Lamivudine therapy in patients with chronic hepatitis B can induce the recovery of antiviral T cell responses. It is unknown whether the recovery of T cell responsiveness is long-lasting and persists throughout the treatment and whether the elevation of viremia which follows therapy withdrawal can restore a condition of T cell unresponsiveness.

Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B / Boni, Carolina; Penna, Amalia; Bertoletti, Antonio; Lamonaca, Vincenzo; Rapti, Irene; Missale, Gabriele; Pilli, Massimo; Urbani, Simona; Cavalli, Albertina; Cerioni, Simona; Panebianco, Ruggero; Jenkins, Julian; Ferrari, Carlo. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - 39:4(2003), p. 595-605.

Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B

Boni, Carolina;Missale, Gabriele;FERRARI, Carlo
2003-01-01

Abstract

Lamivudine therapy in patients with chronic hepatitis B can induce the recovery of antiviral T cell responses. It is unknown whether the recovery of T cell responsiveness is long-lasting and persists throughout the treatment and whether the elevation of viremia which follows therapy withdrawal can restore a condition of T cell unresponsiveness.
2003
Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B / Boni, Carolina; Penna, Amalia; Bertoletti, Antonio; Lamonaca, Vincenzo; Rapti, Irene; Missale, Gabriele; Pilli, Massimo; Urbani, Simona; Cavalli, Albertina; Cerioni, Simona; Panebianco, Ruggero; Jenkins, Julian; Ferrari, Carlo. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - 39:4(2003), p. 595-605.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2815059
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 229
  • ???jsp.display-item.citation.isi??? 210
social impact