TOSCANI, Denise
TOSCANI, Denise
Dipartimento di Medicina e Chirurgia
(2S,4R)-4-fluoroglutamine is converted into (2S,4R)-4-fluoroglutamate by glutaminase activity and may be exploited as a PET tracer in glutamine-addicted cancers
2021-01-01 Chiu, Martina; Toscani, Denise; Ferlenghi, Francesca; Taurino, Giuseppe; Sartori, Andrea; Vacondio, Federica; Zanardi, Franca; Giuliani, Nicola; Bussolati, Ovidio
[18F](2S,4R)-4-Fluoroglutamine as a New Positron Emission Tomography Tracer in Myeloma
2021-01-01 Valtorta, S.; Toscani, D.; Chiu, M.; Sartori, A.; Coliva, A.; Brevi, A.; Taurino, G.; Grioni, M.; Ruffini, L.; Vacondio, F.; Zanardi, F.; Bellone, M.; Moresco, R. M.; Bussolati, O.; Giuliani, N.
A personalized molecular approach in multiple myeloma: the possible use of RAF/RAS/MEK/ERK and BCL-2 inhibitors
2022-01-01 Raimondi, Vincenzo; Iannozzi, Nicolas Thomas; Burroughs-Garcìa, Jessica; Toscani, Denise; Storti, Paola; Giuliani, Nicola
Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates with Progression of Human Myeloma.
2016-01-01 Horenstein, Al; Quarona, V; Toscani, Denise; Costa, Federica; Chillemi, A; Pistoia, V; Giuliani, Nicola; Malavasi, F.
ADENOSINE IN THE MYELOMA BONE MARROW NICHE: IMMUNE CHECKPOINT AND KEY PLAYER IN DISEASE PROGRESSION
2017-01-01 Horenstein, A; Chillemi, A; Quarona, V; Costa, Federica; Toscani, Denise; Morandi, F; Marimpietro, D; Giuliani, Nicola; Malavasi, F.
Bone marrow CX3CL1/Fractalkine is a new player of the pro-angiogenic microenvironment in multiple myeloma patients
2019-01-01 Marchica, Valentina; Toscani, Denise; Corcione, Anna; Bolzoni, Marina; Storti, Paola; Vescovini, Rosanna; Ferretti, Elisa; Palma, Benedetta Dalla; Vicario, Emanuela; Accardi, Fabrizio; Mancini, Cristina; Martella, Eugenia; Ribatti, Domenico; Vacca, Angelo; Pistoia, Vito; Giuliani, Nicola
Bone marrow Dikkopf-1 levels are a new independent risk factor for progression in patients with smouldering myeloma
2018-01-01 Dalla Palma, Benedetta; Marchica, Valentina; Pedrazzoni, Mario; Accardi, Fabrizio; Notarfranchi, Laura; Goldoni, Matteo; De Luca, Federica; Costa, Federica; Storti, Paola; Toscani, Denise; Sammarelli, Gabriella; Bonomini, Sabrina; Aversa, Franco; Giuliani, Nicola
Bone marrow stromal cell-fueled multiple myeloma growth and osteoclastogenesis are sustained by protein kinase CK2
2014-01-01 Manni, S; Toscani, Denise; Mandato, E; Brancalion, A; Quotti Tubi, L; Macaccaro, P; Cabrelle, A; Adami, F; Zambello, R; Gurrieri, C; Semenzato, G; Giuliani, Nicola; Piazza, F.
Bortezomib improves bone integrity in multiple myeloma patients by blocking osteocyte death and autophagy
2013-01-01 Toscani, Denise; Dalla Palma, B; Palumbo, C; Ferretti, M; Bolzoni, Marina; Mancini, C; Martella, E; Aversa, Franco; Giuliani, Nicola
Bovine pestivirus is a new alternative virus for multiple myeloma oncolytic virotherapy
2020-01-01 Marchica, Valentina; Franceschi, Valentina; Vescovini, Rosanna; Storti, Paola; Vicario, Emanuela; Toscani, Denise; Zorzoli, Alessia; Airoldi, Irma; Dalla Palma, Benedetta; Campanini, Nicoletta; Martella, Eugenia; Mancini, Cristina; Costa, Federica; Donofrio, Gaetano; Giuliani, Nicola
CD14+CD16+ monocytes are involved in daratumumab-mediated myeloma cells killing and in anti-CD47 therapeutic strategy
2020-01-01 Storti, P.; Vescovini, R.; Costa, F.; Marchica, V.; Toscani, D.; Dalla Palma, B.; Craviotto, L.; Malavasi, F.; Giuliani, N.
CK2 Kinase Inhibitors Display Anti-Myeloma Effects and Antagonize Osteoclast Activity in Models of Multiple Myeloma Bone Marrow Microenvironment
2012-01-01 Manni, S; Toscani, Denise; Colpo, A; Brancalion, A; Zaffino, F; Quotti Tubi, F; Semenzato, G; Giuliani, Nicola; Piazza, F.
Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target
2016-01-01 Bolzoni, Marina; Chiu, Martina; Accardi, Fabrizio; Vescovini, Rosanna; Airoldi, Irma; Storti, Paola; Todoerti, Katia; Agnelli, Luca; Missale, Gabriele; Andreoli, Roberta; Bianchi, Massimiliano; Allegri, Manfredi; Barilli, Amelia; Nicolini, Francesco; Cavalli, Albertina; Costa, Federica; Marchica, Valentina; Toscani, Denise; Mancini, Cristina; Martella, Eugenia; Dall'Asta, Valeria; Donofrio, Gaetano; Aversa, Franco; Bussolati, Ovidio; Giuliani, Nicola
DEPENDENCE ON GLUTAMINE UPTAKE OF MYELOMA CELLS DELINEATES A NEW ATTRACTIVE THERAPEUTIC STRATEGY
2016-01-01 Bolzoni, Marina; Chiu, Martina; Accardi, F; Storti, Paola; Airoldi, I; Todoerti, K; Agnelli, L; Missale, G; Andreoli, Roberta; Bianchi, Massimiliano; Allegri, Manfredi; Barilli, Amelia; Toscani, Denise; Costa, Federica; Marchica, Valentina; Aversa, Franco; Bussolati, Ovidio; Giuliani, Nicola
EXPRESSION OF CD38 AND ECTOENZYMES OF THE ADENOSINERGIC PATHWAYS IN MYELOMA BONE NICHE: A RATIONAL BASIS FOR THE USE OF DARATUMUMAB TO TARGET OSTEOCLAST FORMATION IN MULTIPLE MYELOMA
2017-01-01 Costa, Federica; Toscani, Denise; Chillemi, A; Quarona, V; Bolzoni, Marina; Marchica, Valentina; Vescovini, Rosanna; Mancini, C; Martella, E; Campanini, Nicoletta; Schifano, C; Bonomini, S; Accardi, Fabrizio; Horenstein, Al; Aversa, Franco; Malavasi, F; Giuliani, Nicola
Expression of CD38 in myeloma bone niche: A rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation
2017-01-01 Costa, Federica; Toscani, Denise; Chillemi, Antonella; Quarona, Valeria; Bolzoni, Marina; Marchica, Valentina; Vescovini, Rosanna; Mancini, Cristina; Martella, Eugenia; Campanini, Nicoletta; Schifano, Chiara; Bonomini, Sabrina; Accardi, Fabrizio; Horenstein, Alberto L.; Aversa, Franco; Malavasi, Fabio; Giuliani, Nicola
Expression Profile of CD38 and Related Ectoenzymes in Myeloma Bone Niche: A Rational Basis for the Use of Daratumumab to Inhibit Osteoclast Formation and Activity
2015-01-01 Toscani, Denise; Bolzoni, Marina; Costa, Federica; Quarona, Valeria; Marchica, Valentina; Mancini, Cristina; Martella, Eugenia; Bonomini, Sabrina; Storti, Paola; Chillemi, Antonella; Accardi, Fabrizio; Dalla Palma, Benedetta; Craviotto, Luisa; Malavasi, Fabio; Aversa, Franco; Giuliani, Nicola
Generation and Characterization of Microvesicles after Daratumumab Interaction with Myeloma Cells
2015-01-01 Chillemi, Antonella; Quarona, Valeria; Zito, Andrea; Morandi, Fabio; Marimpietri, Danilo; Cuccioloni, Massimiliano; Robert, Oldham J.; Mark, Cragg S.; Bolzoni, Marina; Toscani, Denise; Pistoia, Vito; Giuliani, Nicola; Horenstein, Alberto L; Sasser, Kate; Malavasi, Fabio
Gfi1 Transcription Factor Is a Pro-Survival Molecule in Multiple Myeloma Cells
2016-01-01 Toscani, Denise; Cheolkyu, Park; Fengming, Wang; Judith, Anderson; Giuliani, Nicola; David Roodman, G.; Daniela Nicoleta, Petrusca
Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis
2018-01-01 Petrusca, Daniela N.; Toscani, Denise; Wang, Feng-Ming; Park, Cheolkyu; Crean, Colin D.; Anderson, Judith L.; Marino, Silvia; Mohammad, Khalid S.; Zhou, Dan; Silbermann, Rebecca; Sun, Quanhong; Kurihara, Noriyoshi; Galson, Deborah L.; Giuliani, Nicola; Roodman, G. David
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| (2S,4R)-4-fluoroglutamine is converted into (2S,4R)-4-fluoroglutamate by glutaminase activity and may be exploited as a PET tracer in glutamine-addicted cancers | 1-gen-2021 | Chiu, Martina; Toscani, Denise; Ferlenghi, Francesca; Taurino, Giuseppe; Sartori, Andrea; Vacondio, Federica; Zanardi, Franca; Giuliani, Nicola; Bussolati, Ovidio | |
