CAMPANINI, Barbara
CAMPANINI, Barbara
Dipartimento di Scienze degli Alimenti e del Farmaco
A competitive o‐acetylserine sulfhydrylase inhibitor modulates the formation of cysteine synthase complex
2021-01-01 Marchetti, M.; De Angelis, F. S.; Annunziato, G.; Costantino, G.; Pieroni, M.; Ronda, L.; Mozzarelli, A.; Campanini, B.; Cannistraro, S.; Bizzarri, A. R.; Bettati, S.
A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme
2021-01-01 Marchesani, F.; Zangelmi, E.; Bruno, S.; Bettati, S.; Peracchi, A.; Campanini, B.
A novel Bim-BH3-derived Bcl-XL inhibitor: biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity
2008-01-01 R., Ponassi; B., Biasotti; V., Tomati; S., Bruno; A., Poggi; D., Malacarne; G., Cimoli; A., Salis; S., Pozzi; M., Miglino; G., Damonte; Cozzini, Pietro; Spyrakis, Francesca; Campanini, Barbara; L., Bagnasco; N., Castagnino; L., Tortolina; A., Mumot; F., Frassoni; A., Daga; M., Cilli; F., Piccardi; I., Monfardini; M., Perugini; G., Zoppoli; C., D'Arrigo; R., Pesenti; S., Parodi
A two-step process controls the formation of the bienzyme cysteine synthase complex
2010-01-01 E., Salsi; Campanini, Barbara; Bettati, Stefano; Raboni, Samanta; Sl, Roderick; Pf, Cook; Mozzarelli, Andrea
Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase
2017-01-01 Benoni, Roberto; Beck, Christina M.; Garza-Sánchez, Fernando; Bettati, Stefano; Mozzarelli, Andrea; Hayes, Christopher S.; Campanini, Barbara
Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution
2013-01-01 Campanini, Barbara; Bettati, Stefano; Martino Luigi di, Salvo; Mozzarelli, Andrea; Roberto, Contestabile
ATP binding to human serine racemase is cooperative and modulated by glycine
2013-01-01 Marchetti, Marialaura; Bruno, Stefano; Campanini, Barbara; Peracchi, Alessio; Mai, N; Mozzarelli, Andrea
Birth of a pathway for sulfur metabolism in early amniote evolution
2020-01-01 Malatesta, M; Mori, G; Acquotti, D; Campanini, B; Peracchi, A; Antin, P B; Percudani, R
Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor
2024-01-01 Marchesani, Francesco; Rebecchi, Francesca; Pieroni, Marco; Faggiano, Serena; Annunziato, Giannamaria; Spaggiari, Chiara; Bruno, Stefano; Rinaldi, Sofia; Giaccari, Roberta; Costantino, Gabriele; Campanini, Barbara
Combination of SAXS and protein painting discloses the three-dimensional organization of the bacterial cysteine synthase complex, a potential target for enhancers of antibiotic action
2019-01-01 Rosa, B.; Marchetti, M.; Paredi, G.; Amenitsch, H.; Franko, N.; Benoni, R.; Giabbai, B.; De Marino, M. G.; Mozzarelli, A.; Ronda, L.; Storici, P.; Campanini, B.; Bettati, S.
Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction
2022-01-01 DE BEI, Omar; Marchetti, Marialaura; Ronda, Luca; Gianquinto, Eleonora; Lazzarato, Loretta; Chirgadze, Dimitri Y.; Hadwick, Steven W.; Cooper, Lee R.; Spyrakis, Francesca; Luisi, Ben F.; Campanini, Barbara; Bettati, Stefano
Cryo-EM undiscloses structural and mechanistic details on iron hijacking by Staphylococcus aureus: An insight into the interaction of IsdB hemophore with human hemoglobin
2023-01-01 Marchetti, M; De Bei, O; Ronda, L; Gianquinto, E; Lazzarato, L; Chirgadze, Dy; Hardwick, Sw; Cooper, Lr; Cozzi, M; Faggiano, S; Spyrakis, F; Luisi, Bf; Campanini, B; Bettati, S
Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target
2016-01-01 Beato, Claudia; Pecchini, Chiara; Cocconcelli, Chiara; Campanini, Barbara; Marchetti, Marialaura; Pieroni, Marco; Mozzarelli, Andrea; Costantino, Gabriele
Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR
2016-01-01 Annunziato, Giannamaria; Pieroni, Marco; Benoni, Roberto; Campanini, Barbara; Pertinhez, Thelma; Pecchini, Chiara; Bruno, Agostino; Magalhães, Joana; Bettati, Stefano; Franko, Nina; Mozzarelli, Andrea; Costantino, Gabriele
Design and synthesis of trans-2-substituted-cyclopropane-1-carboxylic acids as the first non-natural small molecule inhibitors of O-acetylserine sulfhydrylase
2012-01-01 Amori, Laura; S., Katkevica; Bruno, Agostino; Campanini, Barbara; Felici, Paolo; Mozzarelli, Andrea; Costantino, Gabriele
Design of O-acetylserine sulfhydrylase inhibitors by mimicking Nature.
