IRIS
TAGLIAZUCCHI, LORENZO
 Distribuzione geografica
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Continente #
AS - Asia 895
NA - Nord America 751
EU - Europa 233
Continente sconosciuto - Info sul continente non disponibili 69
SA - Sud America 50
AF - Africa 20
Totale 2.018
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Nazione #
US - Stati Uniti d'America 709
SG - Singapore 317
VN - Vietnam 253
CN - Cina 173
IT - Italia 157
BD - Bangladesh 55
HK - Hong Kong 44
FR - Francia 23
BR - Brasile 21
CA - Canada 18
MX - Messico 11
AR - Argentina 10
DE - Germania 9
NL - Olanda 8
FI - Finlandia 7
GB - Regno Unito 7
IE - Irlanda 7
IN - India 6
JP - Giappone 6
TH - Thailandia 6
SC - Seychelles 5
IQ - Iraq 4
JO - Giordania 4
PH - Filippine 4
UY - Uruguay 4
ZA - Sudafrica 4
CL - Cile 3
EC - Ecuador 3
ES - Italia 3
JM - Giamaica 3
KR - Corea 3
MA - Marocco 3
SA - Arabia Saudita 3
UA - Ucraina 3
AE - Emirati Arabi Uniti 2
CO - Colombia 2
CR - Costa Rica 2
DZ - Algeria 2
HN - Honduras 2
KE - Kenya 2
LB - Libano 2
PE - Perù 2
PK - Pakistan 2
PL - Polonia 2
PR - Porto Rico 2
SE - Svezia 2
SN - Senegal 2
TR - Turchia 2
UZ - Uzbekistan 2
VE - Venezuela 2
AZ - Azerbaigian 1
BB - Barbados 1
BE - Belgio 1
BO - Bolivia 1
CI - Costa d'Avorio 1
DO - Repubblica Dominicana 1
EG - Egitto 1
GT - Guatemala 1
GY - Guiana 1
LC - Santa Lucia 1
LT - Lituania 1
LV - Lettonia 1
MT - Malta 1
MY - Malesia 1
NP - Nepal 1
OM - Oman 1
PS - Palestinian Territory 1
PT - Portogallo 1
PY - Paraguay 1
QA - Qatar 1
TW - Taiwan 1
Totale 1.949
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Città #
San Jose 214
Council Bluffs 181
Singapore 141
Hanoi 67
Ho Chi Minh City 63
Hong Kong 35
Santa Clara 35
Beijing 29
Boardman 29
Ashburn 26
Lauterbourg 17
Milan 16
Los Angeles 15
Parma 15
Bologna 14
Phoenix 12
Da Nang 11
Rome 11
Hillsboro 10
Haiphong 8
Modena 7
New York 7
Dublin 6
Helsinki 6
Pittsburgh 6
Chicago 5
Guadalajara 5
Shanghai 5
Amman 4
Charlotte 4
Figino 4
Honolulu 4
Houston 4
Joliet 4
Mantua 4
Montevideo 4
Montreal 4
Seattle 4
Toronto 4
Amsterdam 3
Baghdad 3
Biên Hòa 3
Bến Tre 3
Can Tho 3
Curitiba 3
Dallas 3
Dhaka 3
Georgetown 3
Johannesburg 3
Las Vegas 3
Louisville 3
Munich 3
Naples 3
New Orleans 3
Newark 3
Phủ Lý 3
Reggio Emilia 3
Richlands 3
Thomasville 3
Tân Tiến 3
Vĩnh Long 3
Abbeville 2
Abilene 2
Anchorage 2
Antioch 2
Baton Rouge 2
Blumenau 2
Boston 2
Buffalo 2
Burlington 2
Bắc Giang 2
Bắc Ninh 2
Casablanca 2
Ceres 2
Chevy Chase 2
Dakar 2
Denver 2
Elk Grove Village 2
Fostoria 2
Frankfurt am Main 2
Genoa 2
Harringay 2
Harrisburg 2
Hobart 2
Huaraz 2
Lake Worth 2
Lexington 2
Madrid 2
Memphis 2
Mexico City 2
Milwaukee 2
Nairobi 2
Nilópolis 2
Pageland 2
Palermo 2
Philadelphia 2
Quận Bình Thạnh 2
San Diego 2
San Pedro Sula 2
Santa Ana 2
Totale 1.184
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Nome #
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 116
The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors 106
Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics 65
One Health science and technology in the development of safer antiparasitic drugs. 60
Drug discovery of pyrazolo-piperidinone inhibitors targeting YAP:TEAD interaction and development of a fluorescence anisotropy assay for high-throughput screening 51
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 50
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells 48
Mass Spectrometry Proteomics: A Key to Faster Drug Discovery 48
Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo 44
Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations 40
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 40
Expression, purification, and characterization of Transcriptional Enhancer Associated Domain (hTEAD4), a promising target for anticancer agents 37
Leveraging proteomic, bioinformatic and ecotoxicology models to select new targets overcoming L. Infantum drug resistent 36
Efficacy and risks: the other side of One Health drugs 35
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 35
Current Treatments to Control African Trypanosomiasis and One Health Perspective 35
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents 34
Development of guanidino-containing benzimidazoles as novel folate enzymes inhibitors for the treatment of Human African Trypanosomiasis 32
Advancing sustainable drug development: comparative preclinical study of H80 and Miltefosine using imaging and proteomics 30
Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance 30
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 30
