IRIS
BETTATI, Stefano
 Distribuzione geografica
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Continente #
NA - Nord America 9.921
AS - Asia 7.661
EU - Europa 5.709
SA - Sud America 1.100
Continente sconosciuto - Info sul continente non disponibili 392
AF - Africa 354
OC - Oceania 12
Totale 25.149
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Nazione #
US - Stati Uniti d'America 9.652
SG - Singapore 2.589
CN - Cina 2.091
IT - Italia 1.249
VN - Vietnam 1.156
BR - Brasile 874
IE - Irlanda 801
SE - Svezia 737
FI - Finlandia 690
HK - Hong Kong 579
DE - Germania 541
UA - Ucraina 406
BD - Bangladesh 339
FR - Francia 281
ZA - Sudafrica 231
NL - Olanda 225
GB - Regno Unito 200
TR - Turchia 199
CA - Canada 159
RU - Federazione Russa 139
AT - Austria 117
IN - India 117
KR - Corea 117
AR - Argentina 80
IQ - Iraq 68
JP - Giappone 61
ID - Indonesia 59
ES - Italia 53
BE - Belgio 52
MX - Messico 44
PL - Polonia 44
PK - Pakistan 41
CZ - Repubblica Ceca 39
EC - Ecuador 39
PH - Filippine 37
CI - Costa d'Avorio 32
CO - Colombia 29
TH - Thailandia 27
LT - Lituania 21
SA - Arabia Saudita 21
UZ - Uzbekistan 21
VE - Venezuela 21
CH - Svizzera 20
MA - Marocco 20
CR - Costa Rica 17
IR - Iran 17
JM - Giamaica 17
KE - Kenya 17
TW - Taiwan 16
CL - Cile 15
RO - Romania 15
PE - Perù 14
EG - Egitto 13
IL - Israele 13
DZ - Algeria 11
JO - Giordania 11
MY - Malesia 10
PY - Paraguay 10
UY - Uruguay 10
AE - Emirati Arabi Uniti 9
LU - Lussemburgo 9
AZ - Azerbaigian 8
HN - Honduras 8
PT - Portogallo 8
TN - Tunisia 8
BG - Bulgaria 7
BO - Bolivia 7
ET - Etiopia 7
KZ - Kazakistan 7
AL - Albania 6
AU - Australia 6
EU - Europa 6
GT - Guatemala 6
NP - Nepal 6
PS - Palestinian Territory 6
RS - Serbia 6
AM - Armenia 5
BY - Bielorussia 5
HR - Croazia 5
LB - Libano 5
MD - Moldavia 5
DK - Danimarca 4
DO - Repubblica Dominicana 4
KG - Kirghizistan 4
MN - Mongolia 4
NZ - Nuova Zelanda 4
OM - Oman 4
SI - Slovenia 4
CY - Cipro 3
GA - Gabon 3
HU - Ungheria 3
LV - Lettonia 3
MT - Malta 3
NI - Nicaragua 3
TT - Trinidad e Tobago 3
BN - Brunei Darussalam 2
BZ - Belize 2
CG - Congo 2
DM - Dominica 2
EE - Estonia 2
Totale 24.728
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Città #
Singapore 1.312
Ashburn 1.173
San Jose 901
Chandler 878
Dublin 795
Santa Clara 652
Dallas 571
Hong Kong 544
Beijing 461
Jacksonville 412
Parma 402
Ann Arbor 382
Council Bluffs 370
Ho Chi Minh City 338
Dearborn 304
Hanoi 283
Boardman 240
New York 240
Johannesburg 218
Nanjing 202
Los Angeles 195
Shanghai 163
Princeton 152
Lauterbourg 150
Izmir 143
Chicago 137
Hefei 131
Wilmington 121
Munich 114
Buffalo 103
San Mateo 99
Bremen 94
The Dalles 94
Seoul 92
Vienna 92
Columbus 81
São Paulo 79
Milan 78
Moscow 71
Toronto 68
Helsinki 65
Shenyang 60
Jinan 58
Woodbridge 55
Kunming 53
Marseille 53
Brussels 51
Rome 50
Turku 50
Hillsboro 49
Seattle 49
Da Nang 46
Hebei 46
Tokyo 44
Nanchang 42
Guangzhou 41
Haiphong 41
Changsha 40
Jakarta 39
Bologna 38
Tianjin 38
Frankfurt am Main 35
Nuremberg 35
Warsaw 34
London 33
Abidjan 32
Houston 32
San Francisco 32
Brooklyn 31
Des Moines 31
Phoenix 30
Baghdad 29
Grafing 28
Rio de Janeiro 28
Atlanta 27
Falls Church 27
Orem 27
Brno 26
Fremont 25
Jiaxing 23
Hải Dương 21
Modena 21
Auburn Hills 20
Dong Ket 20
Montreal 20
Belo Horizonte 19
Chennai 19
Denver 19
Leawood 19
Fidenza 18
Tashkent 18
Biên Hòa 17
Brasília 17
Elora 17
Nairobi 17
Ottawa 17
Stockholm 17
Turin 16
Curitiba 15
Memphis 15
Totale 14.870
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Nome #
Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants 268
High and low oxygen affinity conformations of T state hemoglobin 265
Combination of SAXS and protein painting discloses the three-dimensional organization of the bacterial cysteine synthase complex, a potential target for enhancers of antibiotic action 248
Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP 246
Identification of small molecules affecting the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore 244
Tryptophan synthase: a mine for enzymologists 227
PARMA CITTÀ FUTURA VOLUME II Il libro bianco 223
Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant 219
Dynamics of Green Fluorescent Protein Mutant2 in Solution, on Spin-coated Glasses and Encapsulated in Wet Silica Gels 217
Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution 213
Allosteric communication of tryptophan synthase: functional and regulatory properties of the betaSer178Pro mutant 212
Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor 209
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase 208
Exploring the chemical space around N-(5-nitrothiazol-2-yl)-1,2,3-thiadiazole-4-carboxamide, a hit compound with serine acetyltransferase (SAT) inhibitory properties 207
