The synthesis of a new fluorous protecting group, Froc, is described. This new fluorous tag has been used in peptide and carbohydrate synthesis by our group and readily allows us to fully characterize each product (NMR, MS) and monitor each synthetic step by TLC. Purification of the products is generally performed by standard fluorous solid-phase extraction techniques (e.g., F-SPE), but standard chromatographic purifications are also possible if required.

Froc: A new fluorous protective group for peptide and oligosaccharide synthesis / Manzoni, Leonardo; Castelli, Riccardo. - In: ORGANIC LETTERS. - ISSN 1523-7060. - 8:5(2006), pp. 955-957. [10.1021/ol060006e]

Froc: A new fluorous protective group for peptide and oligosaccharide synthesis

Riccardo Castelli
2006-01-01

Abstract

The synthesis of a new fluorous protecting group, Froc, is described. This new fluorous tag has been used in peptide and carbohydrate synthesis by our group and readily allows us to fully characterize each product (NMR, MS) and monitor each synthetic step by TLC. Purification of the products is generally performed by standard fluorous solid-phase extraction techniques (e.g., F-SPE), but standard chromatographic purifications are also possible if required.
2006
Froc: A new fluorous protective group for peptide and oligosaccharide synthesis / Manzoni, Leonardo; Castelli, Riccardo. - In: ORGANIC LETTERS. - ISSN 1523-7060. - 8:5(2006), pp. 955-957. [10.1021/ol060006e]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2874870
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