IRIS
ZANARDI, Franca
 Distribuzione geografica
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Continente #
NA - Nord America 12.448
AS - Asia 8.277
EU - Europa 6.482
SA - Sud America 1.090
AF - Africa 381
Continente sconosciuto - Info sul continente non disponibili 10
OC - Oceania 5
AN - Antartide 1
Totale 28.694
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Nazione #
US - Stati Uniti d'America 12.173
SG - Singapore 2.869
CN - Cina 2.228
IT - Italia 1.323
VN - Vietnam 1.320
IE - Irlanda 994
SE - Svezia 919
FI - Finlandia 866
BR - Brasile 847
DE - Germania 748
HK - Hong Kong 664
UA - Ucraina 447
TR - Turchia 327
NL - Olanda 269
ZA - Sudafrica 255
FR - Francia 250
IN - India 234
GB - Regno Unito 167
CA - Canada 159
RU - Federazione Russa 139
BD - Bangladesh 123
AR - Argentina 93
ES - Italia 73
MX - Messico 67
IQ - Iraq 65
KR - Corea 60
JP - Giappone 57
BE - Belgio 52
EC - Ecuador 51
DK - Danimarca 48
PL - Polonia 42
AT - Austria 40
PH - Filippine 39
MA - Marocco 34
PK - Pakistan 33
ID - Indonesia 32
VE - Venezuela 27
IR - Iran 26
CO - Colombia 24
EG - Egitto 24
TH - Thailandia 24
CZ - Repubblica Ceca 21
UZ - Uzbekistan 19
RO - Romania 17
TW - Taiwan 17
JO - Giordania 16
CL - Cile 15
KE - Kenya 15
PY - Paraguay 14
LT - Lituania 13
MY - Malesia 12
PA - Panama 12
CI - Costa d'Avorio 11
IL - Israele 11
KZ - Kazakistan 11
NP - Nepal 11
SA - Arabia Saudita 10
TN - Tunisia 10
BH - Bahrain 9
DZ - Algeria 9
EU - Europa 9
JM - Giamaica 9
AE - Emirati Arabi Uniti 8
AZ - Azerbaigian 8
ET - Etiopia 8
LB - Libano 8
PE - Perù 8
SK - Slovacchia (Repubblica Slovacca) 8
BO - Bolivia 6
CH - Svizzera 6
CR - Costa Rica 6
OM - Oman 6
PS - Palestinian Territory 6
GT - Guatemala 5
RS - Serbia 5
AU - Australia 4
BG - Bulgaria 4
HN - Honduras 4
PT - Portogallo 4
TT - Trinidad e Tobago 4
UY - Uruguay 4
AL - Albania 3
AM - Armenia 3
AO - Angola 3
BY - Bielorussia 3
CY - Cipro 3
DO - Repubblica Dominicana 3
HR - Croazia 3
KW - Kuwait 3
MD - Moldavia 3
SN - Senegal 3
SY - Repubblica araba siriana 3
BB - Barbados 2
CG - Congo 2
GE - Georgia 2
GR - Grecia 2
HU - Ungheria 2
LK - Sri Lanka 2
LU - Lussemburgo 2
ME - Montenegro 2
Totale 28.664
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Città #
Dallas 3.703
Singapore 1.342
Ashburn 1.102
Chandler 1.015
Dublin 988
San Jose 892
Hong Kong 629
Beijing 611
Jacksonville 601
Santa Clara 545
Ho Chi Minh City 390
Parma 374
Ann Arbor 322
Hanoi 312
Dearborn 288
Izmir 271
Boardman 270
Johannesburg 239
Nanjing 220
Princeton 205
Lauterbourg 194
Los Angeles 173
Munich 171
San Mateo 143
New York 140
Helsinki 133
Shanghai 126
Wilmington 125
Hefei 107
Buffalo 85
Moscow 85
Toronto 84
Shenyang 77
Des Moines 75
Frankfurt am Main 75
São Paulo 74
Nanchang 70
Bremen 69
Pune 68
Milan 67
Bologna 65
Columbus 58
Seattle 55
Hebei 54
Da Nang 53
Jinan 53
Changsha 49
Vigevano 49
Woodbridge 48
Brussels 47
Tianjin 47
Haiphong 46
Council Bluffs 44
Seoul 44
Guangzhou 43
Kunming 43
Modena 41
Aarhus 40
Rio de Janeiro 36
Houston 35
Tokyo 35
Chennai 31
Chicago 30
Jiaxing 30
Vienna 30
Warsaw 30
Rome 28
Brooklyn 27
Fremont 27
Orem 27
Biên Hòa 26
Leawood 26
Atlanta 25
Montreal 24
Mumbai 24
The Dalles 24
