Dioxin as referred to this abstract cover a group of 75 polychlorinated dibenzo- p-dioxin (PCDD) congeners and 135 polychlorinated dibenzofuran (PCDF) congeners, 17 of which are toxicological concern Polyclorinated biphenyls (PCBs) are a group of 209 different congeners which can be divided into two groups according to their toxicological properities: a small number exibits toxicological properties similar to dioxins and are therefore often named “dioxin-like PCBs’. The majority do not exhibit dioxin-like toxicity but has a different toxicological profile. In human tissue were found the following substances: 2,3,7,8- TCDD,1,2,3,7,8 PCDD,1,2,3,6,7,8-Hx CDD,2,3,4,7,8-PCDF, PCB 126 which represent 80% of total TEQ. The SCF fixed a tolerable weekly intake (TWI) of 14 pg WHO-TEQ/kg body weitgh for dioxin and dioxin-like PCBs. Exposure estimate indicate that a considerable proportion of the Community population have a dietary intake in excess of TWI (8-21 pgTEQ/g fat). The reduction of human exposure to dioxins and dioxin-like PCBs through food consumption is important and necessary to ensure consumer protection. Therefore all food chain operators must continue to make all possible effort and to do all is necessary to limit the dioxins and PCBs present in food, according to maximum leveles fixed in the Rgulations (EC) n. 466/2001 and 199/2006.In this Regulation it is proposed to set maximum levels for the total amount of dioxins and dioxin-like PCBs expressed in World Health Organisation (WHO) toxic equivalents, using the WHO-TEFs. The hightest concentration have been observed in: dairy, milk, beef, pork, poultry, other meats, freshwater fish and shellfish, marine fish and shellfish
DIOSSINE, FURANI PCB E ALIMENTI DI ORIGINE ANIMALESTATO DELL’ARTE / Pizzin Gisella; Stefano Bentley. - In: ANNALI DELLA FACOLTÀ DI MEDICINA VETERINARIA. UNIVERSITÀ DI PARMA. - ISSN 0393-4802. - 26(2006), pp. 247-264.