Characterization and Valorization of the Agricultural Waste Obtained from Lavandula Steam Distillation for Its Reuse in the Food and Pharmaceutical Fields 30
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery–Genetics Alliance Perspective 30
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 30
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 29
Targeting the YAP:TEAD domain through fluorescence-anisotropy displacement assay 29
A dual-Omics approach to identify the modulated proteins/genes in THP-1 cells infected with different drug resistant L. infantum clinical isolates 28
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 28
Exploring thymidylate synthase mRNA binding site 1 and human TS protein interaction with optical tweezers and bicistronic expression assay 27
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 27
One Health Approach in Drug Discovery for Leishmaniasis by Targeting Calpain cys-protease 27
Applying optical tweezers technology to reveal Thymidylate Synthase interactions with its consensus mRNA 26
Development of a fluorescent anisotropy displacement assay for the optimization of YAP:TEAD molecular disrupters with anticancer activity 26
Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes 26
Folic Acid–Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 25
Proteomic contribution to the omic path for the identification of novel drugs overcoming resistance in Leishmaniasis 25
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 25
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 25
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 25
Precision medicine through proteomics studies in drug resistant colorectal cancer 24
Discovery of guanidino-containing benzimidazoles as novel antifolates for Trypanosomiasis 24
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 24
Preclinical investigation of H80 compared to miltefosine: imaging and proteomics for sustainable drug development 23
Promoting A Sustainable Medicinal Chemistry Approach With The Cost Action CA21111 - One Health Drugs Against Parasitic Vector Borne Diseases In Europe And Beyond 22
UHPLC-MS/MS screening of the hTEAD surface for the identification of novel allosteric inhibitors with anticancer activity 22
LC-MS/MS Helps Characterizing THP-1 Cells Proteome After Infection with Drug Resistant Leishmania Strains 22
Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates 22
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase 22
Investigating the mechanism of action of the antiparasitic agent H80 through imaging techniques 21
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 21
EXPLOITING THE OPTICAL TWEEZER, A SINGLE MOLECULE TECHNOLOGY, TO REVEAL THYMIDYLATE SYNTHASE INTERACTIONS WITH ITS CONSENSUS mRNA 21
Coupling a microwave-assisted process with HPLC-ELSD for the extraction, purification and analysis of bioactive policosanols from beeswax 21
Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases 20
LC-MS/MS proteomics for the rapid and selective screening of drug resistances in Leishmania infantum clinical isolates 20
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 20
Targeting of the Cysteines Surface domain of the Transcriptional Enhancer Associate Domain (TEAD) for anticancer drug discovery 20
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 20
Insights into host-target interaction from the proteome modulation analysis through untargeted LC-MS/MS Proteomics of drug resistant L infantum-THP1 infected cells 19
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 19
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 19
Exploiting Forster Resonance Energy Transfer (FRET) in the characterization of YAP:TEAD complex disruption 18
Leveraging proteomics, bioinformatics, and ecotoxicology models to select new targets overcoming L infantum drug resistance 18
Optimization of chemical-biological tools for characterizing the activity of dissociative inhibitor of human thymidylate synthase 17
Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA 15
A stretch-responsive fibroblast program promotes epidermal stem cell self-renewal during skin expansion 14
Totale 2.018
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Categoria #
all - tutte 9.166
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 9.166
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2022/202314 0 0 0 0 1 4 0 0 6 0 2 1
2023/20247 1 0 0 1 1 0 0 1 1 1 1 0
2024/202530 2 1 1 2 2 2 0 4 6 2 2 6
2025/20261.494 6 5 7 6 16 10 432 149 459 211 91 102
2026/2027473 252 221 0 0 0 0 0 0 0 0 0 0
Totale 2.018