Seizures are a frequent acute neurological event in the neonatal period. Up to 12 to 18% of all seizures in newborns are due to perinatal stroke and up to 39% of affected children can then develop epilepsy in childhood. We report the case of a young patient who presented stroke-related seizures in the neonatal period and then developed focal symptomatic epilepsy at 15 years of age, and in whom the epileptic focus was found to co-localize with the site of his ischemic brain lesion. Such a prolonged silent period before onset of remote symptomatic epilepsy has not previously been reported. This case suggests that newborns with seizures due to a neonatal stroke are at higher risk of epilepsy and that the epileptogenic process in these subjects can last longer than a decade.

A 15-year epileptogenic period after perinatal brain injury / Pisani, Francesco; Pavlidis, Elena; Facini, Carlotta; La Morgia, Chiara; Fusco, Carlo; Cantalupo, Gaetano. - In: FUNCTIONAL NEUROLOGY. - ISSN 0393-5264. - 32:1(2017), pp. 49-53. [10.11138/FNeur/2017.32.1.049]

A 15-year epileptogenic period after perinatal brain injury

PISANI, Francesco;PAVLIDIS, Elena;FACINI, Carlotta;FUSCO, Carlo;CANTALUPO, Gaetano
2017

Abstract

Seizures are a frequent acute neurological event in the neonatal period. Up to 12 to 18% of all seizures in newborns are due to perinatal stroke and up to 39% of affected children can then develop epilepsy in childhood. We report the case of a young patient who presented stroke-related seizures in the neonatal period and then developed focal symptomatic epilepsy at 15 years of age, and in whom the epileptic focus was found to co-localize with the site of his ischemic brain lesion. Such a prolonged silent period before onset of remote symptomatic epilepsy has not previously been reported. This case suggests that newborns with seizures due to a neonatal stroke are at higher risk of epilepsy and that the epileptogenic process in these subjects can last longer than a decade.
A 15-year epileptogenic period after perinatal brain injury / Pisani, Francesco; Pavlidis, Elena; Facini, Carlotta; La Morgia, Chiara; Fusco, Carlo; Cantalupo, Gaetano. - In: FUNCTIONAL NEUROLOGY. - ISSN 0393-5264. - 32:1(2017), pp. 49-53. [10.11138/FNeur/2017.32.1.049]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2824289
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