The growing area has a substantial effect on plants, affecting secondary metabolism. In hops, different authors studied the effect of growing area on the chemical composition of cones with the aim of verifying and understanding the changes in hop characters. Despite the scant literature the subject receives an increasing attention by brewers and hop growers. The present study aimed to characterize with gas chromatography-mass spectrometry (GC-MS), and HPLC-UV, cones of hop (Humulus lupulus L.) cultivar Cascade. Plant material was obtained from 9 different areas of Italy and compared with Cascade samples grown in USA, Germany and Slovenia.
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