BETTUZZI, Saverio
 Distribuzione geografica
Continente #
NA - Nord America 5.070
EU - Europa 4.266
AS - Asia 1.912
Continente sconosciuto - Info sul continente non disponibili 12
OC - Oceania 10
SA - Sud America 5
AF - Africa 4
Totale 11.279
Nazione #
US - Stati Uniti d'America 4.930
CN - Cina 1.561
IE - Irlanda 956
UA - Ucraina 732
SE - Svezia 624
FI - Finlandia 615
IT - Italia 562
DE - Germania 417
CA - Canada 140
TR - Turchia 139
AT - Austria 126
FR - Francia 75
IR - Iran 67
GB - Regno Unito 63
SG - Singapore 63
IN - India 43
BE - Belgio 31
VN - Vietnam 14
NL - Olanda 13
EU - Europa 12
CZ - Repubblica Ceca 10
SK - Slovacchia (Repubblica Slovacca) 10
JP - Giappone 7
KR - Corea 7
AU - Australia 6
RO - Romania 6
CH - Svizzera 5
BR - Brasile 4
NZ - Nuova Zelanda 4
BG - Bulgaria 3
DK - Danimarca 3
EE - Estonia 2
HK - Hong Kong 2
HR - Croazia 2
HU - Ungheria 2
IL - Israele 2
KZ - Kazakistan 2
LU - Lussemburgo 2
PL - Polonia 2
RU - Federazione Russa 2
AE - Emirati Arabi Uniti 1
CO - Colombia 1
DZ - Algeria 1
EG - Egitto 1
ES - Italia 1
KE - Kenya 1
MD - Moldavia 1
NG - Nigeria 1
NP - Nepal 1
PT - Portogallo 1
SA - Arabia Saudita 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
Totale 11.279
Città #
Dublin 956
Jacksonville 866
Chandler 833
Dearborn 509
Ashburn 361
Beijing 361
Nanjing 272
Ann Arbor 248
San Mateo 224
Princeton 211
Parma 153
Toronto 120
Wilmington 116
Vienna 115
Izmir 113
Shenyang 96
Nanchang 95
Jinan 78
Hebei 73
Helsinki 70
Leawood 67
Hefei 66
Des Moines 64
Kunming 61
Shanghai 56
Boardman 50
Jiaxing 49
Tianjin 45
Changsha 42
Augusta 35
Guangzhou 35
Houston 32
Fremont 31
New York 31
Ardabil 30
Brussels 30
Haikou 30
Woodbridge 29
Milan 28
Seattle 28
Zhengzhou 24
Kocaeli 23
Norwalk 21
Rome 21
Ardea 20
Monmouth Junction 19
Hangzhou 16
Grafing 15
Chengdu 14
Dong Ket 14
Falls Church 14
Modena 14
Taiyuan 14
Redmond 13
Bologna 12
Mumbai 12
Trieste 12
Zanjan 12
Piacenza 11
Taizhou 11
Chicago 10
Lanzhou 10
Sacramento 10
Bratislava 9
Chongqing 8
Fuzhou 8
Ningbo 8
Andover 7
Singapore 7
Bremen 6
Düsseldorf 6
Padova 6
Auburn Hills 5
Brno 5
Brooklyn 5
Los Angeles 5
Mestre 5
New Delhi 5
Pune 5
Rockville 5
Sassari 5
Tokyo 5
Washington 5
Wenzhou 5
Xian 5
Adelaide 4
Amsterdam 4
Arnstadt 4
Avellino 4
Baotou 4
Chaoyang 4
Fairfield 4
Las Vegas 4
Ottawa 4
Quzhou 4
Shaoxing 4
Winnipeg 4
Wuhan 4
Borås 3
Copenhagen 3
Totale 7.239
Nome #
Flavonoids as epigenetic modulators for prostate cancer prevention 145
Effects of standardized green tea extract and its main component, EGCG, on mitochondrial function and contractile performance of healthy rat cardiomyocytes 138
Long-Term Oral Administration of Theaphenon-E Improves Cardiomyocyte Mechanics and Calcium Dynamics by Affecting Phospholamban Phosphorylation and ATP Production 132
Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism 126
ATTIVITÀ CHEMIO PREVENTIVA DELLE CATECHINE DEL TÈ VERDE NEL CANCRO DELLA PROSTATA 123
Acute hyperbaric oxygen (HBO) treatment rapidly upregulate ODC and downregulate SSAT in the rat heart, boosting polyamine tissue concentration: evidence for a protective role of natural polyamines in heart failure as naturally occurring in vivo antioxidants? 103
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism 100
Rat cardiac polyamine metabolism response to HBO (hyperbaric oxygen)depends on intensity of treatment 94
A novel transgenic model for prostate cancer displays the tumor-suppressor activity of Clusterin 92
Polyphenon E®, a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis 89
Clusterin 89
Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development 88
CLU expression negatively modulates prostate cancer progression by inhibiting NF-kB activity 88
The down-regulation of clusterin expression enhances the αsynuclein aggregation process 88
Lemur tyrosine kinases and prostate cancer: A literature review 86
Chronic administration of green tea extract to TRAMP mice induces the collapse ofGolgi apparatus in prostate secretory cells and results in alterations of proteinpost-translational processing. 86
Changes in prostate polyamine metabolism by green tea catechins in autochtonous mouse model of prostate cancer (TRAMP mice) 85
AA Sequencing, Glycosylation and Phosphorylation Site Characterization of Human Serum Clusterin using Liquid Chromatography-High Resolution Mass Spectrometry 85
Apoptosi: ruolo fisiologico della morte cellulare 84
Effects of CLU over-expression on NF-kB target genes involved in invasion mechanims: preliminary results 84
Molecular targets of epigallocatechin—gallate (EGCG): A special focus on signal transduction and cancer 84