| [18F](2S,4R)-4-Fluoroglutamine as a New Positron Emission Tomography Tracer in Myeloma | 1-gen-2021 | Valtorta, S.; Toscani, D.; Chiu, M.; Sartori, A.; Coliva, A.; Brevi, A.; Taurino, G.; Grioni, M.; Ruffini, L.; Vacondio, F.; Zanardi, F.; Bellone, M.; Moresco, R. M.; Bussolati, O.; Giuliani, N. | |
| A personalized molecular approach in multiple myeloma: the possible use of RAF/RAS/MEK/ERK and BCL-2 inhibitors | 1-gen-2022 | Raimondi, Vincenzo; Iannozzi, Nicolas Thomas; Burroughs-Garcìa, Jessica; Toscani, Denise; Storti, Paola; Giuliani, Nicola | |
| Adenosine Generated in the Bone Marrow Niche Through a CD38-Mediated Pathway Correlates with Progression of Human Myeloma. | 1-gen-2016 | Horenstein, Al; Quarona, V; Toscani, Denise; Costa, Federica; Chillemi, A; Pistoia, V; Giuliani, Nicola; Malavasi, F. | |
| ADENOSINE IN THE MYELOMA BONE MARROW NICHE: IMMUNE CHECKPOINT AND KEY PLAYER IN DISEASE PROGRESSION | 1-gen-2017 | Horenstein, A; Chillemi, A; Quarona, V; Costa, Federica; Toscani, Denise; Morandi, F; Marimpietro, D; Giuliani, Nicola; Malavasi, F. | |
| Bone marrow CX3CL1/Fractalkine is a new player of the pro-angiogenic microenvironment in multiple myeloma patients | 1-gen-2019 | Marchica, Valentina; Toscani, Denise; Corcione, Anna; Bolzoni, Marina; Storti, Paola; Vescovini, Rosanna; Ferretti, Elisa; Palma, Benedetta Dalla; Vicario, Emanuela; Accardi, Fabrizio; Mancini, Cristina; Martella, Eugenia; Ribatti, Domenico; Vacca, Angelo; Pistoia, Vito; Giuliani, Nicola | |
| Bone marrow Dikkopf-1 levels are a new independent risk factor for progression in patients with smouldering myeloma | 1-gen-2018 | Dalla Palma, Benedetta; Marchica, Valentina; Pedrazzoni, Mario; Accardi, Fabrizio; Notarfranchi, Laura; Goldoni, Matteo; De Luca, Federica; Costa, Federica; Storti, Paola; Toscani, Denise; Sammarelli, Gabriella; Bonomini, Sabrina; Aversa, Franco; Giuliani, Nicola | |
| Bone marrow stromal cell-fueled multiple myeloma growth and osteoclastogenesis are sustained by protein kinase CK2 | 1-gen-2014 | Manni, S; Toscani, Denise; Mandato, E; Brancalion, A; Quotti Tubi, L; Macaccaro, P; Cabrelle, A; Adami, F; Zambello, R; Gurrieri, C; Semenzato, G; Giuliani, Nicola; Piazza, F. | |
| Bortezomib improves bone integrity in multiple myeloma patients by blocking osteocyte death and autophagy | 1-gen-2013 | Toscani, Denise; Dalla Palma, B; Palumbo, C; Ferretti, M; Bolzoni, Marina; Mancini, C; Martella, E; Aversa, Franco; Giuliani, Nicola | |
| Bovine pestivirus is a new alternative virus for multiple myeloma oncolytic virotherapy | 1-gen-2020 | Marchica, Valentina; Franceschi, Valentina; Vescovini, Rosanna; Storti, Paola; Vicario, Emanuela; Toscani, Denise; Zorzoli, Alessia; Airoldi, Irma; Dalla Palma, Benedetta; Campanini, Nicoletta; Martella, Eugenia; Mancini, Cristina; Costa, Federica; Donofrio, Gaetano; Giuliani, Nicola | |
| CD14+CD16+ monocytes are involved in daratumumab-mediated myeloma cells killing and in anti-CD47 therapeutic strategy | 1-gen-2020 | Storti, P.; Vescovini, R.; Costa, F.; Marchica, V.; Toscani, D.; Dalla Palma, B.; Craviotto, L.; Malavasi, F.; Giuliani, N. | |
| CK2 Kinase Inhibitors Display Anti-Myeloma Effects and Antagonize Osteoclast Activity in Models of Multiple Myeloma Bone Marrow Microenvironment | 1-gen-2012 | Manni, S; Toscani, Denise; Colpo, A; Brancalion, A; Zaffino, F; Quotti Tubi, F; Semenzato, G; Giuliani, Nicola; Piazza, F. | |
