Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200 cells/μL while individuals with CD4 <200 cells/μL showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients.

Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients / Fabbiani, M., Di Giambenedetto, S., Sali, M., Farina, S., Sansonetti, P., Tamburrini, E., Dal Verme, L.z., Delogu, G., De Luca, A., Kelvin, D., Cauda, R., Fadda, G.. - In: VACCINE. - ISSN 0264-410X. - 29:16(2011), pp. 2836-2839. [http://dx.doi.org/10.1016/j.vaccine.2011.02.020]

Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients

Delogu G;
2011-01-01

Abstract

Immunogenicity of influenza A (H1N1)v MF59-adjuvanted vaccine was studied in HIV-infected patients. The vaccine was effective in inducing a protective immune response in patients with a CD4 >200 cells/μL while individuals with CD4 <200 cells/μL showed lower rates of seroconversion and seroprotection. These results underscore the usefulness of immunization against influenza in HIV-infected patients, though a boosting dose of vaccine may be required in seriously immunocompromised patients.
2011
Immune response to influenza A (H1N1)v monovalent MF59-adjuvanted vaccine in HIV-infected patients / Fabbiani, M., Di Giambenedetto, S., Sali, M., Farina, S., Sansonetti, P., Tamburrini, E., Dal Verme, L.z., Delogu, G., De Luca, A., Kelvin, D., Cauda, R., Fadda, G.. - In: VACCINE. - ISSN 0264-410X. - 29:16(2011), pp. 2836-2839. [http://dx.doi.org/10.1016/j.vaccine.2011.02.020]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/3022618
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 33
  • ???jsp.display-item.citation.isi??? 10
social impact