IRIS
BETTUZZI, Saverio
 Distribuzione geografica
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Continente #
NA - Nord America 7.636
AS - Asia 6.325
EU - Europa 5.074
SA - Sud America 1.152
AF - Africa 336
Continente sconosciuto - Info sul continente non disponibili 15
OC - Oceania 15
Totale 20.553
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Nazione #
US - Stati Uniti d'America 7.401
SG - Singapore 2.538
CN - Cina 2.134
IE - Irlanda 962
BR - Brasile 898
UA - Ucraina 750
FI - Finlandia 658
SE - Svezia 641
IT - Italia 639
DE - Germania 531
HK - Hong Kong 499
VN - Vietnam 495
NL - Olanda 243
ZA - Sudafrica 229
CA - Canada 186
TR - Turchia 155
AT - Austria 138
FR - Francia 125
GB - Regno Unito 122
AR - Argentina 104
RU - Federazione Russa 99
IN - India 93
BD - Bangladesh 87
IR - Iran 70
KR - Corea 65
EC - Ecuador 48
BE - Belgio 38
CI - Costa d'Avorio 33
ID - Indonesia 30
IQ - Iraq 30
MX - Messico 29
JP - Giappone 27
VE - Venezuela 25
CO - Colombia 24
PL - Polonia 24
ES - Italia 19
UZ - Uzbekistan 19
MA - Marocco 18
CZ - Repubblica Ceca 17
EG - Egitto 15
PY - Paraguay 14
CL - Cile 13
EU - Europa 12
PE - Perù 12
AE - Emirati Arabi Uniti 11
AU - Australia 11
KE - Kenya 11
LT - Lituania 11
SK - Slovacchia (Repubblica Slovacca) 11
TN - Tunisia 10
UY - Uruguay 10
IL - Israele 8
NP - Nepal 8
AZ - Azerbaigian 7
PK - Pakistan 7
RO - Romania 7
BG - Bulgaria 5
CH - Svizzera 5
DO - Repubblica Dominicana 5
JO - Giordania 5
SA - Arabia Saudita 5
BO - Bolivia 4
DZ - Algeria 4
KG - Kirghizistan 4
NZ - Nuova Zelanda 4
PT - Portogallo 4
SN - Senegal 4
TT - Trinidad e Tobago 4
AL - Albania 3
CR - Costa Rica 3
DK - Danimarca 3
HU - Ungheria 3
KW - Kuwait 3
KZ - Kazakistan 3
LB - Libano 3
LU - Lussemburgo 3
LV - Lettonia 3
OM - Oman 3
PA - Panama 3
XK - ???statistics.table.value.countryCode.XK??? 3
AM - Armenia 2
BH - Bahrain 2
BI - Burundi 2
BY - Bielorussia 2
EE - Estonia 2
GE - Georgia 2
HR - Croazia 2
JM - Giamaica 2
LA - Repubblica Popolare Democratica del Laos 2
MR - Mauritania 2
MY - Malesia 2
NG - Nigeria 2
PH - Filippine 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BW - Botswana 1
ET - Etiopia 1
GA - Gabon 1
HN - Honduras 1
LY - Libia 1
Totale 20.543
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Città #
Singapore 1.106
Dublin 961
Jacksonville 867
Chandler 833
Ashburn 784
Dearborn 509
Hong Kong 498
Santa Clara 484
Beijing 475
Boardman 279
Nanjing 272
Dallas 251
Ann Arbor 248
San Mateo 224
Johannesburg 215
Princeton 211
Ho Chi Minh City 174
Parma 170
Toronto 135
Shanghai 127
Vienna 124
Los Angeles 121
Wilmington 116
Hefei 113
Izmir 113
Nanchang 96
Shenyang 96
Hanoi 88
São Paulo 82
Jinan 81
Munich 81
Helsinki 77
Hebei 73
Moscow 68
Leawood 67
New York 67
Des Moines 64
Kunming 61
Seoul 60
Tianjin 58
Changsha 56
Guangzhou 50
Jiaxing 49
Buffalo 45
Marseille 41
Columbus 38
Houston 38
Brussels 37
Augusta 36
Turku 36
Seattle 34
Abidjan 33
Council Bluffs 32
Milan 32
Fremont 31
Ardabil 30
Haikou 30
The Dalles 30
Woodbridge 29
Brooklyn 28
Rio de Janeiro 27
Rome 25
Tokyo 25
Zhengzhou 25
Haiphong 23
Kocaeli 23
London 23
Chicago 22
Nuremberg 22
Da Nang 21
Norwalk 21
Warsaw 21
Ardea 20
Biên Hòa 20
Montreal 20
Hangzhou 19
Monmouth Junction 19
Belo Horizonte 18
Curitiba 18
Tashkent 18
Bologna 17
Mumbai 17
Quito 17
Redondo Beach 16
Stockholm 16
Taiyuan 16
Chengdu 15
Denver 15
Falls Church 15
Grafing 15
Modena 15
Ninh Bình 15
Porto Alegre 15
Atlanta 14
Dong Ket 14
Phoenix 14
Chennai 13
Guayaquil 13
Hải Dương 13
Jakarta 13
Totale 11.992
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Nome #
Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development 438
Effects of standardized green tea extract and its main component, EGCG, on mitochondrial function and contractile performance of healthy rat cardiomyocytes 241
Flavonoids as epigenetic modulators for prostate cancer prevention 225
