IRIS
ZANARDI, Franca
 Distribuzione geografica
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Continente #
NA - Nord America 12.957
AS - Asia 8.319
EU - Europa 6.574
SA - Sud America 1.102
AF - Africa 383
Continente sconosciuto - Info sul continente non disponibili 262
OC - Oceania 5
AN - Antartide 1
Totale 29.603
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Nazione #
US - Stati Uniti d'America 12.659
SG - Singapore 2.880
CN - Cina 2.243
IT - Italia 1.375
VN - Vietnam 1.320
IE - Irlanda 994
SE - Svezia 942
FI - Finlandia 866
BR - Brasile 852
DE - Germania 750
HK - Hong Kong 674
UA - Ucraina 447
TR - Turchia 327
NL - Olanda 269
ZA - Sudafrica 255
FR - Francia 252
IN - India 234
GB - Regno Unito 169
CA - Canada 168
RU - Federazione Russa 139
BD - Bangladesh 127
AR - Argentina 95
ES - Italia 75
MX - Messico 68
IQ - Iraq 65
KR - Corea 60
JP - Giappone 58
BE - Belgio 52
EC - Ecuador 51
DK - Danimarca 48
PL - Polonia 43
AT - Austria 40
PH - Filippine 39
MA - Marocco 34
PK - Pakistan 33
ID - Indonesia 32
VE - Venezuela 28
CO - Colombia 27
IR - Iran 26
TH - Thailandia 25
EG - Egitto 24
CZ - Repubblica Ceca 21
UZ - Uzbekistan 19
RO - Romania 17
TW - Taiwan 17
CL - Cile 16
JO - Giordania 16
KE - Kenya 15
LT - Lituania 14
PY - Paraguay 14
JM - Giamaica 13
MY - Malesia 12
PA - Panama 12
CI - Costa d'Avorio 11
CR - Costa Rica 11
IL - Israele 11
KZ - Kazakistan 11
NP - Nepal 11
CH - Svizzera 10
SA - Arabia Saudita 10
TN - Tunisia 10
BH - Bahrain 9
DZ - Algeria 9
EU - Europa 9
AE - Emirati Arabi Uniti 8
AZ - Azerbaigian 8
ET - Etiopia 8
LB - Libano 8
PE - Perù 8
SK - Slovacchia (Repubblica Slovacca) 8
GT - Guatemala 7
BO - Bolivia 6
OM - Oman 6
PS - Palestinian Territory 6
RS - Serbia 5
TT - Trinidad e Tobago 5
AL - Albania 4
AU - Australia 4
BG - Bulgaria 4
DO - Repubblica Dominicana 4
HN - Honduras 4
PT - Portogallo 4
UY - Uruguay 4
AM - Armenia 3
AO - Angola 3
BY - Bielorussia 3
CY - Cipro 3
GR - Grecia 3
HR - Croazia 3
KW - Kuwait 3
MD - Moldavia 3
SC - Seychelles 3
SN - Senegal 3
SY - Repubblica araba siriana 3
BB - Barbados 2
CG - Congo 2
GE - Georgia 2
HU - Ungheria 2
LK - Sri Lanka 2
LU - Lussemburgo 2
Totale 29.319
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Città #
Dallas 3.707
Singapore 1.348
Ashburn 1.112
Chandler 1.015
Dublin 988
San Jose 905
Hong Kong 635
Beijing 613
Jacksonville 602
Santa Clara 564
Ho Chi Minh City 390
Parma 384
Council Bluffs 370
Ann Arbor 323
Hanoi 312
Dearborn 288
Izmir 271
Boardman 270
Johannesburg 239
Nanjing 220
Princeton 205
Lauterbourg 194
Los Angeles 175
Munich 171
New York 143
San Mateo 143
Helsinki 133
Shanghai 130
Wilmington 127
Hefei 107
Buffalo 91
Moscow 85
Toronto 84
Milan 79
Shenyang 77
Des Moines 75
Frankfurt am Main 75
São Paulo 75
Nanchang 70
Bologna 69
Bremen 69
Pune 68
Columbus 58
Seattle 57
Hebei 54
Da Nang 53
Jinan 53
Changsha 49
Vigevano 49
Woodbridge 49
Brussels 47
Tianjin 47
Haiphong 46
Seoul 44
Guangzhou 43
Kunming 43
Modena 42
Aarhus 40
Rio de Janeiro 37
Houston 35
Tokyo 35
Chicago 32
Chennai 31
Jiaxing 30
Vienna 30
Warsaw 30
Brooklyn 29
Rome 29
Fremont 27
Orem 27
Biên Hòa 26
Leawood 26
Montreal 26
Atlanta 25
Mumbai 24
Phoenix 24
The Dalles 24
Turku 24
