A new approach to cancer treatment using low-energy gamma-rays is discussed. Cultures of bone marrow mononuclear cells collected from normal donors and patients with chronic myelogenous leukaemia have been studied after the addition of hematin, at different concentrations, and irradiation by a Mössbauer gamma-ray source. Growth stimulation has been observed when hematin is added to normal bone marrow cultures, while growth inhibition is observed when hematin is added to leukaemic cultures. The effect becomes then more pronounced when hematin is used in combination with Mössbauer gamma-rays. © 1992 Società Italiana di Fisica.
Gamma-rays from Mössbauer sources: a low-dose approach to cancer therapy / Ortalli, I; Pedrazzi, G.; Jiang, K.; Zhang, X.; Carlo-Stella, C.; Rizzoli, V.. - In: NUOVO CIMENTO DELLA SOCIETÀ ITALIANA DI FISICA. D CONDENSED MATTER, ATOMIC, MOLECULAR AND CHEMICAL PHYSICS, BIOPHYSICS. - ISSN 0392-6737. - 14:4(1992), pp. 351-358. [10.1007/BF02456770]
Gamma-rays from Mössbauer sources: a low-dose approach to cancer therapy
ORTALLI, Ida;PEDRAZZI, Giuseppe;RIZZOLI, Vittorio
1992
Abstract
A new approach to cancer treatment using low-energy gamma-rays is discussed. Cultures of bone marrow mononuclear cells collected from normal donors and patients with chronic myelogenous leukaemia have been studied after the addition of hematin, at different concentrations, and irradiation by a Mössbauer gamma-ray source. Growth stimulation has been observed when hematin is added to normal bone marrow cultures, while growth inhibition is observed when hematin is added to leukaemic cultures. The effect becomes then more pronounced when hematin is used in combination with Mössbauer gamma-rays. © 1992 Società Italiana di Fisica.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