Clusterin Silencing in Prostate Cancer Induces Matrix Metalloproteinases by an NF-κB-Dependent Mechanism 208
Long-Term Oral Administration of Theaphenon-E Improves Cardiomyocyte Mechanics and Calcium Dynamics by Affecting Phospholamban Phosphorylation and ATP Production 194
ATTIVITÀ CHEMIO PREVENTIVA DELLE CATECHINE DEL TÈ VERDE NEL CANCRO DELLA PROSTATA 192
In Vivo Treatment with a Standardized Green Tea Extract Restores Cardiomyocyte Contractility in Diabetic Rats by Improving Mitochondrial Function through SIRT1 Activation 176
The down-regulation of clusterin expression enhances the αsynuclein aggregation process 171
Lemur tyrosine kinases and prostate cancer: A literature review 171
A novel transgenic model for prostate cancer displays the tumor-suppressor activity of Clusterin 168
Acute hyperbaric oxygen (HBO) treatment rapidly upregulate ODC and downregulate SSAT in the rat heart, boosting polyamine tissue concentration: evidence for a protective role of natural polyamines in heart failure as naturally occurring in vivo antioxidants? 164
AA Sequencing, Glycosylation and Phosphorylation Site Characterization of Human Serum Clusterin using Liquid Chromatography-High Resolution Mass Spectrometry 164
Epigenetic regulation of clusterin transcriptional variants in normal, immortalized and cancerous human cell lines 161
CLU expression negatively modulates prostate cancer progression by inhibiting NF-kB activity 159
Clusterin 159
Rat cardiac polyamine metabolism response to HBO (hyperbaric oxygen)depends on intensity of treatment 156
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism 155
The Potential of Epigallocatechin Gallate (EGCG) in Targeting Autophagy for Cancer Treatment: A Narrative Review 154
Distinct promoters, subjected to epigenetic regulation, drive the expression of two clusterin mRNAs in prostate cancer cells 151
Apoptosi: ruolo fisiologico della morte cellulare 150
Changes in prostate polyamine metabolism by green tea catechins in autochtonous mouse model of prostate cancer (TRAMP mice) 148
Molecular targets of epigallocatechin—gallate (EGCG): A special focus on signal transduction and cancer 145
MOLECULAR MECHANISM OF ACTION OF POLYPHENON E, A GREEN TEA EXTRACT, IN BENIGN AND TUMORIGENIC PROSTATE EPITHELIAL CELLS 144
Chronic administration of green tea extract to TRAMP mice induces the collapse ofGolgi apparatus in prostate secretory cells and results in alterations of proteinpost-translational processing. 144
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) 144
Age-dependent expression of sulphated glycoprotein-2 (SGP-2) transcript in the ventral prostate of rats 139
Polyphenon E®, a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis 139
Green tea catechins for prostate cancer prevention: Present achievements and future challenges 137
Chemoprevention of human prostate cancer by oral administration of green tea catechins (GTCs) in high grade PIN subjects: a preliminary report from a 1 year proof of principle study 136
Changes in rat SOD activity localization following HBO treatment 135
Effects of CLU over-expression on NF-kB target genes involved in invasion mechanims: preliminary results 134
Upregulation of Clusterin in Prostate and DNA Damage in Spermatozoa from Bisphenol A-Treated Rats, and Formation of DNA Adducts in Cultured Human Prostatic Cells 133
Protezione del miocardio ischemico: protezione del miocardio mediante attivita' fisica ed ossigeno iperbarico; valutazione dello stress metabolico, del quadro ossidativo e ormonale 133
Effects of Clusterin knock down on prostate cancer progression in the tramp model 132
A novel gene signature for molecular diagnosis of human prostate cancer by RT-qPCR. 131
Clinical relevance of green tea catechins on prostate cancer progression in “high risk” men in combination with molecular profiling of catechin-resistant tumors” 130
