CASTELLI, Riccardo
CASTELLI, Riccardo
Dipartimento di Scienze degli Alimenti e del Farmaco
2,2-dimethyl-4-(4-methoxy-phenoxy) butanoate and 2,2-dimethyl-4-azido butanoate: Two new pivaloate-ester-like protecting groups
2013-01-01 Castelli, Riccardo; Overkleeft, Herman S.; Van Der Marel, Gijsbert A; Codée, Jeroen D. C.
2-Arylmelatonin analogues: Probing the 2-phenyl binding pocket of melatonin MT1 and MT2 receptors
2022-01-01 Mari, M.; Elisi, G. M.; Bedini, A.; Lucarini, S.; Retini, M.; Lucini, V.; Scaglione, F.; Vincenzi, F.; Varani, K.; Castelli, R.; Mor, M.; Rivara, S.; Spadoni, G.
A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [18F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging
2015-01-01 Matusiak, Nathalie; Castelli, Riccardo; Tuin, Adriaan W.; Overkleeft, Herman S.; Wisastra, Rosalina; Dekker, Frank J.; Prély, Laurette M.; Bischoff, Rainer P. M.; Van Waarde, Aren; Dierckx, Rudi A. J. O.; Elsinga, Philip H.
A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence
2023-01-01 Festuccia, Claudio; Corrado, Miriam; Rossetti, Alessandra; Castelli, Riccardo; Lodola, Alessio; Gravina, Giovanni Luca; Tognolini, Massimiliano; Giorgio, Carmine
A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine
2021-01-01 Ferlenghi, F; Scalvini, L; Vacondio, F; Castelli, R; Bozza, N; Marseglia, G; Rivara, S; Lodola, A; La Monica, S; Minari, R; Petronini, Pg; Alfieri, R; Tiseo, M; Mor, M.
Activation of glycosyl halides by halogen bonding
2014-01-01 Castelli, Riccardo; Schindler, Severin; Walter, Sebastian M.; Kniep, Florian; Overkleeft, Herman S.; Van Der Marel, Gijsbert A.; Huber, Stefan M.; Codée, Jeroen D. C.
Adlayers of dimannoside thiols on gold: Surface chemical analysis
2011-01-01 Dietrich, Paul M.; Horlacher, Tim; Girard-Lauriault, Pierre-Luc; Gross, Thomas; Lippitz, Andreas; Min, Hyegeun; Wirth, Thomas; Castelli, Riccardo; Seeberger, Peter H.; Unger, Wolfgang E. S.
Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats
2015-01-01 Vacondio, Federica; Bassi, Michele; Silva, Claudia; Castelli, Riccardo; Carmi, Caterina; Scalvini, Laura; Lodola, Alessio; Vivo, Valentina; Flammini, Lisa; Barocelli, Elisabetta; Mor, Marco; Rivara, Silvia
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR
2019-01-01 Castelli, R; Bozza, N; Cavazzoni, A; Bonelli, M; Vacondio, F; Ferlenghi, F; Callegari, D; Silva, C; Rivara, S; Lodola, A; Digiacomo, G; Fumarola, C; Alfieri, R; Petronini, Pg; Mor, M.
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines
2020-01-01 Castelli, Riccardo; Scalvini, Laura; Vacondio, Federica; Lodola, Alessio; Anselmi, Mattia; Vezzosi, Stefano; Carmi, Caterina; Bassi, Michele; Ferlenghi, Francesca; Rivara, Silvia; Moller Ingvar, R.; Rand Kasper, D.; Daglian, Jennifer; Wei, Don; Dotsey Emmanuel, Y.; Ahmed, Faizy; Jung, Kwang-Mook; Stella, Nephi; Singh, Simar; Mor, Marco; Piomelli, Daniele.
Cantilever array sensors detect specific carbohydrate-protein interactions with picomolar sensitivity
2011-01-01 Gruber, Kathrin; Horlacher, Tim; Castelli, Riccardo; Seeberger, Peter H.; Hermann, Bianca A.
Chemical modification of NSC12 leads to a specific FGF-trap with antitumor activity in multiple myeloma
2021-01-01 Castelli, R.; Taranto, S.; Furiassi, L.; Bozza, N.; Marseglia, G.; Ferlenghi, F.; Rivara, S.; Retini, M.; Bedini, A.; Spadoni, G.; Matarazzo, S.; Ronca, R.; Presta, M.; Mor, M.; Giacomini, A.
Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrin
2021-01-01 Rusnati, M.; Paiardi, G.; Tobia, C.; Urbinati, C.; Lodola, A.; D'Ursi, P.; Corrado, M.; Castelli, R.; Wade, R. C.; Tognolini, M.; Chiodelli, P.
Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction
2014-01-01 Pala, Daniele; Castelli, Riccardo; Incerti, Matteo; Russo, Simonetta; Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Zanotti, Ilaria; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio
Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction.
2014-01-01 Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Castelli, Riccardo; Pala, Daniele; Mor, Marco; Barocelli, Elisabetta; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio
Critical role of amino acid position 343 of surfactant protein-D in the selective binding of glycolipids from Mycobacterium tuberculosis
2009-01-01 Carlson Tracey, K.; Torrelles Jordi, B.; Smith, Kelly.; Horlacher, Tim.; Castelli, Riccardo; Seeberger Peter, H.; Crouch Erika, C.; Schlesinger Larry, S.
Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis
2014-01-01 HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta; Mor, Marco; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Tognolini, Massimiliano
Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity.
2015-01-01 Tognolini, Massimiliano; Giorgio, Carmine; Festuccia, C; Rusnati, M; Chiodelli, P; Incerti, Matteo; Pala, Daniele; Callegari, Donatella; Bertoni, Simona; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta
Discovery and development of small molecules targeting Eph-ephrin system in glioblastoma: an academic history
2017-01-01 Tognolini, Massimiliano; Claudio, Festuccia; Gianluca, Gravina; Castelli, Riccardo; Incerti, Matteo; Vacondio, Federica; Callegari, Donatella; Simonetta, Russo; Barocelli, Elisabetta; Marco, Rusnati; Paola, Chiodelli; Lodola, Alessio; Giorgio, Carmine
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line
2024-01-01 Guidetti, Lorenzo; Castelli, Riccardo; Zappia, Alfonso; Ferrari, Francesca Romana; Giorgio, Carmine; Barocelli, Elisabetta; Pagliaro, Luca; Vento, Federica; Roti, Giovanni; Scalvini, Laura; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2,2-dimethyl-4-(4-methoxy-phenoxy) butanoate and 2,2-dimethyl-4-azido butanoate: Two new pivaloate-ester-like protecting groups | 1-gen-2013 | Castelli, Riccardo; Overkleeft, Herman S.; Van Der Marel, Gijsbert A; Codée, Jeroen D. C. | |
| 2-Arylmelatonin analogues: Probing the 2-phenyl binding pocket of melatonin MT1 and MT2 receptors | 1-gen-2022 | Mari, M.; Elisi, G. M.; Bedini, A.; Lucarini, S.; Retini, M.; Lucini, V.; Scaglione, F.; Vincenzi, F.; Varani, K.; Castelli, R.; Mor, M.; Rivara, S.; Spadoni, G. | |
| A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [18F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging | 1-gen-2015 | Matusiak, Nathalie; Castelli, Riccardo; Tuin, Adriaan W.; Overkleeft, Herman S.; Wisastra, Rosalina; Dekker, Frank J.; Prély, Laurette M.; Bischoff, Rainer P. M.; Van Waarde, Aren; Dierckx, Rudi A. J. O.; Elsinga, Philip H. | |
| A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence | 1-gen-2023 | Festuccia, Claudio; Corrado, Miriam; Rossetti, Alessandra; Castelli, Riccardo; Lodola, Alessio; Gravina, Giovanni Luca; Tognolini, Massimiliano; Giorgio, Carmine | |
| A sulfonyl fluoride derivative inhibits EGFR L858R/T790M/C797S by covalent modification of the catalytic lysine | 1-gen-2021 | Ferlenghi, F; Scalvini, L; Vacondio, F; Castelli, R; Bozza, N; Marseglia, G; Rivara, S; Lodola, A; La Monica, S; Minari, R; Petronini, Pg; Alfieri, R; Tiseo, M; Mor, M. | |
| Activation of glycosyl halides by halogen bonding | 1-gen-2014 | Castelli, Riccardo; Schindler, Severin; Walter, Sebastian M.; Kniep, Florian; Overkleeft, Herman S.; Van Der Marel, Gijsbert A.; Huber, Stefan M.; Codée, Jeroen D. C. | |
| Adlayers of dimannoside thiols on gold: Surface chemical analysis | 1-gen-2011 | Dietrich, Paul M.; Horlacher, Tim; Girard-Lauriault, Pierre-Luc; Gross, Thomas; Lippitz, Andreas; Min, Hyegeun; Wirth, Thomas; Castelli, Riccardo; Seeberger, Peter H.; Unger, Wolfgang E. S. | |
