Mycotoxins are secondary metabolites produced by pathogenic fungi in crops worldwide. These compounds can undergo modification in plants, leading to the formation of a large number of possible modified forms, whose toxicological relevance and occurrence in food and feed is still largely unexplored. The analysis of modified mycotoxins by liquid chromatography-mass spectrometry remains a challenge because of their chemical diversity, the large number of isomeric forms, and the lack of analytical standards. Here, the potential benefits of high-resolution and ion mobility mass spectrometry as a tool for separation and structure confirmation of modified mycotoxins have been investigated/reviewed.

Recent advances and future challenges in modified mycotoxin analysis: Why HRMS has become a key instrument in food contaminant research / Righetti, Laura; Paglia, Giuseppe; Galaverna, Gianni; Dall'Asta, Chiara. - In: TOXINS. - ISSN 2072-6651. - 8:12(2016), p. 361. [10.3390/toxins8120361]

Recent advances and future challenges in modified mycotoxin analysis: Why HRMS has become a key instrument in food contaminant research

Righetti, Laura;Galaverna, Gianni;Dall'asta, Chiara
2016

Abstract

Mycotoxins are secondary metabolites produced by pathogenic fungi in crops worldwide. These compounds can undergo modification in plants, leading to the formation of a large number of possible modified forms, whose toxicological relevance and occurrence in food and feed is still largely unexplored. The analysis of modified mycotoxins by liquid chromatography-mass spectrometry remains a challenge because of their chemical diversity, the large number of isomeric forms, and the lack of analytical standards. Here, the potential benefits of high-resolution and ion mobility mass spectrometry as a tool for separation and structure confirmation of modified mycotoxins have been investigated/reviewed.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2835541
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