Laboratory hematology provides an essential contribution to diagnostics and therapeutic management of most – if not all – hematological disorders. The introduction of automated flow cytometry has represented a remarkable advancement for laboratory workout, enabling several drawbacks of manual microscopy for enumeration and classification of blood cells to be overcome, which is typically plagued by a low throughput, high inter-observer variability and unsuitability for statistical testing [ 1 ], along with the possibility to gene rate post-analytical errors for manual transcription of results [ 2 ]. Nevertheless, due to the rather different technological approaches, an accurate evaluation of analytical performance and diagnostic accuracy of the single hemocytometers is necessary before they can be broadly introduced for routine testing. The aim of this study was a preliminary evaluation of complete blood cell (CBC) count on Mindray BC-6800, including white blood cell (WBC), red blood cell (RBC) and platelet (PLT) counts, hemoglobin (Hb), hematocrit (Ht), mean corpuscular volume (MCV), mean platelet volume (MPV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and RBC distribution width (RDW).
Preliminary evaluation of complete blood cell count on Mindray BC-6800 / Lippi, G; Cattabiani, C; Bonomini, S; Bardi, M; Pipitone, S; Aversa, Franco. - In: CLINICAL CHEMISTRY AND LABORATORY MEDICINE. - ISSN 1434-6621. - 51:4(2013), pp. 65-67. [10.1515/cclm-2012-0620]
Preliminary evaluation of complete blood cell count on Mindray BC-6800
AVERSA, Franco
2013-01-01
Abstract
Laboratory hematology provides an essential contribution to diagnostics and therapeutic management of most – if not all – hematological disorders. The introduction of automated flow cytometry has represented a remarkable advancement for laboratory workout, enabling several drawbacks of manual microscopy for enumeration and classification of blood cells to be overcome, which is typically plagued by a low throughput, high inter-observer variability and unsuitability for statistical testing [ 1 ], along with the possibility to gene rate post-analytical errors for manual transcription of results [ 2 ]. Nevertheless, due to the rather different technological approaches, an accurate evaluation of analytical performance and diagnostic accuracy of the single hemocytometers is necessary before they can be broadly introduced for routine testing. The aim of this study was a preliminary evaluation of complete blood cell (CBC) count on Mindray BC-6800, including white blood cell (WBC), red blood cell (RBC) and platelet (PLT) counts, hemoglobin (Hb), hematocrit (Ht), mean corpuscular volume (MCV), mean platelet volume (MPV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and RBC distribution width (RDW).File | Dimensione | Formato | |
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