Turku 24
Zhengzhou 24
Nuremberg 22
Reggio Emilia 22
Baghdad 21
Amsterdam 20
Ardea 20
Brescia 20
San Francisco 20
Belo Horizonte 19
Florence 19
London 19
Quito 19
Augusta 18
Boston 18
Guayaquil 18
Phoenix 18
Segrate 18
Tashkent 18
Jakarta 17
Norwalk 17
Piacenza 17
Redwood City 17
Stockholm 17
Totale 18.316
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Nome #
The 1,4- and 1,6-Addition of Vinylogous Donor Systems in on-Water and Organocatalyzed Reactions 1.641
Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung Cancer 631
Turning the Imidazole Core into Three‐Dimensional Ring Systems: Mild Organocatalytic Entry to Enantiopure 6,7‐Dihydrobenzimidazoles 629
The Chiral 5,6-Cyclohexane-fused Uracil Ring-System: a Molecular Platform with Promising Activity against SARS-CoV-2 599
Harnessing Vinylogy with Radicals: Photoinduced γ-Benzylation Reactions of 2-Silyloxyfurans 595
Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interface 570
Catalytic, Asymmetric Vinylogous Mukaiyama Aldol Reactions of Pyrrole- and Furan-Based Dienoxy Silanes: How the Diene Heteroatom Impacts Stereocontrol 228
Direct, Asymmetric Synthesis of Carbocycle-Fused Uracils via [4+2] Cycloadditions: a Noncovalent Organocatalysis Approach 228
Shifting Towards αVβ6 Integrin Ligands Using Novel Aminoproline-Based Cyclic Peptidomimetics 223
Grafting Aminocyclopentane Carboxylic Acids onto the RGD Tripeptide Sequence Generates Low Nanomolar alfaVbeta3/alfaVbeta5 Integrin Dual Binders 215
Integrin-targeted AmpRGD sunitinib liposomes as integrated antiangiogenic tools 211
(2S,4R)-4-fluoroglutamine is converted into (2S,4R)-4-fluoroglutamate by glutaminase activity and may be exploited as a PET tracer in glutamine-addicted cancers 211
[18F](2S,4R)-4-Fluoroglutamine as a New Positron Emission Tomography Tracer in Myeloma 206
Identificazione spettrometrica di composti organici 204
3-Alkylidene-2-oxindoles in Vinylogous Mukaiyama Mannich Reactions: Synthesis of Multifaceted Aminated Scaffolds 203
New Developments of the Principle of Vinylogy as Applied to π-Extended Enolate-Type Donor Systems 203
Cell-targeted c(AmpRGD)-sunitinib molecular conjugates impair tumor growth of melanoma 194
(E)-3-(Alkoxycarbonyl-2-Alkyliden)-2-Oxindoles: Multidentate Pronucleophiles for the Organocatalytic, Vinylogous Michael Addition to Nitroolefins 187
Unlocking Access to Enantiopure Fused Uracils by Chemodivergent [4+2] Cross‐Cycloadditions: DFT‐Supported Homo‐Synergistic Organocatalytic Approach 184
Advances in Exploring Heterocyclic Dienoxysilane Nucleophiles in Asymmetric Synthesis 176
Mechanistic Insights into the Stepwise (4+2) Cycloaddition toward Chiral Fused Uracil Derivatives 175
Acetaldehyde Silyl Enol Ethers in Enantioselective Mukaiyama Aldol Reactions: Enzyme-Like Organocatalysis in Action 173
Ciclopeptidi Ibridi Contenenti Amminoacidi Cicloalcanici, e Loro Preparazione ed Uso 173
AmpRGD-Functionalized Liposomes: From Targeted Delivery Vehicles to Integrated Targeted Antiangiogenic Tools 172
3‑Alkenyl-2-silyloxyindoles in Vinylogous Mannich Reactions: Synthesis of Aminated Indole-Based Scaffolds and Products. 164
