OBJECTIVES: The TRI-SCORE is a recently published risk score for predicting in-hospital mortality in patients undergoing isolated tricuspid valve surgery (ITVS). The aim of this study is to externally validate the ability of the TRI-SCORE in predicting in-hospital and long-Term mortality following ITVS. METHODS: A retrospective review of our institutional database was carried out to identify all patients undergoing isolated tricuspid valve repair or replacement from March 1997 to March 2021. The TRI-SCORE was calculated for all patients. Discrimination of the TRI-SCORE was assessed using receiver operating characteristic curves. Accuracy of the models was tested calculating the Brier score. Finally, a COX regression was employed to evaluate the relationship between the TRI-SCORE value and long-Term mortality. RESULTS: A total of 176 patients were identified and the median TRI-SCORE was 3 (1-5). The cut-off value identified for increased risk of isolated ITVS was 5. Regarding in-hospital outcomes, the TRI-SCORE showed high discrimination (area under the curve 0.82), and high accuracy (Brier score 0.054). This score showed also very good performance in predicting long-Term mortality (at 10 years, hazard ratio: 1.47, 95% confidence interval [1.31-1.66], P < 0.001), with high discrimination (area under the curve >0.80 at 1-5 and 10 years) and high accuracy values (Brier score 0.179). CONCLUSIONS: This external validation confirms the good performance of the TRI-SCORE in predicting in-hospital mortality. Moreover, the score showed also very good performance in predicting the long-Term mortality.

TRI-SCORE: A single-centre validation study / Sala, A.; Carino, D.; Lorusso, R.; Zancanaro, E.; Bargagna, M.; Del Forno, B.; Trumello, C.; Denti, P.; Ruggeri, S.; Nonis, A.; Scarale, M. G.; Schiavi, D.; Castiglioni, A.; Maisano, F.; Alfieri, O.; De Bonis, M.. - In: INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY. - ISSN 2753-670X. - 36:6(2023). [10.1093/icvts/ivad085]

TRI-SCORE: A single-centre validation study

Carino D.;
2023-01-01

Abstract

OBJECTIVES: The TRI-SCORE is a recently published risk score for predicting in-hospital mortality in patients undergoing isolated tricuspid valve surgery (ITVS). The aim of this study is to externally validate the ability of the TRI-SCORE in predicting in-hospital and long-Term mortality following ITVS. METHODS: A retrospective review of our institutional database was carried out to identify all patients undergoing isolated tricuspid valve repair or replacement from March 1997 to March 2021. The TRI-SCORE was calculated for all patients. Discrimination of the TRI-SCORE was assessed using receiver operating characteristic curves. Accuracy of the models was tested calculating the Brier score. Finally, a COX regression was employed to evaluate the relationship between the TRI-SCORE value and long-Term mortality. RESULTS: A total of 176 patients were identified and the median TRI-SCORE was 3 (1-5). The cut-off value identified for increased risk of isolated ITVS was 5. Regarding in-hospital outcomes, the TRI-SCORE showed high discrimination (area under the curve 0.82), and high accuracy (Brier score 0.054). This score showed also very good performance in predicting long-Term mortality (at 10 years, hazard ratio: 1.47, 95% confidence interval [1.31-1.66], P < 0.001), with high discrimination (area under the curve >0.80 at 1-5 and 10 years) and high accuracy values (Brier score 0.179). CONCLUSIONS: This external validation confirms the good performance of the TRI-SCORE in predicting in-hospital mortality. Moreover, the score showed also very good performance in predicting the long-Term mortality.
2023
TRI-SCORE: A single-centre validation study / Sala, A.; Carino, D.; Lorusso, R.; Zancanaro, E.; Bargagna, M.; Del Forno, B.; Trumello, C.; Denti, P.; Ruggeri, S.; Nonis, A.; Scarale, M. G.; Schiavi, D.; Castiglioni, A.; Maisano, F.; Alfieri, O.; De Bonis, M.. - In: INTERDISCIPLINARY CARDIOVASCULAR AND THORACIC SURGERY. - ISSN 2753-670X. - 36:6(2023). [10.1093/icvts/ivad085]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/3016096
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