IRIS
ZANARDI, Franca
 Distribuzione geografica
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Continente #
NA - Nord America 14.423
AS - Asia 8.387
EU - Europa 6.735
SA - Sud America 1.163
AF - Africa 390
Continente sconosciuto - Info sul continente non disponibili 272
OC - Oceania 5
AN - Antartide 1
Totale 31.376
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Nazione #
US - Stati Uniti d'America 14.047
SG - Singapore 2.883
CN - Cina 2.250
IT - Italia 1.451
VN - Vietnam 1.325
IE - Irlanda 995
SE - Svezia 965
BR - Brasile 877
FI - Finlandia 866
DE - Germania 758
HK - Hong Kong 675
UA - Ucraina 449
TR - Turchia 329
NL - Olanda 270
FR - Francia 258
ZA - Sudafrica 255
IN - India 239
CA - Canada 193
GB - Regno Unito 192
RU - Federazione Russa 140
BD - Bangladesh 131
AR - Argentina 98
MX - Messico 79
ES - Italia 76
IQ - Iraq 65
EC - Ecuador 61
JP - Giappone 60
KR - Corea 60
BE - Belgio 53
DK - Danimarca 50
PL - Polonia 44
AT - Austria 43
CO - Colombia 43
PH - Filippine 42
ID - Indonesia 37
PK - Pakistan 35
MA - Marocco 34
VE - Venezuela 34
TH - Thailandia 29
IR - Iran 26
EG - Egitto 24
CZ - Repubblica Ceca 21
MY - Malesia 19
TW - Taiwan 19
UZ - Uzbekistan 19
CR - Costa Rica 18
JM - Giamaica 18
IL - Israele 17
KE - Kenya 17
RO - Romania 17
CL - Cile 16
JO - Giordania 16
KZ - Kazakistan 14
LT - Lituania 14
PY - Paraguay 14
CH - Svizzera 12
PA - Panama 12
SA - Arabia Saudita 12
CI - Costa d'Avorio 11
GT - Guatemala 11
NP - Nepal 11
BH - Bahrain 10
GR - Grecia 10
TN - Tunisia 10
TT - Trinidad e Tobago 10
AE - Emirati Arabi Uniti 9
DZ - Algeria 9
EU - Europa 9
HN - Honduras 9
AZ - Azerbaigian 8
ET - Etiopia 8
LB - Libano 8
PE - Perù 8
SK - Slovacchia (Repubblica Slovacca) 8
SV - El Salvador 8
BO - Bolivia 6
OM - Oman 6
PS - Palestinian Territory 6
AL - Albania 5
MD - Moldavia 5
NI - Nicaragua 5
RS - Serbia 5
SC - Seychelles 5
UY - Uruguay 5
AU - Australia 4
BG - Bulgaria 4
DO - Repubblica Dominicana 4
KW - Kuwait 4
PT - Portogallo 4
AM - Armenia 3
AO - Angola 3
BY - Bielorussia 3
CG - Congo 3
CW - ???statistics.table.value.countryCode.CW??? 3
CY - Cipro 3
HR - Croazia 3
QA - Qatar 3
SN - Senegal 3
SY - Repubblica araba siriana 3
BB - Barbados 2
Totale 31.073
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Città #
Dallas 3.715
Ashburn 1.420
Singapore 1.350
Chandler 1.015
Dublin 989
San Jose 978
Santa Clara 718
Hong Kong 636
Beijing 614
Jacksonville 603
Council Bluffs 394
Ho Chi Minh City 393
Parma 393
Ann Arbor 323
Hanoi 313
Washington 307
Dearborn 288
Boardman 271
Izmir 271
Johannesburg 239
Nanjing 220
Princeton 205
Lauterbourg 194
Los Angeles 183
Munich 173
New York 146
San Mateo 143
Helsinki 133
Shanghai 130
Wilmington 127
Hefei 107
Buffalo 95
Milan 88
São Paulo 86
Moscow 85
Toronto 85
Des Moines 77
Shenyang 77
Frankfurt am Main 75
Bologna 71
Nanchang 70
Bremen 69
Pune 68
Columbus 59
Seattle 58
Hebei 54
Da Nang 53
Jinan 53
Woodbridge 50
Changsha 49
Vigevano 49
Brussels 47
Tianjin 47
Haiphong 46
Seoul 44
Guangzhou 43
Kunming 43
Modena 42
Aarhus 40
Houston 37
Rio de Janeiro 37
Rome 37
Chicago 36
Tokyo 35
Atlanta 34
Phoenix 33
Montreal 32
Brooklyn 31
Chennai 31
Jiaxing 30
Vienna 30
Warsaw 30
Fremont 27
Orem 27
Biên Hòa 26
Leawood 26
Mumbai 24
San Francisco 24
