The pyrimidine scaffold represents an important pharmacophore endowed with a wide range of pharmacological activities according to the specific decoration of the heterocycle. This perspective article will briefly outline the most interesting approaches recently reported for the synthesis of highly functionalized pyrimidine derivatives.
Recent highlights in the synthesis of highly functionalized pyrimidines / Marco Radi;Silvia Schenone;Maurizio Botta. - In: ORGANIC & BIOMOLECULAR CHEMISTRY. - ISSN 1477-0520. - 7(2009), pp. 2841-2847. [10.1039/b906445a]