TOGNOLINI, Massimiliano
TOGNOLINI, Massimiliano
Dipartimento di Scienze degli Alimenti e del Farmaco
1,5-Benzodiazepines Part XIII. Substututed 4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-amines and 4H-imidazo-[1,2-a][ 1,5]benzodiazepin-5-amines as analgesic, anti-inflammatory and/or antipyretic agents with low acute toxicity
2002-01-01 G., Grossi; M., DI BRACCIO; G., Roma; Ballabeni, Vigilio; Tognolini, Massimiliano; F., Calcina; Barocelli, Elisabetta
1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5 amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6 carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10Hpyrimido[1,2-a [1,8]naphthyridine-6-carboxamide derivative
2014-01-01 M., Di Braccio; G., Grossi; S., Alfei; Ballabeni, Vigilio; Tognolini, Massimiliano; Flammini, Lisa; Giorgio, Carmine; Bertoni, Simona; Barocelli, Elisabetta
1,8-Naphthyridines V. Novel N-substituted 5-amino-N,N-diethyl-9-isopropyl [1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamides, as potent anti-inflammatory and/or analgesic agents completely devoid of acute gastrolesivity
2005-01-01 Grossi, G; DI BRACCIO, M; Roma, G; Ballabeni, Vigilio; Tognolini, Massimiliano; Barocelli, Elisabetta
1,8-Naphthyridines VII. New substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides and their isosteric analogues, exhibiting notable anti-inflammatory and/or analgesic activities, but no acute gastrolesivity.
2008-01-01 Roma, G; Grossi, G; DI BRACCIO, M; Piras, D; Ballabeni, Vigilio; Tognolini, Massimiliano; Bertoni, Simona; Barocelli, Elisabetta
1,8-Naphthyridines VIII. Novel 5-aminoimidazo[1,2-a] [1,8]naphthyridine-6-carboxamide and 5-amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamide derivatives showing potent analgesic or anti-inflammatory activity, respectively, and completely devoid of acute gastrolesivity.
2010-01-01 Roma, G.; DI BRACCIO, M.; Grossi, G.; Piras, D.; Ballabeni, Vigilio; Tognolini, Massimiliano; Bertoni, Simona; Barocelli, Elisabetta
1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors
2009-01-01 Bruno, O.; Brullo, C.; Bondavalli, F.; Schenone, S.; Spisani, S.; Falzarano, M. S.; Varani, K.; Barocelli, Elisabetta; Ballabeni, Vigilio; Giorgio, Carmine; Tognolini, Massimiliano
2,4-Substituted benzopyrano[4,3-d]pyrimidines and benzopyrano[4,3-d]pyrimidin-5-ones: synthesis and antiplatelet activity
2004-01-01 C., Brullo; O., Bruno; S., Schenone; A., Ranise; F., Bondavalli; Tognolini, Massimiliano; Ballabeni, Vigilio; Barocelli, Elisabetta
2-Amino-1,2-benzisothiazolin-3-one derivatives as powerful antiplatelet agents
1999-01-01 Vicini, Paola; M., Sospiri; Ballabeni, Vigilio; Tognolini, Massimiliano; Barocelli, Elisabetta
2-Amino-1,2-benzisothiazolin-3-one Derivatives: Synthesis and Assessment of their Antiplatelet/Spasmolytic Effects
2000-01-01 Vicini, Paola; Amoretti, L; Ballabeni, Vigilio; Tognolini, Massimiliano; Barocelli, Elisabetta
2-Amino/azido/hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological evaluation
2007-01-01 Bruno, O; Brullo, C; Bondavalli, F; Ranise, A; Schenone, S; Tognolini, Massimiliano; Ballabeni, Vigilio; Barocelli, Elisabetta
270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors
2014-01-01 Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio
5-Alkoxy-2-hydrazino and 5-methoxy-2-amino-5H[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological activity
2005-01-01 O., Bruno; C., Brullo; S., Schenone; F., Bondavalli; Tognolini, Massimiliano; Ballabeni, Vigilio; Barocelli, Elisabetta
5-substituted derivatives of 6-amino-1,3-diphenyl-2-thioxo-2.3-dihydropyrimidin-4(1H9-one as a new class of potent inhibitors of interleukin 8-induced chemotaxis
2008-01-01 Sara, Cesarini; Andrea, Spallarossa; Angelo, Ranise; Olga, Bruno; Nicoletta, Arduino; Franco, Dallegri; Tognolini, Massimiliano; Barocelli, Elisabetta
6-amino-4-oxo-1,3-diphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl derivatives as a new class of potent inhibitors of Interleukin-8-induced neutrophil chemotaxis.
