FERLENGHI, FRANCESCA

FERLENGHI, FRANCESCA  

Dipartimento di Scienze degli Alimenti e del Farmaco  

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Risultati 1 - 20 di 22 (tempo di esecuzione: 0.028 secondi).
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(2S,4R)-4-fluoroglutamine is converted into (2S,4R)-4-fluoroglutamate by glutaminase activity and may be exploited as a PET tracer in glutamine-addicted cancers 1-gen-2021 Chiu, Martina; Toscani, Denise; Ferlenghi, Francesca; Taurino, Giuseppe; Sartori, Andrea; Vacondio, Federica; Zanardi, Franca; Giuliani, Nicola; Bussolati, Ovidio
Antidepressant-like effects of pharmacological inhibition of FAAH activity in socially isolated female rats 1-gen-2020 Carnevali, L.; Statello, R.; Vacondio, F.; Ferlenghi, F.; Spadoni, G.; Rivara, S.; Mor, M.; Sgoifo, A.
Antidepressant-like effects of pharmacological inhibition of FAAH activity in socially isolated female rats 1-gen-2020 Carnevali, L.; Statello, R.; Vacondio, F.; Ferlenghi, F.; Spadoni, G.; Rivara, S.; Mor, M.; Sgoifo, A.
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 1-gen-2019 Castelli, R; Bozza, N; Cavazzoni, A; Bonelli, M; Vacondio, F; Ferlenghi, F; Callegari, D; Silva, C; Rivara, S; Lodola, A; Digiacomo, G; Fumarola, C; Alfieri, R; Petronini, Pg; Mor, M.
Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines 1-gen-2020 Castelli, Riccardo; Scalvini, Laura; Vacondio, Federica; Lodola, Alessio; Anselmi, Mattia; Vezzosi, Stefano; Carmi, Caterina; Bassi, Michele; Ferlenghi, Francesca; Rivara, Silvia; Moller Ingvar, R.; Rand Kasper, D.; Daglian, Jennifer; Wei, Don; Dotsey Emmanuel, Y.; Ahmed, Faizy; Jung, Kwang-Mook; Stella, Nephi; Singh, Simar; Mor, Marco; Piomelli, Daniele.
Cell-targeted c(AmpRGD)-sunitinib molecular conjugates impair tumor growth of melanoma 1-gen-2019 Bianchini, Francesca; Portioli, Elisabetta; Ferlenghi, Francesca; Vacondio, Federica; Andreucci, Elena; Biagioni, Alessio; Ruzzolini, Jessica; Peppicelli, Silvia; Lulli, Matteo; Calorini, Lido; Battistini, Lucia; Zanardi, Franca; Sartori, Andrea
Chemical modification of NSC12 leads to a specific FGF-trap with antitumor activity in multiple myeloma 1-gen-2021 Castelli, R.; Taranto, S.; Furiassi, L.; Bozza, N.; Marseglia, G.; Ferlenghi, F.; Rivara, S.; Retini, M.; Bedini, A.; Spadoni, G.; Matarazzo, S.; Ronca, R.; Presta, M.; Mor, M.; Giacomini, A.
Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity in Vivo 1-gen-2020 Mugnaini, C.; Kostrzewa, M.; Bryk, M.; Mahmoud, A. M.; Brizzi, A.; Lamponi, S.; Giorgi, G.; Ferlenghi, F.; Vacondio, F.; Maccioni, P.; Colombo, G.; Mor, M.; Starowicz, K.; Di Marzo, V.; Ligresti, A.; Corelli, F.
Drug-gut microbiota metabolic interactions: the case of UniPR1331, selective antagonist of the Eph-ephrin system, in mice 1-gen-2020 Ferlenghi, F.; Castelli, R.; Scalvini, L.; Giorgio, C.; Corrado, M.; Tognolini, M.; Mor, M.; Lodola, A.; Vacondio, F.