2010-01-01 E., Salsi; A., Bayden; Spyrakis, Francesca; A., Amadasi; Campanini, Barbara; Bettati, Stefano; Cozzini, Pietro; G. E., Kellogg; P. F., Cook; T., Dodatko; S. L., Roderick; Mozzarelli, Andrea
Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design
2018-01-01 Magalhães, Joana; Franko, Nina; Annunziato, Giannamaria; Welch, Martin; Dolan, Stephen K.; Bruno, Agostino; Mozzarelli, Andrea; Armao, Stefano; Jirgensons, Aigars; Pieroni, Marco; Costantino, Gabriele; Campanini, Barbara
Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants
2021-01-01 Magalhães, Joana; Franko, Nina; Raboni, Samanta; Annunziato, Giannamaria; Tammela, Päivi; Bruno, Agostino; Bettati, Stefano; Armao, Stefano; Spadini, Costanza; Cabassi, Clotilde Silvia; Mozzarelli, Andrea; Pieroni, Marco; Campanini, Barbara; Costantino, Gabriele
Dynamics of Green Fluorescent Protein Mutant2 in Solution, on Spin-coated Glasses and Encapsulated in Wet Silica Gels
2002-01-01 Chirico, G.; Cannone, F.; Beretta, S.; Diaspro, A.; Campanini, Barbara; Bettati, Stefano; Ruotolo, Roberta; Mozzarelli, Andrea
Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants
2024-01-01 Marchesani, Francesco; Comani, Valeria Buoli; Bruno, Stefano; Mozzarelli, Andrea; Carcelli, Mauro; Pollegioni, Loredano; Caldinelli, Laura; Peracchi, Alessio; Campanini, Barbara
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A competitive o‐acetylserine sulfhydrylase inhibitor modulates the formation of cysteine synthase complex | 1-gen-2021 | Marchetti, M.; De Angelis, F. S.; Annunziato, G.; Costantino, G.; Pieroni, M.; Ronda, L.; Mozzarelli, A.; Campanini, B.; Cannistraro, S.; Bizzarri, A. R.; Bettati, S. | |
| A novel assay for phosphoserine phosphatase exploiting serine acetyltransferase as the coupling enzyme | 1-gen-2021 | Marchesani, F.; Zangelmi, E.; Bruno, S.; Bettati, S.; Peracchi, A.; Campanini, B. | |
| A novel Bim-BH3-derived Bcl-XL inhibitor: biochemical characterization, in vitro, in vivo and ex-vivo anti-leukemic activity | 1-gen-2008 | R., Ponassi; B., Biasotti; V., Tomati; S., Bruno; A., Poggi; D., Malacarne; G., Cimoli; A., Salis; S., Pozzi; M., Miglino; G., Damonte; Cozzini, Pietro; Spyrakis, Francesca; Campanini, Barbara; L., Bagnasco; N., Castagnino; L., Tortolina; A., Mumot; F., Frassoni; A., Daga; M., Cilli; F., Piccardi; I., Monfardini; M., Perugini; G., Zoppoli; C., D'Arrigo; R., Pesenti; S., Parodi | |
| A two-step process controls the formation of the bienzyme cysteine synthase complex | 1-gen-2010 | E., Salsi; Campanini, Barbara; Bettati, Stefano; Raboni, Samanta; Sl, Roderick; Pf, Cook; Mozzarelli, Andrea | |
| Activation of an anti-bacterial toxin by the biosynthetic enzyme CysK: mechanism of binding, interaction specificity and competition with cysteine synthase | 1-gen-2017 | Benoni, Roberto; Beck, Christina M.; Garza-Sánchez, Fernando; Bettati, Stefano; Mozzarelli, Andrea; Hayes, Christopher S.; Campanini, Barbara | |
| Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution | 1-gen-2013 | Campanini, Barbara; Bettati, Stefano; Martino Luigi di, Salvo; Mozzarelli, Andrea; Roberto, Contestabile | |
| ATP binding to human serine racemase is cooperative and modulated by glycine | 1-gen-2013 | Marchetti, Marialaura; Bruno, Stefano; Campanini, Barbara; Peracchi, Alessio; Mai, N; Mozzarelli, Andrea | |
| Birth of a pathway for sulfur metabolism in early amniote evolution | 1-gen-2020 | Malatesta, M; Mori, G; Acquotti, D; Campanini, B; Peracchi, A; Antin, P B; Percudani, R | |
