A rapid protocol for the multicomponent microwave-assisted organocatalytic domino Knoevenagel/hetero Diels-Alder reaction (DKHDA) has been developed for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. The reported procedure could be used for the fast generation of novel substituted 2,3-dihydropyran[2,3-c] pyrazoles with potential anti-tuberculosis activity.
Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels–Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles / Radi, Marco; Vincenzo, Bernardo; Beatrice, Bechi; Daniele, Castagnolo; Mafalda, Pagano; Maurizio, Botta. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 50:(2009), pp. 6572-6575. [10.1016/j.tetlet.2009.09.047]
Microwave-assisted organocatalytic multicomponent Knoevenagel/hetero Diels–Alder reaction for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles
RADI, Marco;
2009-01-01
Abstract
A rapid protocol for the multicomponent microwave-assisted organocatalytic domino Knoevenagel/hetero Diels-Alder reaction (DKHDA) has been developed for the synthesis of 2,3-dihydropyran[2,3-c]pyrazoles. The reported procedure could be used for the fast generation of novel substituted 2,3-dihydropyran[2,3-c] pyrazoles with potential anti-tuberculosis activity.| File | Dimensione | Formato | |
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