Cytotoxic T cells have been suggested to be responsible for lysis of hepatitis B virus (HBV)-infected hepatocytes and control of virus infection. The frequency, kinetics, phenotype, and capacity for clonal expansion of circulating HBV-specific CD8 cells were analyzed directly in patients with acute HBV infection to clarify their pathogenetic role.

Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection / Maini, M. K; Boni, C; Ogg, G. S; King, A. S; Reignat, S; Lee, C. K; Larrubia, J. R; Webster, G. J; Mcmichael, A. J; Ferrari, Carlo; Williams, R; Vergani, D; Bertoletti, A.. - In: GASTROENTEROLOGY. - ISSN 0016-5085. - 117:6(1999), p. 1386-96.

Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection

Boni, C;FERRARI, Carlo;
1999-01-01

Abstract

Cytotoxic T cells have been suggested to be responsible for lysis of hepatitis B virus (HBV)-infected hepatocytes and control of virus infection. The frequency, kinetics, phenotype, and capacity for clonal expansion of circulating HBV-specific CD8 cells were analyzed directly in patients with acute HBV infection to clarify their pathogenetic role.
1999
Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection / Maini, M. K; Boni, C; Ogg, G. S; King, A. S; Reignat, S; Lee, C. K; Larrubia, J. R; Webster, G. J; Mcmichael, A. J; Ferrari, Carlo; Williams, R; Vergani, D; Bertoletti, A.. - In: GASTROENTEROLOGY. - ISSN 0016-5085. - 117:6(1999), p. 1386-96.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2815122
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