An original and highly efficient Oxone® cleavage methodology for the solid-phase synthesis of substituted uracils has been developed. An example of application of this methodology to the solid-phase synthesis of uridine derivatives is also reported.
Solid-phase synthesis (SPS) of substituted uracils via Oxone® cleavage methodology / Elena Petricci;Michela Renzulli;Marco Radi;Federico Corelli;Maurizio Botta. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 43(2002), pp. 9667-9670. [10.1016/S0040-4039(02)02380-8]