2009-01-01 Cesarini, S; Spallarossa, A; Ranise, A; Bruno, O; Arduino, N; Bertolotto, M; Dallegri, F; Tognolini, Massimiliano; Gobbetti, Thomas; Barocelli, Elisabetta
A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence
2023-01-01 Festuccia, Claudio; Corrado, Miriam; Rossetti, Alessandra; Castelli, Riccardo; Lodola, Alessio; Gravina, Giovanni Luca; Tognolini, Massimiliano; Giorgio, Carmine
A photosensitizing fusion protein with targeting capabilities
2022-01-01 Bruno, S.; Margiotta, M.; Cozzolino, M.; Bianchini, P.; Diaspro, A.; Cavanna, L.; Tognolini, M.; Abbruzzetti, S.; Viappiani, C.
A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients
2013-01-01 Caligiani, Augusta; Giulia, Malavasi; Palla, Gerardo Giovanni; Marseglia, Angela; Tognolini, Massimiliano; Bruni, Renato
Accommodation and peristalsis are functional responses to chronic obstruction in rat hypertrophic ileum
2010-01-01 Bertoni, Simona; Flammini, Lisa; Saccani, Francesca; Ballabeni, Vigilio; G., Vegezzi; Tognolini, Massimiliano; Barocelli, Elisabetta
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.
2013-01-01 Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Noberini, R; Pasquale, Eb; Vicini, Paola; Piersanti, Silvia; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
Analgesic properties of benzisothiazole/ benzimidazole derivatives with acidic groups
2000-01-01 Vicini, Paola; L., Amoretti; Ballabeni, Vigilio; Tognolini, Massimiliano; Chiavarini, Milena; F., Calcina; Barocelli, Elisabetta
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,5-Benzodiazepines Part XIII. Substututed 4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-amines and 4H-imidazo-[1,2-a][ 1,5]benzodiazepin-5-amines as analgesic, anti-inflammatory and/or antipyretic agents with low acute toxicity | 1-gen-2002 | G., Grossi; M., DI BRACCIO; G., Roma; Ballabeni, Vigilio; Tognolini, Massimiliano; F., Calcina; Barocelli, Elisabetta | |
| 1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5 amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6 carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10Hpyrimido[1,2-a [1,8]naphthyridine-6-carboxamide derivative | 1-gen-2014 | M., Di Braccio; G., Grossi; S., Alfei; Ballabeni, Vigilio; Tognolini, Massimiliano; Flammini, Lisa; Giorgio, Carmine; Bertoni, Simona; Barocelli, Elisabetta | |
| 1,8-Naphthyridines V. Novel N-substituted 5-amino-N,N-diethyl-9-isopropyl [1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamides, as potent anti-inflammatory and/or analgesic agents completely devoid of acute gastrolesivity | 1-gen-2005 | Grossi, G; DI BRACCIO, M; Roma, G; Ballabeni, Vigilio; Tognolini, Massimiliano; Barocelli, Elisabetta | |
| 1,8-Naphthyridines VII. New substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides and their isosteric analogues, exhibiting notable anti-inflammatory and/or analgesic activities, but no acute gastrolesivity. | 1-gen-2008 | Roma, G; Grossi, G; DI BRACCIO, M; Piras, D; Ballabeni, Vigilio; Tognolini, Massimiliano; Bertoni, Simona; Barocelli, Elisabetta | |
| 1,8-Naphthyridines VIII. Novel 5-aminoimidazo[1,2-a] [1,8]naphthyridine-6-carboxamide and 5-amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamide derivatives showing potent analgesic or anti-inflammatory activity, respectively, and completely devoid of acute gastrolesivity. | 1-gen-2010 | Roma, G.; DI BRACCIO, M.; Grossi, G.; Piras, D.; Ballabeni, Vigilio; Tognolini, Massimiliano; Bertoni, Simona; Barocelli, Elisabetta | |