Kinetics of acid-induced spectral changes in GFPmut2 chromophore 206
Catalysis and Structure of Zebrafish Urate Oxidase Provide Insights into the Origin of Hyperuricemia in Hominoids 205
Cysteine Enrichment Mediates Co-Option of Uricase in Reptilian Skin and Transition to Uricotelism 202
Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms 199
A Key Silencing Histone Mark on Chromatin Is Lost When Colorectal Adenocarcinoma Cells Are Depleted of Methionine by Methionine γ-Lyase 199
From hemoglobin allostery to hemoglobin-based oxygen carriers 198
A competitive o‐acetylserine sulfhydrylase inhibitor modulates the formation of cysteine synthase complex 195
Nuovi composti antimicrobici 195
Functional Characterization of Heme Proteins Encapsulated in Wet Nanoporous Silica Gels 194
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme 193
Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria 192
Pyridoxal 5’-Phosphate-Dependent Enzymes: Catalysis, Conformation and Genomics 192
Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy 192
Post-Translational Modifications of Histone Variants in the Absence and Presence of a Methionine-Depleting Enzyme in Normal and Cancer Cells 191
Identification of the Geometric Requirements for the Allosteric Communication between Alpha and Beta Subunits of Tryptophan Synthase 191
Fluorescence quantification of allantoin in biological samples by cap-immobilized allantoinase/resorcinol assay 188
Diatom Allantoin Synthase Provides Structural Insights into Natural Fusion Protein Therapeutics 188
Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction 188
Conjugation to gold nanoparticles of methionine gamma-lyase, a cancer-starving enzyme. Physicochemical characterization of the nanocomplex for prospective nanomedicine applications 184
Rational Design, Synthesis and Preliminary Structure-Activity Relationships of α-Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella Typhimurium O-Acetylserine Sulfhydrylase 182
Biocatalysis in a confined environment. Lessons from enzymes immobilized in wet, nanoporous silica gels 178
Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor 178
Genetically Encoded Biosensors for the Fluorescence Detection of O2 and Reactive O2 Species 177
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels 177
A two-step process controls the formation of the bienzyme cysteine synthase complex 175
Cryo-EM undiscloses structural and mechanistic details on iron hijacking by Staphylococcus aureus: An insight into the interaction of IsdB hemophore with human hemoglobin 174
Geminate rebinding in R state hemoglobin: kinetic and computational evidence for multiple hydrophobic pockets 174
SP-B and SP-C analogues within CHF5633 synthetic surfactant probed by fluorescence labeling 171
Role of pyridoxal 5’-phosphate in the structural stabilization of O-acetylserine sulfhydrylase 170
Lung metastasis resection of adenoid cystic carcinoma of salivary glands 169
Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy 169
Human Serine Racemase Weakly Binds the Third PDZ Domain of PSD-95 168
Allosteric communication between alpha and beta subunits of tryptophan synthase: modelling the open-closed transition of the alpha subunit 168
Evidence for Two Geminate Rebinding States Following Laser Photolysis of R State Hemoglobin Encapsulated in Wet Silica Gels 168
A Trivalent Enzymatic System for Uricolytic Therapy of HPRT Deficiency and Lesch-Nyhan Disease 167
Structural insight into the interaction of O-acetylserine sulfhydrylase with competitive, peptidic inhibitors by Saturation Transfer Difference-NMR 167
Allosteric regulation of tryptophan synthase: a pKa change at the beta-active site induced by alpha-subunit ligands 166
Biochemical platform for the identification of adverse effects triggered by free hemoglobin in guinea pigs 164
Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality 164
CO rebinding kinetics to high and low affinity T state hemoglobin encapsulated in silica gels 163
Chemistry and biochemistry of oxygen therapeutics: from transfusion to artificial blood 163
Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR 163
CO rebinding kinetics to myoglobin- and R state hemoglobin-doped silica gels in the presence of glycerol 161
Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase 161
Surface-exposed Tryptophan Residues Are Essential for O-Acetylserine Sulfhydrylase Structure, Function and Stability 156
Blocking cysteine biosynthesis in Salmonella typhimurium: the moonlighting enzyme CysK as a potential antibiotic target 156
Conformational probes of O-acetylserine sulfhydrylase:fluorescence of tryptophans 50 and 161 154