Eph/ephrin targeting with a small molecule improves glucose tolerance in healthy and insulin-resistant mice 1-gen-2018 Tognolini, M.; Giorgio, C.; Incerti, M.; Ferlenghi, F.; Chiodelli, P.; Rusnati, M.; Cantoni, A.; Di Lecce, R.; Bertoni, S.; Manenti, F.; Piemonti, L.; Lodola, A.; Barocelli, E.
Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell Lines. 1-gen-2019 Fumarola, C; Bozza, N; Castelli, R; Ferlenghi, F; Marseglia, Giuseppe; Lodola, A; Bonelli, M; La Monica, S; Cretella, D; Alfieri, R; Minari, R; Galetti, M; Tiseo, M; Ardizzoni, A; Mor, M; Petronini, Pg.
The GABAB receptor positive allosteric modulator COR659: In vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives 1-gen-2020 Ferlenghi, F.; Maccioni, P.; Mugnaini, C.; Brizzi, A.; Fara, F.; Mostallino, R.; Paola, C. M.; Colombo, G.; Mor, M.; Vacondio, F.; Corelli, F.
Identification of Human Alanine-Glyoxylate Aminotransferase Ligands as Pharmacological Chaperones for Variants Associated with Primary Hyperoxaluria Type 1 1-gen-2022 Grottelli, Silvia; Annunziato, Giannamaria; Pampalone, Gioena; Pieroni, Marco; Dindo, Mirco; Ferlenghi, Francesca; Costantino, Gabriele; Cellini, Barbara
Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice 1-gen-2019 Giorgio, C; Incerti, M; Pala, D; Russo, S; Chiodelli, P; Rusnati, M; Cantoni, Am; Di Lecce, R; Barocelli, E; Bertoni, S; Ravassard, P; Manenti, F; Piemonti, L; Ferlenghi, F; Lodola, A; Tognolini, M.
Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph–Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavailability in Mice 1-gen-2022 Ferlenghi, F.; Giorgio, C.; Incerti, M.; Guidetti, L.; Chiodelli, P.; Rusnati, M.; Tognolini, M.; Vacondio, F.; Mor, M.; Lodola, A.
N-(Anilinoethyl)amide Melatonergic Ligands with Improved Water Solubility and Metabolic Stability 1-gen-2021 Ferlenghi, F.; Mari, M.; Gobbi, G.; Elisi, G. M.; Mor, M.; Rivara, S.; Vacondio, F.; Bartolucci, S.; Bedini, A.; Fanini, F.; Spadoni, G.
Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties 1-gen-2020 Incerti, M.; Russo, S.; Corrado, M.; Giorgio, C.; Ballabeni, V.; Chiodelli, P.; Rusnati, M.; Scalvini, L.; Callegari, D.; Castelli, R.; Vacondio, F.; Ferlenghi, F.; Tognolini, M.; Lodola, A.
Palladium Catalyst Recycling for Heck-Cassar-Sonogashira Cross-Coupling Reactions in Green Solvent/Base Blend 1-gen-2021 Fantoni, T.; Bernardoni, S.; Mattellone, A.; Martelli, G.; Ferrazzano, L.; Cantelmi, P.; Corbisiero, D.; Tolomelli, A.; Cabri, W.; Vacondio, F.; Ferlenghi, F.; Mor, M.; Ricci, A.
Pharmacological evaluation of new bioavailable small molecules targeting Eph/ephrin interaction 1-gen-2018 Giorgio, Carmine; Incerti, Matteo; Corrado, Miriam; Rusnati, Marco; Chiodelli, Paola; Russo, Simonetta; Callegari, Donatella; Ferlenghi, Francesca; Ballabeni, Vigilio; Barocelli, Elisabetta; Lodola, Alessio; Tognolini, Massimiliano
Protein-Protein Interaction Inhibitors Targeting the Eph-Ephrin System with a Focus on Amino Acid Conjugates of Bile Acids 1-gen-2022 Guidetti, L.; Castelli, R.; Scalvini, L.; Ferlenghi, F.; Corrado, M.; Giorgio, C.; Tognolini, M.; Lodola, A.