IRIS
PIERONI, Marco
 Distribuzione geografica
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Continente #
NA - Nord America 1.444
EU - Europa 1.144
AS - Asia 649
AF - Africa 32
OC - Oceania 2
SA - Sud America 2
Totale 3.273
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Nazione #
US - Stati Uniti d'America 1.431
CN - Cina 380
IE - Irlanda 292
IT - Italia 277
SE - Svezia 225
SG - Singapore 126
FI - Finlandia 112
TR - Turchia 93
DE - Germania 76
AT - Austria 43
CI - Costa d'Avorio 28
CZ - Repubblica Ceca 19
BE - Belgio 18
GB - Regno Unito 18
FR - Francia 17
IN - India 16
NL - Olanda 15
KR - Corea 12
CA - Canada 8
LU - Lussemburgo 8
ES - Italia 7
HK - Hong Kong 4
PK - Pakistan 4
ID - Indonesia 3
PA - Panama 3
TW - Taiwan 3
UA - Ucraina 3
VN - Vietnam 3
AU - Australia 2
CH - Svizzera 2
EG - Egitto 2
GH - Ghana 2
PL - Polonia 2
SI - Slovenia 2
BG - Bulgaria 1
BR - Brasile 1
CL - Cile 1
CY - Cipro 1
HN - Honduras 1
HR - Croazia 1
IR - Iran 1
JP - Giappone 1
LT - Lituania 1
ME - Montenegro 1
MX - Messico 1
MY - Malesia 1
NO - Norvegia 1
NP - Nepal 1
PT - Portogallo 1
RU - Federazione Russa 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 3.273
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Città #
Chandler 339
Dublin 290
Ann Arbor 146
Ashburn 99
Singapore 93
Parma 82
Boardman 78
Dearborn 72
Izmir 72
Shanghai 67
Nanjing 61
Princeton 57
Beijing 56
Helsinki 45
Wilmington 43
Bremen 40
Vienna 35
Abidjan 28
Chicago 26
Kocaeli 21
New York 19
San Mateo 18
Hefei 17
Nanchang 17
Falls Church 16
Hebei 16
Santa Clara 16
Shenyang 16
Brussels 15
Milan 15
Changsha 14
Guangzhou 14
Jinan 13
Seattle 13
Brno 12
Jiaxing 12
Norwalk 12
Los Angeles 11
Houston 9
Bologna 8
Dallas 8
Des Moines 8
Fremont 8
Dalmine 6
Sassari 6
Woodbridge 6
Birmingham 5
Fairfield 5
Luxembourg 5
Modena 5
New Brunswick 5
Ningbo 5
Chongqing 4
Dordrecht 4
Haikou 4
Kunming 4
London 4
Pune 4
San Giuliano Milanese 4
Washington 4
Zhengzhou 4
Ahmedabad 3
Amstelveen 3
Bandung 3
Beitou 3
Edinburgh 3
Florence 3
Gonzaga 3
Grafing 3
Gwanak-gu 3
Lucca 3
Ottawa 3
Panama City 3
Rockville 3
Rome 3
Sissa 3
Uppsala 3
Ancona 2
Angers 2
Antwerpen 2
Basel 2
Brisbane 2
Cairo 2
Carpi 2
Chengdu 2
Chiniot 2
Daejeon 2
Dong Ket 2
Evanston 2
Figline Valdarno 2
Formigine 2
Gijón 2
Hangzhou 2
Hong Kong 2
Huizhou 2
Kyiv 2
Lanzhou 2
Lattes 2
Ljubljana 2
Maddaloni 2
Totale 2.235
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Nome #
Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants 142
Nuovi composti antimicrobici 138
Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant 104
Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases 89
Integration of Enhanced Sampling Methods with Saturation Transfer Difference Experiments to Identify Protein Druggable Pockets 87
Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms 85
Rational Design, Synthesis and Preliminary Structure-Activity Relationships of α-Substituted-2-Phenylcyclopropane Carboxylic Acids as Inhibitors of Salmonella Typhimurium O-Acetylserine Sulfhydrylase 83
Discovery of antitubercular 2,4-diphenyl-1H-imidazoles from chemical library repositioning and rational design 80
Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor 77
Inhibitors of the sulfur assimilation pathway in bacterial pathogens as enhancers of antibiotic therapy 75
Antituberculosis agents: Beyond medicinal chemistry rules 74
A competitive o‐acetylserine sulfhydrylase inhibitor modulates the formation of cysteine synthase complex 74
Exploring the chemical space around N-(5-nitrothiazol-2-yl)-1,2,3-thiadiazole-4-carboxamide, a hit compound with serine acetyltransferase (SAT) inhibitory properties 71
Aspergillus fumigatus tryptophan metabolic route differently affects host immunity 71
Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target 70
Sodium Hyaluronate Nanocomposite Respirable Microparticles to Tackle Antibiotic Resistance with Potential Application in Treatment of Mycobacterial Pulmonary Infections 69
Blocking cysteine biosynthesis in Salmonella typhimurium: the moonlighting enzyme CysK as a potential antibiotic target 67
Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation 65
Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria 64
Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR 62
Accepting the Invitation to Open Innovation in Malaria Drug Discovery: Synthesis, Biological Evaluation, and Investigation on the Structure-Activity Relationships of Benzo[b]thiophene-2-carboxamides as Antimalarial Agents 61
Design, Synthesis and Investigation onthe Structure–Activity Relationships of N-Substituted 2-Aminothiazole Derivatives as Antitubercular Agents 60
Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases 60
Adjuvant therapies against tuberculosis: discovery of a 2-aminothiazole targeting Mycobacterium tuberculosis energetics 57
Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery 57
Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design 57
