Highly distorted and rigid cone conformers of calix[4]arene have been synthesized by low-valent titanium promoted intra-molecular coupling of aldehydes 1a-d. The reaction outcome strongly depends on the substituents present at the upper rim and reaction time. In all cases examined infra-molecular coupled compounds, having a bridge only two atoms long, were obtained in about 30% yield. © 1995 Elsevier Science Ltd.
Highly distorted Cone calix[4]arenes through intramolecular mc murry coupling reaction / Arduini, A.; Fanni, S.; Pochini, A.; Sicuri, A. R.; Ungaro, R.. - In: TETRAHEDRON. - ISSN 0040-4020. - 51:29(1995), pp. 7951-7958. [10.1016/0040-4020(95)00411-Z]
Highly distorted Cone calix[4]arenes through intramolecular mc murry coupling reaction
Arduini A.;Pochini A.;Ungaro R.
1995-01-01
Abstract
Highly distorted and rigid cone conformers of calix[4]arene have been synthesized by low-valent titanium promoted intra-molecular coupling of aldehydes 1a-d. The reaction outcome strongly depends on the substituents present at the upper rim and reaction time. In all cases examined infra-molecular coupled compounds, having a bridge only two atoms long, were obtained in about 30% yield. © 1995 Elsevier Science Ltd.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