A New transgenic model for prostate cancer and the role of CLU in tumorigenesis 130
Roles of Autophagy Induced by Natural Compounds in Prostate Cancer 130
Clusterin as possible biomarker of response to treatment of prostate cancer cells with Polyphenon E 130
CLUSTERIN IS EPIGENETICALLY REPRESSED IN HUMAN PROSTATE CANCER CELLS 129
The role of clusterin on alpha-synuclein aggregation in an “in vitro” model of Parkinson disease 129
B-MYB is hypophosphorylated and resistant to degradation in neuroblastoma: Implications for cell survival 129
Molecular targets of (-)-Epigallocatechin-3-gallate (EGCG): Specificity and interaction with membrane lipid rafts 128
Aspects of protein biosynthesis in hypertrophic growth of rat heart 127
Chemoprevention of human prostate cancer by green tea catechins: two years later, a follow-up update 127
Clusterin is epigenetically repressed in human prostate cancer cells 126
Chemoprevention of human prostate cancer (PCa) by oral administration of green tea catechins (GTCs) in high grade pin (HGPIN) subjects: a preliminary report from a 1 year proof of principle study 123
Chronic Administration of Green Tea Extracts in TRAMP Mice Reduces the Activity of the Secretory Pathway Causing an Imbalance of the Protein Trafficking 123
Deciphering the role of the molecular chaperone clusterin on α-synuclein aggregation. 123
EGCG antagonizes Bortezomib-, but not MG132-induced cell death in prostate cancer cells 122
Chemoprevention of Human Prostate Cancer by Oral Administration of Green Tea Catechins (GTCs) in High Grade PIN Volunteers: a Preliminary Report from a 1 Year Proof-of-Principle Study 120
A new transgenic model for prostate cancer (TRAMP/CluKO) and the role of CLU in tumorigenesis 120
Anti-tumor activity of Green Tea Catechins against human prostate cancer: the clinical trial 119
Ca2+ depletion caused nuclear translocation of a 45kda death-isoform of clusterin and anoikis induction in prostate cells 119
Apoptotic activity and levels of SGP-2 (clusterin) mRNA in the ventral prostate of the aging ra 119
Clusterin (CLU): From one gene and two transcripts to many proteins 116
Clusterin (CLU) and prostate cancer 116
Chemoprevention of human prostate cancer by oral administration of green tea catechins 115
Le catechine estratte dal tè verde per la prevenzione del tumore della prostata 114
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism 114
Anticancer activity of green tea polyphenols in prostate gland 113
N-Myc-mediated epigenetic reprogramming in advanced prostate cancer: personalized medicine and quality of biological samples 113
Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kda nuclear isoform of clusterin 112
Androgen responsiveness and intrarenal localization of transcripts coding for the enzymes of polyamine metabolism in the mouse 111
Clusterin gene expression as a novel biomarker of response to chemoprevention with GTE in humans 111
Influence of hyperbaric oxygen (HBO) on rat cardiac polyamine metabolism. 110
Clusterin (CLU) and lung cancer 110
Clinical relevance of the inhibitory effect of Green Tea Catechins (GTCs) on prostate cancer progression in combination with molecular profiling of catechin-resistant tumors: an integrated view 109
Determination of the level of expression of ODC, AdoMetDC, OAZ and SSAT for molecular classification of Green Tea Catechins-sensitive and –resistant Prostate Cancer in the TRAMP mice model by q-PCR gene profiling 109
EGCG antagonizes Bortezomib cytotoxicity in prostate cancer cells by an autophagic mechanism 109
Clusterin is a short half-life, poly-ubiquitinated protein which controls the fate of prostate cancer cells 104
Clusterin is epigenetically repressed in human prostate cancer. 100