Zhengzhou 24
Nuremberg 22
Reggio Emilia 22
Baghdad 21
Amsterdam 20
Ardea 20
Brescia 20
San Francisco 20
Belo Horizonte 19
Florence 19
London 19
Quito 19
Augusta 18
Boston 18
Guayaquil 18
Segrate 18
Tashkent 18
Jakarta 17
Mexico City 17
Norwalk 17
Piacenza 17
Redwood City 17
Totale 18.766
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Nome #
The 1,4- and 1,6-Addition of Vinylogous Donor Systems in on-Water and Organocatalyzed Reactions 1.654
Turning the Imidazole Core into Three‐Dimensional Ring Systems: Mild Organocatalytic Entry to Enantiopure 6,7‐Dihydrobenzimidazoles 635
Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung Cancer 634
Harnessing Vinylogy with Radicals: Photoinduced γ-Benzylation Reactions of 2-Silyloxyfurans 602
The Chiral 5,6-Cyclohexane-fused Uracil Ring-System: a Molecular Platform with Promising Activity against SARS-CoV-2 600
Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interface 572
Catalytic, Asymmetric Vinylogous Mukaiyama Aldol Reactions of Pyrrole- and Furan-Based Dienoxy Silanes: How the Diene Heteroatom Impacts Stereocontrol 230
Direct, Asymmetric Synthesis of Carbocycle-Fused Uracils via [4+2] Cycloadditions: a Noncovalent Organocatalysis Approach 230
Shifting Towards αVβ6 Integrin Ligands Using Novel Aminoproline-Based Cyclic Peptidomimetics 225
Grafting Aminocyclopentane Carboxylic Acids onto the RGD Tripeptide Sequence Generates Low Nanomolar alfaVbeta3/alfaVbeta5 Integrin Dual Binders 217
(2S,4R)-4-fluoroglutamine is converted into (2S,4R)-4-fluoroglutamate by glutaminase activity and may be exploited as a PET tracer in glutamine-addicted cancers 214
Integrin-targeted AmpRGD sunitinib liposomes as integrated antiangiogenic tools 213
[18F](2S,4R)-4-Fluoroglutamine as a New Positron Emission Tomography Tracer in Myeloma 210
Identificazione spettrometrica di composti organici 208
3-Alkylidene-2-oxindoles in Vinylogous Mukaiyama Mannich Reactions: Synthesis of Multifaceted Aminated Scaffolds 206
New Developments of the Principle of Vinylogy as Applied to π-Extended Enolate-Type Donor Systems 204
Cell-targeted c(AmpRGD)-sunitinib molecular conjugates impair tumor growth of melanoma 195
(E)-3-(Alkoxycarbonyl-2-Alkyliden)-2-Oxindoles: Multidentate Pronucleophiles for the Organocatalytic, Vinylogous Michael Addition to Nitroolefins 193
Unlocking Access to Enantiopure Fused Uracils by Chemodivergent [4+2] Cross‐Cycloadditions: DFT‐Supported Homo‐Synergistic Organocatalytic Approach 185
Advances in Exploring Heterocyclic Dienoxysilane Nucleophiles in Asymmetric Synthesis 179
Ciclopeptidi Ibridi Contenenti Amminoacidi Cicloalcanici, e Loro Preparazione ed Uso 177
Mechanistic Insights into the Stepwise (4+2) Cycloaddition toward Chiral Fused Uracil Derivatives 176
Acetaldehyde Silyl Enol Ethers in Enantioselective Mukaiyama Aldol Reactions: Enzyme-Like Organocatalysis in Action 176
AmpRGD-Functionalized Liposomes: From Targeted Delivery Vehicles to Integrated Targeted Antiangiogenic Tools 174
3-Alkenyl-2-silyloxyindoles: An Enabling, Yet Understated Progeny of Vinylogous Carbon Nucleophiles 166
3‑Alkenyl-2-silyloxyindoles in Vinylogous Mannich Reactions: Synthesis of Aminated Indole-Based Scaffolds and Products. 166
