IRIS
ROTI, Giovanni
 Distribuzione geografica
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Continente #
NA - Nord America 2.409
EU - Europa 2.247
AS - Asia 1.271
AF - Africa 32
SA - Sud America 12
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.977
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Nazione #
US - Stati Uniti d'America 2.383
CN - Cina 686
IT - Italia 603
IE - Irlanda 486
SG - Singapore 448
SE - Svezia 353
DE - Germania 205
FI - Finlandia 146
UA - Ucraina 138
TR - Turchia 83
AT - Austria 79
FR - Francia 71
GB - Regno Unito 48
IN - India 34
NL - Olanda 30
CI - Costa d'Avorio 29
BE - Belgio 23
CA - Canada 22
CZ - Repubblica Ceca 14
RU - Federazione Russa 12
BR - Brasile 10
JP - Giappone 8
IR - Iran 6
AU - Australia 5
LU - Lussemburgo 5
RO - Romania 5
LT - Lituania 4
PA - Panama 4
CH - Svizzera 3
ES - Italia 3
HU - Ungheria 3
BG - Bulgaria 2
GR - Grecia 2
HK - Hong Kong 2
MA - Marocco 2
MD - Moldavia 2
PL - Polonia 2
RS - Serbia 2
AL - Albania 1
AZ - Azerbaigian 1
BH - Bahrain 1
BO - Bolivia 1
DK - Danimarca 1
EG - Egitto 1
EU - Europa 1
HR - Croazia 1
IL - Israele 1
LV - Lettonia 1
NO - Norvegia 1
PE - Perù 1
PH - Filippine 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 5.977
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Città #
Dublin 486
Chandler 472
Singapore 358
Ashburn 231
Boardman 187
Parma 180
Jacksonville 135
Beijing 132
Ann Arbor 126
Dearborn 105
Princeton 90
Nanjing 84
Shanghai 76
Vienna 72
Izmir 71
Wilmington 62
Grafing 53
San Mateo 50
Shenyang 49
Marseille 48
Helsinki 46
Jinan 44
Nanchang 41
New York 36
Bologna 35
Milan 33
Hebei 32
Abidjan 29
Seattle 26
Santa Clara 25
Brussels 20
Changsha 20
Des Moines 20
Guangzhou 20
Hefei 20
Kunming 20
Verona 20
Amsterdam 19
Munich 19
Tianjin 19
Toronto 18
Bremen 17
Los Angeles 17
Pune 17
Fremont 16
Jiaxing 16
West Jordan 14
Dallas 13
Norwalk 13
Perugia 13
Brno 12
Chicago 11
Modena 11
Rome 11
Woodbridge 11
Hangzhou 10
Houston 10
Brescia 9
Carpi 9
Düsseldorf 9
Haikou 9
Trento 9
Zhengzhou 9
Kocaeli 8
Reggio Emilia 8
Auburn Hills 7
London 7
Ningbo 7
Turin 7
Frankfurt am Main 6
Bolzano 5
Florence 5
Lanzhou 5
Mestre 5
Trieste 5
Assago 4
Augusta 4
Boretto 4
Chengdu 4
Cordovado 4
Fairfield 4
Istanbul 4
Leipzig 4
Magdeburg 4
Neviano degli Arduini 4
Redwood City 4
Rockville 4
Rovereto 4
Arezzo 3
Budapest 3
Camerino 3
Falls Church 3
Fidenza 3
Kolkata 3
Kyiv 3
Kyoto 3
Licata 3
Melbourne 3
Orzinuovi 3
Piacenza 3
Totale 4.058
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Nome #
Validation of a radiomic approach to decipher NSCLC immune microenvironment in surgically resected patients 122
Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia 117
Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia 117
Targeting oncogenic Notch signaling with SERCA inhibitors 111
Human myeloma cells produce angiopoietin-1 but not angiopoietin-2: potential relationship with myeloma-induced angiogenesis 95
Bone marrow endothelial cells carry bcr/abl fusion gene from chronic myeloid leukemia patients 93
Bone marrow endothelial cells carry bcr/abl fusion gene from chronic myeloid leukemia patients 92
BCR/ABL fusion gene is detected in chronic myeloid leukemia endothelial cells 91
Angiopoietins expression by human myeloma cells 90
Bone marrow endothelial cells carry bcr/abl fusion gene from chronic myeloid leukemia patients 90
238P Exploring blood immune cell dynamics to unravel the immunomodulatory effect of radiotherapy in NSCLC patients undergoing immune checkpoint inhibitors 87
IL-7 is induced by IL-6 in human myeloma cells: role in multiple myeloma 86
Down-Modulation of Erk Protein Kinase Activity Inhibits Vascular Endothelial Growth Factor (VEGF) Secretion by human Myeloma Cell Lines 84
Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia 82
Hematologic malignancies with extramedullary spread of disease. Case 1. Multiple myeloma with extramedullary involvement of the pleura and testes 82
Impact of the rs1024611 polymorphism of ccl2 on the pathophysiology and outcome of primary myelofibrosis 82
IL-7 is produced by myeloma cells in presence of IL-6 79
Pro-angiogenetic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship with myeloma-induced angiogenesis 79