Green tea catechins for prostate cancer prevention: Present achievements and future challenges 84
Age-dependent expression of sulphated glycoprotein-2 (SGP-2) transcript in the ventral prostate of rats 82
MOLECULAR MECHANISM OF ACTION OF POLYPHENON E, A GREEN TEA EXTRACT, IN BENIGN AND TUMORIGENIC PROSTATE EPITHELIAL CELLS 82
Clinical relevance of green tea catechins on prostate cancer progression in “high risk” men in combination with molecular profiling of catechin-resistant tumors” 81
Protezione del miocardio ischemico: protezione del miocardio mediante attivita' fisica ed ossigeno iperbarico; valutazione dello stress metabolico, del quadro ossidativo e ormonale 80
Chemoprevention of human prostate cancer by green tea catechins: two years later, a follow-up update 79
Changes in rat SOD activity localization following HBO treatment 77
Clusterin is epigenetically repressed in human prostate cancer cells 77
N-Myc-mediated epigenetic reprogramming in advanced prostate cancer: personalized medicine and quality of biological samples 77
Distinct promoters, subjected to epigenetic regulation, drive the expression of two clusterin mRNAs in prostate cancer cells 77
Chemoprevention of human prostate cancer (PCa) by oral administration of green tea catechins (GTCs) in high grade pin (HGPIN) subjects: a preliminary report from a 1 year proof of principle study 76
Chemoprevention of human prostate cancer by oral administration of green tea catechins (GTCs) in high grade PIN subjects: a preliminary report from a 1 year proof of principle study 75
B-MYB is hypophosphorylated and resistant to degradation in neuroblastoma: Implications for cell survival 74
Clusterin as possible biomarker of response to treatment of prostate cancer cells with Polyphenon E 73
Roles of Autophagy Induced by Natural Compounds in Prostate Cancer 71
Chemoprevention of Human Prostate Cancer by Oral Administration of Green Tea Catechins (GTCs) in High Grade PIN Volunteers: a Preliminary Report from a 1 Year Proof-of-Principle Study 70
CLUSTERIN IS EPIGENETICALLY REPRESSED IN HUMAN PROSTATE CANCER CELLS 70
Molecular targets of (-)-Epigallocatechin-3-gallate (EGCG): Specificity and interaction with membrane lipid rafts 70
Le catechine estratte dal tè verde per la prevenzione del tumore della prostata 69
A New transgenic model for prostate cancer and the role of CLU in tumorigenesis 69
Deciphering the role of the molecular chaperone clusterin on α-synuclein aggregation. 69
Clusterin (CLU): From one gene and two transcripts to many proteins 67
Clusterin is a short half-life, poly-ubiquitinated protein which controls the fate of prostate cancer cells 67
Chronic Administration of Green Tea Extracts in TRAMP Mice Reduces the Activity of the Secretory Pathway Causing an Imbalance of the Protein Trafficking 67
The new anti-oncogene clusterin and the molecular profiling of prostate cancer progression and prognosis 66
Clusterin: an “enigmatic” protein that turns to a novel tumour-suppressor gene 66
EGCG antagonizes Bortezomib-, but not MG132-induced cell death in prostate cancer cells 66
Aspects of protein biosynthesis in hypertrophic growth of rat heart 65
Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse 65
Clusterin (CLU) and lung cancer 65
A novel gene signature for molecular diagnosis of human prostate cancer by RT-qPCR. 65
Chemoprevention of human prostate cancer by oral administration of green tea catechins 65
Increased levels of clusterin mRNA in the ventral prostate of the aging rat are associated to increases in cuboidal (atrophic) cell population and not to changes in apoptotic activity 64
Identification of an androgen-repressed mRNA in rat ventral prostate as coding for Sulphated Glycoprotein 2 by cDNA cloning and sequence analysis 64
Clusterin (CLU) and prostate cancer 64
Apoptotic activity and levels of SGP-2 (clusterin) mRNA in the ventral prostate of the aging ra 64
A new transgenic model for prostate cancer (TRAMP/CluKO) and the role of CLU in tumorigenesis 64
Successful prediction of prostate cancer recurrence by gene profiling in combination with clinical data: a 5 years follow-up study 63
Clusterin (SGP-2) gene expression is cell cycle dependent in normal human dermal fibroblasts 63
Upregulation of Clusterin in Prostate and DNA Damage in Spermatozoa from Bisphenol A-Treated Rats, and Formation of DNA Adducts in Cultured Human Prostatic Cells 63
The role of clusterin on alpha-synuclein aggregation in an “in vitro” model of Parkinson disease 63
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 63
Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kda nuclear isoform of clusterin 62
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism 62
