In the matter of foodborne mycotoxins, beside a number of regulated compounds, regulations are totally missing for phase-II plant metabolites - the toxicological knowledge of which is still in its infancy. Currently, zearalenone-14-glucoside is in the pipeline and its toxicological role is under a glowing scientific debate. In our work it clearly showed high toxicological concerns as it is prone to conversion to well-known toxic compounds (i.e. zearalenone and both zearalenol isomers) when exposed to breast cancer cells culture. The need of future risk assessment studies has been pointed out accordingly.
On the masked mycotoxin zearalenone-14-glucoside. Does the mask truly hide? / Dellafiora, Luca; Perotti, Alessio; Galaverna, Gianni; Buschini, Annamaria; Dall'Asta, Chiara. - In: TOXICON. - ISSN 0041-0101. - 111:(2016), pp. 139-142. [10.1016/j.toxicon.2016.01.053]
On the masked mycotoxin zearalenone-14-glucoside. Does the mask truly hide?
DELLAFIORA, Luca;PEROTTI, Alessio;GALAVERNA, Gianni;BUSCHINI, Annamaria;DALL'ASTA, Chiara
2016-01-01
Abstract
In the matter of foodborne mycotoxins, beside a number of regulated compounds, regulations are totally missing for phase-II plant metabolites - the toxicological knowledge of which is still in its infancy. Currently, zearalenone-14-glucoside is in the pipeline and its toxicological role is under a glowing scientific debate. In our work it clearly showed high toxicological concerns as it is prone to conversion to well-known toxic compounds (i.e. zearalenone and both zearalenol isomers) when exposed to breast cancer cells culture. The need of future risk assessment studies has been pointed out accordingly.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
