Ultrastructural characterization and localization of intracellular immunoglobulin in peripheral blood mononuclear cells from a patient with hairy cell leukemia were studied by the direct immunoperoxidase technique. Approximately 20--30% of hairy cells stained positive for gamma-heavy and K-light chains, and this staining was limited to certain rough endoplasmic reticulum profiles. These ultrastructural findings can be considered an additional argument for the B cell origin of hairy cells.
Topographical localization of intracellular immunoglobulins in hairy cells by immunoelectron microscopy / MF. Martelli ; B. Falini; A. Tabilio; F. Aversa. - In: ACTA HAEMATOLOGICA. - ISSN 0001-5792. - 64(1980), pp. 251-255.
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