Photonic crystal fiber (PCF) can be used as a microfluidic platform for surface-enhanced Raman spectroscopy (SERS)-based measurement of different samples. PCF can provide a long area of interaction for light, metal nanoparticles (NPs), and analytes incorporated into its holes. This paper provides a COMSOL simulation model for suspended-core PCF used to evaluate the SERS intensity depending on the fiber's geometry and NPs' coverage density. The simulation is applied to compare three PCFs with varying sizes and lengths. SERS measurements of adenine and DNA validate the simulation outcomes and demonstrate the potential of PCFs for SERS-based detection of diverse samples.
Suspended-core photonic crystal fibers for SERS detection of biomolecules / Issatayeva, A.; Mariyam, S.; Kho, K. W.; Andersson-Engels, S.; Cucinotta, A.. - In: JOURNAL OF OPTICS. - ISSN 2040-8978. - 27:4(2025), p. 045301. [10.1088/2040-8986/ada9fe]
Suspended-core photonic crystal fibers for SERS detection of biomolecules
Issatayeva A.
Membro del Collaboration Group
;Cucinotta A.
2025-01-01
Abstract
Photonic crystal fiber (PCF) can be used as a microfluidic platform for surface-enhanced Raman spectroscopy (SERS)-based measurement of different samples. PCF can provide a long area of interaction for light, metal nanoparticles (NPs), and analytes incorporated into its holes. This paper provides a COMSOL simulation model for suspended-core PCF used to evaluate the SERS intensity depending on the fiber's geometry and NPs' coverage density. The simulation is applied to compare three PCFs with varying sizes and lengths. SERS measurements of adenine and DNA validate the simulation outcomes and demonstrate the potential of PCFs for SERS-based detection of diverse samples.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
