Vinylogy and the reactions inspired by this principle occupy a rewarding position in the arsenal of chemical transformations. This review celebrates this principle, as applied to three enabling carbon−carbon bond formations, the aldol, Mannich and Michael reactions. Highlighted are those reactions involving heterocyclic vinylogous nucleophilic or pro-nucleophilic candidates, through which myriad of multifunctional molecular frameworks and targets could be synthesized. In this review, we mainly discuss investigations focusing on furan- and pyrrole-based donors, which appeared in the literature during the 2010−2012 triennium.
The Principle of Vinylogy as Applied to Heterocyclic Donor Systems / Zanardi, Franca; G., Rassu; Battistini, Lucia; Curti, Claudio; Sartori, Andrea; Casiraghi, Giovanni. - In: TARGETS IN HETEROCYCLIC SYSTEMS: CHEMISTRY AND PROPERTIES. - ISSN 1724-9449. - STAMPA. - 16:(2012), pp. 56-89.
The Principle of Vinylogy as Applied to Heterocyclic Donor Systems
ZANARDI, Franca;BATTISTINI, Lucia;CURTI, Claudio;SARTORI, Andrea;CASIRAGHI, Giovanni
2012-01-01
Abstract
Vinylogy and the reactions inspired by this principle occupy a rewarding position in the arsenal of chemical transformations. This review celebrates this principle, as applied to three enabling carbon−carbon bond formations, the aldol, Mannich and Michael reactions. Highlighted are those reactions involving heterocyclic vinylogous nucleophilic or pro-nucleophilic candidates, through which myriad of multifunctional molecular frameworks and targets could be synthesized. In this review, we mainly discuss investigations focusing on furan- and pyrrole-based donors, which appeared in the literature during the 2010−2012 triennium.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