Novel RGD-based integrin targeted agents for selective in vivo cancer imaging 166
A ONE-POT ENTRY TO A NOVEL 3-H-BENZO[D]PYRAZOLO[1,5-B]ISOTHIAZOLE RING SYSTEM. 164
A new stereoselective entry to novel, chiral fused-carbocycle uracils 164
Organocatalytic, Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Cyclohexadiene-Embedding Linear and Angular Polycycles 161
A New, Enantioselective Entry to Cycloheptane Amino Acid Polyols 161
Towards new small-molecule peptidomimetics as potent and selective αvβ6 integrin ligands 160
RGD Peptide-Drug Conjugates as Effective Dual Targeting Platforms: Recent Advances 160
Direct, asymmetric synthesis of carbocycle-fused uracils via [4+2] cycloadditions: a noncovalent organocatalysis approach 160
An expeditious procedure for catalytic enantioselective three-component vinylogous Mukaiyama Mannich reactions 158
4-Aminoproline-Based Arginine-Glycine-Aspartate Integrin Binders with Exposed Ligation Points: Practical in-Solution Synthesis, Conjugation and Binding Affinity Evaluation 158
Nintedanib-αVβ3 Integrin Ligand Dual-Targeting Conjugates towards Precision Treatment of Melanoma 155
Exploiting the Distal Reactivity of Indolyl- methylenemalononitriles: an Asymmetric Organocatalyzed [4+2] Cycloaddition with Enals Enables the Assembly of Elusive Dihydrocarbazoles 153
ACCESSING CHIRAL DIHYDRO- AND TETRAHYDROQUINAZOLINE-2,4-DIONES VIA [4+2]-CYCLOADDITIONS: FROM PIONEERING STUDIES TO ASYMMETRIC ORGANOCATALYZED SYNTHESES 152
anti-Selective, Catalytic Asymmetric Vinylogous Mukaiyama Mannich Reactions of Pyrrole-Based Silyl Dienolates with N-Aryl Aldimines 151
Chemodivergent entry to enantioenriched (poly)phenol gamma-valerolactone metabolites and their delta-lactone analogues 149
Merging Vinylogy with Organocatalysis: Direct, Asymmetric Entry to Chiral Fused Uracil Derivatives 145
Aqueous and Solvent-Free Uncatalyzed Vinylogous Mukaiyama-Mannich Reaction of Pyrrole Dienoxy Silanes 144
Merging RGD/Sunitinib Chemotypes to Unique Hybrid Constructs is Useful to Impair Tumor Angiogenesis and Melanoma Growth 143
A novel, selective 111-In-labelled aminoproline-RGD-peptide for non-invasive tumor imaging: synthesis and preclinical evaluation 143
Synthesis of Novel c(AmpRGD)−Sunitinib Dual Conjugates as Molecular Tools Targeting the αvβ3 Integrin/VEGFR2 Couple and Impairing Tumor-Associated Angiogenesis 139
Discovery of Subnanomolar Arginine-Glycine-Aspartate-Based alphaVbeta3/alphaVbeta5 Integrin Binders Embedding 4-Aminoproline Residues 139
Towards New Small-Molecule Peptidomimetics as Selective alphaVbeta6 Integrin Ligands 139
Gold Nanoparticles Functionalized with RGD-Semipeptides: A Simple yet Highly Effective Targeting System for αVβ3 Integrins 139
111-InDOTA-aminoproline-RGD based cyclic semipeptides (cAmpRGD) for SPECT molecular imaging of melanoma 136
Synthesis and preclinical evaluation of a novel, selective 111-In-labelled aminoproline-RGD-peptide for non-invasive melanoma tumor imaging 136
Enantioselective Total Synthesis of (1R,3S,4R,5R)-1-Amino-4,5-dihydroxycyclopentane-1,3-dicarboxylic Acid. A Full-Aldol Access to Carbaketose Derivatives 135