| Dependence on glutamine uptake and glutamine addiction characterize myeloma cells: a new attractive target | 1-gen-2016 | Bolzoni, Marina; Chiu, Martina; Accardi, Fabrizio; Vescovini, Rosanna; Airoldi, Irma; Storti, Paola; Todoerti, Katia; Agnelli, Luca; Missale, Gabriele; Andreoli, Roberta; Bianchi, Massimiliano; Allegri, Manfredi; Barilli, Amelia; Nicolini, Francesco; Cavalli, Albertina; Costa, Federica; Marchica, Valentina; Toscani, Denise; Mancini, Cristina; Martella, Eugenia; Dall'Asta, Valeria; Donofrio, Gaetano; Aversa, Franco; Bussolati, Ovidio; Giuliani, Nicola | |
| DEPENDENCE ON GLUTAMINE UPTAKE OF MYELOMA CELLS DELINEATES A NEW ATTRACTIVE THERAPEUTIC STRATEGY | 1-gen-2016 | Bolzoni, Marina; Chiu, Martina; Accardi, F; Storti, Paola; Airoldi, I; Todoerti, K; Agnelli, L; Missale, G; Andreoli, Roberta; Bianchi, Massimiliano; Allegri, Manfredi; Barilli, Amelia; Toscani, Denise; Costa, Federica; Marchica, Valentina; Aversa, Franco; Bussolati, Ovidio; Giuliani, Nicola | |
| EXPRESSION OF CD38 AND ECTOENZYMES OF THE ADENOSINERGIC PATHWAYS IN MYELOMA BONE NICHE: A RATIONAL BASIS FOR THE USE OF DARATUMUMAB TO TARGET OSTEOCLAST FORMATION IN MULTIPLE MYELOMA | 1-gen-2017 | Costa, Federica; Toscani, Denise; Chillemi, A; Quarona, V; Bolzoni, Marina; Marchica, Valentina; Vescovini, Rosanna; Mancini, C; Martella, E; Campanini, Nicoletta; Schifano, C; Bonomini, S; Accardi, Fabrizio; Horenstein, Al; Aversa, Franco; Malavasi, F; Giuliani, Nicola | |
| Expression of CD38 in myeloma bone niche: A rational basis for the use of anti-CD38 immunotherapy to inhibit osteoclast formation | 1-gen-2017 | Costa, Federica; Toscani, Denise; Chillemi, Antonella; Quarona, Valeria; Bolzoni, Marina; Marchica, Valentina; Vescovini, Rosanna; Mancini, Cristina; Martella, Eugenia; Campanini, Nicoletta; Schifano, Chiara; Bonomini, Sabrina; Accardi, Fabrizio; Horenstein, Alberto L.; Aversa, Franco; Malavasi, Fabio; Giuliani, Nicola | |
| Expression Profile of CD38 and Related Ectoenzymes in Myeloma Bone Niche: A Rational Basis for the Use of Daratumumab to Inhibit Osteoclast Formation and Activity | 1-gen-2015 | Toscani, Denise; Bolzoni, Marina; Costa, Federica; Quarona, Valeria; Marchica, Valentina; Mancini, Cristina; Martella, Eugenia; Bonomini, Sabrina; Storti, Paola; Chillemi, Antonella; Accardi, Fabrizio; Dalla Palma, Benedetta; Craviotto, Luisa; Malavasi, Fabio; Aversa, Franco; Giuliani, Nicola | |
| Generation and Characterization of Microvesicles after Daratumumab Interaction with Myeloma Cells | 1-gen-2015 | Chillemi, Antonella; Quarona, Valeria; Zito, Andrea; Morandi, Fabio; Marimpietri, Danilo; Cuccioloni, Massimiliano; Robert, Oldham J.; Mark, Cragg S.; Bolzoni, Marina; Toscani, Denise; Pistoia, Vito; Giuliani, Nicola; Horenstein, Alberto L; Sasser, Kate; Malavasi, Fabio | |
| Gfi1 Transcription Factor Is a Pro-Survival Molecule in Multiple Myeloma Cells | 1-gen-2016 | Toscani, Denise; Cheolkyu, Park; Fengming, Wang; Judith, Anderson; Giuliani, Nicola; David Roodman, G.; Daniela Nicoleta, Petrusca | |
| Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis | 1-gen-2018 | Petrusca, Daniela N.; Toscani, Denise; Wang, Feng-Ming; Park, Cheolkyu; Crean, Colin D.; Anderson, Judith L.; Marino, Silvia; Mohammad, Khalid S.; Zhou, Dan; Silbermann, Rebecca; Sun, Quanhong; Kurihara, Noriyoshi; Galson, Deborah L.; Giuliani, Nicola; Roodman, G. David |