Iron metabolism at the interface between host and pathogen: From nutritional immunity to antibacterial development 154
Allosteric regulation of tryptophan synthase: effects of pH, temperature and alpha-subunit ligands on the equilibrium distribution of pyridoxal 5'-phosphate L-serine intermediates 154
Use of Exogenous Enzymes in Human Therapy: Approved Drugs and Potential Applications 154
Design of O-acetylserine sulfhydrylase inhibitors by mimicking Nature. 153
Time-resolved X-ray solution scattering unveils the events leading to hemoglobin heme capture by staphylococcal IsdB 152
Correlation of protein functional properties in the crystal and in solution: the case study of T state hemoglobin 152
More than a Confinement: “Soft” and “Hard” Enzyme Entrapment Modulates Biological Catalyst Function 152
Nanoscale dynamical investigation of the hemoglobin complex with the bacterial protein IsdB: is their interaction stabilized by catch bonds? 151
Longitudinal blood immune-inflammatory and radiomic profiling to decode different patterns acquired resistance to immunotherapy in patients with NSCLC 151
The molecular pathway for the allosteric regulation of tryptophan synthase 150
High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model 149
Insight into GFPmut2 pH Dependence by Single Crystal Microspectrophotometry and X-ray Crystallography 149
Interaction of human hemoglobin and semi-hemoglobins with the Staphylococcus aureus hemophore IsdB: a kinetic and mechanistic insight 148
New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels. 146
First-in-class inhibitors of SbnA reduce siderophore production in Staphylococcus aureus 145
pH Dependence of Tryptophan Synthase Catalytic Mechanism: I. The first stage, the beta-elimination reaction 144
Investigation of hemoglobin conformational structure changes performed with Mössbauer spectroscopy 141
Immobilization of allantoinase for the development of an optical biosensor of oxidative stress states 140
T State Hemoglobin Binds Oxygen Noncooperatively with Allosteric Effects of Protons, Inositol Hexaphosphate, and Chloride 139
Effect of the point mutation H148G on GFPmut2 unfolding kinetics by fluorescence spectroscopy 139
Exercise capacity assessment in patients undergoing lung resection 139
Modulation of Escherichia coli serine acetyltransferase catalytic activity in the cysteine synthase complex 139
The value of lung metastases resection from adenoid cystic carcinoma 138
A Tertiary Two-state Allosteric Model for Hemoglobin 138
Allosteric Mechanism of Haemoglobin: Rupture of Salt-bridges Raises the Oxygen Affinity of T-structure 138
Hemocyanin from E. californicum encapsulated in silica gels: oxygen binding and conformational states 138
Unfolding of pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence 138
The multifaceted pyridoxal 5’-phosphate-dependent O-acetylserine sulfhydrylase 137
Understanding iron hijacking by Staphylococcus aureus: a structural and mechanistic insight into the interaction of IsdB hemophore with human hemoglobin 134
Selective stabilization of different GFP Mut2 conformations at alkaline and acidic pH 134
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions 134
Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: Evidence from fluorescence spectroscopy 131
Cooperative oxygen binding to Scapharca inaequivalvis hemoglobin in the crystal 131
Thoracoscopic parietal pleural argon beam coagulation versus pleural abrasion in the treatment of primary spontaneous pneumothorax. 131
Fisica biomedica - Per i Corsi di Laurea Magistrale in Medicina e Chirurgia, Odontoiatria, Medicina Veterinaria, Farmacia, Scienze e Tecnologie Farmaceutiche, Corsi di Laurea nelle Professioni Sanitarie e in Scienze delle Attività Motorie 130
Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state 130
Protein encapsulation, conformations, and nanobiotools 129
Pyridoxal 5’-phosphate enzymes as targets for terapeutic agents 128
Protein Structure-Function Relationship Studied by Single Crystal Polarized Absorption Microspectrophotometry 127
Totale 17.108
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Categoria #
all - tutte 87.540
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 87.540
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.000 0 27 18 96 33 88 119 114 80 60 104 261
2022/20233.317 351 337 234 269 370 390 36 199 968 21 105 37
2023/20241.369 67 120 45 41 93 321 131 106 47 75 100 223
2024/20254.277 131 226 329 251 418 559 243 242 383 345 406 744
2025/202610.119 962 823 1.384 842 1.218 488 1.115 367 1.178 716 620 406
2026/2027584 257 327 0 0 0 0 0 0 0 0 0 0
Totale 25.149