A fast, versatile and practical microwave-assisted multicomponent protocol for the synthesis of substituted benzofuran-2-carboxamides has been developed. The present method proved to be effective on a series of commercially available amines, 2′-hydroxyacetophenones, aldehydes, and benzonitriles and could be exploited in drug-discovery campaigns for the rapid identification of biologically active hit compounds.
A microwave-assisted multicomponent protocol for the synthesis of benzofuran-2-carboxamides / Vincetti, Paolo; Brianza, Anna; Scalacci, Nicolò; Costantino, Gabriele; Castagnolo, Daniele; Radi, Marco. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 57:13(2016), pp. 1464-1467. [10.1016/j.tetlet.2016.02.068]
A microwave-assisted multicomponent protocol for the synthesis of benzofuran-2-carboxamides
VINCETTI, Paolo;BRIANZA, ANNA;COSTANTINO, Gabriele;RADI, Marco
2016-01-01
Abstract
A fast, versatile and practical microwave-assisted multicomponent protocol for the synthesis of substituted benzofuran-2-carboxamides has been developed. The present method proved to be effective on a series of commercially available amines, 2′-hydroxyacetophenones, aldehydes, and benzonitriles and could be exploited in drug-discovery campaigns for the rapid identification of biologically active hit compounds.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