Synthesis and Structure of a Novel Stereomutated Analogue of Oseltamivir Carboxylate 135
2-(tert-Butyldimethylsiloxy)thiophene: Application to Total Syntheses of Both Enantiomers of 2',3'-Dideoxy-4'-thiocytidine 135
Aqueous and Solvent-Free Uncatalyzed Three-Component Vinylogous Mukaiyama-Mannich Reactions of Pyrrole-Based Silyl Dienolates 135
On-Water Vinylogous Mukaiyama-Michael Addition of Heterocyclic 2-Silyloxydienes to 1,2-Diaza-1,3-dienes: One-Pot Three-Step Entry to Functionality-Rich Pyrroles 134
Pushing the Boundaries of Vinylogous Reactivity: Catalytic Enantioselective Mukaiyama Aldol Reactions of Highly Unsaturated 2-Silyloxyindoles 134
Facile Entry to 5,10,15,20-Tetra-C-glycosylporphyrins 133
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines 133
Total Synthesis of Both Enantiomers of trans-2,3-cis-3,4-Dihydroxyproline 133
cAmpRGD-functionalized Liposomes Loaded with a VEGFR Inhibitor for a Targeted and Combined Antiangiogenesis Activity 132
Towards new small-molecule peptidomimetics as selective αvβ6 integrin ligands 132
Stereoselective Aldol Reactions: Methodologies and Synthetic Applications 131
New 4-aminoproline-based small molecule cyclopeptidomimetics as potential modulators of α4β1 integrin 131
Furan-, Pyrrole- and Thiophene-Based Siloxydienes for Parallel and Combinatorial Syntheses of Sugar-Modified Nucleosides 129
AmpRGD/Sunitinib Dual Conjugates as Tumor Angiogenesis Modulators 128
Anti-αVβ3 integrin peptidomimetic-Sunitinib dual conjugates as therapeutic tool for the inhibition of integrin/growth factor cross-talk in human melanoma cells. 128
Dual Conjugates Targeting αVβ3/αVβ6 Integrins and Tyrosine Kinase Receptors as antifibrotic agents 128
Direct, asymmetric synthesis of carbocycle-fused uracils via [4+2] cycloadditions: a noncovalent organocatalysis approach 127
Novel AmpRGD-Sunitinib Dual Conjugates as Potential Inhibitors of Tumor Angiogenesis 126
Exploring the Remote Reactivity of p-Extended Carbonyl Compounds: The Vinylogous Alkylidene Malononitrile Activation Strategy 126
Ciclopeptidi a Base RGD Contenenti Unità Amminoproliniche: Una Nuova Classe di Potenti e Versatili Ligandi Integrinici 124
Exploring the Remote Reactivity of π-Extended Carbonyl Compounds: the Vinylogous Alkylidene Malononitrile Activation Strategy 123
3-(Alkoxycarbonyl-2-Alkyliden)-2-Oxindoles: a New, Enabling Progeny of Multidentate, Vinylogous Carbon Nucleophiles for the Direct, Enantioselective, Vinylogous Michael Addition to Nitroolefins 123
Covalent dual conjugates targeting V6 integrin and tyrosin kinases toward the treatment of idiopathic and pulmonary fibrosis 123
Identificazione Spettroscopica di Composti Organici - Prima Edizione 121
Diastereoselective Synthesis of 4,5'-Bis-proline Compounds via Reductive Dimerization of N-Acyloxyiminium Ions 120
A new method for the one-step synthesis of α,β-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds 120
Conceptually New Directed Aldol Condensation Using Aluminum Tris-(2,6-diphenylphenoxide) 119
The utility of furan-, pyrrole-, and thiophene-based 2-silyloxy dienes as demonstrated by modular synthesis of annonaceous acetogenin core units and their pyrrolidine and thiolane analogues 119
