Objectives: The aim of this study was to determine the prevalence of respiratory virus infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the winter period December 2019 to March 2020, via a tertiary care hospital-based survey in Parma, Northern Italy. Methods: A total of 906 biological samples from the respiratory tract were analysed by both conventional assays (including culture) and molecular assays targeting nucleic acids of SARS-CoV-2 and other respiratory viruses. Results: Overall, 474 samples (52.3%) were positive for at least one virus, with a total of 583 viruses detected. Single infections were detected in 380 (80.2%) samples and mixed infections were detected in 94 (19.8%). Respiratory syncytial virus (138/583, 23.7%) and rhinovirus (130/583, 22.3%) were the most commonly identified viruses, followed by SARS-CoV-2 (82/583, 14.1%). Respiratory syncytial virus predominated until February, with 129 detections; it then decreased drastically in March to only nine detections. SARS-CoV-2 was absent in the study area until February 26, 2020 and then reached 82 detections in just over a month. SARS-CoV-2 was found in mixed infections in only three cases, all observed in children younger than 1 year old. Conclusions: This study showed a completely different trend between SARS-CoV-2 and the ‘common’ respiratory viruses: the common viruses mostly affected children, without any distinction according to sex, while SARS-CoV-2 mostly affected adult males.

Human respiratory viruses, including SARS-CoV-2, circulating in the winter season 2019–2020 in Parma, Northern Italy / Calderaro, A.; De Conto, F.; Buttrini, M.; Piccolo, G.; Montecchini, S.; Maccari, C.; Martinelli, M.; Di Maio, A.; Ferraglia, F.; Pinardi, F.; Montagna, P.; Arcangeletti, M. C.; Chezzi, C.. - In: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. - ISSN 1201-9712. - 102(2021), pp. 79-84. [10.1016/j.ijid.2020.09.1473]

Human respiratory viruses, including SARS-CoV-2, circulating in the winter season 2019–2020 in Parma, Northern Italy

Calderaro A.;De Conto F.;Buttrini M.;Piccolo G.;Montecchini S.;Maccari C.;Martinelli M.;Ferraglia F.;Pinardi F.;Arcangeletti M. C.;Chezzi C.
2021

Abstract

Objectives: The aim of this study was to determine the prevalence of respiratory virus infections, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the winter period December 2019 to March 2020, via a tertiary care hospital-based survey in Parma, Northern Italy. Methods: A total of 906 biological samples from the respiratory tract were analysed by both conventional assays (including culture) and molecular assays targeting nucleic acids of SARS-CoV-2 and other respiratory viruses. Results: Overall, 474 samples (52.3%) were positive for at least one virus, with a total of 583 viruses detected. Single infections were detected in 380 (80.2%) samples and mixed infections were detected in 94 (19.8%). Respiratory syncytial virus (138/583, 23.7%) and rhinovirus (130/583, 22.3%) were the most commonly identified viruses, followed by SARS-CoV-2 (82/583, 14.1%). Respiratory syncytial virus predominated until February, with 129 detections; it then decreased drastically in March to only nine detections. SARS-CoV-2 was absent in the study area until February 26, 2020 and then reached 82 detections in just over a month. SARS-CoV-2 was found in mixed infections in only three cases, all observed in children younger than 1 year old. Conclusions: This study showed a completely different trend between SARS-CoV-2 and the ‘common’ respiratory viruses: the common viruses mostly affected children, without any distinction according to sex, while SARS-CoV-2 mostly affected adult males.
Human respiratory viruses, including SARS-CoV-2, circulating in the winter season 2019–2020 in Parma, Northern Italy / Calderaro, A.; De Conto, F.; Buttrini, M.; Piccolo, G.; Montecchini, S.; Maccari, C.; Martinelli, M.; Di Maio, A.; Ferraglia, F.; Pinardi, F.; Montagna, P.; Arcangeletti, M. C.; Chezzi, C.. - In: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. - ISSN 1201-9712. - 102(2021), pp. 79-84. [10.1016/j.ijid.2020.09.1473]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2885874
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