| 1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors | 1-gen-2009 | Bruno, O.; Brullo, C.; Bondavalli, F.; Schenone, S.; Spisani, S.; Falzarano, M. S.; Varani, K.; Barocelli, Elisabetta; Ballabeni, Vigilio; Giorgio, Carmine; Tognolini, Massimiliano | |
| 2,4-Substituted benzopyrano[4,3-d]pyrimidines and benzopyrano[4,3-d]pyrimidin-5-ones: synthesis and antiplatelet activity | 1-gen-2004 | C., Brullo; O., Bruno; S., Schenone; A., Ranise; F., Bondavalli; Tognolini, Massimiliano; Ballabeni, Vigilio; Barocelli, Elisabetta | |
| 2-Amino-1,2-benzisothiazolin-3-one derivatives as powerful antiplatelet agents | 1-gen-1999 | Vicini, Paola; M., Sospiri; Ballabeni, Vigilio; Tognolini, Massimiliano; Barocelli, Elisabetta | |
| 2-Amino-1,2-benzisothiazolin-3-one Derivatives: Synthesis and Assessment of their Antiplatelet/Spasmolytic Effects | 1-gen-2000 | Vicini, Paola; Amoretti, L; Ballabeni, Vigilio; Tognolini, Massimiliano; Barocelli, Elisabetta | |
| 2-Amino/azido/hydrazino-5-alkoxy-5H-[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological evaluation | 1-gen-2007 | Bruno, O; Brullo, C; Bondavalli, F; Ranise, A; Schenone, S; Tognolini, Massimiliano; Ballabeni, Vigilio; Barocelli, Elisabetta | |
| 270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors | 1-gen-2014 | Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio | |
| 5-Alkoxy-2-hydrazino and 5-methoxy-2-amino-5H[1]benzopyrano[4,3-d]pyrimidines: synthesis and pharmacological activity | 1-gen-2005 | O., Bruno; C., Brullo; S., Schenone; F., Bondavalli; Tognolini, Massimiliano; Ballabeni, Vigilio; Barocelli, Elisabetta | |
| 5-substituted derivatives of 6-amino-1,3-diphenyl-2-thioxo-2.3-dihydropyrimidin-4(1H9-one as a new class of potent inhibitors of interleukin 8-induced chemotaxis | 1-gen-2008 | Sara, Cesarini; Andrea, Spallarossa; Angelo, Ranise; Olga, Bruno; Nicoletta, Arduino; Franco, Dallegri; Tognolini, Massimiliano; Barocelli, Elisabetta | |
| 6-amino-4-oxo-1,3-diphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl derivatives as a new class of potent inhibitors of Interleukin-8-induced neutrophil chemotaxis. | 1-gen-2009 | Cesarini, S; Spallarossa, A; Ranise, A; Bruno, O; Arduino, N; Bertolotto, M; Dallegri, F; Tognolini, Massimiliano; Gobbetti, Thomas; Barocelli, Elisabetta | |
| A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence | 1-gen-2023 | Festuccia, Claudio; Corrado, Miriam; Rossetti, Alessandra; Castelli, Riccardo; Lodola, Alessio; Gravina, Giovanni Luca; Tognolini, Massimiliano; Giorgio, Carmine | |
| A photosensitizing fusion protein with targeting capabilities | 1-gen-2022 | Bruno, S.; Margiotta, M.; Cozzolino, M.; Bianchini, P.; Diaspro, A.; Cavanna, L.; Tognolini, M.; Abbruzzetti, S.; Viappiani, C. | |
| A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients | 1-gen-2013 | Caligiani, Augusta; Giulia, Malavasi; Palla, Gerardo Giovanni; Marseglia, Angela; Tognolini, Massimiliano; Bruni, Renato | |
| Accommodation and peristalsis are functional responses to chronic obstruction in rat hypertrophic ileum | 1-gen-2010 | Bertoni, Simona; Flammini, Lisa; Saccani, Francesca; Ballabeni, Vigilio; G., Vegezzi; Tognolini, Massimiliano; Barocelli, Elisabetta | |
| Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. | 1-gen-2013 | Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Noberini, R; Pasquale, Eb; Vicini, Paola; Piersanti, Silvia; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio | |
| Analgesic properties of benzisothiazole/ benzimidazole derivatives with acidic groups | 1-gen-2000 | Vicini, Paola; L., Amoretti; Ballabeni, Vigilio; Tognolini, Massimiliano; Chiavarini, Milena; F., Calcina; Barocelli, Elisabetta |