LONGITUDINAL MONITORING OF RADIOMIC AND BLOOD IMMUNE-INFLAMMATORY DESCRIPTORS AS A NON-INVASIVE APPROACH TO PREDICT ICI EFFICACY IN ADVANCED NSCLC PATIENTS 76
VASCULAR ENDOTHELIAL GROWTH FACTOR SECRETION BY MYELOMA CELLS IS INHIBITED BY DOWN-MODULATING ERK PROTEIN KINASE ACTIVITY 76
Osteopontin is produced by human multiple myeloma cells 75
Multiple myeloma patient with unusual extramedullary involvement 75
Integrated CT imaging and tissue immune features disclose a radio-immune signature with high prognostic impact on surgically resected NSCLC 75
Acute lymphoblastic leukaemia in Noonan syndrome. 74
Dynamic Profiling of Blood Immunophenotypes and Radiomic Features to Predict Immunotherapy Response in Advanced Non-small Cell Lung Cancer 73
Paracrine rather than autocrine basic FGF (bFGF) loop in multiple myeloma 71
Multiple Myeloma patient with unusual extramedullary involvement 70
Human myeloma cells production of angiopoietin-1 and its potential relationship with myeloma-induced angiogenesis 69
Chemical Genomic Screen Identifies Ionophores as Modulators of Notch1 in T-ALL 68
BCR/ABL fusion gene is detected in chronic myeloid leukemia endothelial cells 67
Human myeloma cells production of angiopoietin-1 and its potential relationship with myeloma-induced angiogenesis 66
Multiple myeloma patient with unusual extramedullary involvement 66
Dataset on the identification of a prognostic radio-immune signature in surgically resected Non Small Cell Lung Cancer 66
17P Dynamic changes of CT-radiomic and systemic immune-inflammatory features predict the response to immune checkpoint inhibitors in advanced NSCLC patients 66
Human myeloma cells express IL-7 mRNA and secrete IL-7 in presence of IL-6 65
Synergistic drug combinations with a CDK4/6 inhibitor in T-cell acute lymphoblastic leukemia 65
P1.15-04 Dynamic Profiling of Blood Immunophenotypes and Radiomic Features to Predict Immunotherapy Response in Advanced Non-small Cell Lung Cancer 64
IL-7 is produced by myeloma cells in presence of IL-6 64
Down-modulation of ERK protein kinase activity suppresses human myeloma cell proliferation and myeloma-induced angiogenesis by VEGF inhibition 63
Activating somatic and germline TERT promoter variants in myeloid malignancies 63
MYB rearrangements and over-expression in T-cell acute lymphoblastic leukemia 62
Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling 61
Down-modulation of ERK protein kinase activity inhibits vascular endothelial growth factor (VEGF) secretion by human myeloma cell lines 60
Genetic and proteomic approaches to identify cancer drug targets. 59
Strategies to Overcome Resistance Mechanisms in T-Cell Acute Lymphoblastic Leukemia 59
Cryptic chromosome 9q34 deletion generates TAF-Ialpha/CAN and TAF-Ibeta/CAN fusion transcripts in acute myeloid leukemia. 59
Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia 59
Paracrine rather than autocrine basic FGF (bFGF) loop in multiple myeloma 58
Bone marrow endothelial cells carry BCR/ABL fusion gene from chronic myeloid leukemia patients. 57
14q32 rearrangements deregulating BCL11B mark a distinct subgroup of T-lymphoid and myeloid immature acute leukemia 56
Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. 55
Orthogonal Proteogenomic Approaches Identify the Druggable PA2G4-MYC Axis in 3q26 AML 54
Leukemia-specific delivery of mutant NOT CH1 targeted therapy 53
Haploidentical hematopoietic stem cell transplantation in adults using the αβTCR/CD19-based depletion of G-CSF-mobilized peripheral blood progenitor cells 53
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. 52
Targeting Notch Trafficking and Processing in Cancers 52
Genetic profile of acute lymphoblastic leukemia in a patient with the noonan syndrome 51
Down-modulation of ERK protein kinase activity inhibits vascular endothelial growth factor (VEGF) secretion by human myeloma cell lines. 51
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. 51
Bepridil exhibits anti-leukemic activity associated with NOTCH1 pathway inhibition in chronic lymphocytic leukemia 51
227P Sexual dimorphism in immune profile of early and advanced NSCLC 50