The Dalles 24
Turku 24
Zhengzhou 24
Quito 23
Florence 22
Nuremberg 22
Reggio Emilia 22
Baghdad 21
Amsterdam 20
Ardea 20
Brescia 20
Denver 20
Guayaquil 20
Belo Horizonte 19
London 19
Augusta 18
Boston 18
Segrate 18
Tashkent 18
Jakarta 17
Mexico City 17
Norwalk 17
Totale 19.744
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Nome #
The 1,4- and 1,6-Addition of Vinylogous Donor Systems in on-Water and Organocatalyzed Reactions 1.675
Turning the Imidazole Core into Three‐Dimensional Ring Systems: Mild Organocatalytic Entry to Enantiopure 6,7‐Dihydrobenzimidazoles 643
Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung Cancer 638
The Chiral 5,6-Cyclohexane-fused Uracil Ring-System: a Molecular Platform with Promising Activity against SARS-CoV-2 622
Harnessing Vinylogy with Radicals: Photoinduced γ-Benzylation Reactions of 2-Silyloxyfurans 615
Novel Polymyxin-Inspired Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interface 585
Direct, Asymmetric Synthesis of Carbocycle-Fused Uracils via [4+2] Cycloadditions: a Noncovalent Organocatalysis Approach 241
Catalytic, Asymmetric Vinylogous Mukaiyama Aldol Reactions of Pyrrole- and Furan-Based Dienoxy Silanes: How the Diene Heteroatom Impacts Stereocontrol 237
Shifting Towards αVβ6 Integrin Ligands Using Novel Aminoproline-Based Cyclic Peptidomimetics 233
Grafting Aminocyclopentane Carboxylic Acids onto the RGD Tripeptide Sequence Generates Low Nanomolar alfaVbeta3/alfaVbeta5 Integrin Dual Binders 226
Identificazione spettrometrica di composti organici 225
Integrin-targeted AmpRGD sunitinib liposomes as integrated antiangiogenic tools 221
New Developments of the Principle of Vinylogy as Applied to π-Extended Enolate-Type Donor Systems 218
(2S,4R)-4-fluoroglutamine is converted into (2S,4R)-4-fluoroglutamate by glutaminase activity and may be exploited as a PET tracer in glutamine-addicted cancers 218
3-Alkylidene-2-oxindoles in Vinylogous Mukaiyama Mannich Reactions: Synthesis of Multifaceted Aminated Scaffolds 216
[18F](2S,4R)-4-Fluoroglutamine as a New Positron Emission Tomography Tracer in Myeloma 216
(E)-3-(Alkoxycarbonyl-2-Alkyliden)-2-Oxindoles: Multidentate Pronucleophiles for the Organocatalytic, Vinylogous Michael Addition to Nitroolefins 203
Cell-targeted c(AmpRGD)-sunitinib molecular conjugates impair tumor growth of melanoma 203
Advances in Exploring Heterocyclic Dienoxysilane Nucleophiles in Asymmetric Synthesis 193
Mechanistic Insights into the Stepwise (4+2) Cycloaddition toward Chiral Fused Uracil Derivatives 189
Unlocking Access to Enantiopure Fused Uracils by Chemodivergent [4+2] Cross‐Cycloadditions: DFT‐Supported Homo‐Synergistic Organocatalytic Approach 189
AmpRGD-Functionalized Liposomes: From Targeted Delivery Vehicles to Integrated Targeted Antiangiogenic Tools 186
Acetaldehyde Silyl Enol Ethers in Enantioselective Mukaiyama Aldol Reactions: Enzyme-Like Organocatalysis in Action 184
Ciclopeptidi Ibridi Contenenti Amminoacidi Cicloalcanici, e Loro Preparazione ed Uso 184
3‑Alkenyl-2-silyloxyindoles in Vinylogous Mannich Reactions: Synthesis of Aminated Indole-Based Scaffolds and Products. 177
3-Alkenyl-2-silyloxyindoles: An Enabling, Yet Understated Progeny of Vinylogous Carbon Nucleophiles 175
