Cerebrospinal fluid (CSF) kappa free light chains (KFLC) are gaining increasing interest as markers of intrathecal immunoglobulin synthesis. The main aim of this study was to assess the diagnostic accuracy (AUC) of the kappa index (CSF/serum KFLC divided by the CSF/serum albumin ratio) compared to CSF oligoclonal IgG bands (OCB) in predicting Multiple Sclerosis (MS) or a central nervous system infectious/inflammatory disorder (CNSID).

Kappa Index Versus CSF Oligoclonal Bands in Predicting Multiple Sclerosis and Infectious/Inflammatory CNS Disorders / Ferraro, D., Bedin, R., Natali, P., Franciotta, D., Smolik, K., Santangelo, M., Immovilli, P., Camera, V., Vitetta, F., Gastaldi, M., Trenti, T., Meletti, S., Sola, P.. - In: DIAGNOSTICS. - ISSN 2075-4418. - 10:10(2020), pp. 000-011. [10.3390/diagnostics10100856]

Kappa Index Versus CSF Oligoclonal Bands in Predicting Multiple Sclerosis and Infectious/Inflammatory CNS Disorders

Meletti, Stefano;
2020-01-01

Abstract

Cerebrospinal fluid (CSF) kappa free light chains (KFLC) are gaining increasing interest as markers of intrathecal immunoglobulin synthesis. The main aim of this study was to assess the diagnostic accuracy (AUC) of the kappa index (CSF/serum KFLC divided by the CSF/serum albumin ratio) compared to CSF oligoclonal IgG bands (OCB) in predicting Multiple Sclerosis (MS) or a central nervous system infectious/inflammatory disorder (CNSID).
2020
Kappa Index Versus CSF Oligoclonal Bands in Predicting Multiple Sclerosis and Infectious/Inflammatory CNS Disorders / Ferraro, D., Bedin, R., Natali, P., Franciotta, D., Smolik, K., Santangelo, M., Immovilli, P., Camera, V., Vitetta, F., Gastaldi, M., Trenti, T., Meletti, S., Sola, P.. - In: DIAGNOSTICS. - ISSN 2075-4418. - 10:10(2020), pp. 000-011. [10.3390/diagnostics10100856]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/3058120
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 46
  • ???jsp.display-item.citation.isi??? 47
social impact