Novel Polymyxin-Inspired "Medium-Sized" Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interaction 118
Asymmetric Access to Functional, Structurally Diverse Molecules Exploiting Five-Membered Heterocyclic Silyloxy Dienes 118
The Principle of Vinylogy as Applied to Heterocyclic Donor Systems 118
Stereoselective synthesis of (poly)phenol human and microbial metabolites and related phase II conjugates 118
Synthetic and analytical strategies for the quantification of phenyl-γ-valerolactone conjugated metabolites in human urine 118
Una nuova Metodologia per la Sintesi di carbachetosi ed Analoghi: Acidi Glutammici Conformazionalmente Costretti 118
Stereoselective Aldol Reactions: Methodologies and Synthetic Applications 118
Discovery of subnanomolar arginine-glycine-aspartate-based αVβ3/αVβ5 integrin binders embedding 4-aminoproline residues 118
Nintedanib-Containing Dual Conjugates Targeting αVβ6 Integrin and Tyrosine Kinase Receptors as Potential Antifibrotic Agents 118
Total Syntheses of 2,4-Diamino-2,4-dideoxy-L-arabinose and 2,4-Diamino-2,4-dideoxy-L-ribose 117
Novel Carbasugar-Containing Cyclic RGD Peptides for Integrin Receptors Recognition 117
Catalytic, Asymmetric Hypervinylogous Mukaiyama Aldol Reactions of Extended Furan-Based Silyl Enolates 117
Organocatalytic Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Linear and Angular Polycycles 117
Novel AmpRGD/Sunitinib Dual Conjugates as Potential Modulators of Tumor Angiogenesis 117
Variable Strategy towards Carbasugars and Relatives. 6. Diastereoselective Synthesis of 2-Deoxy-2-amino-5a-carba-beta-L-mannopyranuronic Acid and 2-Deoxy-2-amino-5a-carba-beta-L-mannopyranose 116
Diastereo- and Enantioselective Catalytic Vinylogous Mukaiyama-Mannich Reactions of Pyrrole-Based Silyl Dienolates with Alkyl-Substituted Aldehydes 116
Total Synthesis of Lactacystin - An enantioselective Synthesis of (6R)-Lactacystin — Total Synthesis of (+)-Lactacystin, the First Non-Protein Neurotrophic Factor - Total Synthesis of (+)-Lactacystin from (R)-Glutamate 116
Catalytic, Enantioselective Vinylogous Mukaiyama Aldol Reaction of Furan-Based Dienoxy Silanes: A Chemodivergent Approach to γ-Valerolactone Flavan-3-ol Metabolites and δ-Lactone Analogues 116
Variable Strategy toward Carbasugars and Relatives. 1. Stereocontrolled Synthesis of Pseudo-beta-D-gulopyranose, Pseudo-beta-D-xylofuranose, (Pseudo-beta-D-gulopyranosyl)amine, and (Pseudo-beta-D-xylofuranosyl)amine 115
Gold Nanoparticles Functionalized with cAmpRGD-Peptidomimetics: a Simple yet Highly Effective Targeting System for alphaVbeta3 Integrins 115
Totale 18.474
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Categoria #
all - tutte 97.295
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 97.295
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.150 0 23 23 66 32 59 174 154 50 85 97 387
2022/20234.047 446 399 286 287 346 428 36 287 1.264 69 141 58
2023/20241.395 78 124 41 58 116 345 131 102 38 95 113 154
2024/20254.359 68 275 276 178 434 442 204 203 559 438 354 928
2025/202612.672 944 3.281 1.977 712 1.342 530 1.140 263 1.281 793 260 149
2026/2027633 289 344 0 0 0 0 0 0 0 0 0 0
Totale 29.603