IRIS
TAGLIAZUCCHI, LORENZO
 Distribuzione geografica
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Continente #
AS - Asia 891
NA - Nord America 629
EU - Europa 222
Continente sconosciuto - Info sul continente non disponibili 69
SA - Sud America 50
AF - Africa 19
Totale 1.880
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Nazione #
US - Stati Uniti d'America 588
SG - Singapore 316
VN - Vietnam 253
CN - Cina 172
IT - Italia 148
BD - Bangladesh 53
HK - Hong Kong 44
FR - Francia 22
BR - Brasile 21
CA - Canada 18
MX - Messico 11
AR - Argentina 10
DE - Germania 9
NL - Olanda 8
FI - Finlandia 7
GB - Regno Unito 7
IE - Irlanda 7
IN - India 6
JP - Giappone 6
TH - Thailandia 6
IQ - Iraq 4
JO - Giordania 4
PH - Filippine 4
SC - Seychelles 4
UY - Uruguay 4
ZA - Sudafrica 4
CL - Cile 3
EC - Ecuador 3
ES - Italia 3
KR - Corea 3
MA - Marocco 3
SA - Arabia Saudita 3
UA - Ucraina 3
AE - Emirati Arabi Uniti 2
CO - Colombia 2
CR - Costa Rica 2
DZ - Algeria 2
HN - Honduras 2
JM - Giamaica 2
KE - Kenya 2
LB - Libano 2
PE - Perù 2
PK - Pakistan 2
PL - Polonia 2
PR - Porto Rico 2
SE - Svezia 2
SN - Senegal 2
TR - Turchia 2
UZ - Uzbekistan 2
VE - Venezuela 2
AZ - Azerbaigian 1
BB - Barbados 1
BE - Belgio 1
BO - Bolivia 1
CI - Costa d'Avorio 1
DO - Repubblica Dominicana 1
EG - Egitto 1
GT - Guatemala 1
GY - Guiana 1
LC - Santa Lucia 1
LT - Lituania 1
LV - Lettonia 1
MY - Malesia 1
NP - Nepal 1
OM - Oman 1
PS - Palestinian Territory 1
PT - Portogallo 1
PY - Paraguay 1
QA - Qatar 1
TW - Taiwan 1
Totale 1.811
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Città #
San Jose 196
Singapore 140
Council Bluffs 122
Hanoi 67
Ho Chi Minh City 63
Hong Kong 35
Beijing 29
Boardman 29
Ashburn 26
Lauterbourg 17
Milan 16
Los Angeles 15
Bologna 14
Parma 12
Da Nang 11
Hillsboro 10
Rome 10
Santa Clara 9
Haiphong 8
Modena 7
New York 7
Dublin 6
Helsinki 6
Pittsburgh 6
Chicago 5
Guadalajara 5
Amman 4
Charlotte 4
Figino 4
Honolulu 4
Houston 4
Joliet 4
Mantua 4
Montevideo 4
Montreal 4
Seattle 4
Shanghai 4
Toronto 4
Amsterdam 3
Baghdad 3
Biên Hòa 3
Bến Tre 3
Can Tho 3
Curitiba 3
Dallas 3
Dhaka 3
Georgetown 3
Johannesburg 3
Las Vegas 3
Louisville 3
Munich 3
Naples 3
New Orleans 3
Phủ Lý 3
Reggio Emilia 3
Richlands 3
Thomasville 3
Tân Tiến 3
Vĩnh Long 3
Abbeville 2
Abilene 2
Anchorage 2
Antioch 2
Baton Rouge 2
Blumenau 2
Boston 2
Burlington 2
Bắc Giang 2
Bắc Ninh 2
Casablanca 2
Ceres 2
Chevy Chase 2
Dakar 2
Denver 2
Elk Grove Village 2
Fostoria 2
Frankfurt am Main 2
Harringay 2
Harrisburg 2
Hobart 2
Huaraz 2
Lake Worth 2
Lexington 2
Madrid 2
Memphis 2
Mexico City 2
Milwaukee 2
Nairobi 2
Newark 2
Nilópolis 2
Pageland 2
Quận Bình Thạnh 2
San Diego 2
San Pedro Sula 2
Santa Ana 2
Santiago 2
Shreveport 2
Stuttgart 2
Tashkent 2
Thanh Mỹ Tây 2
Totale 1.064
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Nome #
Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library 114
The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors 105
Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics 64
One Health science and technology in the development of safer antiparasitic drugs. 59
Drug discovery of pyrazolo-piperidinone inhibitors targeting YAP:TEAD interaction and development of a fluorescence anisotropy assay for high-throughput screening 50
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 48
Mass Spectrometry Proteomics: A Key to Faster Drug Discovery 48
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells 46
Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo 42
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 35
Leveraging proteomic, bioinformatic and ecotoxicology models to select new targets overcoming L. Infantum drug resistent 35
Efficacy and risks: the other side of One Health drugs 33
Current Treatments to Control African Trypanosomiasis and One Health Perspective 33
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents 33
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 32
Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations 30
Development of guanidino-containing benzimidazoles as novel folate enzymes inhibitors for the treatment of Human African Trypanosomiasis 29
Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance 28
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 28
Characterization and Valorization of the Agricultural Waste Obtained from Lavandula Steam Distillation for Its Reuse in the Food and Pharmaceutical Fields 28
Advancing sustainable drug development: comparative preclinical study of H80 and Miltefosine using imaging and proteomics 27
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 27
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery–Genetics Alliance Perspective 27
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 27
Exploring thymidylate synthase mRNA binding site 1 and human TS protein interaction with optical tweezers and bicistronic expression assay 26
Expression, purification, and characterization of Transcriptional Enhancer Associated Domain (hTEAD4), a promising target for anticancer agents 26
One Health Approach in Drug Discovery for Leishmaniasis by Targeting Calpain cys-protease 26
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 25
A dual-Omics approach to identify the modulated proteins/genes in THP-1 cells infected with different drug resistant L. infantum clinical isolates 25
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 25
Folic Acid–Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 24
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 24
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 24
Development of a fluorescent anisotropy displacement assay for the optimization of YAP:TEAD molecular disrupters with anticancer activity 24
Targeting the YAP:TEAD domain through fluorescence-anisotropy displacement assay 24
Applying optical tweezers technology to reveal Thymidylate Synthase interactions with its consensus mRNA 23
Proteomic contribution to the omic path for the identification of novel drugs overcoming resistance in Leishmaniasis 23
Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes 23
Discovery of guanidino-containing benzimidazoles as novel antifolates for Trypanosomiasis 22
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 22
Precision medicine through proteomics studies in drug resistant colorectal cancer 21
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 21
LC-MS/MS Helps Characterizing THP-1 Cells Proteome After Infection with Drug Resistant Leishmania Strains 21
Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates 21
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase 21
Promoting A Sustainable Medicinal Chemistry Approach With The Cost Action CA21111 - One Health Drugs Against Parasitic Vector Borne Diseases In Europe And Beyond 20
Investigating the mechanism of action of the antiparasitic agent H80 through imaging techniques 20
UHPLC-MS/MS screening of the hTEAD surface for the identification of novel allosteric inhibitors with anticancer activity 20
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 20
EXPLOITING THE OPTICAL TWEEZER, A SINGLE MOLECULE TECHNOLOGY, TO REVEAL THYMIDYLATE SYNTHASE INTERACTIONS WITH ITS CONSENSUS mRNA 20
Preclinical investigation of H80 compared to miltefosine: imaging and proteomics for sustainable drug development 19
Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases 19
LC-MS/MS proteomics for the rapid and selective screening of drug resistances in Leishmania infantum clinical isolates 19
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 19
Targeting of the Cysteines Surface domain of the Transcriptional Enhancer Associate Domain (TEAD) for anticancer drug discovery 19
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 19
Coupling a microwave-assisted process with HPLC-ELSD for the extraction, purification and analysis of bioactive policosanols from beeswax 19
Insights into host-target interaction from the proteome modulation analysis through untargeted LC-MS/MS Proteomics of drug resistant L infantum-THP1 infected cells 18
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 18
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 18
Exploiting Forster Resonance Energy Transfer (FRET) in the characterization of YAP:TEAD complex disruption 17
Leveraging proteomics, bioinformatics, and ecotoxicology models to select new targets overcoming L infantum drug resistance 17
Optimization of chemical-biological tools for characterizing the activity of dissociative inhibitor of human thymidylate synthase 16
Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA 14
A stretch-responsive fibroblast program promotes epidermal stem cell self-renewal during skin expansion 10
Totale 1.880
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Categoria #
all - tutte 8.615
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 8.615
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2022/202314 0 0 0 0 1 4 0 0 6 0 2 1
2023/20247 1 0 0 1 1 0 0 1 1 1 1 0
2024/202530 2 1 1 2 2 2 0 4 6 2 2 6
2025/20261.494 6 5 7 6 16 10 432 149 459 211 91 102
2026/2027335 252 83 0 0 0 0 0 0 0 0 0 0
Totale 1.880