Neutral rhodol-based red emitters are shown to efficiently localize in mitochondria, as demonstrated by confocal microscopy and co-localization studies. A simple model is proposed to explain the localization mechanism of neutral molecules. The model takes into account the strong coupling between the molecular dipole moment and the electric field of the inner mitochondrial membrane.Neutral rhodol-based red emitters are shown to efficiently localize in mitochondria, as demonstrated by confocal microscopy and co-localization studies.
Neutral rhodol-based dyes expressing localization in mitochondria / Ferraboschi, I.; Ovčar, J.; Vygranenko, K. V.; Yu, S.; Minervino, A.; Wrzosek, A.; Szewczyk, A.; Rozza, R.; Magistrato, A.; Belfield, K. D.; Gryko, D. T.; Grisanti, L.; Sissa, C.. - In: ORGANIC & BIOMOLECULAR CHEMISTRY. - ISSN 1477-0520. - (2024). [10.1039/d4ob00252k]
Neutral rhodol-based dyes expressing localization in mitochondria
Ferraboschi I.;Belfield K. D.;Grisanti L.
;Sissa C.
2024-01-01
Abstract
Neutral rhodol-based red emitters are shown to efficiently localize in mitochondria, as demonstrated by confocal microscopy and co-localization studies. A simple model is proposed to explain the localization mechanism of neutral molecules. The model takes into account the strong coupling between the molecular dipole moment and the electric field of the inner mitochondrial membrane.Neutral rhodol-based red emitters are shown to efficiently localize in mitochondria, as demonstrated by confocal microscopy and co-localization studies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