Further insights into the SAR of α-substituted cyclopropylamine derivatives as inhibitors of histone demethylase KDM1A 56
Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase 55
Cycloserine enantiomers are reversible inhibitors of human alanine:glyoxylate aminotransferase: Implications for Primary Hyperoxaluria type 1 54
Sodium Hyaluronate Microparticles for Pulmonary Delivery of Anti-mycobacterial Drugs 53
In vitro digestion of zingiber officinale extract and evaluation of stability as a first step to determine its bioaccesibility 53
Towards the sustainable discovery and development of new antibiotics 52
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin 49
Biochemical characterization of Aspergillus fumigatus AroH, a putative aromatic amino acid aminotransferase 46
2-Aminooxazole as a Novel Privileged Scaffold in Antitubercular Medicinal Chemistry 46
Discovery of New Potential Anti-Infective Compounds Based on Carbonic Anhydrase Inhibitors by Rational Target-Focused Repurposing Approaches 45
Derivatives of 3-isoxazolecarboxylic acid esters - a potent and selective compound class against replicating and nonreplicating Mycobacterium tuberculosis 45
Preliminary structure - Activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant Mycobacterium tuberculosis strains 45
6-Hydrogen-8-Methylquinolones Active Against Replicating and Non-replicating Mycobacterium tuberculosis 45
Challenging the drug-likeness dogma for new drug discovery in Tuberculosis 45
Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1 41
Synthesis of 7-desmethyl analogs of (+)- and (-)-huperzine A 41
Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds: a patent evaluation of US2019343869(A1) 41
Modulation of bacterial metabolism by the microenvironment controls MAIT cell stimulation article 40
Rational Design and Synthesis of Thioridazine Analogues as Enhancers of the Antituberculosis Therapy 39
From 6-aminoquinolone antibacterials to 6-amino-7- thiopyranopyridinylquinolone ethyl esters as inhibitors of staphylococcus aureus multidrug efflux pumps 38
Structural analogs of huperzine A improve survival in guinea pigs exposed to soman 36
An Experimental Model for the Rapid Screening of Compounds with Potential Use Against Mycobacteria 35
Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit–to–lead optimization and release of a novel antitubercular chemotype via scaffold derivatization 30
Indoleamides are active against drug-resistant mycobacterium tuberculosis 30
Pyrido[1,2-a]benzimidazole-Based Agents Active Against Tuberculosis (TB), Multidrug-Resistant (MDR) TB and Extensively Drug-Resistant (XDR) TB 30
Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains 30
NOC chemistry for tuberculosis - Further investigations on the structure-activity relationships of antitubercular isoxazole-3-carboxylic acid ester derivatives 30
Synthesis and Structure-Activity Relationships of Lansine Analogues as Antileishmanial Agents 29
Searching for innovative quinolone-like scaffolds: Synthesis and biological evaluation of 2,1-benzothiazine 2,2-dioxide derivatives 27
From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters 27
Spectinamides: A challenge, a proof, and a suggestion 26
Mutation of Rv2887, a marR-Like gene, confers mycobacterium tuberculosis resistance to an imidazopyridine-based agent 25
Novel N-benzoyl-2-hydroxybenzamide disrupts unique parasite secretory pathway 25
Synthesis, biological evaluation, and structure-activity relationships of N -benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), trypanosomes, and leishmania 24
Rational design of 5-phenyl-3-isoxazolecarboxylic acid ethyl esters as growth inhibitors of Mycobacterium tuberculosis. A potent and selective series for further drug development 22
Synthesis, biological evaluation, and structure-activity relationships for 5-[(E)-2-arylethenyl]-3-isoxazolecarboxylic acid alkyl ester derivatives as valuable antitubercular chemotypes 21
In pursuit of natural product leads: Synthesis and biological evaluation of 2-[3-hydroxy-2-[(3-hydroxypyridine-2-carbonyl)amino]phenyl]benzoxazole-4- carboxylic acid (A-33853) and its analogues: Discovery of N-(2-benzoxazol-2- ylphenyl)benzamides as novel antileishmanial chemotypes 20
Preliminary structure−activity relationships analysis on N-(3,5-dichlorophenyl)-4,5-dihydronaphtho[1,2-d]thiazol-2-amine, a disruptor of mycobacterial energetics 18
Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor 11
Totale 3.424
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Categoria #
all - tutte 15.695
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.695
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020281 0 0 3 7 42 74 47 8 27 49 17 7
2020/2021201 3 5 8 10 6 12 8 24 46 41 17 21
2021/2022379 15 28 25 25 10 38 20 26 35 22 21 114
2022/20231.261 118 138 79 100 146 149 7 65 374 15 41 29
2023/2024507 24 40 17 28 49 72 48 44 26 28 40 91
2024/2025265 64 90 111 0 0 0 0 0 0 0 0 0
Totale 3.424