Beyond Lindlar and without hydrogen: Transfer hydrogenation of internal alkynes catalyzed by a palladium(0) catalyst containing an N-heterocyclic carbene ligand gives Z alkenes without overreduction to alkanes (see scheme). Contrary to most transfer hydrogenations, ketones are not reduced. As such, this is the first catalyst that shows excellent stereo- and chemoselectivity for the semihydrogenation of alkynes without the need for hydrogen gas.

Transfer semihydrogenation of alkynes catalyzed by a zero-valent palladium N-heterocyclic carbene complex / Hauwert, P.; Maestri, Giovanni; Sprengers, J. W.; Catellani, Marta; Elsevier, C. J.. - In: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION. - ISSN 1433-7851. - 47:(2008), pp. 3223-3226. [10.1002/anie.200705638]

Transfer semihydrogenation of alkynes catalyzed by a zero-valent palladium N-heterocyclic carbene complex

MAESTRI, Giovanni;CATELLANI, Marta;
2008-01-01

Abstract

Beyond Lindlar and without hydrogen: Transfer hydrogenation of internal alkynes catalyzed by a palladium(0) catalyst containing an N-heterocyclic carbene ligand gives Z alkenes without overreduction to alkanes (see scheme). Contrary to most transfer hydrogenations, ketones are not reduced. As such, this is the first catalyst that shows excellent stereo- and chemoselectivity for the semihydrogenation of alkynes without the need for hydrogen gas.
2008
Transfer semihydrogenation of alkynes catalyzed by a zero-valent palladium N-heterocyclic carbene complex / Hauwert, P.; Maestri, Giovanni; Sprengers, J. W.; Catellani, Marta; Elsevier, C. J.. - In: ANGEWANDTE CHEMIE. INTERNATIONAL EDITION. - ISSN 1433-7851. - 47:(2008), pp. 3223-3226. [10.1002/anie.200705638]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/1768137
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