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A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from the Italian cohort replicated IL12A and IL12RB associations, and a combined meta-analysis using a Canadian dataset identified newly associated loci at SPIB (P = 7.9 × 10-11, odds ratio (OR) = 1.46), IRF5-TNPO3 (P = 2.8 × 10 -10, OR = 1.63) and 17q12-21 (P = 1.7 × 10-10, OR = 1.38). © 2010 Nature America, Inc. All rights reserved.

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis / Liu, X., Invernizzi, P., Lu, Y., Kosoy, R., Lu, Y., Bianchi, I., Podda, M., Xu, C., Xie, G., Macciardi, F., Selmi, C., Lupoli, S., Shigeta, R., Ransom, M., Lleo, A., Lee, A.T., Mason, A.L., Myers, R.P., Peltekian, K.M., Ghent, C.N., et al.. - In: NATURE GENETICS. - ISSN 1061-4036. - 42:8(2010), pp. 658-660. [10.1038/ng.627]

Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis

FERRARI, Carlo;
2010-01-01

Abstract

A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort. The results from the Italian cohort replicated IL12A and IL12RB associations, and a combined meta-analysis using a Canadian dataset identified newly associated loci at SPIB (P = 7.9 × 10-11, odds ratio (OR) = 1.46), IRF5-TNPO3 (P = 2.8 × 10 -10, OR = 1.63) and 17q12-21 (P = 1.7 × 10-10, OR = 1.38). © 2010 Nature America, Inc. All rights reserved.
2010
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis / Liu, X., Invernizzi, P., Lu, Y., Kosoy, R., Lu, Y., Bianchi, I., Podda, M., Xu, C., Xie, G., Macciardi, F., Selmi, C., Lupoli, S., Shigeta, R., Ransom, M., Lleo, A., Lee, A.T., Mason, A.L., Myers, R.P., Peltekian, K.M., Ghent, C.N., et al.. - In: NATURE GENETICS. - ISSN 1061-4036. - 42:8(2010), pp. 658-660. [10.1038/ng.627]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2814745
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