3-Alkenyl-2-silyloxyindoles: An Enabling, Yet Understated Progeny of Vinylogous Carbon Nucleophiles 163
Novel RGD-based integrin targeted agents for selective in vivo cancer imaging 163
A ONE-POT ENTRY TO A NOVEL 3-H-BENZO[D]PYRAZOLO[1,5-B]ISOTHIAZOLE RING SYSTEM. 161
A new stereoselective entry to novel, chiral fused-carbocycle uracils 161
Organocatalytic, Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Cyclohexadiene-Embedding Linear and Angular Polycycles 158
A New, Enantioselective Entry to Cycloheptane Amino Acid Polyols 157
Direct, asymmetric synthesis of carbocycle-fused uracils via [4+2] cycloadditions: a noncovalent organocatalysis approach 157
RGD Peptide-Drug Conjugates as Effective Dual Targeting Platforms: Recent Advances 156
4-Aminoproline-Based Arginine-Glycine-Aspartate Integrin Binders with Exposed Ligation Points: Practical in-Solution Synthesis, Conjugation and Binding Affinity Evaluation 156
Towards new small-molecule peptidomimetics as potent and selective αvβ6 integrin ligands 154
An expeditious procedure for catalytic enantioselective three-component vinylogous Mukaiyama Mannich reactions 151
Exploiting the Distal Reactivity of Indolyl- methylenemalononitriles: an Asymmetric Organocatalyzed [4+2] Cycloaddition with Enals Enables the Assembly of Elusive Dihydrocarbazoles 151
Nintedanib-αVβ3 Integrin Ligand Dual-Targeting Conjugates towards Precision Treatment of Melanoma 150
anti-Selective, Catalytic Asymmetric Vinylogous Mukaiyama Mannich Reactions of Pyrrole-Based Silyl Dienolates with N-Aryl Aldimines 149
ACCESSING CHIRAL DIHYDRO- AND TETRAHYDROQUINAZOLINE-2,4-DIONES VIA [4+2]-CYCLOADDITIONS: FROM PIONEERING STUDIES TO ASYMMETRIC ORGANOCATALYZED SYNTHESES 148
Chemodivergent entry to enantioenriched (poly)phenol gamma-valerolactone metabolites and their delta-lactone analogues 146
Merging Vinylogy with Organocatalysis: Direct, Asymmetric Entry to Chiral Fused Uracil Derivatives 144
Aqueous and Solvent-Free Uncatalyzed Vinylogous Mukaiyama-Mannich Reaction of Pyrrole Dienoxy Silanes 143
A novel, selective 111-In-labelled aminoproline-RGD-peptide for non-invasive tumor imaging: synthesis and preclinical evaluation 140
Discovery of Subnanomolar Arginine-Glycine-Aspartate-Based alphaVbeta3/alphaVbeta5 Integrin Binders Embedding 4-Aminoproline Residues 138
Towards New Small-Molecule Peptidomimetics as Selective alphaVbeta6 Integrin Ligands 138
Merging RGD/Sunitinib Chemotypes to Unique Hybrid Constructs is Useful to Impair Tumor Angiogenesis and Melanoma Growth 137
Gold Nanoparticles Functionalized with RGD-Semipeptides: A Simple yet Highly Effective Targeting System for αVβ3 Integrins 137
Synthesis of Novel c(AmpRGD)−Sunitinib Dual Conjugates as Molecular Tools Targeting the αvβ3 Integrin/VEGFR2 Couple and Impairing Tumor-Associated Angiogenesis 136
111-InDOTA-aminoproline-RGD based cyclic semipeptides (cAmpRGD) for SPECT molecular imaging of melanoma 134
Synthesis and Structure of a Novel Stereomutated Analogue of Oseltamivir Carboxylate 134
Aqueous and Solvent-Free Uncatalyzed Three-Component Vinylogous Mukaiyama-Mannich Reactions of Pyrrole-Based Silyl Dienolates 134
