IRIS
TAGLIAZUCCHI, LORENZO
 Distribuzione geografica
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Continente #
AS - Asia 836
NA - Nord America 333
EU - Europa 130
SA - Sud America 41
AF - Africa 12
Totale 1.352
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Nazione #
US - Stati Uniti d'America 307
SG - Singapore 300
VN - Vietnam 244
CN - Cina 165
IT - Italia 77
BD - Bangladesh 44
HK - Hong Kong 35
FR - Francia 21
BR - Brasile 13
MX - Messico 11
AR - Argentina 10
CA - Canada 9
GB - Regno Unito 7
FI - Finlandia 6
IN - India 6
JP - Giappone 6
DE - Germania 5
NL - Olanda 5
TH - Thailandia 5
IQ - Iraq 4
JO - Giordania 4
PH - Filippine 4
UY - Uruguay 4
CL - Cile 3
KR - Corea 3
MA - Marocco 3
SA - Arabia Saudita 3
UA - Ucraina 3
CO - Colombia 2
DZ - Algeria 2
EC - Ecuador 2
JM - Giamaica 2
KE - Kenya 2
LB - Libano 2
PE - Perù 2
PK - Pakistan 2
PL - Polonia 2
PR - Porto Rico 2
SN - Senegal 2
UZ - Uzbekistan 2
VE - Venezuela 2
ZA - Sudafrica 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BE - Belgio 1
BO - Bolivia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
EG - Egitto 1
GY - Guiana 1
IE - Irlanda 1
LV - Lettonia 1
NP - Nepal 1
OM - Oman 1
PS - Palestinian Territory 1
PT - Portogallo 1
PY - Paraguay 1
TR - Turchia 1
TW - Taiwan 1
Totale 1.352
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Città #
San Jose 153
Singapore 133
Hanoi 65
Council Bluffs 62
Ho Chi Minh City 60
Hong Kong 30
Boardman 28
Beijing 27
Lauterbourg 17
Bologna 12
Da Nang 10
Hillsboro 10
Haiphong 8
Los Angeles 8
Ashburn 7
Helsinki 6
Pittsburgh 6
Guadalajara 5
Milan 5
New York 5
Amman 4
Montevideo 4
Santa Clara 4
Baghdad 3
Biên Hòa 3
Can Tho 3
Curitiba 3
Phủ Lý 3
Reggio Emilia 3
Rome 3
Toronto 3
Tân Tiến 3
Vĩnh Long 3
Amsterdam 2
Blumenau 2
Bắc Giang 2
Bắc Ninh 2
Bến Tre 2
Casablanca 2
Dakar 2
Dhaka 2
Frankfurt am Main 2
Harringay 2
Huaraz 2
Mexico City 2
Montreal 2
Nairobi 2
Naples 2
Parma 2
Quận Bình Thạnh 2
Santiago 2
Shanghai 2
Stuttgart 2
Tashkent 2
Thanh Mỹ Tây 2
Vũng Tàu 2
Điện Bàn 2
Acevedo 1
Ageo 1
Alajuela 1
Alexandria 1
Annaba 1
Augusta 1
Baku 1
Ban Khok 1
Beirut 1
Binangonan 1
Bloomingdale 1
Bogotá 1
Boston 1
Brasília 1
Brescia 1
Brusque 1
Buffalo 1
Buon Ma Thuot 1
Calgary 1
Caloocan 1
Capaccio Paestum 1
Cardiff 1
Chennai 1
Chicago 1
City of London 1
Ciudad Bolívar 1
Ciudad Nezahualcoyotl 1
Ciudad del Este 1
Colombo 1
Colón 1
Conceição do Coité 1
Constantine 1
Crofton 1
Córdoba 1
Dallas 1
Dammam 1
Donetsk 1
Dubai 1
Dublin 1
Enna 1
Ewarton 1
Fermo 1
Formosa 1
Totale 790
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Nome #
The rare bile acid isoallolithocholic acid (IALCA) is an EphA2 antagonist sparing FXR and TGR5 receptors 67
Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics 55
One Health science and technology in the development of safer antiparasitic drugs. 53
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth 45
Drug discovery of pyrazolo-piperidinone inhibitors targeting YAP:TEAD interaction and development of a fluorescence anisotropy assay for high-throughput screening 40
Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells 39
Identification of isoxazole-based TRPA1 inhibitors with analgesic effects in vivo 36
Mass Spectrometry Proteomics: A Key to Faster Drug Discovery 36
Leveraging proteomic, bioinformatic and ecotoxicology models to select new targets overcoming L. Infantum drug resistent 33
Designing selective Cys-ligands to unpair the binding of the Human Transcription Enhancer Associated Domain 4 (hTEAD-4) with its modulators to halt cancer cell growth 31
Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents 31
Development of a novel class of YAP:TEAD interface-3 molecular disruptors to treat colorectal carcinoma 26
A toolbox of biophysical and analytical assays helps to confirm the activity of novel hTS dimer disrupters (Ddis) with anticancer properties 26
Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations 25
Development of guanidino-containing benzimidazoles as novel folate enzymes inhibitors for the treatment of Human African Trypanosomiasis 25
Efficacy and risks: the other side of One Health drugs 25
Deciphering Host–Parasite Interplay in Leishmania Infection through a One Health View of Proteomics Studies on Drug Resistance 25
Current Treatments to Control African Trypanosomiasis and One Health Perspective 25
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery–Genetics Alliance Perspective 25
Advancing sustainable drug development: comparative preclinical study of H80 and Miltefosine using imaging and proteomics 24
One Health Approach in Drug Discovery for Leishmaniasis by Targeting Calpain cys-protease 24
Cellular uptake and metabolic degradation of a conjugate of folic acid with an anticancer peptide targeting the human Thymidylate synthase enzyme 23
Development of a sensitive biochemical tool to assess the expression levels of recombinant ectopic proteins in in vitro engineered cellular systems 23
Characterization and Valorization of the Agricultural Waste Obtained from Lavandula Steam Distillation for Its Reuse in the Food and Pharmaceutical Fields 22
Folic Acid–Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting 21
design, synthesis and biological evaluation of novel YAP:TEAD complex disruptors for thetreatment of colorectal cancer 21
Exploring thymidylate synthase mRNA binding site 1 and human TS protein interaction with optical tweezers and bicistronic expression assay 20
Applying optical tweezers technology to reveal Thymidylate Synthase interactions with its consensus mRNA 20
Discovery of guanidino-containing benzimidazoles as novel antifolates for Trypanosomiasis 19
Development of a fluorescent anisotropy displacement assay for the optimization of YAP:TEAD molecular disrupters with anticancer activity 19
A dual-Omics approach to identify the modulated proteins/genes in THP-1 cells infected with different drug resistant L. infantum clinical isolates 19
Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates 19
Advances in the set-up of a fluorescence- anisotropy assay for the search of novel inhibitors of the tead-4 complexes 19
Precision medicine through proteomics studies in drug resistant colorectal cancer 18
Lead optimization of human thymidylate synthase dimer disrupters: from computational studies to evaluation of their biological profiles 18
Expression, purification, and characterization of Transcriptional Enhancer Associated Domain (hTEAD4), a promising target for anticancer agents 18
LC-MS serum proteomics reveals a panel of proteins prognostic of positive responsiveness to bevacizumab therapy in late-stages ovarian cancer patients 18
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents 18
Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation 18
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase 18
Promoting A Sustainable Medicinal Chemistry Approach With The Cost Action CA21111 - One Health Drugs Against Parasitic Vector Borne Diseases In Europe And Beyond 17
Proteomic contribution to the omic path for the identification of novel drugs overcoming resistance in Leishmaniasis 17
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma 17
Targeting the dimer-monomer equilibrium of thymidylate synthase, to accelerate protein degradation and cancer cell growth inhibition 17
Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases 17
Coupling a microwave-assisted process with HPLC-ELSD for the extraction, purification and analysis of bioactive policosanols from beeswax 17
MS Proteomics And Biochemical Characterization Of Thymidylate Synthase Dimer Destabilizer E7 To Halt Colorectal Carcinoma 17
LC-MS/MS proteomics for the rapid and selective screening of drug resistances in Leishmania infantum clinical isolates 16
Integrating MS proteomics in the Medicinal Chemistry pipeline as powerful tool to overcome drug resistance issues in colorectal cancer 16
LC-MS/MS Helps Characterizing THP-1 Cells Proteome After Infection with Drug Resistant Leishmania Strains 16
Targeting of the Cysteines Surface domain of the Transcriptional Enhancer Associate Domain (TEAD) for anticancer drug discovery 15
Lead-optimization process and characterization of the dissociative effect applied to new dimer disrupters of human Thymidylate Synthase 15
Investigating the mechanism of action of the antiparasitic agent H80 through imaging techniques 14
Structural insight into YAP-TEAD4 protein-protein interactions as target for cancer treatment 14
Leveraging proteomics, bioinformatics, and ecotoxicology models to select new targets overcoming L infantum drug resistance 14
EXPLOITING THE OPTICAL TWEEZER, A SINGLE MOLECULE TECHNOLOGY, TO REVEAL THYMIDYLATE SYNTHASE INTERACTIONS WITH ITS CONSENSUS mRNA 14
Optimization of chemical-biological tools for characterizing the activity of dissociative inhibitor of human thymidylate synthase 14
Exploiting Forster Resonance Energy Transfer (FRET) in the characterization of YAP:TEAD complex disruption 13
UHPLC-MS/MS screening of the hTEAD surface for the identification of novel allosteric inhibitors with anticancer activity 13
Insights into host-target interaction from the proteome modulation analysis through untargeted LC-MS/MS Proteomics of drug resistant L infantum-THP1 infected cells 13
Preclinical investigation of H80 compared to miltefosine: imaging and proteomics for sustainable drug development 12
Exploiting the Optical Tweezer technology to reveal thymidylate synthase interactions with its consensus mRNA 12
Totale 1.417
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Categoria #
all - tutte 5.141
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 5.141
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2025/20261.417 0 0 0 0 8 7 423 147 450 204 91 87
Totale 1.417