Bilateral tonsillar infiltration of T-cell prolymphocytic leukemia 50
THERAPEUTIC TARGETING OF NOTCH SIGNALING PATHWAY IN HEMATOLOGICAL MALIGNANCIES 50
Constitutive phosphorylation of Janus kinase2 in the GL15 glioblastoma derived human cell line 46
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro 45
Venetoclax and bortezomib in relapsed/refractory early t-cell precursor acute lymphoblastic leukemia 45
Identification of the Atypical Protein Kinase WNK1 As a New Target in T-Cell Acute Lymphoblastic Leukemia 44
Cytoplasmic nucleophosmin in myeloid sarcoma occurring 20 years after diagnosis of acute myeloid leukaemia. 44
Differentially regulated high-throughput CT imaging features correlate to distinct tumor immune contextures portraying a radiomic signature with prognostic impact on surgically resected NSCLC 44
e6a2 BCR/ABL1 fusion with cryptic der(9)t(9;22) deletions in a patient with chronic myeloid leukemia 43
A distinct epigenetic program underlies the 1;7 translocation in myelodysplastic syndromes 42
2315P Clinical and blood immune-inflammatory profiling to decode different patterns of acquired resistance in immunotherapy treated NSCLC patients 41
A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome 41
Nivolumab-Induced Guillain-Barré Syndrome Coupled With Remarkable Disease Response in a Case of Heavily Pretreated Lung Adenocarcinoma 41
WO/2016/073708 41
Cytogenetic/mutation profile of chronic lymphocytic leukemia/malignant melanoma collision tumors of the skin 40
The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. 39
DHPLC analysis of NPM1 mutations in adult primary AML. 39
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma 39
Morphological, clinical, and molecular profiling of post-polycythemia vera accelerated/blast phase occurring with and without antecedent secondary myelofibrosis 38
Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E 37
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. 35
Lenvatinib Targets PDGFR-β Pericytes and Inhibits Synergy with Thyroid Carcinoma Cells: Novel Translational Insights 35
Expression-Based Screen Identifies the Calcium Channel Antagonist Bepridil as a Notch1 Modulator in T-ALL 34
Modulating Notch1 With Signature-based Small Molecule Library Screening 33
Genetic pathways in low-and high-grade HCV-related lymphomas are different 33
Mutational analisys of JAK2 VAL617PHE in a new series of chronic myelomonocytic leukemia and related atypical myeloproliferative disorders 33
The Folate Cycle Enzyme MTHFR is a Critical Regulator of Cell Response to MYC-Targeting Therapies 33
189P The parallel interrogation of tissue and peripheral blood immune features unveils a bidirectional crosstalk with clinical impact on resected NSCLC 32
Targeting NOTCH1 in hematopoietic malignancy. 32
Denaturing high-performance liquid chromatography: a valid approach for identifying NPM1 mutations in Acute Myeloid Leukemia 32
NPM1 haploinsufficiency in MDS/AML with del(5q)/monosomy 5 30
High PIM1 expression is a biomarker of T-cell acute lymphoblastic leukemia with JAK/STAT activation or t(6;7)(p21;q34)/TRB@-PIM1 rearrangement 30
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line 28
SERCA MODULATION COUNTERACTS GLUCOCORTICOID RESISTANCE IN T-ALL 28
Phase I trial of the mTOR inhibitor everolimus in combination with multi-agent chemotherapy in relapsed childhood acute lymphoblastic leukemia 28
New somatic TERT promoter variants enhance the Telomerase activity in Glioblastoma 28
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations 27
Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy 27
CAD204520 Targets NOTCH1 PEST Domain Mutations in Lymphoproliferative Disorders 26
Totale 5.792
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Categoria #
all - tutte 25.826
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 25.826
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020476 0 0 0 0 58 83 64 19 35 133 38 46
2020/2021515 16 33 38 20 56 17 34 23 128 47 78 25
2021/2022517 16 16 11 15 7 64 72 55 27 40 32 162
2022/20231.922 219 191 106 124 206 206 32 117 585 7 82 47
2023/2024987 50 64 29 41 85 184 124 80 40 72 72 146
2024/2025941 90 164 215 235 237 0 0 0 0 0 0 0
Totale 6.128