On-Water Vinylogous Mukaiyama-Michael Addition of Heterocyclic 2-Silyloxydienes to 1,2-Diaza-1,3-dienes: One-Pot Three-Step Entry to Functionality-Rich Pyrroles 132
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines 132
2-(tert-Butyldimethylsiloxy)thiophene: Application to Total Syntheses of Both Enantiomers of 2',3'-Dideoxy-4'-thiocytidine 132
Synthesis and preclinical evaluation of a novel, selective 111-In-labelled aminoproline-RGD-peptide for non-invasive melanoma tumor imaging 132
Enantioselective Total Synthesis of (1R,3S,4R,5R)-1-Amino-4,5-dihydroxycyclopentane-1,3-dicarboxylic Acid. A Full-Aldol Access to Carbaketose Derivatives 131
cAmpRGD-functionalized Liposomes Loaded with a VEGFR Inhibitor for a Targeted and Combined Antiangiogenesis Activity 131
Towards new small-molecule peptidomimetics as selective αvβ6 integrin ligands 131
Pushing the Boundaries of Vinylogous Reactivity: Catalytic Enantioselective Mukaiyama Aldol Reactions of Highly Unsaturated 2-Silyloxyindoles 130
New 4-aminoproline-based small molecule cyclopeptidomimetics as potential modulators of α4β1 integrin 130
Stereoselective Aldol Reactions: Methodologies and Synthetic Applications 129
Facile Entry to 5,10,15,20-Tetra-C-glycosylporphyrins 128
Total Synthesis of Both Enantiomers of trans-2,3-cis-3,4-Dihydroxyproline 128
Furan-, Pyrrole- and Thiophene-Based Siloxydienes for Parallel and Combinatorial Syntheses of Sugar-Modified Nucleosides 127
AmpRGD/Sunitinib Dual Conjugates as Tumor Angiogenesis Modulators 127
Anti-αVβ3 integrin peptidomimetic-Sunitinib dual conjugates as therapeutic tool for the inhibition of integrin/growth factor cross-talk in human melanoma cells. 127
Direct, asymmetric synthesis of carbocycle-fused uracils via [4+2] cycloadditions: a noncovalent organocatalysis approach 126
Dual Conjugates Targeting αVβ3/αVβ6 Integrins and Tyrosine Kinase Receptors as antifibrotic agents 126
Novel AmpRGD-Sunitinib Dual Conjugates as Potential Inhibitors of Tumor Angiogenesis 125
Exploring the Remote Reactivity of p-Extended Carbonyl Compounds: The Vinylogous Alkylidene Malononitrile Activation Strategy 125
Ciclopeptidi a Base RGD Contenenti Unità Amminoproliniche: Una Nuova Classe di Potenti e Versatili Ligandi Integrinici 122
Covalent dual conjugates targeting V6 integrin and tyrosin kinases toward the treatment of idiopathic and pulmonary fibrosis 121
Identificazione Spettroscopica di Composti Organici - Prima Edizione 120
Exploring the Remote Reactivity of π-Extended Carbonyl Compounds: the Vinylogous Alkylidene Malononitrile Activation Strategy 120
3-(Alkoxycarbonyl-2-Alkyliden)-2-Oxindoles: a New, Enabling Progeny of Multidentate, Vinylogous Carbon Nucleophiles for the Direct, Enantioselective, Vinylogous Michael Addition to Nitroolefins 120
Diastereoselective Synthesis of 4,5'-Bis-proline Compounds via Reductive Dimerization of N-Acyloxyiminium Ions 119
Synthetic and analytical strategies for the quantification of phenyl-γ-valerolactone conjugated metabolites in human urine 118
Conceptually New Directed Aldol Condensation Using Aluminum Tris-(2,6-diphenylphenoxide) 117