RGD Peptide-Drug Conjugates as Effective Dual Targeting Platforms: Recent Advances 175
A new stereoselective entry to novel, chiral fused-carbocycle uracils 175
ACCESSING CHIRAL DIHYDRO- AND TETRAHYDROQUINAZOLINE-2,4-DIONES VIA [4+2]-CYCLOADDITIONS: FROM PIONEERING STUDIES TO ASYMMETRIC ORGANOCATALYZED SYNTHESES 171
A ONE-POT ENTRY TO A NOVEL 3-H-BENZO[D]PYRAZOLO[1,5-B]ISOTHIAZOLE RING SYSTEM. 171
Organocatalytic, Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Cyclohexadiene-Embedding Linear and Angular Polycycles 171
Novel RGD-based integrin targeted agents for selective in vivo cancer imaging 169
4-Aminoproline-Based Arginine-Glycine-Aspartate Integrin Binders with Exposed Ligation Points: Practical in-Solution Synthesis, Conjugation and Binding Affinity Evaluation 169
An expeditious procedure for catalytic enantioselective three-component vinylogous Mukaiyama Mannich reactions 167
A New, Enantioselective Entry to Cycloheptane Amino Acid Polyols 166
Direct, asymmetric synthesis of carbocycle-fused uracils via [4+2] cycloadditions: a noncovalent organocatalysis approach 165
Nintedanib-αVβ3 Integrin Ligand Dual-Targeting Conjugates towards Precision Treatment of Melanoma 164
Chemodivergent entry to enantioenriched (poly)phenol gamma-valerolactone metabolites and their delta-lactone analogues 162
Towards new small-molecule peptidomimetics as potent and selective αvβ6 integrin ligands 162
Merging RGD/Sunitinib Chemotypes to Unique Hybrid Constructs is Useful to Impair Tumor Angiogenesis and Melanoma Growth 158
anti-Selective, Catalytic Asymmetric Vinylogous Mukaiyama Mannich Reactions of Pyrrole-Based Silyl Dienolates with N-Aryl Aldimines 157
Exploiting the Distal Reactivity of Indolyl- methylenemalononitriles: an Asymmetric Organocatalyzed [4+2] Cycloaddition with Enals Enables the Assembly of Elusive Dihydrocarbazoles 157
A novel, selective 111-In-labelled aminoproline-RGD-peptide for non-invasive tumor imaging: synthesis and preclinical evaluation 157
Enantioselective Total Synthesis of (1R,3S,4R,5R)-1-Amino-4,5-dihydroxycyclopentane-1,3-dicarboxylic Acid. A Full-Aldol Access to Carbaketose Derivatives 151
Synthesis of Novel c(AmpRGD)−Sunitinib Dual Conjugates as Molecular Tools Targeting the αvβ3 Integrin/VEGFR2 Couple and Impairing Tumor-Associated Angiogenesis 151
Synthesis and preclinical evaluation of a novel, selective 111-In-labelled aminoproline-RGD-peptide for non-invasive melanoma tumor imaging 149
Merging Vinylogy with Organocatalysis: Direct, Asymmetric Entry to Chiral Fused Uracil Derivatives 149
Aqueous and Solvent-Free Uncatalyzed Vinylogous Mukaiyama-Mannich Reaction of Pyrrole Dienoxy Silanes 148
Gold Nanoparticles Functionalized with RGD-Semipeptides: A Simple yet Highly Effective Targeting System for αVβ3 Integrins 148
2-(tert-Butyldimethylsiloxy)thiophene: Application to Total Syntheses of Both Enantiomers of 2',3'-Dideoxy-4'-thiocytidine 146
Discovery of Subnanomolar Arginine-Glycine-Aspartate-Based alphaVbeta3/alphaVbeta5 Integrin Binders Embedding 4-Aminoproline Residues 146
cAmpRGD-functionalized Liposomes Loaded with a VEGFR Inhibitor for a Targeted and Combined Antiangiogenesis Activity 144
