A method is described for producing a cancer-specific cytotoxic antibody directed against one or 5 more randomly targeted, highly antigenic cell surface components embodying one or more unknown glycan moieties, where such components are exclusively expressed by leukemia and/or lymphoma cells, and where the obtained antibody is capable of inducing caspase-dependent regulated cell death when administered in its naked form to such cells.
METHOD FOR THE PRODUCTION OF TUMOR-SPECIFIC ANTIBODIES WITH CYTOTOXIC PROPERTIES / Perris, R., Galati, S., Borghini, N.. - (2026), pp. 1-22.
METHOD FOR THE PRODUCTION OF TUMOR-SPECIFIC ANTIBODIES WITH CYTOTOXIC PROPERTIES
Perris Roberto
;Galati Serena;Borghini Naomi
2026-01-01
Abstract
A method is described for producing a cancer-specific cytotoxic antibody directed against one or 5 more randomly targeted, highly antigenic cell surface components embodying one or more unknown glycan moieties, where such components are exclusively expressed by leukemia and/or lymphoma cells, and where the obtained antibody is capable of inducing caspase-dependent regulated cell death when administered in its naked form to such cells.File in questo prodotto:
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