A new method for the one-step synthesis of α,β-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds 117
Discovery of subnanomolar arginine-glycine-aspartate-based αVβ3/αVβ5 integrin binders embedding 4-aminoproline residues 117
Novel Polymyxin-Inspired "Medium-Sized" Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interaction 116
Novel Carbasugar-Containing Cyclic RGD Peptides for Integrin Receptors Recognition 116
Catalytic, Asymmetric Hypervinylogous Mukaiyama Aldol Reactions of Extended Furan-Based Silyl Enolates 116
The Principle of Vinylogy as Applied to Heterocyclic Donor Systems 116
Stereoselective synthesis of (poly)phenol human and microbial metabolites and related phase II conjugates 116
Stereoselective Aldol Reactions: Methodologies and Synthetic Applications 116
Novel AmpRGD/Sunitinib Dual Conjugates as Potential Modulators of Tumor Angiogenesis 116
The utility of furan-, pyrrole-, and thiophene-based 2-silyloxy dienes as demonstrated by modular synthesis of annonaceous acetogenin core units and their pyrrolidine and thiolane analogues 116
Variable Strategy towards Carbasugars and Relatives. 6. Diastereoselective Synthesis of 2-Deoxy-2-amino-5a-carba-beta-L-mannopyranuronic Acid and 2-Deoxy-2-amino-5a-carba-beta-L-mannopyranose 115
Diastereo- and Enantioselective Catalytic Vinylogous Mukaiyama-Mannich Reactions of Pyrrole-Based Silyl Dienolates with Alkyl-Substituted Aldehydes 115
Organocatalytic Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Linear and Angular Polycycles 115
Nintedanib-Containing Dual Conjugates Targeting αVβ6 Integrin and Tyrosine Kinase Receptors as Potential Antifibrotic Agents 115
Una nuova Metodologia per la Sintesi di carbachetosi ed Analoghi: Acidi Glutammici Conformazionalmente Costretti 114
Total Synthesis of Lactacystin - An enantioselective Synthesis of (6R)-Lactacystin — Total Synthesis of (+)-Lactacystin, the First Non-Protein Neurotrophic Factor - Total Synthesis of (+)-Lactacystin from (R)-Glutamate 114
Variable Strategy toward Carbasugars and Relatives. 1. Stereocontrolled Synthesis of Pseudo-beta-D-gulopyranose, Pseudo-beta-D-xylofuranose, (Pseudo-beta-D-gulopyranosyl)amine, and (Pseudo-beta-D-xylofuranosyl)amine 113
Asymmetric Access to Functional, Structurally Diverse Molecules Exploiting Five-Membered Heterocyclic Silyloxy Dienes 113
Diastereoselective Synthesis of alpha-C-Arabinofuranosyl Glycine 113
Total Syntheses of 2,4-Diamino-2,4-dideoxy-L-arabinose and 2,4-Diamino-2,4-dideoxy-L-ribose 113
Approccio Modulare per la Construzione di Insiemi di Acetogenine delle Annonaceae e loro Varianti Strutturali 113
Totale 18.212
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Categoria #
all - tutte 92.722
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 92.722
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202155 0 0 0 0 0 0 0 0 0 0 0 55
2021/20221.185 35 23 23 66 32 59 174 154 50 85 97 387
2022/20234.047 446 399 286 287 346 428 36 287 1.264 69 141 58
2023/20241.395 78 124 41 58 116 345 131 102 38 95 113 154
2024/20254.359 68 275 276 178 434 442 204 203 559 438 354 928
2025/202612.642 944 3.281 1.977 712 1.342 530 1.140 263 1.281 793 260 119
Totale 28.940