Clusterin (SGP-2) transient overexpression decreases proliferation rate of sv40-immortalised human prostate epithelial cells by slowing down cell cycle progression 62
Inhibitory Effects of Green Tea Catechins on Prostate Cancer progression 61
Clusterin is a short half-life, poly-ubiquitinated protein which controls the fate of prostate cancer cells 60
Role of Clusterin in normal or tumoral bronchial human cells exposed to cigarette smoke 60
Influence of hyperbaric oxygen (HBO) on rat cardiac polyamine metabolism. 59
Effects of Clusterin knock down on prostate cancer progression in the tramp model 59
Human Prostate Cancer Prevention by Green Tea Catechins:Clinical Trial and Putative Molecular Mechanism of Action 59
Inhibition of spontaneous and androgen-induced prostate growth by a non hypercalcemic calcitriol analogue 58
Anti-tumor activity of Green Tea Catechins against human prostate cancer: the clinical trial 58
Variazioni del profilo e della funzionalità polisomale di branzino (Dicentrarchus labrax) in condizioni di ridotto accrescimento 58
Clinical relevance of the inhibitory effect of Green Tea Catechins (GTCs) on prostate cancer progression in combination with molecular profiling of catechin-resistant tumors: an integrated view 58
Regional increases in ornithine decarboxylase mRNA levels in the rat brain after partial mesodiencephalic hemitransection as revealed by in situ hybridization histochemistry 58
Coordinate changes of polyamine metabolism regulatory proteins during the cell cycle of normal human dermal fibroblasts 57
Anticancer activity of green tea polyphenols in prostate gland 57
The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin overexpression 57
Determination of the level of expression of ODC, AdoMetDC, OAZ and SSAT for molecular classification of Green Tea Catechins-sensitive and –resistant Prostate Cancer in the TRAMP mice model by q-PCR gene profiling 57
Ca2+ depletion caused nuclear translocation of a 45kda death-isoform of clusterin and anoikis induction in prostate cells 57
Molecular classification of Green Tea Catechins-sensitive and -resistant prostate cancer in the TRAMP mice model by quantitative real-time PCR gene profiling 56
Development of a green fluorescent reporter for the bio-assay of anti-cancer drugs with anti-oxidant activity 56
Molecular diagnosis of human prostate cancer (CaP) by RT-qPCR determination of gene expression signature 56
Epigenetic regulation of clusterin transcriptional variants in normal, immortalized and cancerous human cell lines 55
Espressione in forma ricombinante di differenti forme di clusterina 54
Changes in the levels of the mRNAs coding for SGP-2 (clusterin), ornithine decarboxylase and gliceraldeyde-3-phosphate drogenase in the testis and ventral prostate of the aging rat 54
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism 54
Inhibition of prostate cell growth by BXL-628, a calcitriol analogue selected for a phase II clinical trial in BPH patients 53
Molecular mechanisms of the antimetastatic activity of nuclear clusterin in prostate cancer cells 53
Variazioni reciproche nella concentrazione degli RNAm della ornitina decarbossilasi e dell'SGP-2: possibile ruolo nel controllo dell'omeostasi cellulare 52
Clusterin gene expression as a novel biomarker of response to chemoprevention with GTE in humans 52
The Twin Sample™ (TS) needle: a novel device for prostate mapping which allows pathological analyses and molecular studies on the same tissue specimen 52
Estrogens, but not androgens, regulate expression and functional activity of oxytocin receptor in rabbit epididymis 51
Development of a green fluorescent reporter plasmid for the bio-assay of anti-oxidant compounds 51
The Potential of Epigallocatechin Gallate (EGCG) in Targeting Autophagy for Cancer Treatment: A Narrative Review 51
In Vivo Treatment with a Standardized Green Tea Extract Restores Cardiomyocyte Contractility in Diabetic Rats by Improving Mitochondrial Function through SIRT1 Activation 50
Clusterin is epigenetically repressed in human prostate cancer. 50
Anti-tumor activity of polyphenols against prostate cancer 50
Totale 7.099
Categoria #
all - tutte 35.054
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.054


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019209 0 0 0 0 0 0 0 0 0 16 187 6
2019/20202.995 440 381 177 98 269 378 392 66 231 320 55 188
2020/20211.708 5 184 131 19 225 57 212 45 303 51 449 27
2021/20221.143 22 60 8 29 43 30 153 172 57 100 146 323
2022/20233.236 377 290 228 263 232 363 22 196 1.125 9 95 36
2023/2024856 88 99 44 27 166 251 66 55 24 36 0 0
Totale 11.392