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Mostrati risultati da 21 a 40 di 69
Titolo Data di pubblicazione Autore(i) File
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. 1-gen-2013 Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Noberini, R; Pasquale, Eb; Vicini, Paola; Piersanti, Silvia; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
Discovery and development of low molecular weight Eph-ephrin protein-protein inhbi-tors endowed with antiangiogenic activity 1-gen-2014 Tognolini, Massimiliano; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Incerti, Matteo; Barocelli, Elisabetta; Bertoni, Simona; Pala, Daniele; Mor, Marco; Russo, Simonetta; Lodola, Alessio
Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction. 1-gen-2014 Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Castelli, Riccardo; Pala, Daniele; Mor, Marco; Barocelli, Elisabetta; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio
Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis 1-gen-2014 HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta; Mor, Marco; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Tognolini, Massimiliano
Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction 1-gen-2014 Pala, Daniele; Castelli, Riccardo; Incerti, Matteo; Russo, Simonetta; Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Zanotti, Ilaria; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio
Target Hopping as a Useful Tool for the Identification of Novel EphA2 Protein–Protein Antagonists 1-gen-2014 Tognolini, Massimiliano; Incerti, Matteo; Pala, Daniele; Russo, Simonetta; Castelli, Riccardo; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Lodola, Alessio
Therapeutic perspectives of Eph–ephrin system modulation 1-gen-2014 Tognolini, Massimiliano; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Zanotti, Ilaria; Lodola, Alessio
270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors 1-gen-2014 Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio
1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5 amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6 carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10Hpyrimido[1,2-a [1,8]naphthyridine-6-carboxamide derivative 1-gen-2014 M., Di Braccio; G., Grossi; S., Alfei; Ballabeni, Vigilio; Tognolini, Massimiliano; Flammini, Lisa; Giorgio, Carmine; Bertoni, Simona; Barocelli, Elisabetta
UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations. 1-gen-2014 HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Incerti, Matteo; Russo, Simonetta; Pala, Daniele; Pasquale, Eb; Zanotti, Ilaria; Vicini, Paola; Barocelli, Elisabetta; Rivara, Silvia; Mor, Marco; Lodola, Alessio; Tognolini, Massimiliano
Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity. 1-gen-2015 Tognolini, Massimiliano; Giorgio, Carmine; Festuccia, C; Rusnati, M; Chiodelli, P; Incerti, Matteo; Pala, Daniele; Callegari, Donatella; Bertoni, Simona; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta
In vitro and in vivo efficacy of an orally bioavailable antagonist of Eph-ephrin system in tumor angiogenesis and growth 1-gen-2015 Giorgio, Carmine; Castelli, Riccardo; Hassan Mohamed, I.; Incerti, Matteo; Vacondio, Federica; Bertoni, Simona; Festuccia, C.; Pala, Daniele; Lodola, Alessio; Barocelli, Elisabetta; Tognolini, Massimiliano
Multiple approaches for the discovery and development of small molecules targeting Eph-ephrin protein-protein interaction 1-gen-2015 Tognolini, Massimiliano; Giorgio, Carmine; Incerti, Matteo; Castelli, Riccardo; Festuccia, C.; Rusnati, M.; Vacondio, Federica; Russo, Simonetta; Pala, Daniele; Callegari, Donatella; Mor, Marco; Bertoni, Simona; Ballabeni, Vigilio; Lodola, Alessio; Barocelli, Elisabetta
Δ5-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system 1-gen-2015 Castelli, Riccardo; Tognolini, Massimiliano; Vacondio, Federica; Incerti, Matteo; Pala, Daniele; Callegari, Donatella; Bertoni, Simona; Giorgio, Carmine; Hassan Mohamed, I; Zanotti, Ilaria; Bugatti, A; Rusnati, M; Festuccia, C; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
The ellagitannin colonic metabolite urolithin D selectively inhibits EphA2 phosphorylation in prostate cancer cells 1-gen-2015 Giorgio, Carmine; MENA PARRENO, Pedro Miguel; DEL RIO, Daniele; Brighenti, Furio; Barocelli, Elisabetta; HASSAN MOHAMED, Iftiin; Callegari, Donatella; Lodola, Alessio; Tognolini, Massimiliano
Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives 1-gen-2015 Kontogiorgis, Christos; Nicolotti, Orazio; Mangiatordi, Giuseppe Felice; Tognolini, Massimiliano; Karalaki, Foteini; Giorgio, Carmine; Patsilinakos, Alexandros; Carotti, Angelo; Hadjipavlou Litina, Dimitra; Barocelli, Elisabetta
Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis 1-gen-2016 Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Bugatti, Antonella; Vacondio, Federica; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Hassan Mohamed, Iftiin; Gioiello, Antimo; Rusnati, Marco; Lodola, Alessio; Tognolini, Massimiliano
Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return 1-gen-2016 Russo, Simonetta; Callegari, Donatella; Incerti, Matteo; Pala, Daniele; Giorgio, Carmine; Brunetti, Jlenia; Bracci, Luisa; Vicini, Paola; Barocelli, Elisabetta; Capoferri, Luigi; Rivara, Silvia; Tognolini, Massimiliano; Mor, Marco; Lodola, Alessio
Eph-ephrin antagonism in tumor angiogenesis and growth: UniPR1331 preclinical evidence. 1-gen-2017 Giorgio, Carmine; Festuccia, Claudio; Gravina, Giovanni L.; Castelli, Riccardo; Rusnati, Marco; Chiodelli, Paola; Vacondio, Federica; Pala, Daniele; Callegari, Donatella; Barocelli, Elisabetta; Lodola, Alessio; Tognolini, Massimiliano
Discovery and development of small molecules targeting Eph-ephrin system in glioblastoma: an academic history 1-gen-2017 Tognolini, Massimiliano; Claudio, Festuccia; Gianluca, Gravina; Castelli, Riccardo; Incerti, Matteo; Vacondio, Federica; Callegari, Donatella; Simonetta, Russo; Barocelli, Elisabetta; Marco, Rusnati; Paola, Chiodelli; Lodola, Alessio; Giorgio, Carmine
Mostrati risultati da 21 a 40 di 69
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