| Chemical Probes to Investigate Central Nervous System Disorders: Design, Synthesis and Mechanism of Action of a Potent Human Serine Racemase Inhibitor | 1-gen-2024 | Marchesani, Francesco; Rebecchi, Francesca; Pieroni, Marco; Faggiano, Serena; Annunziato, Giannamaria; Spaggiari, Chiara; Bruno, Stefano; Rinaldi, Sofia; Giaccari, Roberta; Costantino, Gabriele; Campanini, Barbara | |
| Combination of SAXS and protein painting discloses the three-dimensional organization of the bacterial cysteine synthase complex, a potential target for enhancers of antibiotic action | 1-gen-2019 | Rosa, B.; Marchetti, M.; Paredi, G.; Amenitsch, H.; Franko, N.; Benoni, R.; Giabbai, B.; De Marino, M. G.; Mozzarelli, A.; Ronda, L.; Storici, P.; Campanini, B.; Bettati, S. | |
| Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction | 1-gen-2022 | DE BEI, Omar; Marchetti, Marialaura; Ronda, Luca; Gianquinto, Eleonora; Lazzarato, Loretta; Chirgadze, Dimitri Y.; Hadwick, Steven W.; Cooper, Lee R.; Spyrakis, Francesca; Luisi, Ben F.; Campanini, Barbara; Bettati, Stefano | |
| Cryo-EM undiscloses structural and mechanistic details on iron hijacking by Staphylococcus aureus: An insight into the interaction of IsdB hemophore with human hemoglobin | 1-gen-2023 | Marchetti, M; De Bei, O; Ronda, L; Gianquinto, E; Lazzarato, L; Chirgadze, Dy; Hardwick, Sw; Cooper, Lr; Cozzi, M; Faggiano, S; Spyrakis, F; Luisi, Bf; Campanini, B; Bettati, S | |
| Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target | 1-gen-2016 | Beato, Claudia; Pecchini, Chiara; Cocconcelli, Chiara; Campanini, Barbara; Marchetti, Marialaura; Pieroni, Marco; Mozzarelli, Andrea; Costantino, Gabriele | |
| Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR | 1-gen-2016 | Annunziato, Giannamaria; Pieroni, Marco; Benoni, Roberto; Campanini, Barbara; Pertinhez, Thelma; Pecchini, Chiara; Bruno, Agostino; Magalhães, Joana; Bettati, Stefano; Franko, Nina; Mozzarelli, Andrea; Costantino, Gabriele | |
| Design and synthesis of trans-2-substituted-cyclopropane-1-carboxylic acids as the first non-natural small molecule inhibitors of O-acetylserine sulfhydrylase | 1-gen-2012 | Amori, Laura; S., Katkevica; Bruno, Agostino; Campanini, Barbara; Felici, Paolo; Mozzarelli, Andrea; Costantino, Gabriele | |
| Design of O-acetylserine sulfhydrylase inhibitors by mimicking Nature. | 1-gen-2010 | E., Salsi; A., Bayden; Spyrakis, Francesca; A., Amadasi; Campanini, Barbara; Bettati, Stefano; Cozzini, Pietro; G. E., Kellogg; P. F., Cook; T., Dodatko; S. L., Roderick; Mozzarelli, Andrea | |
| Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design | 1-gen-2018 | Magalhães, Joana; Franko, Nina; Annunziato, Giannamaria; Welch, Martin; Dolan, Stephen K.; Bruno, Agostino; Mozzarelli, Andrea; Armao, Stefano; Jirgensons, Aigars; Pieroni, Marco; Costantino, Gabriele; Campanini, Barbara | |
| Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants | 1-gen-2021 | Magalhães, Joana; Franko, Nina; Raboni, Samanta; Annunziato, Giannamaria; Tammela, Päivi; Bruno, Agostino; Bettati, Stefano; Armao, Stefano; Spadini, Costanza; Cabassi, Clotilde Silvia; Mozzarelli, Andrea; Pieroni, Marco; Campanini, Barbara; Costantino, Gabriele | |
| Dynamics of Green Fluorescent Protein Mutant2 in Solution, on Spin-coated Glasses and Encapsulated in Wet Silica Gels | 1-gen-2002 | Chirico, G.; Cannone, F.; Beretta, S.; Diaspro, A.; Campanini, Barbara; Bettati, Stefano; Ruotolo, Roberta; Mozzarelli, Andrea | |
| Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants | 1-gen-2024 | Marchesani, Francesco; Comani, Valeria Buoli; Bruno, Stefano; Mozzarelli, Andrea; Carcelli, Mauro; Pollegioni, Loredano; Caldinelli, Laura; Peracchi, Alessio; Campanini, Barbara |