Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystemic, immune-mediated disease that occurs in patients with asthma and eosinophilia. It is characterized by inflammation of small- and medium-caliber blood vessels. Case report: This report presents an unusual clinical case of EGPA with positive anti-neutrophil cytoplasmic antibodies who manifested bilateral pleural effusion. The diagnosis was confirmed through laboratory assessments and bronchial biopsies. The patient was treated with methylprednisolone showing improvement in symptoms. Conclusions: Our case appear interesting considering the limited evidence of pleural effusion in patients with EGPA documented in the literature.
Onset of ANCA-positive EGPA with bilateral pleural effusion: a case report / Marchese, A., Accogli, R., Frizzelli, A., DE SIMONI, A., Bondarenko, O., Pisi, R., Caramori, G., Pela', G., Majori, M., Gnetti, L., Aluia, A., D’Aloisio, L., Chetta, A., Aiello, M.. - In: CURRENT MEDICAL RESEARCH AND OPINION. - ISSN 1473-4877. - Article 2427882(2024). [10.1080/03007995.2024.2427882]
Onset of ANCA-positive EGPA with bilateral pleural effusion: a case report
Alessandra Marchese;Rocco Accogli;Annalisa Frizzelli;Alessandro De Simoni;Olha Bondarenko;Roberta Pisi;Gaetano Caramori;Giovanna Pela';Maria Majori;Letizia Gnetti;Agnese Aluia;Lorenzo D’Aloisio;Alfredo Chetta;Marina Aiello
2024-01-01
Abstract
Background: Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystemic, immune-mediated disease that occurs in patients with asthma and eosinophilia. It is characterized by inflammation of small- and medium-caliber blood vessels. Case report: This report presents an unusual clinical case of EGPA with positive anti-neutrophil cytoplasmic antibodies who manifested bilateral pleural effusion. The diagnosis was confirmed through laboratory assessments and bronchial biopsies. The patient was treated with methylprednisolone showing improvement in symptoms. Conclusions: Our case appear interesting considering the limited evidence of pleural effusion in patients with EGPA documented in the literature.| File | Dimensione | Formato | |
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