On-Water Vinylogous Mukaiyama-Michael Addition of Heterocyclic 2-Silyloxydienes to 1,2-Diaza-1,3-dienes: One-Pot Three-Step Entry to Functionality-Rich Pyrroles 142
111-InDOTA-aminoproline-RGD based cyclic semipeptides (cAmpRGD) for SPECT molecular imaging of melanoma 141
Pushing the Boundaries of Vinylogous Reactivity: Catalytic Enantioselective Mukaiyama Aldol Reactions of Highly Unsaturated 2-Silyloxyindoles 141
Towards New Small-Molecule Peptidomimetics as Selective alphaVbeta6 Integrin Ligands 141
Synthesis and Structure of a Novel Stereomutated Analogue of Oseltamivir Carboxylate 140
Aqueous and Solvent-Free Uncatalyzed Three-Component Vinylogous Mukaiyama-Mannich Reactions of Pyrrole-Based Silyl Dienolates 140
Facile Entry to 5,10,15,20-Tetra-C-glycosylporphyrins 139
Total Synthesis of Both Enantiomers of trans-2,3-cis-3,4-Dihydroxyproline 139
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines 138
Novel AmpRGD-Sunitinib Dual Conjugates as Potential Inhibitors of Tumor Angiogenesis 138
Exploring the Remote Reactivity of p-Extended Carbonyl Compounds: The Vinylogous Alkylidene Malononitrile Activation Strategy 138
New 4-aminoproline-based small molecule cyclopeptidomimetics as potential modulators of α4β1 integrin 138
The utility of furan-, pyrrole-, and thiophene-based 2-silyloxy dienes as demonstrated by modular synthesis of annonaceous acetogenin core units and their pyrrolidine and thiolane analogues 136
Furan-, Pyrrole- and Thiophene-Based Siloxydienes for Parallel and Combinatorial Syntheses of Sugar-Modified Nucleosides 135
Stereoselective Aldol Reactions: Methodologies and Synthetic Applications 134
Towards new small-molecule peptidomimetics as selective αvβ6 integrin ligands 134
AmpRGD/Sunitinib Dual Conjugates as Tumor Angiogenesis Modulators 132
Anti-αVβ3 integrin peptidomimetic-Sunitinib dual conjugates as therapeutic tool for the inhibition of integrin/growth factor cross-talk in human melanoma cells. 132
Dual Conjugates Targeting αVβ3/αVβ6 Integrins and Tyrosine Kinase Receptors as antifibrotic agents 131
Novel cRGD-Anchoring Liposomes: Enhancement of the Uptake and Cytotoxic Activity of Doxorubicin in Cancer Cells 130
Exploring the Remote Reactivity of π-Extended Carbonyl Compounds: the Vinylogous Alkylidene Malononitrile Activation Strategy 130
Novel AmpRGD/Sunitinib Dual Conjugates as Potential Modulators of Tumor Angiogenesis 130
Direct, asymmetric synthesis of carbocycle-fused uracils via [4+2] cycloadditions: a noncovalent organocatalysis approach 130
3-(Alkoxycarbonyl-2-Alkyliden)-2-Oxindoles: a New, Enabling Progeny of Multidentate, Vinylogous Carbon Nucleophiles for the Direct, Enantioselective, Vinylogous Michael Addition to Nitroolefins 128
Variable Strategy towards Carbasugars and Relatives. 6. Diastereoselective Synthesis of 2-Deoxy-2-amino-5a-carba-beta-L-mannopyranuronic Acid and 2-Deoxy-2-amino-5a-carba-beta-L-mannopyranose 127
A new method for the one-step synthesis of α,β-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds 127
Catalytic, Enantioselective Vinylogous Mukaiyama Aldol Reaction of Furan-Based Dienoxy Silanes: A Chemodivergent Approach to γ-Valerolactone Flavan-3-ol Metabolites and δ-Lactone Analogues 127