Anti-tumor activity of polyphenols against prostate cancer 100
Successful prediction of prostate cancer recurrence by gene profiling in combination with clinical data: a 5 years follow-up study 99
Identification of an androgen-repressed mRNA in rat ventral prostate as coding for Sulphated Glycoprotein 2 by cDNA cloning and sequence analysis 99
Editorial: Challenges in the prevention of prostate cancer 97
Clusterin (SGP-2) gene expression is cell cycle dependent in normal human dermal fibroblasts 96
Clusterin is a short half-life, poly-ubiquitinated protein which controls the fate of prostate cancer cells 96
Variazioni del profilo e della funzionalità polisomale di branzino (Dicentrarchus labrax) in condizioni di ridotto accrescimento 96
Increased levels of clusterin mRNA in the ventral prostate of the aging rat are associated to increases in cuboidal (atrophic) cell population and not to changes in apoptotic activity 95
Clusterin (SGP-2) transient overexpression decreases proliferation rate of sv40-immortalised human prostate epithelial cells by slowing down cell cycle progression 95
Identification and characterization of a novel promoter of the CLU gene which drives the expression of a rare CLU mRNA variant in PCa cells following administration of epigenetic drugs. 95
The new anti-oncogene clusterin and the molecular profiling of prostate cancer progression and prognosis 94
The tumor-suppressor activity of Clusterin (CLU) is fully displayed in a novel transgenic model for prostate cancer: the TRAMP/CluKO mice model 94
Clusterin Mediated Apoptosis is Regulated by APC and is P21 Dependent but P53 Independent 93
Coordinate changes of polyamine metabolism regulatory proteins during the cell cycle of normal human dermal fibroblasts 93
Green tea catechins for chemoprevention of human prostate cancer: from the bench (basic research) to the bedside (result of the clinical trial) 93
Inhibitory Effects of Green Tea Catechins on Prostate Cancer progression 92
Human Prostate Cancer Prevention by Green Tea Catechins:Clinical Trial and Putative Molecular Mechanism of Action 92
Regional increases in ornithine decarboxylase mRNA levels in the rat brain after partial mesodiencephalic hemitransection as revealed by in situ hybridization histochemistry 92
SGP-2, apoptosis and aging 91
Molecular mechanisms of the antimetastatic activity of nuclear clusterin in prostate cancer cells 91
Inhibition of spontaneous and androgen-induced prostate growth by a non hypercalcemic calcitriol analogue 90
Development of a green fluorescent reporter for the bio-assay of anti-cancer drugs with anti-oxidant activity 90
Studies on the relationship between cell proliferation and cell death: apposite patterns of SGP-2 and ornithine decarboxylase mRNA accumulation in PHA-stimulated human limphocytes 90
Role of Clusterin in normal or tumoral bronchial human cells exposed to cigarette smoke 89
Il tè verde nella chemoprevenzione oncologica 89
The Clusterin Paradigm in Prostate and Breast Carcinogenesis 89
The Twin Sample™ (TS) needle: a novel device for prostate mapping which allows pathological analyses and molecular studies on the same tissue specimen 88
The chemopreventive action of catechins in the TRAMP mouse model of prostate carcinogenesis is accompanied by clusterin overexpression 88
Totale 12.826
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Categoria #
all - tutte 71.317
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 71.317
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.144 0 0 0 0 0 57 212 45 303 51 449 27
2021/20221.143 22 60 8 29 43 30 153 172 57 100 146 323
2022/20233.236 377 290 228 263 232 363 22 196 1.125 9 95 36
2023/20241.097 88 99 44 27 166 251 66 55 24 44 85 148
2024/20254.160 82 265 269 208 374 410 105 111 572 524 498 742
2025/20264.877 760 897 915 967 1.194 144 0 0 0 0 0 0
Totale 20.670