The chloromethylation of calix[4]arene 1a and of the methyl ethers of calix[6]arene 1b and calix[8]arene 1c, using chloromethyl n-octyl ether and SnCl4 in chloroform at room temperature has been performed in good yield for the first time. The chloromethylated products 2a-c have been used as intermediates to introduce on calixarenes phosphonic acid groups which render these macrocycles water soluble and potentially useful in Host Guest Chemistry.

Chloromethylation of Calix[4]arenes and Synthesis of New Water Soluble Macrocyclic Hosts / M. ALMI; A. ARDUINI; A. CASNATI; A. POCHINI; R. UNGARO. - In: TETRAHEDRON. - ISSN 0040-4020. - 45(1989), pp. 2177-2182. [10.1016/S0040-4020(01)80077-6]

Chloromethylation of Calix[4]arenes and Synthesis of New Water Soluble Macrocyclic Hosts

ARDUINI, Arturo;CASNATI, Alessandro;POCHINI, Andrea;UNGARO, Rocco
1989

Abstract

The chloromethylation of calix[4]arene 1a and of the methyl ethers of calix[6]arene 1b and calix[8]arene 1c, using chloromethyl n-octyl ether and SnCl4 in chloroform at room temperature has been performed in good yield for the first time. The chloromethylated products 2a-c have been used as intermediates to introduce on calixarenes phosphonic acid groups which render these macrocycles water soluble and potentially useful in Host Guest Chemistry.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2313222
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