| Amino acid derivatives as palmitoylethanolamide prodrugs: Synthesis, in vitro metabolism and in vivo plasma profile in rats | 1-gen-2015 | Vacondio, Federica; Bassi, Michele; Silva, Claudia; Castelli, Riccardo; Carmi, Caterina; Scalvini, Laura; Lodola, Alessio; Vivo, Valentina; Flammini, Lisa; Barocelli, Elisabetta; Mor, Marco; Rivara, Silvia | |
| Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR | 1-gen-2019 | Castelli, R; Bozza, N; Cavazzoni, A; Bonelli, M; Vacondio, F; Ferlenghi, F; Callegari, D; Silva, C; Rivara, S; Lodola, A; Digiacomo, G; Fumarola, C; Alfieri, R; Petronini, Pg; Mor, M. | |
| Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines | 1-gen-2020 | Castelli, Riccardo; Scalvini, Laura; Vacondio, Federica; Lodola, Alessio; Anselmi, Mattia; Vezzosi, Stefano; Carmi, Caterina; Bassi, Michele; Ferlenghi, Francesca; Rivara, Silvia; Moller Ingvar, R.; Rand Kasper, D.; Daglian, Jennifer; Wei, Don; Dotsey Emmanuel, Y.; Ahmed, Faizy; Jung, Kwang-Mook; Stella, Nephi; Singh, Simar; Mor, Marco; Piomelli, Daniele. | |
| Cantilever array sensors detect specific carbohydrate-protein interactions with picomolar sensitivity | 1-gen-2011 | Gruber, Kathrin; Horlacher, Tim; Castelli, Riccardo; Seeberger, Peter H.; Hermann, Bianca A. | |
| Chemical modification of NSC12 leads to a specific FGF-trap with antitumor activity in multiple myeloma | 1-gen-2021 | Castelli, R.; Taranto, S.; Furiassi, L.; Bozza, N.; Marseglia, G.; Ferlenghi, F.; Rivara, S.; Retini, M.; Bedini, A.; Spadoni, G.; Matarazzo, S.; Ronca, R.; Presta, M.; Mor, M.; Giacomini, A. | |
| Cholenic acid derivative UniPR1331 impairs tumor angiogenesis via blockade of VEGF/VEGFR2 in addition to Eph/ephrin | 1-gen-2021 | Rusnati, M.; Paiardi, G.; Tobia, C.; Urbinati, C.; Lodola, A.; D'Ursi, P.; Corrado, M.; Castelli, R.; Wade, R. C.; Tognolini, M.; Chiodelli, P. | |
| Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction | 1-gen-2014 | Pala, Daniele; Castelli, Riccardo; Incerti, Matteo; Russo, Simonetta; Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Zanotti, Ilaria; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio | |
| Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction. | 1-gen-2014 | Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Castelli, Riccardo; Pala, Daniele; Mor, Marco; Barocelli, Elisabetta; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio | |
| Critical role of amino acid position 343 of surfactant protein-D in the selective binding of glycolipids from Mycobacterium tuberculosis | 1-gen-2009 | Carlson Tracey, K.; Torrelles Jordi, B.; Smith, Kelly.; Horlacher, Tim.; Castelli, Riccardo; Seeberger Peter, H.; Crouch Erika, C.; Schlesinger Larry, S. | |
| Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis | 1-gen-2014 | HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta; Mor, Marco; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Tognolini, Massimiliano | |
| Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity. | 1-gen-2015 | Tognolini, Massimiliano; Giorgio, Carmine; Festuccia, C; Rusnati, M; Chiodelli, P; Incerti, Matteo; Pala, Daniele; Callegari, Donatella; Bertoni, Simona; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta | |
| Discovery and development of small molecules targeting Eph-ephrin system in glioblastoma: an academic history | 1-gen-2017 | Tognolini, Massimiliano; Claudio, Festuccia; Gianluca, Gravina; Castelli, Riccardo; Incerti, Matteo; Vacondio, Federica; Callegari, Donatella; Simonetta, Russo; Barocelli, Elisabetta; Marco, Rusnati; Paola, Chiodelli; Lodola, Alessio; Giorgio, Carmine | |
| Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line | 1-gen-2024 | Guidetti, Lorenzo; Castelli, Riccardo; Zappia, Alfonso; Ferrari, Francesca Romana; Giorgio, Carmine; Barocelli, Elisabetta; Pagliaro, Luca; Vento, Federica; Roti, Giovanni; Scalvini, Laura; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano |