[1,2-a] [1,8]naphthyridine-6-carboxamide and 5-amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamide derivatives showing potent analgesic or anti-inflammatory activity, respectively, and completely devoid of acute gastrolesivity. 82
Validation of a histamine H3 receptor model through structure–activity relationships for classical H3 antagonists 80
Botanicals used as food supplements interfering with EphA2-ephrinA1 system: a screening study 79
Intestinal chronic obstruction affects motor responsiveness of rat hypertrophic longitudinal and circular muscles 78
Synthesis and pharmacological screening of novel non-acidic gastric-sparing antiinflammatory/antiplatelet agents:5-alkyl/cycloalkylamino substituted 2-amino-5H-[1]benzopyrano[4,3-d]pyrimidines 78
Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses 78
CNS access of selected H3-antagonists: ex vivo binding study in rats 77
Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity 77
A promising imidazole-free histamine H3 receptor antagonist with good brain penetration and anticholinesterase activity. 77
Biochemical platform for the identification of adverse effects triggered by free hemoglobin in guinea pigs 76
Influence of Nitric Oxide system in mesenteric ischemia-reperfusion induced injury in mice 76
Multiple approaches for the discovery and development of small molecules targeting Eph-ephrin protein-protein interaction 76
Interactions of new and conventional H3-blockers with non-histaminergic receptors involved in neurogenic and myogenic contractile responses of guinea-pig ileum 75
Analgesic activity of new hybrid muscarinic agonists in mice 75
Synthesis and functional characterization of novel heterocyclic derivatives related to oxotremorine and oxotremorine-M 74
Dibasic non-imidazole histamine H3 receptor antagonists with a rigid byphenyl scaffold. 74
Different role of the Histamine H3 Receptor in Vagal-, Betanechol-, Pentagastrin-induced Gastric Acid Secretion in Anaesthetized Rats 73
New analogues of oxotremorine and oxotremorine-M: estimation of their in vitro affinity and efficacy at muscarinic receptor subtypes 73
Synthesis, biological activity, QSAR and QSPR study of 2/aminobenzimidazole derivatives as potent H3-antagonists 72
Role of Glutamate- N-methyl-D-Aspartate (NMDA) Receptors in Neuronal Plasticity and Gastrointestinal Transit Delay Induced by Ischemia/Reperfusion in Rats 72
Accommodation and peristalsis are functional responses to obstruction in rat hypertrophic ileum 72
Elucidating the gut microbiome of ulcerative colitis: bifidobacteria as novel microbial biomarkers 72
Allosteric Modulation of Muscarinic Acetylcholine-Receptors: Oxotremorine-Phthalimidoalkyl-Hybrids of the Hexamethonio-type 71
Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity. 71
Development of a GPCR model for SAR interpretation of classical and new H3 antagonists 71
Access to CNS of selected H3-antagonists: ex vivo binding study in rats 71
In vitro and in vivo pharmacological analysis of imidazole-free histamine H3 receptor antagonists: promising results for a brain-penetrating H3 blocker with weak anticholinesterase activity. 70
Role of 5-HT in intestinal ischemia-reperfusion: suppression of inflammatory events by 5-HT1A blockade in mice 70
Disruption of Eph-ephrin B signaling pathways mitigates inflammation in a murine model of Crohn’s disease 70
Assessment of intestinal motor responsiveness in an ischemia/reperfusion model in rats 69
Eph/ephrin targeting with a small molecule improves glucose tolerance in healthy and insulin-resistant mice 68
New potent acethylenic muscarinic agonists related to oxotremorine-M: in vitro functional study 68
Indole-based analogs of melatonin: in vitro antioxidant and cytoprotective activities 67
Screening di nuovi agenti antiinfiammatori/antiaggreganti non-acidici: sviluppo di 2-amino-5H-[1]benzopirano[4,3-d]pirimidine 5-alchil/cicloalchilamino sostituite prive di attivita' gastrolesiva 67
Up-regulation of inhibitory transmitters in myenteric neurons of the rat ileum in an acute model of ischemia/reperfusion 67
Radiological analysis of gastrointestinal dysmotility in a model of central nervous dopaminergic degeneration: Comparative study with conventional in vivo techniques in the rat 67
Protection by the EPH-EPHRIN System Against Mesenteric Ischemia-Reperfusion Injury 67
UniPR1331: small Eph/ephrin antagonist beneficial in intestinal inflammation by interfering with type-B signaling 67
Activation of μ opioid receptors ameliorates mucosal injury induced by intestinal ischemia and reperfusion in mice 66
Sviluppo e caratterizzazione farmacologica di un nuovo potente e selettivo H3-bloccante istaminico non-tioureico 66
Dual-Acting Drugs: an in vitro Study of Nonimidazole Histamine H(3) Receptor Antagonists Combining Anticholinesterase Activity 66
Preliminary study of calcium balance and bone mineralization improvement by a new calcium supplement in growing rats 66
Radiological analysis of gastrointestinal dysmotility associated with central dopaminergic impairment in an animal model of parkinson's disease (PD) 65
5-HT1A receptors as target to protect the intestine in an experimental model of colitis 65
Discovery and development of low molecular weight Eph-ephrin protein-protein inhbi-tors endowed with antiangiogenic activity 65
Alterations of intestinal motor responsiveness in a model of mild mesenteric ischemia/reperfusion in rats 65
Imidazole H3-antagonists: Relationship between Structure and Ex-vivo binding to Rat Brain H3-Receptors 65
Functional study of the central access of chemical delivery systems developed as g-aminobutyric acid (GABA) prodrugs 64
RESPONSIVENESS OF LONGITUDINAL AND CIRCULAR MUSCLE TO RELAXING MEDIATORS IS DIFFERENTIALLY AFFECTED IN RAT HYPERTROPHIED ILEUM 64
Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach 63
In vitro characterization of potency, affinity and selectivity of H3-antagonists: from thioperamide to thioperamide unrelated derivatives 63
Synthesis and biological evaluation of new non-imidazole H(3)-receptor antagonists of the 2-aminobenzimidazole series 62
null 61
Inflammatory response and intestinal dismotility caused by experimental ischemia/reperfusion injury in rats: possible involvement of NMDA receptors 61
The selective inhibition of inducible nitric oxide synthase prevents intestinal ischemia-reperfusion injury in mice 61
Pegylation promotes hemoglobin tetramer dissociation 61
Discovery of histamine H3 receptor antagonistic property of simple imidazole-free derivatives: preliminary pharmacological investigation. 61
Orally active non-acidic analgesic-antipyretic benzopyranopyrimidines devoided of gastrolesivity 61
Δ5-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system 61
PHARMACOLOGICAL CHARACTERIZATION OF NEW COMPOUNDS AIMED AT INHIBITING EPH-EPHRIN INTERACTION IN GLIOBLASTOMA 60
Investigation on the anti-inflammatory properties of Ocotea quixos Lam. essential oil. 60
Functional plasticity of rat intestine after removal of chronic mechanical obstruction 59
Synthesis and in vitro pharmacology of novel heterocyclic muscarinic ligands 59
Pharmacological characterization of new antiplatelet benzopyrano[4,3-d]pyrimidines 59
Involvement of 5-HT2A receptors in motor and inflammatory disorders induced by mesenteric ischemia reperfusion in mice 59
Multi-target-directed ligands: new histamine H3 receptor antagonists with anticholinesterase activity 59
Preventive effect of 5-HT1A receptor agonist Buspirone on mesenteric ischemia/reperfusion-induced inflammatory injuries in mice 59
Development of inhalation powders containing lactic acid bacteria with antimicrobial activity against Pseudomonas aeruginosa 58
NMDA glutamate receptor activation mediates the effects of ischemia/reperfusion on gastrointestinal transit and neuronal phenotypes in the rat myenteric plexus 58
Totale 7.813
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Categoria #
all - tutte 31.154
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.154
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019234 0 0 0 0 0 0 0 0 0 0 209 25
2019/20202.110 307 266 131 57 182 286 284 52 188 169 68 120
2020/20211.027 21 117 98 33 151 41 130 28 201 43 140 24
2021/2022836 32 23 32 91 51 56 94 104 33 58 58 204
2022/20233.138 347 320 181 234 320 344 67 174 932 45 121 53
2023/20241.045 69 80 46 47 88 313 126 84 38 66 88 0
Totale 10.039