Conceptually New Directed Aldol Condensation Using Aluminum Tris-(2,6-diphenylphenoxide) 126
Diastereoselective Synthesis of 4,5'-Bis-proline Compounds via Reductive Dimerization of N-Acyloxyiminium Ions 126
Ciclopeptidi a Base RGD Contenenti Unità Amminoproliniche: Una Nuova Classe di Potenti e Versatili Ligandi Integrinici 126
Stereoselective synthesis of (poly)phenol human and microbial metabolites and related phase II conjugates 126
Gold Nanoparticles Functionalized with cAmpRGD-Peptidomimetics: a Simple yet Highly Effective Targeting System for alphaVbeta3 Integrins 126
Covalent dual conjugates targeting V6 integrin and tyrosin kinases toward the treatment of idiopathic and pulmonary fibrosis 126
Synthetic and analytical strategies for the quantification of phenyl-γ-valerolactone conjugated metabolites in human urine 125
Total Synthesis of Lactacystin - An enantioselective Synthesis of (6R)-Lactacystin — Total Synthesis of (+)-Lactacystin, the First Non-Protein Neurotrophic Factor - Total Synthesis of (+)-Lactacystin from (R)-Glutamate 125
Diastereoselective Synthesis of a Novel Lactam Peptidomimetic Exploiting Vinylogous Mannich Addition of 2-Silyloxyfuran Reagents 124
Variable Strategy toward Carbasugars and Relatives. 1. Stereocontrolled Synthesis of Pseudo-beta-D-gulopyranose, Pseudo-beta-D-xylofuranose, (Pseudo-beta-D-gulopyranosyl)amine, and (Pseudo-beta-D-xylofuranosyl)amine 124
Total Syntheses of 2,4-Diamino-2,4-dideoxy-L-arabinose and 2,4-Diamino-2,4-dideoxy-L-ribose 124
Identificazione Spettroscopica di Composti Organici - Prima Edizione 124
The Principle of Vinylogy as Applied to Heterocyclic Donor Systems 124
Discovery of subnanomolar arginine-glycine-aspartate-based αVβ3/αVβ5 integrin binders embedding 4-aminoproline residues 124
Nintedanib-Containing Dual Conjugates Targeting αVβ6 Integrin and Tyrosine Kinase Receptors as Potential Antifibrotic Agents 124
Asymmetric Access to Functional, Structurally Diverse Molecules Exploiting Five-Membered Heterocyclic Silyloxy Dienes 123
Diastereoselective Synthesis of alpha-C-Arabinofuranosyl Glycine 123
Photoinduced, Chemoselective γ-Alkylation of 2-Silyloxyfurans with α-Bromoketones: A Rapid Entry to Chiral ε-Keto-γ-Butenolides 122
Antifibrotic Efficacy of a Nintedanib-Peptide Conjugate and Diagnostic Potential of a Fluorescent Companion Probe Targeting αVβ6 Integrin in Idiopathic Pulmonary Fibrosis 122
Organocatalytic Asymmetric Eliminative [4+2] Cycloaddition of Allylidene Malononitriles with Enals: Rapid Entry to Linear and Angular Polycycles 122
Novel Polymyxin-Inspired "Medium-Sized" Peptidomimetics Targeting the SARS-CoV-2 Spike:hACE2 Interaction 121
Totale 19.305
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Categoria #
all - tutte 103.624
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 103.624
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.104 0 0 0 66 32 59 174 154 50 85 97 387
2022/20234.047 446 399 286 287 346 428 36 287 1.264 69 141 58
2023/20241.395 78 124 41 58 116 345 131 102 38 95 113 154
2024/20254.359 68 275 276 178 434 442 204 203 559 438 354 928
2025/202612.672 944 3.281 1.977 712 1.342 530 1.140 263 1.281 793 260 149
2026/20272.406 289 542 512 1.063 0 0 0 0 0 0 0 0
Totale 31.376